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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

H19 Gene

RNA gene GIFtS: 39
GCID: GC11M002016

H19, imprinted maternally expressed transcript (non-protein...

(Previous names: H19, imprinted maternally expressed untranslated mRNA )

Explore 79 diseases affiliated with
H19 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Subcategory (RNA class): lncRNA

Quality score for this RNA gene is 5

Aliases
H19, Imprinted Maternally Expressed Transcript (Non-Protein Coding)¹ ²		NCRNA00008¹ ²
ASM1¹ ² ⁵		BWS² ⁵
D11S813E¹ ² ⁵		WT2² ⁵
ASM¹ ²		H19, Imprinted Maternally Expressed Untranslated MRNA¹
LINC00008¹ ²		PRO2605²

External Ids:	HGNC: 4713¹	Entrez Gene: 283120²	Ensembl: ENSG00000130600⁷	OMIM: 103280⁵

ORGUL members:	fRNAdb¹⁰:FR143442 FR378527 FR217109 FR041821 FR401793
	H-InvDB:HIT000338440
	NCBI:AF087017 AF125183 AF087017 M32053 BC106079
	NONCODE:u745 u837 u4124 n333410 n343066	see all 7
	RNAdb:LIT1610 LIT1609

Export aliases for H19 gene to outside databases

Previous GC identifers: GC11U990149 GC11M001980 GC11M001972 GC11M001976 GC11M001807

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for H19:

This gene expresses a non-coding RNA, and functions as a tumor suppressor. The gene is located in an imprinted region

of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. Expression of this gene and IGF2 are imprinted so

that this gene is only expressed from the maternally-inherited chromosome, and IGF2 is only expressed from the

paternally-inherited chromosome. A region of paternal-specific methylation upstream of this gene is required for the

imprinting of these genes. Mutations in this gene are associated with Beckwith-Wiedemann Syndrome and Wilms

tumorigenesis. (provided by RefSeq, Mar 2009)

Gene Wiki entry for H19

fRNAdb sequence ontologies for H19 - the ORGUL cluster for this gene includes several descriptions:
ncRNA - An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product.
mature_transcript - A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified.

View fRNAdb secondary structures for H19

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the H19 gene promoter:
NF-1 NF-1/L p53 MyoD
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for H19

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat H19

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5

H19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
H19 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M002016: view genomic region (about GC identifiers)

Start:	2,016,406 bp from pter	End:	2,022,700 bp from pter
Size:	6,295 bases	Orientation:	minus strand

ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for H19

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB: --

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

Genatlas biochemistry entry for H19:

DNA segment,single copy,probe H19S1,highly expressed in endodermal and mesodermal embryonic tissues,in adult brain,only

in the pons and globus pallidus,paternally imprinted,(?same as ASMG),telomeric imprinting domain at 11p15,containing

ASCL2,IGF2 and H19,silenced and hypermethylated in most Wilms tumor and in bladder carcinomas,but hypomethylated in

benign ovarian teratoma

Phenotypes:
15/19 MGI mutant phenotypes (inferred from 29 alleles) (MGI details for H19) (see all 19):

cardiovascular system	cellular	craniofacial	digestive/alimentary	embryogenesis
endocrine/exocrine gland	growth/size	homeostasis/metabolism	limbs/digits/tail	liver/biliary system
mortality/aging	muscle	nervous system	no phenotypic analysis	normal

H19 for phenotypes           About GeneDecksing

Animal Models:
     Mouse knock-outs for H19: H19^tm1Rohl H19^tm7Tilg H19^tm7Msb H19^tm3Msb H19^tm5Msb H19^tm2Wrk
                                               H19^tm1Msb H19^tm1.1Sriv H19^tm6Msb H19^tm1Lda H19^tm1.1Kpfe H19^tm1Tilg H19^tm4Msb
                                               H19^tm1.1Msb H19^tm2Tilg H19^tm1Masu

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for H19

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat H19
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for H19 OriGene shRNA RFP: H19 OriGene siRNA: H19
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Gene Editing
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DNA2.0 Custom Protein Engineering Service for H19

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		GenScript Custom all cDNA clones Services for H19
		Browse Sino Biological Human cDNA Clones
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		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for H19
		Search LifeMap BioReagents cell lines for H19

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for H19

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

H19 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for H19
10/18 Novoseek chemical compound relationships for H19 gene (see all 18) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
nap-2	78.3	3	9268640 (1), 9618174 (1), 10049585 (1)
apai	73.6	8	13679437 (1), 9570364 (1), 10473973 (1), 10738131 (1) (see all 7)
rsai	68.4	12	13679437 (1), 10690526 (1), 8564957 (1), 10473973 (1) (see all 8)
cytosine	47.1	3	11889182 (2), 9310237 (1)
5-aza-2'deoxycytidine	45.5	5	16707479 (1), 8842727 (1), 11889182 (1), 11726548 (1)
n-butyl-n-(4-hydroxybutyl)nitrosamine	41.8	2	9886562 (2)
hpaii	37.8	1	17020468 (1)
paraffin	13.8	6	9025899 (1), 9208812 (1), 7855987 (1), 10428315 (1) (see all 6)
ribonucleic acid	7.2	4	9177379 (2), 10843195 (1), 12534338 (1)
acth	5.62	6	7512497 (2), 7531713 (2), 9177379 (2)

Search CenterWatch for drugs/clinical trials and news about H19

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

1 fRNAdb Secondary structure:

Unigene Cluster for H19:

H19, imprinted maternally expressed transcript (non-protein coding)

Hs.533566 [show with all ESTs]

Unigene Representative Sequence: NR_002196

14 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000414790(lincRNA)(uc021qby.1 uc001lva.4 uc021qbz.1) ENST00000412788(lincRNA)

ENST00000439725(lincRNA) ENST00000411861(lincRNA) ENST00000417089(lincRNA) ENST00000446406(lincRNA) ENST00000431095(lincRNA)

ENST00000411754(lincRNA) ENST00000422826(lincRNA) ENST00000428066(lincRNA) ENST00000436715(lincRNA) ENST00000447298(lincRNA)

ENST00000442037(lincRNA) ENST00000535745(lincRNA)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat H19
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate H19
		Browse SwitchGear 3'UTR luciferase reporter plasmids

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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for H19 OriGene shRNA RFP: H19 OriGene siRNA: H19
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat H19

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for H19 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for H19
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for H19
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat H19

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for H19 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat H19
		Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat H19
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H19

Additional cDNA sequence:

AK056774.1 AK092486.1 AK123560.1 AK309887.1 AK311497.1 BC006831.1 BC007513.2 BC009853.1

BC010185.2 BC013067.1 BC015952.2 BC023213.1 BC040073.1 BC040852.1 BC053636.1 BC053637.1

BC063564.1 BC063626.1 BC069247.1 BC098439.1 BC106078.1 BC106079.1 BC110657.1 BC115700.1

NR_002196.1

24/108 DOTS entries (see all 108):

DT.95378063 DT.91915935 DT.100876775 DT.95378256 DT.100743662 DT.91731337 DT.85104197 DT.100743626

DT.100743767 DT.85101650 DT.455239 DT.92470792 DT.92391664 DT.120706266 DT.120706354 DT.95378206

DT.102841233 DT.120706331 DT.100743769 DT.91656375 DT.100743606 DT.100743661 DT.92051978 DT.100743632

24/2627 AceView cDNA sequences (see all 2627):

N92128 AA479645 CR608274 BE280752 BM698178 AW675662 BF839797 R71588

AL573822 CR600700 BX406387 BE900540 CR605723 BE280959 H51643 H68737

BG773568 CR613250 CR594717 H59450 H67884 BX343807 CB990149 CR610115

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

Expression evidence for H19:RNAdb

H19 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCACCCCCT

About this image

H19 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

9 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Liver

Liver

Liver

Epicardium

Kidney Endothelial Cells

Endothelium

Pancreas

Dorsal Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Ventral Pancreatic Bud

Immature Beta Progenitor Cells

Pancreas

Testis

Interscapular Brown Adipose Depot

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 10/23 LifeMap Cells (see all 23)

Name

Category

HSF-1 (UC01) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

PureStem™ myogenic progenitor Z11 (Embryonic Progenitor Cell)

Heart, Myocardium, Smooth Muscle

PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)

Cartilage, Neural Crest

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

PureStem™ progenitor E69 (Embryonic Progenitor Cell)

PureStem™ progenitor EN13 (Embryonic Progenitor Cell)

PureStem™ progenitor EN2 (Embryonic Progenitor Cell)

PureStem™ progenitor EN7 (Embryonic Progenitor Cell)

PureStem™ progenitor RASMO12 (Embryonic Progenitor Cell)

Genevestigator expression for H19

SOURCE GeneReport for Unigene cluster: Hs.533566

SABiosciences Custom PCR Arrays for H19

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for H19 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat H19

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for H19

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for H19 gene from 1 species (see representative species ) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	H19⁵	H19 fetal liver mRNA	--		7 (87.97 cM) 142575529

ENSEMBL Gene Tree for H19 (if available)
TreeFam Gene Tree for H19 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Pop	Total sample
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs72556550^1,2	F	--	1807696(-)	`RGTRCG/AAGTGT`	1	--	nc-transcript-variant		5	MN	408
rs72556551^1,2	F	--	1807706(-)	`CTTGAG/ATCTCR`	1	--	nc-transcript-variant		5	MN	408
rs113046940^1,2	C	--	1808139(+)	`CTGGTC/GCTCAC`	1	--	int¹		1	CSA	1
rs112056845^1,2	C	--	1808140(+)	`TGGTGC/G/TTCACC`	1	--	int¹		1	CSA	1
rs12577355^1,2	H	--	1808261(+)	`GTAGCA/CCCATT`	1	--	nc-transcript-variant		4	NS EA	394
rs113390616^1,2	C	--	1808347(+)	`CCTCAC/G/TCTTTC`	1	--	spd¹		1	CSA	1
rs2668850^1,2	C	--	1808498(-)	`YGSCGG/CGCCAC`	1	--	int¹		5	MN	408
rs2735969^1,2	C	--	1808501(-)	`CCCYGC/GCGSGC`	1	--	int¹		5	MN	364
rs115696222^1,2	C,F	--	1809225(+)	`CTCCCC/TGAGCA`	1	--	nc-transcript-variant		1	WA	118
rs11542717^1,2	C	--	1809265(-)	`TGCCGG/TAGCCT`	1	--	nc-transcript-variant		5	MN	392

HapMap Linkage Disequilibrium report for H19 (2016406 - 2022700 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for H19
2 CNVs: 29891 29893
Human Gene Mutation Database (HGMD): H19

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing H19

DNA2.0 Custom Variant and Variant Library Synthesis for H19

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

H19 for disorders           About GeneDecksing

OMIM gene information: 103280OMIM information: 194071 604499 607967 609270 609470
OMIM disorders: 130650  180860  194071
20/79 diseases for H19 (see all 79):    About MalaCards

beckwith-wiedemann syndrome silver-russell syndrome malignant mixed mullerian tumor germ cell tumor

pre-eclampsia hemihypertrophy testicular germ cell tumor adrenal adenoma

birth defects wilms tumor spontaneous abortion premature ovarian failure

myeloproliferative disorder laryngeal squamous cell carcinoma angiomatosis wilms tumor 2

wagr syndrome clear cell sarcoma cystadenoma squamous cell carcinoma

10/62 Novoseek disease relationships for H19 gene (see all 62) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
beckwith-wiedemann syndrome	92.4	19	9285792 (2), 8971182 (1), 10857747 (1), 15057946 (1) (see all 18)
embryonal tumor	79.8	2	8618347 (1), 11751681 (1)
wilms tumor	79.7	37	10506193 (3), 7534414 (2), 17325026 (2), 8842727 (2) (see all 24)
cancer embryonal	79	1	9484911 (1)
pediatric germ cell tumor	65.8	1	10189147 (1)
hepatoblastoma	63.1	12	10404060 (4), 10732739 (2), 9570364 (1), 19034281 (1) (see all 8)
hydatidiform mole	59.5	8	7866996 (3), 8188082 (1), 10751088 (1), 10022954 (1) (see all 5)
rhabdomyosarcoma embryonal	57.9	1	12234381 (1)
hemihypertrophy	49.8	2	16532391 (1), 7802016 (1)
bladder carcinoma	49	29	7589512 (5), 11193051 (4), 9886562 (3), 10413100 (3) (see all 9)

GeneTests: H19

Beckwith-Wiedemann Syndrome

Russell-Silver Syndrome

Genetic Association Database (GAD): H19
Human Genome Epidemiology (HuGE) Navigator: H19 (13 documents)

Export disorders for H19 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for H19 gene, integrated from 9 sources (see all 373):
(articles sorted by number of sources associating them with H19)

Utopia: connect your pdf to the dynamic
world of online information

The product of the H19 gene may function as an RNA. (PubMed id 1688465)^{1, 3, 9} Brannan C.I....Tilghman S.M. (1990)
Common polymorphism in H19 associated with birthweight and cord blood IGF-II levels in humans. (PubMed id 15885138)^{1, 4} Petry C.J....Dunger D.B. (2005)
A fine-structure deletion map of human chromosome 11p: analysis of J1 series hybrids. (PubMed id 2595451)^{1, 3} Glaser T....Jones C. (1989)
The H19 gene imprinting in normal pregnancy and pre-eclampsia. (PubMed id 19342096)^{1, 9} Yu L....Li L. (2009)
Association of H19 promoter methylation with the expression of H19 and IGF-II genes in adrenocortical tumors. (PubMed id 11889182)^{1, 9} Gao Z.H....Voutilainen R. (2002)
The H19 non-coding RNA is essential for human tumor growth. (PubMed id 17786216)^{1, 9} Matouk I.J....Galun E. (2007)
[The aberrant imprinting of insulin-like growth factor II and H19 in human hepatocellular carcinoma] (PubMed id 17294726)^{1, 9} Wu J....Sun Z.L. (2007)
Expression of the imprinted IGF2 and H19 genes in the endometrium of cases with unexplained infertility. (PubMed id 20042264)^{1, 9} Korucuoglu U....Menevse S. (2010)
[VIGILIN involves in regulation of imprinting gene IG F2 and H19 in human hepatocellular carcinoma cell] (PubMed id 19950580)^{1, 9} Ge Y.J....Qin Y. (2009)
Homocysteine harasses the imprinting expression of IG F2 and H19 by demethylation of differentially methylated region between IGF2/H1 9 genes. (PubMed id 19499149)^{1, 9} Li L....Wang S. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 283120	HGNC: 4713	AceView: H19	Ensembl:ENSG00000130600	euGenes: HUgn283120
ECgene: H19	H-InvDB: H19

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for H19	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for H19	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for H19 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for H19 gene:
Search GeneIP for patents involving H19

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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H19 Proteins, Antibodies, CLIAs, and ELISAs

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H19 Gene

H19, imprinted maternally expressed transcript (non-protein...

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H19 Gene

H19, imprinted maternally expressed transcript (non-protein...

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