Aliases for GZMK Gene
External Ids for GZMK Gene
This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. [provided by RefSeq, Jul 2008]
GeneCards Summary for GZMK Gene
GZMK (Granzyme K (Granzyme 3; Tryptase II)) is a Protein Coding gene. Diseases associated with GZMK include arts syndrome and t-cell large granular lymphocyte leukemia. Among its related pathways are Granzyme Pathway. GO annotations related to this gene include serine-type endopeptidase activity and serine-type peptidase activity. An important paralog of this gene is ELANE.