Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



GZF1 Gene

protein-coding   GIFtS: 44
GCID: GC20P023342

GDNF-Inducible Zinc Finger Protein 1

(Previous name: zinc finger protein 336)
(Previous symbol: ZNF336)
  Search for GZF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
GDNF-Inducible Zinc Finger Protein 11 2
ZNF3361 2 3 5
Zinc Finger Protein 3361 2 3
Zinc Finger And BTB Domain-Containing Protein 232 3
ZBTB232 3

External Ids:    HGNC: 158081   Entrez Gene: 644122   Ensembl: ENSG000001258127   OMIM: 6138425   UniProtKB: Q9H1163   

Export aliases for GZF1 gene to outside databases

Previous GC identifer: GC20P023291


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for GZF1 Gene:
GZF1 (GDNF-inducible zinc finger protein 1) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding.

UniProtKB/Swiss-Prot: GZF1_HUMAN, Q9H116
Function: Transcriptional repressor. Binds the GZF1 responsive element (GRE) (consensus:
5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the GZF1 gene promoter:
         Pax-5   Nkx2-5   LCR-F1   POU3F2   C/EBPalpha   Max   FOXO1a   FOXO1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGZF1 promoter sequence
   Search Chromatin IP Primers for GZF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GZF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p11.21   Ensembl cytogenetic band:  20p11.21   HGNC cytogenetic band: 20p11.21

GZF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GZF1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P023342:  view genomic region     (about GC identifiers)

Start:
23,342,787 bp from pter      End:
23,353,700 bp from pter
Size:
10,914 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: GZF1_HUMAN, Q9H116 (See protein sequence)
Recommended Name: GDNF-inducible zinc finger protein 1  
Size: 711 amino acids; 80492 Da
Subunit: Interacts with NCL
Sequence caution: Sequence=BAB15134.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAB71107.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8K199 B2RBC3 B3KPL4 D3DW39 Q54A22 Q96N08 Q9BQK9 Q9H117 Q9H6W6

Explore the universe of human proteins at neXtProt for GZF1: NX_Q9H116

Explore proteomics data for GZF1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GZF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_071927.1  
    ENSEMBL proteins: 
     ENSP00000338290   ENSP00000410009   ENSP00000366250   ENSP00000445458   ENSP00000445118  

    GZF1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for GZF1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for GZF1
    GenScript Custom Purified and Recombinant Proteins Services for GZF1
    Novus Biologicals GZF1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GZF1

     
    Search eBioscience for Proteins for GZF1 

    GZF1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for GZF1
    OriGene Custom Antibody Services for GZF1
    Novus Biologicals GZF1 Antibody
    Search for Antibodies for GZF1 at Abcam
    Cloud-Clone Corp. Antibodies for GZF1
    ThermoFisher Antibodies for GZF1
    LSBio Antibodies in human, mouse, rat for GZF1

    GZF1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for GZF1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GZF1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for GZF1
    Cloud-Clone Corp. CLIAs for GZF1
    Search eBioscience for ELISAs for GZF1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    BTBD: BTB/POZ domain containing
    ZNF: Zinc fingers, C2H2-type

    Selected InterPro protein domains (see all 6):
     IPR000210 BTB/POZ-like
     IPR015880 Znf_C2H2-like
     IPR011333 BTB/POZ_fold
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR013069 BTB_POZ

    Graphical View of Domain Structure for InterPro Entry Q9H116

    ProtoNet protein and cluster: Q9H116

    1 Blocks protein domain: IPB000210 BTB/POZ domain

    UniProtKB/Swiss-Prot: GZF1_HUMAN, Q9H116
    Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family
    Similarity: Contains 1 BTB (POZ) domain
    Similarity: Contains 10 C2H2-type zinc fingers


    Find genes that share domains with GZF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GZF1_HUMAN, Q9H116
    Function: Transcriptional repressor. Binds the GZF1 responsive element (GRE) (consensus:
    5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression
    Induction: By GDNF

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0005515protein binding ----
    GO:0043565sequence-specific DNA binding IDA16049025
    GO:0046872metal ion binding IEA--
         
    Find genes that share ontologies with GZF1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for GZF1:
     Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GZF1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GZF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GZF1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GZF1

    miRNA
    Products:
        
    miRTarBase miRNAs that target GZF1:
    hsa-let-7b-5p (MIRT005048), hsa-mir-30c-5p (MIRT047985)

    Block miRNA regulation of human, mouse, rat GZF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GZF1 (see all 35):
    hsa-miR-3607-3p hsa-miR-1197 hsa-miR-548k hsa-miR-513a-5p hsa-miR-30d hsa-miR-30a hsa-miR-124 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidGZF1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for GZF1
    Predesigned siRNA for gene silencing in human, mouse, rat GZF1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GZF1

    Clone
    Products:
         
    OriGene clones in human, mouse for GZF1 (see all 7)
    OriGene ORF clones in mouse, rat for GZF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GZF1 (NM_022482)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GZF1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GZF1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for GZF1
    Browse ESI BIO Cell Lines and PureStem Progenitors for GZF1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GZF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    GZF1_HUMAN, Q9H116: Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Nuclear localization depends upon NCL
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm IEA--
    GO:0005730nucleolus IEA--

    Find genes that share ontologies with GZF1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GZF1
    Interactions:

        Search GeneGlobe Interaction Network for GZF1

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0001658branching involved in ureteric bud morphogenesis IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0045892negative regulation of transcription, DNA-templated IDA16049025

    Find genes that share ontologies with GZF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GZF1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for GZF1 gene: 
    NM_022482.3  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338121(uc010gdb.3 uc002wsy.3 uc010zsq.2 uc010zsr.2 uc002wsz.3)
    ENST00000424216 ENST00000461789 ENST00000477239 ENST00000377051 ENST00000544236
    ENST00000542987
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GZF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GZF1 (see all 35):
    hsa-miR-3607-3p hsa-miR-1197 hsa-miR-548k hsa-miR-513a-5p hsa-miR-30d hsa-miR-30a hsa-miR-124 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidGZF1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for GZF1
    Predesigned siRNA for gene silencing in human, mouse, rat GZF1
    Clone
    Products:
         
    OriGene clones in human, mouse for GZF1 (see all 7)
    OriGene ORF clones in mouse, rat for GZF1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GZF1 (NM_022482)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GZF1
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GZF1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for GZF1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GZF1
      QuantiTect SYBR Green Assays in human, mouse, rat GZF1
      QuantiFast Probe-based Assays in human, mouse, rat GZF1

    Selected AceView cDNA sequences (see all 87):

    BQ003583 F12168 AW086480 AA062926 BQ003210 AV686075 CK430798 BQ003649 
    T65259 BI918257 AL046380 AA417012 AB100265 AA701588 AI680505 BU187509 
    NM_022482 AL046381 AI217180 AL135709 BG718371 BG758706 AA346014 AW003181 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GZF1 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c · 9d · 9e
    SP1:                    -     -     -     -     -     -           -                                                   
    SP2:                                                              -                                                   
    SP3:                    -     -     -     -     -     -     -     -                                                   
    SP4:                                                              -                 -                                 
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for GZF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    GZF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTCACACCT
    GZF1 Expression
    About this image

    GZF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GZF1 Protein Expression

    UniProtKB/Swiss-Prot: GZF1_HUMAN, Q9H116
    Tissue specificity: Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal
    brain and kidney, and at lower levels in fetal lung and liver

        Custom PCR Arrays for GZF1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GZF1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GZF1
    QuantiTect SYBR Green Assays in human, mouse, rat GZF1
    QuantiFast Probe-based Assays in human, mouse, rat GZF1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GZF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for GZF1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gzf11 , 5 GDNF-inducible zinc finger protein 11, 5 81.75(n)1
    82.84(a)1
      2 (73.53 cM)5
    745331  NM_028986.31  NP_083262.11 
     1486810235 
    chicken
    (Gallus gallus)
    Aves ZNF5681 zinc finger protein 568 74.61(n)
    78.77(a)
      421233  XM_003640887.2  XP_003640935.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.335852 Xenopus laevis transcribed sequence with moderate similarity more 77.7(n)    BX850650.1 
    zebrafish
    (Danio rerio)
    Actinopterygii hnrnpa0l6
    heterogeneous nuclear ribonucleoprotein A0, like
    41(a)
    1 ↔ 1
    20(45816824-45829720) ENSDARG00000076380


    ENSEMBL Gene Tree for GZF1 (if available)
    TreeFam Gene Tree for GZF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for GZF1 gene
    Selected SIMAP similar genes for GZF1 using alignment to 4 protein entries:     GZF1_HUMAN (see all proteins) (see all similar genes):
    ZSCAN9    kr-znf3    ZNF    ZIK1    ZNF146    ZNF732
    ZNF78L1    ZFS-4    ZNF473    ZNF485    ZNF720    ZNF79
    ZNF808    ZNF852    DKFZp666C237    ZNF22    ZNF600    ZNF768

    Find genes that share paralogs with GZF1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for GZF1 (see all 288)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1884319401,2
    --23343357(+) TGCCAA/GTGAGA 1 -- us2k10--------
    rs1503432571,2
    --23343378(+) ACGCAC/GCTGTC 1 -- us2k10--------
    rs1116676601,2
    C,F--23343411(+) GCCACC/TTCCAG 1 -- us2k12Minor allele frequency- T:0.08CSA WA 120
    rs48151981,2
    C,F,A,H--23343491(+) AGGTCC/TCCTCG 1 -- us2k116Minor allele frequency- T:0.27NS EA NA WA CSA 787
    rs1928538431,2
    C--23343504(+) GGCCCC/TGTTGG 1 -- us2k10--------
    rs1139111581,2
    C,F--23343722(+) TACAGG/CGGAAC 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1491082041,2
    --23343753(+) CATGTG/TTGAGG 1 -- us2k10--------
    rs60830881,2
    C,F,A,H--23343793(+) GATGAG/TACTGG 1 -- us2k112Minor allele frequency- T:0.27NS EA NA CSA WA 786
    rs1449154761,2
    --23344036(+) GTGACG/TGTATC 1 -- us2k10--------
    rs60830891,2
    H--23344132(+) CAAGGC/ATGAGG 1 -- us2k14Minor allele frequency- A:0.00NS EA 420

    HapMap Linkage Disequilibrium report for GZF1 (23342787 - 23353700 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GZF1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GZF1
    DNA2.0 Custom Variant and Variant Library Synthesis for GZF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613842    OMIM disorders: --


    Find genes that share disorders with GZF1           About GenesLikeMe

    Genetic Association Database (GAD): GZF1

    Export disorders for GZF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for GZF1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with GZF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GDNF-inducible zinc finger protein 1 is a sequence-specific transcriptional repressor that binds to the HOXA10 gene regulatory region. (PubMed id 16049025)1, 2, 3, 9 Morinaga T.... Takahashi M. (Nucleic Acids Res. 2005)
    2. Identification of a novel glial cell line-derived neurotrophic factor-inducible gene required for renal branching morphogenesis. (PubMed id 14522971)1, 2, 3 Fukuda N.... Takahashi M. (J. Biol. Chem. 2003)
    3. Nucleolin modulates the subcellular localization of GDNF-inducible zinc finger protein 1 and its roles in transcription and cell proliferation. (PubMed id 17674968)1, 2, 9 Dambara A.... Takahashi M. (Exp. Cell Res. 2007)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma. (PubMed id 21248752)2 Varela I....Futreal P.A. (Nature 2011)
    8. Analysis of glial cell line-derived neurotrophic factor-inducible zinc finger protein 1 expression in human diseased kidney. (PubMed id 21292309)1 Saito S....Takahashi M. (Hum. Pathol. 2011)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 64412 HGNC: 15808 AceView: ZNF336 Ensembl:ENSG00000125812 euGenes: HUgn64412
    ECgene: GZF1 H-InvDB: GZF1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for GZF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for GZF1 gene:
    Search GeneIP for patents involving GZF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for GZF1   OriGene RNAi products in human, mouse, rat for GZF1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for GZF1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for GZF1  
     OriGene qSTAR qPCR primer pairs in human, mouse for GZF1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for GZF1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for GZF1   OriGene Custom Protein Services for GZF1  

     
     
     Block miRNA regulation of human, mouse, rat GZF1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing GZF1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GZF1 Predesigned siRNA for gene silencing in human, mouse, rat GZF1
     QuantiFast Probe-based Assays in human, mouse, rat GZF1 QuantiTect SYBR Green Assays in human, mouse, rat GZF1
     Custom PCR Arrays for GZF1 Search Chromatin IP Primers for GZF1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GZF1  Search GeneGlobe Interaction Network for GZF1
     Regulatory tfbs in GZF1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for GZF1 GenScript cDNA clones with any tag delivered in your preferred vector for GZF1
     GenScript Custom Assay Services for GZF1 GenScript Custom overexpressing Cell Line Services for GZF1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for GZF1
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     GZF1 antibodies
     GZF1 lysates
     Search for Antibodies for GZF1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for GZF1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for GZF1
     Antibodies for GZF1
     ELISAs for GZF1
     CLIAs for GZF1



     Browse ESI BIO Cell Lines and PureStem Progenitors for GZF1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GZF1
     SwitchGear 3'UTR luciferase reporter plasmids for GZF1
     SwitchGear Promoter luciferase reporter plasmids for GZF1
     ThermoFisher Antibodies for GZF1
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GZF1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GZF1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GZF1
     LSBio Antibodies in human, mouse, rat for GZF1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for GZF1
      Search eBioscience for proteins for GZF1
      Search eBioscience for elisas for GZF1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      GZF1 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4