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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GYPE Gene

protein-coding   GIFtS: 48
GCID: GC04M144792

Glycophorin E (MNS Blood Group)

(Previous name: glycophorin E)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Glycophorin E (MNS Blood Group)1 2
GPE2 3 5
Glycophorin E1
MNS2
MiIX2
glycophorin-E2

External Ids:    HGNC: 47051   Entrez Gene: 29962   Ensembl: ENSG000001974657   OMIM: 1385905   UniProtKB: P154213   

Export aliases for GYPE gene to outside databases

Previous GC identifers: GC04M145588 GC04M145167 GC04M145369 GC04M145149 GC04M145011 GC04M140521


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GYPE Gene:
The protein encoded by this gene is a sialoglycoprotein and a type I membrane protein. It is a member of a gene
family with GPA and GPB genes. This encoded protein might carry the M blood group antigen. GYPA, GYPB, and GYPE
are organized in tandem on chromosome 4. This gene might have derived from an ancestral gene common to the GPB
gene by gene duplication. Two alternatively spliced transcript variants encoding the same protein have been
described for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for GYPE Gene: 
GYPE (glycophorin E (MNS blood group)) is a protein-coding gene. Diseases associated with GYPE include congenital dyserythropoietic anemia type i, and congenital dyserythropoietic anemia. An important paralog of this gene is GYPB.

UniProtKB/Swiss-Prot: GLPE_HUMAN, P15421
Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes

Gene Wiki entry for GYPE Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GYPE gene promoter:
         HTF   FOXD3   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   POU3F2   Nkx5-1   FOXL1   CREB   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGYPE promoter sequence
   Search SABiosciences Chromatin IP Primers for GYPE

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GYPE


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q31.1   Ensembl cytogenetic band:  4q31.21   HGNC cytogenetic band: 4q31.21

GYPE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GYPE gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M144792:  view genomic region     (about GC identifiers)

Start:
144,792,019 bp from pter      End:
144,826,716 bp from pter
Size:
34,698 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GLPE_HUMAN, P15421 (See protein sequence)
Recommended Name: Glycophorin-E precursor  
Size: 78 amino acids; 8463 Da
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: D3DNZ5

Explore the universe of human proteins at neXtProt for GYPE: NX_P15421

Post-translational modifications:

  • UniProtKB: The N-terminal extracellular domain is heavily glycosylated on serine and threonine residues (By similarity)
  • View neXtProt modification sites for NX_P15421

  • GYPE Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins (2 alternative transcripts): 
    NP_002093.2  NP_941391.2  

    ENSEMBL proteins: 
     ENSP00000351430   ENSP00000426746   ENSP00000400698  

    Human Recombinant Protein Products for GYPE: 
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    OriGene Protein Over-expression Lysate for GYPE
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    Novus Biologicals GYPE Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GYPE 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS2295603
    GO:0005887integral to plasma membrane TAS7622054
    GO:0016021integral to membrane ----

    GYPE for ontologies           About GeneDecksing



    GYPE Antibody Products: 
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    Cloud-Clone Corp. ELISAs for GYPE 
    Cloud-Clone Corp. CLIAs for GYPE


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    bloodgroup: Blood group antigens

    1 InterPro protein domain:
     IPR001195 Glycophorin

    Graphical View of Domain Structure for InterPro Entry P15421

    ProtoNet protein and cluster: P15421

    1 Blocks protein domain: IPB001195 Glycophorin A and B

    UniProtKB/Swiss-Prot: GLPE_HUMAN, P15421
    Similarity: Belongs to the glycophorin-A family


    GYPE for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLPE_HUMAN, P15421
    Function: This protein is a minor sialoglycoprotein in human erythrocyte membranes

         Genatlas biochemistry entry for GYPE:
    glycophorin E

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GYPE 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GYPE

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GYPE 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GYPE 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GYPE
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    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of GYPE

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): GYPE (NM_198682)
    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GYPE


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GYPE

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GYPE for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GYPE (GLPE)

    10/32 Novoseek inferred chemical compound relationships for GYPE gene (see all 32)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    1,2-dimyristoylamido-1,2-deoxyphosphatidylcholine 86.9 11 2162203 (5), 2354176 (1)
    sialic acid 77.6 32 9584138 (3), 8595264 (2), 2176879 (2), 1936191 (2) (see all 18)
    dimyristoylphosphatidylcholine 65.8 16 2162203 (4), 1607359 (2), 1632777 (1), 1645183 (1) (see all 6)
    23-diphosphoglycerate 52.8 2 7833349 (1), 2158999 (1)
    galactose 43.5 3 9920164 (1), 12218291 (1), 9501410 (1)
    periodate 43.2 1 2176879 (1)
    phospholipid 34.4 5 8423219 (1), 8130343 (1), 8038182 (1), 2173910 (1) (see all 5)
    dopc 31.9 1 1730024 (1)
    dppc 27.5 2 1607359 (1), 1730024 (1)
    lipid 27 21 1607359 (3), 7607245 (2), 2162203 (2), 1575520 (2) (see all 10)

    Search CenterWatch for drugs/clinical trials and news about GYPE / GLPE

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GYPE gene (2 alternative transcripts): 
    NM_002102.3  NM_198682.2  

    Unigene Cluster for GYPE:

    Glycophorin E (MNS blood group)
    Hs.728753  [show with all ESTs]
    Unigene Representative Sequence: BC064396
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000358615(uc003ijj.3) ENST00000506264 ENST00000437468(uc003ijk.4)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GYPE
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GYPE
    SwitchGear 3'UTR luciferase reporter plasmidGYPE 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GYPE
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GYPE
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): GYPE (NM_198682)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GYPE
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GYPE
    Sirion Biotech Customized lentivirus for stable overexpression of GYPE 
                         Customized lentivirus expression plasmids for stable overexpression of GYPE 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for GYPE
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat GYPE
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GYPE
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GYPE

    Additional mRNA sequence: 

    BC064396.1 M29610.1 

    4 DOTS entries:

    DT.312887  DT.70103461  DT.100839523  DT.414934 

    24/88 AceView cDNA sequences (see all 88):

    NM_198682 H60100 AA262967 H69716 R93593 CR602358 AI288181 N55369 
    CR617175 BC017864 BM978065 AI248923 N70270 BG944586 BV200092 H79337 
    BU623244 H83039 BX325241 N59558 AI240545 M29610 BC069310 H90924 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GYPE expression in normal human tissues (normalized intensities)      GYPE embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    GYPE Expression
    About this image


    GYPE expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             Bone Marrow CD105+ Cells   
             umbilical cord reticulocytes   
     
     Umbilical Cord (Extraembryonic Tissues)
             umbilical cord reticulocytes   
     
     Bone (Muscoskeletal System)
             bone marrow   
     
     Mesoderm (Gastrulation Derivatives)
             Mesoderm-like cells ( Derivation of cardiomyocytes from pluripotent stem cells and...
     
     Oral Cavity (Gastrointestinal Tract)
             saliva   

    Genevestigator expression for GYPE

    SOURCE GeneReport for Unigene cluster: Hs.728753

    UniProtKB/Swiss-Prot: GLPE_HUMAN, P15421
    Tissue specificity: Erythrocytes

        SABiosciences Custom PCR Arrays for GYPE
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GYPE

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and chimp.

    Orthologs for GYPE gene from 1 species (see representative species )    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chimpanzee
    (Pan troglodytes)
    Mammalia GYPE6
    glycophorin E (MNS blood group)
    75(a)
    1 ↔ 1
    4(146644289-146668110)


    ENSEMBL Gene Tree for GYPE (if available)
    TreeFam Gene Tree for GYPE (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GYPE gene
    GYPB2  
    11 SIMAP similar genes for GYPE using alignment to 7 protein entries:     GLPE_HUMAN (see all proteins):
    MiIX    HGpMiV    HGpMiXI    HGpMiVI    GYP(B-A-B)    GYPB
    GYPA    HGpMiX    GPSAT    GPErik    HGPMz

    GYPE for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1024 SNPs in GYPE are shown (see all 1024)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0620064
    ----see VAR_0620062 G E mis40--------
    rs1844103531,2
    --144791653(+) CAATGG/TGTAAA 1 -- int10--------
    rs716124361,2
    C,F--144791679(+) TAGGAG/TAAATT 1 -- int12Minor allele frequency- T:0.50NA 4
    rs1887572551,2
    --144791717(+) GCAAGA/TCTGAA 1 -- int10--------
    rs1450188001,2
    --144791741(+) GTAATC/TAAATC 1 -- int10--------
    rs1149004861,2
    F--144791784(+) TGTCTC/TACATC 1 -- int11Minor allele frequency- T:0.05WA 118
    rs1813130021,2
    --144791816(+) GTGGGC/TTCCCA 1 -- int10--------
    rs1388001001,2
    C--144791835(+) GGAAGC/TTCAGC 1 -- int10--------
    rs1148293351,2
    C,F--144791855(+) TTTGCA/CTGGTA 1 -- int11Minor allele frequency- C:0.02NA 120
    rs346045081,2
    C--144791870(+) CCCCC-/GCCTCG 1 -- int10--------

    HapMap Linkage Disequilibrium report for GYPE (144792019 - 144826716 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/38 variations for GYPE (see all 38):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv980e199CNV Deletion23128226
    dgv978e199CNV Deletion23128226
    nsv436452CNV Deletion17901297
    nsv435790CNV Deletion17901297
    dgv979e199CNV Deletion23128226
    dgv898e201CNV Deletion23290073
    esv2728476CNV Deletion23290073
    esv2728480CNV Deletion23290073
    nsv436411CNV Deletion17901297
    esv2668125CNV Deletion23128226


    Human Gene Mutation Database (HGMD): GYPE

    Locus Specific Mutation Databases (LSDB): GYPE
    Blood Group Antigen Gene Mutation Database (BGMUT) blood group system
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GYPE
    DNA2.0 Custom Variant and Variant Library Synthesis for GYPE

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 138590    OMIM disorders: --

    13 diseases for GYPE:    About MalaCards
    congenital dyserythropoietic anemia type i    congenital dyserythropoietic anemia    autoimmune hemolytic anemia    sickle cell disease
    hemolytic anemia    influenza    malaria    anemia
    vascular disease    multiple myeloma    myeloma    parkinson's disease
    cerebritis

    1 disease from the University of Copenhagen DISEASES database for GYPE:
    Parkinson's disease

    GYPE for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/12 Novoseek inferred disease relationships for GYPE gene (see all 12)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hemolysis 47.3 6 12225367 (1), 8276771 (1), 12181064 (1), 10627480 (1) (see all 5)
    malaria 34.6 2 12949139 (1), 18063920 (1)
    influenza 27.7 6 2069581 (2), 9166405 (1), 10953546 (1), 8499461 (1)
    erythroleukemia 25.5 2 16126901 (1), 8690723 (1)
    somatic mutations 13.2 1 7921055 (1)
    cancer 5.14 1 7653152 (1)
    hematoma 0 2 10916932 (2)
    bleeding 0 9 1920929 (6), 17699396 (1)
    sickle cell disease 0 2 8423219 (1), 8977264 (1)
    vascular diseases 0 2 1312416 (1), 11188894 (1)


    Export disorders for GYPE gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GYPE gene, integrated from 9 sources (see all 166):
    (articles sorted by number of sources associating them with GYPE)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel gene member of the human glycophorin A and B gene family. Molecular cloning and expression. (PubMed id 2390989)1, 2, 9 Vignal A.... Cartron J.-P. (1990)
    2. Identification of a novel human glycophorin, glycophorin E, by isolation of genomic clones and complementary DNA clones utilizing polymerase chain reaction. (PubMed id 2295603)1, 2, 9 Kudo S. and Fukuda M. (1990)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Characterization of glycophorin A transcripts: control by the common erythroid-specific promoter and alternative usage of different polyadenylation signals. (PubMed id 7798177)1, 2 Kudo S.... Fukuda M. (1994)
    5. Promoter sequence and chromosomal organization of the genes encoding glycophorins A, B and E. (PubMed id 2249783)1, 2 Vignal A.... Cartron J.-P. (1990)
    6. Contribution of gene conversion to the retention of the sequence for M blood group type determinant in glycophorin E gene. (PubMed id 7521873)1, 9 Kudo S. and Fukuda M. (1994)
    7. Human erythrocyte glycophorins: protein and gene structure analyses. (PubMed id 1591491)1, 9 Cartron J.P. and Rahuel C. (1992)
    8. Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites. (PubMed id 12949139)1, 9 Wang H.Y.... Wu C.I. (2003)
    9. Molecular analysis of human glycophorin MiIX gene shows a silent segment transfer and untemplated mutation resulting from gene conversion via sequence repeats. (PubMed id 1421409)1, 9 Huang C.H.... Blumenfeld O.O. (1992)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2996 HGNC: 4705 AceView: GYPE Ensembl:ENSG00000197465 euGenes: HUgn2996
    ECgene: GYPE H-InvDB: GYPE

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GYPE Pharmacogenomics, SNPs, Pathways
    dbRBC/BGMUThttp://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=mns

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GYPE gene:
    Search GeneIP for patents involving GYPE

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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