Aliases for GYLTL1B Gene
External Ids for GYLTL1B Gene
Previous GeneCards Identifiers for GYLTL1B Gene
GeneCards Summary for GYLTL1B Gene
GYLTL1B (Glycosyltransferase-Like 1B) is a Protein Coding gene. Diseases associated with GYLTL1B include Interstitial Myocarditis and Ureteral Benign Neoplasm. Among its related pathways are Transport to the Golgi and subsequent modification and O-linked glycosylation. GO annotations related to this gene include transferase activity, transferring glycosyl groups and glucuronosyltransferase activity. An important paralog of this gene is B4GAT1.
UniProtKB/Swiss-Prot for GYLTL1B Gene
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.