Aliases for GYLTL1B Gene
External Ids for GYLTL1B Gene
Previous GeneCards Identifiers for GYLTL1B Gene
GeneCards Summary for GYLTL1B Gene
GYLTL1B (Glycosyltransferase-Like 1B) is a Protein Coding gene. Diseases associated with GYLTL1B include dyscalculia and ureteral benign neoplasm. GO annotations related to this gene include transferase activity, transferring glycosyl groups. An important paralog of this gene is LARGE.
UniProtKB/Swiss-Prot for GYLTL1B Gene
Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide. Has a higher activity toward alpha-dystroglycan than LARGE.