Aliases for GYG2 Gene
External Ids for GYG2 Gene
Previous GeneCards Identifiers for GYG2 Gene
This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glycogenin mainly present in liver; both are involved in blood glucose homeostasis. This gene has a short version on chromosome Y, which is 3' truncated and can not make a functional protein. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]
GeneCards Summary for GYG2 Gene
GYG2 (Glycogenin 2) is a Protein Coding gene. Diseases associated with GYG2 include glycogen storage disease type 0. Among its related pathways are Metabolism and MPS VI - Maroteaux-Lamy syndrome. GO annotations related to this gene include glycogenin glucosyltransferase activity. An important paralog of this gene is GYG1.
UniProtKB/Swiss-Prot for GYG2 Gene
Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase