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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GXYLT1 Gene

protein-coding   GIFtS: 48
GCID: GC12M042476

glucoside xylosyltransferase 1

(Previous name: glycosyltransferase 8 domain containing 3 )
(Previous symbol: GLT8D3)
  Search for GXYLT1
in our new
 Human Malady Compendium 
Biological research products
for GXYLT1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Glucoside Xylosyltransferase 11 2     FLJ431511
GLT8D31 2 3 5     EC 2.4.2.N21
Glycosyltransferase 8 Domain Containing 31 2     EC 2.4.18
Glycosyltransferase 8 Domain-Containing Protein 32 3     

External Ids:    HGNC: 274821   Entrez Gene: 2834642   Ensembl: ENSG000001512337   OMIM: 6133215   UniProtKB: Q4G1483   

Export aliases for GXYLT1 gene to outside databases

Previous GC identifers: GC12M040763 GC12M039502


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GXYLT1:
GXYLT1 is a xylosyltransferase (EC 2.4.2.-) that adds the first xylose to O-glucose-modified residues in the epidermal
growth factor (EGF; MIM 131530) repeats of proteins such as NOTCH1 (MIM 190198) (Sethi et al., 2010 (PubMed
19940119)).(supplied by OMIM, Mar 2010)

UniProtKB/Swiss-Prot: GXLT1_HUMAN, Q4G148
Function: Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular
domain of Notch proteins by catalyzing the addition of xylose




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GXYLT1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for GXYLT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GXYLT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q12   Ensembl cytogenetic band:  12q12   HGNC cytogenetic band: 12q12

GXYLT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GXYLT1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M042476:  view genomic region     (about GC identifiers)

Start:
42,475,647 bp from pter      End:
42,538,681 bp from pter
Size:
63,035 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GXLT1_HUMAN, Q4G148 (See protein sequence)
Recommended Name: Glucoside xylosyltransferase 1  
Size: 440 amino acids; 50567 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Potential)
Secondary accessions: B3KWJ2 Q8IXV1 Q96BH4
Alternative splicing: 2 isoforms:  Q4G148-1   Q4G148-2   

Explore the universe of human proteins at neXtProt for GXYLT1: NX_Q4G148

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q4G148

  • 4/7 DME Specific Peptides for GXYLT1 (Q4G148) (see all 7)
     FRAVYEA  HLAVVACG  NSGVMLMN  SLLYVDTD 

    GXYLT1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001093120.1  NP_775872.1  

    ENSEMBL proteins: 
     ENSP00000381666   ENSP00000280876  
    Reactome Protein details: Q4G148
    Human Recombinant Protein Products: 
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    Uscn Proteins for GXYLT1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane TAS--
    GO:0016021integral to membrane IEA--


    GXYLT1 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for GXYLT1


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GXYLT1 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR002495 Glyco_trans_8

    Graphical View of Domain Structure for InterPro Entry Q4G148

    ProtoNet protein and cluster: Q4G148

    1 Blocks protein family: IPB002495 Glycosyl transferase

    UniProtKB/Swiss-Prot: GXLT1_HUMAN, Q4G148
    Similarity: Belongs to the glycosyltransferase 8 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: GXLT1_HUMAN, Q4G148
    Function: Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular
    domain of Notch proteins by catalyzing the addition of xylose
    Catalytic activity: UDP-D-xylose + beta-D-glucosyl-R = UDP + alpha-D-xylose-(1->3)-beta-D-glucosyl-R

    Enzyme Numbers (IUBMB): EC 2.4.12 EC 2.4.2.n21

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    8/145 QIAGEN miScript miRNA Assays for microRNAs that regulate GXYLT1 (see all 145):
    hsa-miR-579 hsa-miR-3938 hsa-miR-193a-3p hsa-miR-520f hsa-miR-106a hsa-miR-128 hsa-miR-342-3p hsa-miR-208b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GXYLT1

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0035252UDP-xylosyltransferase activity IDA19940119


    GXYLT1 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1MPS IIIC - Sanfilippo syndrome C
    8/15 pathways (see all 15)
    MPS IIIC - Sanfilippo syndrome C1.00
    MPS IIID - Sanfilippo syndrome D1.00
    MPS I - Hurler syndrome1.00
    MPS IX - Natowicz syndrome1.00
    Mucopolysaccharidoses1.00
    MPS II - Hunter syndrome1.00
    MPS IV - Morquio syndrome A1.00
    Glycosaminoglycan metabolism1.00
    2A tetrasaccharide linker sequence is required for GAG synthesis
    A tetrasaccharide linker sequence is required for GAG synthesis1.00
    Chondroitin sulfate/dermatan sulfate metabolism0.54
    3Disease
    Disease1.00
    4Metabolism
    Metabolism1.00
    5Glucuronidation
    Other types of O-glycan biosynthesis0.36

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/19        Reactome Pathways for GXYLT1 (see all 19)
        Chondroitin sulfate/dermatan sulfate metabolism
    MPS VI - Maroteaux-Lamy syndrome
    Metabolism
    Disease
    MPS II - Hunter syndrome


    1         Kegg Pathway  (Kegg details for GXYLT1):
        Other types of O-glycan biosynthesis


    GXYLT1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GXYLT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/25 Interacting proteins for GXYLT1 (Q4G1483 ENSP000003816664) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    FBXO11Q86XK23, ENSP000003238224I2D: score=1 STRING: ENSP00000323822
    RIPK2O433533, ENSP000002207514I2D: score=1 STRING: ENSP00000220751
    ATG5Q9H1Y03, ENSP000003433134I2D: score=1 STRING: ENSP00000343313
    TRAF6Q9Y4K33I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS--
    GO:0016266O-glycan processing IDA19940119
    GO:0030203glycosaminoglycan metabolic process TAS--
    GO:0030204chondroitin sulfate metabolic process TAS--
    GO:0044281small molecule metabolic process TAS--


    GXYLT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GXYLT1
    Search CenterWatch for drugs/clinical trials and news about GXYLT1 / GXLT1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GXYLT1 gene (2 alternative transcripts): 
    NM_001099650.1  NM_173601.1  

    Unigene Cluster for GXYLT1:

    Glucoside xylosyltransferase 1
    Hs.259347  [show with all ESTs]
    Unigene Representative Sequence: NM_173601
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000398675(uc001rms.4 uc001rmt.4) ENST00000280876

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    hsa-miR-579 hsa-miR-3938 hsa-miR-193a-3p hsa-miR-520f hsa-miR-106a hsa-miR-128 hsa-miR-342-3p hsa-miR-208b
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GXYLT1 (see all 7)
    OriGene shRNA RFP: GXYLT1
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    Clone
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    Additional cDNA sequence: 

    AK021504.1 AK021752.1 AK125141.1 AL832209.1 BC015597.2 BC030023.1 BC039145.1 

    5 DOTS entries:

    DT.209030  DT.100657366  DT.97817947  DT.95206892  DT.99928211 

    24/92 AceView cDNA sequences (see all 92):

    AI184457 AK125141 BQ445984 AI189211 AW674965 CB132478 AI741253 BQ446100 
    BG105747 BC015597 CR590862 BG286438 BI560043 AL573187 BF977231 AK021752 
    AL704763 AU119072 AI148343 N56663 AU117406 BG028532 N56651 BX111754 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for GXYLT1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
    SP1:                                                            
    SP2:              -                                             


    ECgene alternative splicing isoforms for GXYLT1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GXYLT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See GXYLT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GXYLT1

    SOURCE GeneReport for Unigene cluster: Hs.259347
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GXYLT1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GXYLT1 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gxylt11 , 5 glucoside xylosyltransferase 11, 5 84.56(n)1
    88.07(a)1
      15 (47.34 cM)5
    2238271  NM_001033275.41  NP_001028447.11 
     932397425 
    chicken
    (Gallus gallus)
    Aves GXYLT11 glucoside xylosyltransferase 1 77.13(n)
    77.21(a)
      417789  NM_001030736.1  NP_001025907.1 
    lizard
    (Anolis carolinensis)
    Reptilia GXYLT16
    --
    82(a)
    1 ↔ 1
    5(55372809-55389837)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.188602 Xenopus laevis transcribed sequences 76.71(n)    CA982017.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gxylt1b1 glucoside xylosyltransferase 1b 58.75(n)
    58.25(a)
      556315  NM_001030099.1  NP_001025270.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG99966
    --
    44(a)
    1 → many
    3R(20898451-20900329)


    ENSEMBL Gene Tree for GXYLT1 (if available)
    TreeFam Gene Tree for GXYLT1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GXYLT1 gene
    GXYLT22  
    1 SIMAP similar gene for GXYLT1 using alignment to 1 protein entry:     GXLT1_HUMAN:
    GXYLT2

    GXYLT1 for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for GXYLT1 (see all 6)
    PGOHUM00000248288 PGOHUM00000239025 PGOHUM00000236080 PGOHUM00000236156 PGOHUM00000236506


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1427 NCBI SNPs in GXYLT1 are shown (see all 1427    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1462822201,2
    --42475170(+) CTAACA/TTCATC 2 -- ds50010--------
    rs111813191,2
    H,--42475205(+) TTTCCG/AAGCAG 2 -- ds50014Minor allele frequency- A:0.00NS EA 420
    rs1442373101,2
    --42475215(+) GCTATC/TCATCA 2 -- ds50010--------
    rs1918937081,2
    --42475317(+) GATAAC/TACACA 2 -- ds50010--------
    rs1828453581,2
    --42475331(+) TGCTGG/TGGCCA 2 -- ds50010--------
    rs1872267111,2
    --42475355(+) ATGGGA/GGCAGG 2 -- ds50010--------
    rs1452417751,2
    --42475360(+) GGCAGA/GTGAAA 2 -- ds50010--------
    rs1487326961,2
    --42475404(+) TTTCAG/TCCTCT 2 -- ds50010--------
    rs79572131,2
    C,F,A,H,--42475438(+) TGTGGT/GCACTT 2 -- ds500111Minor allele frequency- G:0.34NS EA NA CSA WA 784
    rs774480361,2
    F,--42475473(+) ACTCAC/TTTGTT 2 -- ds50011Minor allele frequency- T:0.03WA 118

    HapMap Linkage Disequilibrium report for GXYLT1 (42475647 - 42538681 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for GXYLT1
         1 CNV: 43854

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GXYLT1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GXYLT1 for disorders           About MalaCards

    GXYLT1 for disorders           About GeneDecksing

    OMIM gene information: 613321    OMIM disorders: --


    Export disorders for GXYLT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GXYLT1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with GXYLT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of glycosyltransferase 8 family members as xylosyltransferases acting on o-glucosylated notch epidermal growth factor repeats. (PubMed id 19940119)1, 2, 3 Sethi M.K.... Bakker H. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    6. Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)2 Chen R.... Zou H. (2009)
    7. Large-scale analysis of the human ubiquitin-related p roteome. (PubMed id 16196087)1 Matsumoto M....Nakayama K.I. (2005)
    8. Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)2 Liu T.... Smith R.D. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 283464 HGNC: 27482 AceView: LOC283464 Ensembl:ENSG00000151233 euGenes: HUgn283464
    ECgene: GXYLT1 Kegg: 283464 H-InvDB: GXYLT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GXYLT1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GXYLT1 gene:
    Search GeneIP for patents involving GXYLT1

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