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Aliases for GUSBP1 Gene

Aliases for GUSBP1 Gene

  • Glucuronidase, Beta Pseudogene 1 2 3 5
  • SMA3 4

External Ids for GUSBP1 Gene

Previous GeneCards Identifiers for GUSBP1 Gene

  • GC05P069235
  • GC05U901051
  • GC05P021461

Summaries for GUSBP1 Gene

GeneCards Summary for GUSBP1 Gene

GUSBP1 (Glucuronidase, Beta Pseudogene 1) is a Pseudogene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GUSBP1 Gene

Genomics for GUSBP1 Gene

Regulatory Elements for GUSBP1 Gene

Enhancers for GUSBP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G021151 0.8 ENCODE 14 -189.2 -189170 1.6 TBP PKNOX1 ZBTB21 JUN MAX CEBPG RAD21 HIC1 GATA3 GATA2 GUSBP1 GC05P021189 LOC105374678
GH05G020972 1 Ensembl ENCODE 8.2 -369.1 -369117 1.4 TBP CTCF MAX SIN3A CEBPG RAD21 IRF9 CTBP1 POLR2A ELK1 GUSBP1 GC05M020972 GC05P020958
GH05G021458 1.1 ENCODE 6.3 +117.5 117535 1.0 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CBX5 ZNF207 ZNF143 GUSBP1 GC05M021362 PIR60777
GH05G021613 0.6 ENCODE 8 +272.5 272521 2.2 HDAC2 TEAD4 MAX POU5F1 RBBP5 CHD7 GUSBP1 LOC105374685 PIR32648
GH05G021397 0.3 FANTOM5 8.8 +56.1 56071 0.3 GUSBP1 GC05M021423 GC05M021422
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GUSBP1 on UCSC Golden Path with GeneCards custom track

Promoters for GUSBP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000178813 467 3000 CTCF POLR2A REST

Genomic Location for GUSBP1 Gene

Chromosome:
5
Start:
21,341,833 bp from pter
End:
21,589,372 bp from pter
Size:
247,540 bases
Orientation:
Plus strand

Genomic View for GUSBP1 Gene

Genes around GUSBP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GUSBP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GUSBP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GUSBP1 Gene

Proteins for GUSBP1 Gene

  • Protein details for GUSBP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15486-GUSP1_HUMAN
    Recommended name:
    Putative inactive beta-glucuronidase-like protein SMA3
    Protein Accession:
    Q15486
    Secondary Accessions:
    • A6NLY8
    • A8K1B7
    • Q969T8
    • Q9BUH2

    Protein attributes for GUSBP1 Gene

    Size:
    140 amino acids
    Molecular mass:
    15381 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GUSBP1 Gene

Post-translational modifications for GUSBP1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GUSBP1 Gene

Domains & Families for GUSBP1 Gene

Protein Domains for GUSBP1 Gene

Suggested Antigen Peptide Sequences for GUSBP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q15486

UniProtKB/Swiss-Prot:

GUSP1_HUMAN :
  • Belongs to the glycosyl hydrolase 2 family.
Family:
  • Belongs to the glycosyl hydrolase 2 family.
genes like me logo Genes that share domains with GUSBP1: view

No data available for Gene Families for GUSBP1 Gene

Function for GUSBP1 Gene

Molecular function for GUSBP1 Gene

GENATLAS Biochemistry:
beta-glucuronidase pseudogene 1,including GUSB exons 5,9,10,11 (?same as ZNF4?)
genes like me logo Genes that share phenotypes with GUSBP1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GUSBP1 Gene

Localization for GUSBP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GUSBP1 Gene

Pathways & Interactions for GUSBP1 Gene

SuperPathways for GUSBP1 Gene

No Data Available

Interacting Proteins for GUSBP1 Gene

Gene Ontology (GO) - Biological Process for GUSBP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GUSBP1 Gene

Drugs & Compounds for GUSBP1 Gene

No Compound Related Data Available

Transcripts for GUSBP1 Gene

mRNA/cDNA for GUSBP1 Gene

(1) REFSEQ mRNAs :
(16) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GUSBP1 Gene

Glucuronidase, beta pseudogene 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GUSBP1 Gene

No ASD Table

Relevant External Links for GUSBP1 Gene

GeneLoc Exon Structure for
GUSBP1
ECgene alternative splicing isoforms for
GUSBP1

Expression for GUSBP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GUSBP1 Gene

NURSA nuclear receptor signaling pathways regulating expression of GUSBP1 Gene:

GUSBP1

SOURCE GeneReport for Unigene cluster for GUSBP1 Gene:

Hs.88181

mRNA Expression by UniProt/SwissProt for GUSBP1 Gene:

Q15486-GUSP1_HUMAN
Tissue specificity: Ubiquitous.
genes like me logo Genes that share expression patterns with GUSBP1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GUSBP1 Gene

Orthologs for GUSBP1 Gene

Evolution for GUSBP1 Gene

ENSEMBL:
Gene Tree for GUSBP1 (if available)
TreeFam:
Gene Tree for GUSBP1 (if available)

No data available for Orthologs for GUSBP1 Gene

Paralogs for GUSBP1 Gene

No data available for Paralogs for GUSBP1 Gene

Variants for GUSBP1 Gene

Sequence variations from dbSNP and Humsavar for GUSBP1 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000032991 -- 21,556,031(+) GGGTT(C/T)ATTAA intron-variant
rs1000093044 -- 21,537,283(+) AATAT(C/T)AGTCC intron-variant
rs1000120903 -- 21,546,105(+) TGGCC(A/G)TAAAA intron-variant
rs1000126918 -- 21,468,170(+) CAAGG(G/T)GGGTC intron-variant
rs1000136445 -- 21,549,792(+) AAATA(-/AGTG)AGTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GUSBP1 Gene

Variant ID Type Subtype PubMed ID
dgv3054n106 CNV deletion 24896259
dgv3243e59 CNV duplication 20981092
dgv5603n100 CNV loss 25217958
dgv5604n100 CNV loss 25217958
dgv5605n100 CNV gain 25217958
dgv60n82 CNV duplication 23825009
dgv8n29 CNV gain 16826518
dgv939n67 CNV loss 20364138
dgv9649n54 CNV gain 21841781
dgv9654n54 CNV loss 21841781
dgv9655n54 CNV gain 21841781
esv1123770 CNV deletion 17803354
esv1399308 CNV deletion 17803354
esv2131549 CNV deletion 18987734
esv22726 CNV gain+loss 19812545
esv2479396 CNV gain 19546169
esv2656871 CNV deletion 23128226
esv2662564 CNV deletion 23128226
esv2664380 CNV deletion 23128226
esv2668547 CNV deletion 23128226
esv2669636 CNV deletion 23128226
esv2674883 CNV deletion 23128226
esv2729905 CNV deletion 23290073
esv2729907 CNV deletion 23290073
esv2759331 CNV gain+loss 17122850
esv3380329 OTHER inversion 20981092
esv3384150 CNV insertion 20981092
esv3442861 CNV duplication 20981092
esv3565651 CNV deletion 23714750
esv3565652 CNV deletion 23714750
esv3570044 CNV loss 25503493
esv3575823 CNV gain 25503493
esv3604309 CNV loss 21293372
esv3604313 CNV loss 21293372
esv3604314 CNV loss 21293372
esv3604316 CNV loss 21293372
esv3604317 CNV gain 21293372
esv3894152 CNV gain 25118596
nsv1026463 CNV loss 25217958
nsv1028990 CNV gain 25217958
nsv10680 CNV loss 18304495
nsv10681 CNV gain+loss 18304495
nsv1073446 CNV deletion 25765185
nsv1073447 CNV deletion 25765185
nsv1077452 CNV duplication 25765185
nsv1077453 CNV duplication 25765185
nsv1109683 CNV deletion 24896259
nsv1114661 CNV deletion 24896259
nsv1114662 CNV deletion 24896259
nsv1114663 CNV deletion 24896259
nsv1117544 CNV deletion 24896259
nsv1118728 CNV duplication 24896259
nsv1123923 CNV deletion 24896259
nsv1123924 CNV deletion 24896259
nsv1123925 CNV deletion 24896259
nsv1128149 CNV deletion 24896259
nsv1128150 CNV deletion 24896259
nsv1128908 CNV duplication 24896259
nsv1132604 CNV duplication 24896259
nsv1136976 CNV deletion 24896259
nsv1140521 CNV deletion 24896259
nsv1141476 CNV duplication 24896259
nsv1145816 CNV duplication 26484159
nsv1154130 CNV duplication 26484159
nsv267 CNV insertion 15895083
nsv268 CNV insertion 15895083
nsv428114 CNV gain+loss 18775914
nsv436883 CNV insertion 17901297
nsv4757 CNV deletion 18451855
nsv4758 CNV insertion 18451855
nsv4759 CNV insertion 18451855
nsv509057 CNV insertion 20534489
nsv509059 CNV insertion 20534489
nsv515022 CNV gain 21397061
nsv597463 CNV gain+loss 21841781
nsv597492 CNV gain 21841781
nsv7369 OTHER inversion 18451855
nsv821602 CNV duplication 20802225
nsv830229 CNV gain 17160897
nsv950660 CNV duplication 24416366
nsv950661 CNV duplication 24416366
nsv964820 CNV duplication 23825009
nsv968148 CNV duplication 23825009
nsv968149 CNV duplication 23825009
nsv968151 CNV duplication 23825009
nsv968298 CNV duplication 23825009
nsv969041 CNV duplication 23825009
nsv980614 CNV duplication 23825009
nsv980615 CNV duplication 23825009
nsv980616 CNV duplication 23825009
nsv980617 CNV duplication 23825009
nsv980784 CNV duplication 23825009

Relevant External Links for GUSBP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GUSBP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for GUSBP1 Gene

Disorders for GUSBP1 Gene

Relevant External Links for GUSBP1

Genetic Association Database (GAD)
GUSBP1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GUSBP1

No disorders were found for GUSBP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GUSBP1 Gene

Publications for GUSBP1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 3 4 64
  3. Localization by fluorescence in situ hybridization of the human functional beta-glucuronidase gene (GUSB) to 7q11.21 --> q11.22 and two pseudogenes to 5p13 and 5q13. (PMID: 8565635) Speleman F. … Lissens W. (Cytogenet. Cell Genet. 1996) 2 3 64
  4. Complex repetitive arrangements of gene sequence in the candidate region of the spinal muscular atropy gene in 5q13. (PMID: 7977382) Theodosiou A.M. … Davies K.E. (Am. J. Hum. Genet. 1994) 3 4 64
  5. Genome-wide association analysis implicates the involvement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. (PMID: 22491018) Wang J. … Platt A. (Pharmacogenomics J. 2013) 46 64

Products for GUSBP1 Gene

Sources for GUSBP1 Gene

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