Aliases for GULP1 Gene
External Ids for GULP1 Gene
Previous GeneCards Identifiers for GULP1 Gene
The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]
GeneCards Summary for GULP1 Gene
GULP1 (GULP, Engulfment Adaptor PTB Domain Containing 1) is a Protein Coding gene. Among its related pathways are Arf6 signaling events. GO annotations related to this gene include signal transducer activity. An important paralog of this gene is NUMB.
UniProtKB/Swiss-Prot for GULP1 Gene
May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.