Aliases for GUK1 Gene
External Ids for GUK1 Gene
Previous GeneCards Identifiers for GUK1 Gene
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for GUK1 Gene
GUK1 (Guanylate Kinase 1) is a Protein Coding gene. Diseases associated with GUK1 include Retinitis Pigmentosa. Among its related pathways are Abacavir Pathway, Pharmacokinetics/Pharmacodynamics and purine nucleotides de novo biosynthesis. GO annotations related to this gene include guanylate kinase activity. An important paralog of this gene is LRRC23.
UniProtKB/Swiss-Prot for GUK1 Gene
Essential for recycling GMP and indirectly, cGMP.