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Aliases for GUCD1 Gene

Aliases for GUCD1 Gene

  • Guanylyl Cyclase Domain Containing 1 2 3
  • Guanylyl Cyclase Domain-Containing Protein 1 3 4
  • C22orf13 3 4
  • LLN4 3 4
  • CG13760 Gene Product [Drosophila Melanogaster] Homolog 3
  • Chromosome 22 Open Reading Frame 13 2
  • Protein GUCD1 3
  • Protein LLN4 4

External Ids for GUCD1 Gene

Previous Symbols for GUCD1 Gene

  • C22orf13

Summaries for GUCD1 Gene

GeneCards Summary for GUCD1 Gene

GUCD1 (Guanylyl Cyclase Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GUCD1 Gene

Genomics for GUCD1 Gene

Genomic Location for GUCD1 Gene

Start:
24,540,423 bp from pter
End:
24,555,935 bp from pter
Size:
15,513 bases
Orientation:
Minus strand

Genomic View for GUCD1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GUCD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GUCD1 Gene

No data available for Regulatory Elements for GUCD1 Gene

Proteins for GUCD1 Gene

  • Protein details for GUCD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96NT3-GUCD1_HUMAN
    Recommended name:
    Protein GUCD1
    Protein Accession:
    Q96NT3
    Secondary Accessions:
    • B5MCB8
    • B5MCL7
    • Q96Q79
    • Q9BU32

    Protein attributes for GUCD1 Gene

    Size:
    240 amino acids
    Molecular mass:
    27207 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB68411.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for GUCD1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GUCD1 Gene

Proteomics data for GUCD1 Gene at MOPED

Post-translational modifications for GUCD1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GUCD1 Gene

Domains for GUCD1 Gene

Protein Domains for GUCD1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with GUCD1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for GUCD1 Gene

Function for GUCD1 Gene

Gene Ontology (GO) - Molecular Function for GUCD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GUCD1: view

Phenotypes for GUCD1 Gene

genes like me logo Genes that share phenotypes with GUCD1: view

miRNA for GUCD1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for GUCD1 Gene

Localization for GUCD1 Gene

No data available for Gene Ontology (GO) - Cellular Components for GUCD1 Gene

Pathways for GUCD1 Gene

SuperPathways for GUCD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GUCD1 Gene

None

No data available for Pathways by source for GUCD1 Gene

Transcripts for GUCD1 Gene

Unigene Clusters for GUCD1 Gene

Guanylyl cyclase domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GUCD1 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d
SP1: - -
SP2: - - -
SP3: - - - -
SP4: - - - -
SP5: - -
SP6:
SP7:

Relevant External Links for GUCD1 Gene

GeneLoc Exon Structure for
GUCD1
ECgene alternative splicing isoforms for
GUCD1

Expression for GUCD1 Gene

mRNA expression in normal human tissues for GUCD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for GUCD1 Gene

SOURCE GeneReport for Unigene cluster for GUCD1 Gene Hs.9850

genes like me logo Genes that share expressions with GUCD1: view

Orthologs for GUCD1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GUCD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C22H22orf13 36
  • 99.44 (n)
  • 99.32 (a)
GUCD1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C17H22orf13 36
  • 88.21 (n)
  • 89.08 (a)
C17H22orf13 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 89 (a)
OneToMany
-- 37
  • 76 (a)
OneToMany
C26H22orf13 36
  • 92.29 (n)
  • 93.01 (a)
mouse
(Mus musculus)
Mammalia Gucd1 36
  • 90.98 (n)
  • 94.76 (a)
Gucd1 16
Gucd1 37
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GUCD1 37
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GUCD1 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gucd1 36
  • 89.52 (n)
  • 93.45 (a)
chicken
(Gallus gallus)
Aves C15H22ORF13 36
  • 72.24 (n)
  • 71.75 (a)
GUCD1 37
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GUCD1 37
  • 73 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.7463 36
tropical clawed frog
(Silurana tropicalis)
Amphibia gucd1 36
  • 73.93 (n)
  • 73.33 (a)
Str.6101 36
zebrafish
(Danio rerio)
Actinopterygii gucd1 36
  • 69.49 (n)
  • 69.64 (a)
gucd1 37
  • 69 (a)
OneToOne
wufi27d12 36
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011198 36
  • 47.71 (n)
  • 38.86 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13760 36
  • 55.94 (n)
  • 43.56 (a)
CG13760 37
  • 38 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons GC1 36
  • 45.98 (n)
  • 35.71 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 38 (a)
OneToOne
Species with no ortholog for GUCD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GUCD1 Gene

ENSEMBL:
Gene Tree for GUCD1 (if available)
TreeFam:
Gene Tree for GUCD1 (if available)

Paralogs for GUCD1 Gene

Selected SIMAP similar genes for GUCD1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GUCD1: view

No data available for Paralogs for GUCD1 Gene

Variants for GUCD1 Gene

Sequence variations from dbSNP and Humsavar for GUCD1 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs9704 -- 24,541,002(-) AAAAT(C/T)GTTAG utr-variant-3-prime, nc-transcript-variant
rs11259 -- 24,540,694(+) ATGCA(A/G)CACAG utr-variant-3-prime, nc-transcript-variant
rs730373 -- 24,544,021(-) GCTGG(G/T)GAACT missense, reference, intron-variant
rs738820 -- 24,551,484(+) TGGCC(C/T)GCCAG intron-variant
rs743366 -- 24,543,321(+) CAGAG(A/C)GGGGC intron-variant

Relevant External Links for GUCD1 Gene

HapMap Linkage Disequilibrium report
GUCD1

No data available for Structural Variations from Database of Genomic Variants (DGV) for GUCD1 Gene

Disorders for GUCD1 Gene

No disorders were found for GUCD1 Gene.

No data available for UniProtKB/Swiss-Prot for GUCD1 Gene

Publications for GUCD1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for GUCD1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate GUCD1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for GUCD1
    • Block miRNA regulation of GUCD1 using miScript Target Protectors

    Sources for GUCD1 Gene

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