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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GTPBP1 Gene

protein-coding   GIFtS: 52
GCID: GC22P039101

GTP Binding Protein 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
GTP Binding Protein 11 2
GP12 3 5
GP-12 3
G-Protein 12 3
HSPC0182
GTP-Binding Protein 12

External Ids:    HGNC: 46691   Entrez Gene: 95672   Ensembl: ENSG000001002267   OMIM: 6022455   UniProtKB: O001783   

Export aliases for GTPBP1 gene to outside databases

Previous GC identifers: GC22P035716 GC22P037345 GC22P037426 GC22P022067


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GTPBP1 Gene:
This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of
GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for
that protein had no observable phenotype. (provided by RefSeq, Jul 2008)

GeneCards Summary for GTPBP1 Gene: 
GTPBP1 (GTP binding protein 1) is a protein-coding gene. Diseases associated with GTPBP1 include lassa fever, and lymphocytic choriomeningitis. GO annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GTPBP2.

UniProtKB/Swiss-Prot: GTPB1_HUMAN, O00178
Function: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability.
Binds GTP and has GTPase activity (By similarity)

Gene Wiki entry for GTPBP1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NT_011520.12  NC_018933.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GTPBP1 gene promoter:
         USF1   AML1a   FOXD1   Evi-1   N-Myc   POU2F1   POU2F1a   USF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGTPBP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for GTPBP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTPBP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.1   Ensembl cytogenetic band:  22q13.1   HGNC cytogenetic band: 22q13.1

GTPBP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTPBP1 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P039101:  view genomic region     (about GC identifiers)

Start:
39,101,728 bp from pter      End:
39,134,304 bp from pter
Size:
32,577 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GTPB1_HUMAN, O00178 (See protein sequence)
Recommended Name: GTP-binding protein 1  
Size: 669 amino acids; 72454 Da
Subunit: Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a
complex with AANAT mRNA, but does not bind mRNA by itself (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=AAB51273.1; Type=Erroneous initiation; Sequence=CAG30387.1; Type=Erroneous initiation;
Secondary accessions: Q6IC67

Explore the universe of human proteins at neXtProt for GTPBP1: NX_O00178

Explore proteomics data for GTPBP1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O00178

  • GTPBP1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GTPBP1 Protein Expression
    REFSEQ proteins: NP_004277.2  
    ENSEMBL proteins: 
     ENSP00000216044   ENSP00000442881   ENSP00000397891   ENSP00000439505   ENSP00000442628  
     ENSP00000388147   ENSP00000442394   ENSP00000445610   ENSP00000437430  

    Human Recombinant Protein Products for GTPBP1: 
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    Novus Biologicals GTPBP1 Proteins
    Novus Biologicals GTPBP1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GTPBP1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000177cytoplasmic exosome (RNase complex) ISS--
    GO:0005829cytosol ISS--

    GTPBP1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for GTPBP1 
    Cloud-Clone Corp. CLIAs for GTPBP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR000795 EF_GTP-bd_dom
     IPR004160 Transl_elong_EFTu/EF1A_C
     IPR004161 Transl_elong_EFTu/EF1A_2
     IPR009000 Transl_elong_init/rib_B-barrel
     IPR027417 P-loop_NTPase

    Graphical View of Domain Structure for InterPro Entry O00178

    ProtoNet protein and cluster: O00178

    1 Blocks protein domain: IPB004160 Elongation factor Tu

    UniProtKB/Swiss-Prot: GTPB1_HUMAN, O00178
    Similarity: Belongs to the GTPBP1 GTP-binding protein family


    GTPBP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GTPB1_HUMAN, O00178
    Function: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability.
    Binds GTP and has GTPase activity (By similarity)

         Genatlas biochemistry entry for GTPBP1:
    GTP binding protein 1

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ISS--
    GO:0005525GTP binding IEA--
         
    GTPBP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Gtpbp1):
     normal 

    GTPBP1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Gtpbp1tm1Ynim for GTPBP1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GTPBP1 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GTPBP1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GTPBP1 

    miRNA
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    8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate GTPBP1 (see all 53):
    hsa-miR-4254 hsa-miR-15a hsa-miR-346 hsa-miR-219-5p hsa-miR-374a hsa-miR-3921 hsa-miR-890 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidGTPBP1 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTPBP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GTPBP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 23)

    5/574 Interacting proteins for GTPBP1 (O001782, 3 ENSP000002160444) via UniProtKB, MINT, STRING, and/or I2D (see all 574)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRP1Q079543, ENSP000002430774I2D: score=2 STRING: ENSP00000243077
    EXOSC10Q017802, ENSP000003661354MINT-7947479 STRING: ENSP00000366135
    IRF5Q135683, ENSP000003497704I2D: score=1 STRING: ENSP00000349770
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    SRP72O760942, ENSP000003421814MINT-7947479 STRING: ENSP00000342181
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ISS--
    GO:0006955immune response TAS9070279
    GO:0007165signal transduction TAS9070279
    GO:0061014positive regulation of mRNA catabolic process ISS--

    GTPBP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTPBP1 (GTPB1)

    1 HMDB Compound for GTPBP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Search CenterWatch for drugs/clinical trials and news about GTPBP1 / GTPB1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GTPBP1 gene: 
    NM_004286.4  

    Unigene Cluster for GTPBP1:

    GTP binding protein 1
    Hs.276925  [show with all ESTs]
    Unigene Representative Sequence: NM_004286
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000216044(uc003awg.3) ENST00000484657 ENST00000418601 ENST00000461428
    ENST00000488787 ENST00000470836 ENST00000460605 ENST00000475959 ENST00000458073
    ENST00000462332 ENST00000484971 ENST00000487538 ENST00000489527
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GTPBP1
    8/53 QIAGEN miScript miRNA Assays for microRNAs that regulate GTPBP1 (see all 53):
    hsa-miR-4254 hsa-miR-15a hsa-miR-346 hsa-miR-219-5p hsa-miR-374a hsa-miR-3921 hsa-miR-890 hsa-miR-9
    SwitchGear 3'UTR luciferase reporter plasmidGTPBP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GTPBP1
    Clone
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    OriGene clones in human, mouse for GTPBP1 (see all 8)
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GTPBP1
    Sirion Biotech Customized lentivirus for stable overexpression of GTPBP1 
                         Customized lentivirus expression plasmids for stable overexpression of GTPBP1 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GTPBP1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GTPBP1

    Additional mRNA sequence: 

    AF077204.1 AF370385.1 AK095950.1 AK096647.1 AK315704.1 BC001701.2 BC014075.1 BC016030.1 
    BC046350.2 CR456501.1 U87964.1 

    12 DOTS entries:

    DT.444999  DT.97786830  DT.100777046  DT.75102066  DT.95169389  DT.100044139  DT.100673538  DT.91660591 
    DT.120664800  DT.120664907  DT.91750341  DT.95111634 

    24/240 AceView cDNA sequences (see all 240):

    BQ644109 CA443401 CR456501 BM717014 BF001482 CD675613 AI620690 BM477051 
    BU501669 BE295515 BC016030 BM700725 BU178914 BF058481 BF514508 BM561761 
    BC046350 BQ773591 BQ023808 AA026413 AK095950 BU733154 U87964 BM708386 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for GTPBP1 (see all 7)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15
    SP1:                    -     -     -                                                     -                                   -               
    SP2:        -     -     -     -     -                                                                                                         
    SP3:                    -     -     -     -                                                                                                   
    SP4:                                                                                                                                          
    SP5:                                -                                                                                                         


    ECgene alternative splicing isoforms for GTPBP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GTPBP1 expression in normal human tissues (normalized intensities)      GTPBP1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTACTGTG
    GTPBP1 Expression
    About this image


    GTPBP1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
             Muscle Progenitor Cells Mandibular Arch Muscles

    See GTPBP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GTPBP1

    SOURCE GeneReport for Unigene cluster: Hs.276925
        SABiosciences Custom PCR Arrays for GTPBP1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTPBP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GTPBP1 gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gtpbp11 , 5 GTP binding protein 11, 5 90.72(n)1
    97.31(a)1
      15 (37.85 cM)5
    149041  NM_013818.21  NP_038846.21 
     796908965 
    chicken
    (Gallus gallus)
    Aves GTPBP11 GTP binding protein 1 81.53(n)
    92.47(a)
      418022  NM_001201447.1  NP_001188376.1 
    lizard
    (Anolis carolinensis)
    Reptilia GTPBP16
    Uncharacterized protein
    88(a)
    1 ↔ 1
    5(24171347-24196383)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.147242 Xenopus laevis transcribed sequence with weak similarity more 80.39(n)    AW639346.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb36e062 Danio rerio cDNA clone MGC66228 IMAGE3817707, complete more 78.86(n)    BC057488.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Dgp-11 , 3 GTP binding3
    CG5729-PA1
    71(a)3
    63.64(n)1
    66.72(a)1
      55B113
    370801  NM_137458.21  NP_611302.11 
    worm
    (Caenorhabditis elegans)
    Secernentea cgp-11 Protein CGP-1 55.02(n)
    57.06(a)
      178540  NM_070736.6  NP_503137.1 


    ENSEMBL Gene Tree for GTPBP1 (if available)
    TreeFam Gene Tree for GTPBP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GTPBP1 gene
    GTPBP22  
    1 SIMAP similar gene for GTPBP1 using alignment to 9 protein entries:     GTPB1_HUMAN (see all proteins):
    GTPBP2

    GTPBP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/623 SNPs in GTPBP1 are shown (see all 623)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1845910711,2
    --39099876(+) GGTCTC/TGAACT 1 -- us2k10--------
    rs1890993861,2
    --39099897(+) GGTGAA/TCTGCC 1 -- us2k10--------
    rs1454909501,2
    --39099966(+) TGAACG/TCTTTG 1 -- us2k10--------
    rs1814600931,2
    --39100066(+) CAACAC/TCTCTG 1 -- us2k10--------
    rs1116836431,2
    C--39100119(+) GTGCTG/TCAGGG 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs57572511,2
    C,F,A,H--39100128(+) gggacA/Gccagc 1 -- us2k1 tfbs314Minor allele frequency- G:0.25NS WA NA CSA EA 1322
    rs1864019691,2
    --39100144(+) GTCCTC/GTAGTT 1 -- us2k10--------
    rs1893843471,2
    --39100158(+) TTCAAA/TTCGTC 1 -- us2k10--------
    rs60012041,2
    C,F,A,H--39100239(+) tccttT/Cagaag 1 -- us2k1 trp311Minor allele frequency- C:0.47NS EA WA NA 784
    rs60012051,2
    C--39100264(+) AGGCCT/ACCAGT 1 -- us2k14Minor allele frequency- A:0.30NA WA EA 360

    HapMap Linkage Disequilibrium report for GTPBP1 (39101728 - 39134304 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for GTPBP1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv991516CNV Deletion20482838
    nsv915067CNV Loss21882294
    nsv915068CNV Loss21882294
    dgv769n67CNV Gain20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602245    OMIM disorders: --

    5 diseases for GTPBP1:    About MalaCards
    lassa fever    lymphocytic choriomeningitis    fragile x syndrome    antiphospholipid syndrome
    adenoma


    GTPBP1 for disorders           About GeneDecksing


    Export disorders for GTPBP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GTPBP1 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with GTPBP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of human and mouse GP-1, a putative member of a novel G-protein family. (PubMed id 9070279)1, 2, 3, 9 Senju S. and Nishimura Y. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
    4. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I....O'Brien K.P. (1999)
    5. Mouse and human GTPBP2, newly identified members of the GP-1 family of GTPase. (PubMed id 10833435)1, 9 Kudo H.... Nishimura Y. (2000)
    6. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
    7. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    8. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9567 HGNC: 4669 AceView: GTPBP1 Ensembl:ENSG00000100226 euGenes: HUgn9567
    ECgene: GTPBP1 H-InvDB: GTPBP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GTPBP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GTPBP1 gene:
    Search GeneIP for patents involving GTPBP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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