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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GTF3C4 Gene

protein-coding   GIFtS: 53
GCID: GC09P135545

General Transcription Factor IIIC, Polypeptide 4, 90kDa

(Previous names: general transcription factor IIIC, polypeptide 4 (90kD))
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Aliases
for GTF3C4 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
Aliases
General Transcription Factor IIIC, Polypeptide 4, 90kDa1 2     KAT122
Transcription Factor IIIC 90 KDa Subunit2 3     TFIII902
Transcription Factor IIIC Subunit Delta2 3     TFIIIC2902
TF3C-delta2 3     TFIIICDELTA2
TFIIIC902 3     General Transcription Factor 3C 42
TFIIIC 90 KDa Subunit2 3     General Transcription Factor 3C Polypeptide 42
General Transcription Factor IIIC, Polypeptide 4 (90kD)1     EC 2.3.1.483

External Ids:    HGNC: 46671   Entrez Gene: 93292   Ensembl: ENSG000001254847   OMIM: 6048925   UniProtKB: Q9UKN83   

Export aliases for GTF3C4 gene to outside databases

Previous GC identifers: GC09P126570 GC09P127102 GC09P128899 GC09P130821 GC09P132574 GC09P134535 GC09P105039


Summaries
for GTF3C4 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
GeneCards Summary for GTF3C4 Gene: 
GTF3C4 (general transcription factor IIIC, polypeptide 4, 90kDa) is a protein-coding gene. Among its related super-pathways are RNA Polymerase III Transcription Initiation and Transcription of tRNA. GO annotations related to this gene include histone acetyltransferase activity and enzyme activator activity.

UniProtKB/Swiss-Prot: TF3C4_HUMAN, Q9UKN8
Function: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S
RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase
activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the
recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be
localized close to the A box

Gene Wiki entry for GTF3C4 Gene


Genomic Views
for GTF3C4 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.2  NT_035014.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GTF3C4 gene promoter:
         Nkx2-2   YY1   C/EBPalpha   E47   E2F   E2F-1   POU2F1   POU2F1a   Hand1   ZIC2/Zic2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GTF3C4 promoter sequence
   Search SABiosciences Chromatin IP Primers for GTF3C4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTF3C4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13   Ensembl cytogenetic band:  9q34.13   HGNC cytogenetic band: 9q34.3

GTF3C4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTF3C4 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P135545:  view genomic region     (about GC identifiers)

Start:
 135,545,422 bp from pter      End:
 135,570,342 bp from pter
Size:
 24,921 bases      Orientation:
 plus strand

Proteins
for GTF3C4 gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB/Swiss-Prot: TF3C4_HUMAN, Q9UKN8 (See protein sequence)
Recommended Name: General transcription factor 3C polypeptide 4  
Size: 822 amino acids; 91982 Da
Subunit: Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5
and GTF3C6. Interacts with BRF1, GTF3C1, GTF3C2, GTF3C5, GTF3C6, POLR3C and POLR3F
Subcellular location: Nucleus
Sequence caution: Sequence=AAH11619.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence;
Secondary accessions: Q5VZJ7

Explore the universe of human proteins at neXtProt for GTF3C4: NX_Q9UKN8

Explore proteomics data for GTF3C4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UKN8

    • GTF3C4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GTF3C4 Protein Expression
    REFSEQ proteins: NP_036336.2  
    ENSEMBL proteins: 
     ENSP00000431378   ENSP00000361219  
    Reactome Protein details: Q9UKN8
    Human Recombinant Protein Products for GTF3C4: 
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    Novus Biologicals GTF3C4 Protein
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GTF3C4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000127transcription factor TFIIIC complex IDA17409385
    GO:0005654nucleoplasm TAS--

    GTF3C4 for ontologies           About GeneDecksing



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    ThermoFisher Antibody for GTF3C4
    LSBio Antibodies in human, mouse, rat for GTF3C4 

    Assay Products for GTF3C4: 
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    Cloud-Clone Corp. ELISAs for GTF3C4 
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    Protein Domains /
    Families
    for GTF3C4 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		 HGNC Gene Families: 
    KAT: Chromatin-modifying enzymes / K-acetyltransferases
    GTF: General transcription factors

    2 InterPro protein domains:
     IPR024764 TFIIIC_Znf
     IPR024761 TFIIIC_delta_N

    Graphical View of Domain Structure for InterPro Entry Q9UKN8

    ProtoNet protein and cluster: Q9UKN8

    UniProtKB/Swiss-Prot: TF3C4_HUMAN, Q9UKN8
    Similarity: Belongs to the TFIIIC subunit 4 family


    GTF3C4 for domains           About GeneDecksing


    Function
    for GTF3C4 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TF3C4_HUMAN, Q9UKN8
    Function: Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S
    RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase
    activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the
    recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be
    localized close to the A box
    Catalytic activity: Acetyl-CoA + [histone] = CoA + acetyl-[histone]

         Enzyme Number (IUBMB): EC 2.3.1.481

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677contributes to DNA binding IC17409385
    GO:0004402histone acetyltransferase activity IEA--
    GO:0005515protein binding IPI17409385
    GO:0008047enzyme activator activity TAS10523658
         
    GTF3C4 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GTF3C4:
     Increased S DNA content  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GTF3C4 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GTF3C4 
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    miRNA
    Products:            		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GTF3C4
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate GTF3C4:
    hsa-miR-4303 hsa-miR-505 hsa-miR-4307 hsa-miR-3155 hsa-miR-484 hsa-miR-141* hsa-miR-642b hsa-miR-3155b
    SwitchGear 3'UTR luciferase reporter plasmid: GTF3C4 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of GTF3C4

    Clone
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    Cell Line
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    In Situ Assay
    Products:       
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    Pathways & Interactions
    for GTF3C4 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GTF3C4 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase III Transcription Initiation
    		RNA Polymerase III Transcription Initiation0.80
    		RNA Polymerase III Transcription Initiation From Type 1 Promoter0.77
    		RNA Polymerase III Transcription0.80
    		RNA Polymerase III Transcription Initiation From Type 2 Promoter0.74
    		RNA Polymerase III Abortive And Retractive Initiation0.80
    		RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    2Assembly of RNA Polymerase-III Initiation Complex
    		Assembly of RNA Polymerase-III Initiation Complex0.83
    		Transcription of tRNA0.83
    3Transcription
    		Transcription0.69
    4Generic Transcription Pathway
    		Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GTF3C4
        Transcription of tRNA
    Assembly of RNA Polymerase-III Initiation Complex

    5/8        Reactome Pathways for GTF3C4 (see all 8)
        RNA Polymerase III Transcription Initiation
    Transcription
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
    RNA Polymerase III Abortive And Retractive Initiation
    RNA Polymerase III Transcription Initiation From Type 1 Promoter



    GTF3C4 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GTF3C4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/691 Interacting proteins for GTF3C4 (Q9UKN82, 3 ENSP000003612194) via UniProtKB, MINT, STRING, and/or I2D (see all 691)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTF3C3Q9Y5Q92, 3, ENSP000002639564MINT-7945693 I2D: score=1 STRING: ENSP00000263956
    HIST2H3AQ71DI33, ENSP000003854794I2D: score=2 STRING: ENSP00000385479
    GTF3C1Q127892, 3, ENSP000003485104MINT-7945693 MINT-6488791 I2D: score=2 STRING: ENSP00000348510
    HIST2H3DQ71DI33, ENSP000003332774I2D: score=2 STRING: ENSP00000333277
    HIST2H3CQ71DI33I2D: score=2 
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IC17409385
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0006384transcription initiation from RNA polymerase III promoter TAS10523658
    GO:0010467gene expression TAS--
    GO:0016573histone acetylation TAS10523658

    GTF3C4 for ontologies           About GeneDecksing



    Drugs & Compounds
    for GTF3C4 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTF3C4 (TF3C4)

    2 HMDB Compounds for GTF3C4    About this table
    CompoundSynonyms CAS #PubMed Ids
    Acetyl-CoAS-Acetyl coenzyme A (see all 13)72-89-9--
    Coenzyme AAcetoacetyl coenzyme A sodium salt (see all 21)85-61-0--

    Search CenterWatch for drugs/clinical trials and news about GTF3C4 / TF3C4

    Transcripts
    for GTF3C4 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for GTF3C4 gene: 
    NM_012204.2  

    Unigene Cluster for GTF3C4:

    General transcription factor IIIC, polypeptide 4, 90kDa
    Hs.656646  [show with all ESTs]
    Unigene Representative Sequence: NM_012204
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483873 ENST00000372146(uc010mzv.3 uc010mzw.3)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate GTF3C4:
    hsa-miR-4303 hsa-miR-505 hsa-miR-4307 hsa-miR-3155 hsa-miR-484 hsa-miR-141* hsa-miR-642b hsa-miR-3155b
    SwitchGear 3'UTR luciferase reporter plasmid: GTF3C4 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF086460.1 AF142328.1 AJ420451.1 AK024655.1 AK027509.1 AK126436.1 BC011619.2 BC022787.1 
    BC060821.1 BC094774.1 BC104755.1 BC112245.1 

    9 DOTS entries:

    DT.101978566  DT.100707633  DT.97841365  DT.95259571  DT.97816401  DT.40111373  DT.91717779  DT.95225516 
    DT.97803439 

    24/202 AceView cDNA sequences (see all 202):

    BQ004332 AK027509 BM992078 BM475335 Z44435 AA974491 AA587653 BC022787 
    BQ428209 H88620 AI078049 AA732790 BU632842 AW450958 AV726942 AW193285 
    BC011619 BM974523 AF086460 AI184450 BQ002223 BE019328 AI457895 AW043778 

    GeneLoc Exon Structure


    Expression
    for GTF3C4 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GTF3C4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGTAACAGAA
    GTF3C4 Expression
    About this image


    See GTF3C4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GTF3C4

    SOURCE GeneReport for Unigene cluster: Hs.656646
        SABiosciences Custom PCR Arrays for GTF3C4
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    In Situ
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         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTF3C4

    Orthologs
    for GTF3C4 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for GTF3C4 gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Gtf3c41 , 5 general transcription factor IIIC, polypeptide 41, 5 87.6(n)1
    93.76(a)1    		   2 (19.38 cM)5
    2692521  NM_172977.31  NP_766565.21 
     288223055 
    chicken
    (Gallus gallus)    		 Aves GTF3C41 general transcription factor IIIC, polypeptide 4, 9 more 79.07(n)
    86.48(a)    		   417167  XM_415450.3  XP_415450.3 
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.145762 Xenopus laevis transcribed sequence with moderate similarity more 73.96(n)    BJ060086.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.102452 Transcribed sequence with weak similarity to protein more 72.79(n)    57065365 


    ENSEMBL Gene Tree for GTF3C4 (if available)
    TreeFam Gene Tree for GTF3C4 (if available)

    Paralogs
    for GTF3C4 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for GTF3C4 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/405 SNPs in GTF3C4 are shown (see all 405)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 9 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    VAR_0470984
    		----see VAR_0470982 H R mis40--------
    rs4154101,2
    		C,F,O,A,H--135547839(+) CCAGGC/TGGCAG 1 -- int120Minor allele frequency- N:0.00EA NA NS WA CSA 1418
    rs722262851,2
    		C--135547891(+) GAACA-/TAAT  
                TAATT     		1 -- int10--------
    rs592718091,2
    		C--135547893(+) AATTA-/ATTA  
                TTGTT     		1 -- int10--------
    rs2013761621,2
    		C--135547893(+) ACATAA/CTTAAT 1 -- int10--------
    rs1837955071,2
    		--135547925(+) TCAGTA/CCATGA 1 -- int10--------
    rs1879186621,2
    		--135548029(+) GAAGTA/CTTTAA 1 -- int10--------
    rs1913042551,2
    		--135548101(+) AGAGGC/TAAGAA 1 -- int10--------
    rs1826828351,2
    		C--135548333(+) TTGGGA/GGGCCG 1 -- int10--------
    rs802971521,2
    		C--135548551(+) GGCGAA/CAGAGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for GTF3C4 (135545422 - 135570342 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GTF3C4: --
    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for GTF3C4 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    GTF3C4 for disorders           About MalaCards
    OMIM gene information: 604892    OMIM disorders: --


    GTF3C4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GTF3C4
    Human Genome Epidemiology (HuGE) Navigator: GTF3C4 (1 document)

    Export disorders for GTF3C4 gene to outside databases

    Publications
    for GTF3C4 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GTF3C4 gene, integrated from 9 sources (see all 40):
    (articles sorted by number of sources associating them with GTF3C4)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity. (PubMed id 10523658)1, 2, 3 Hsieh Y.-J.... Roeder R.G. (1999)
    2. Identification, molecular cloning, and characterization of the sixth subunit of human transcription factor TFIIIC. (PubMed id 17409385)1, 2 Dumay-Odelot H.... Teichmann M. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity. (PubMed id 23349634)1 Cloutier P.... Coulombe B. (2013)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PubMed id 22751105)1 Chu L....Tomasson M.H. (2012)
    9. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    10. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)

    External Searches for GTF3C4 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing GTF3C4 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9329 HGNC: 4667 AceView: GTF3C4 Ensembl:ENSG00000125484 euGenes: HUgn9329
    ECgene: GTF3C4 H-InvDB: GTF3C4

    Other Databases showing GTF3C4 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing GTF3C4 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GTF3C4 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for GTF3C4 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for GTF3C4 gene:
    Search GeneIP for patents involving GTF3C4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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