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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GTF3C3 Gene

protein-coding   GIFtS: 50
GCID: GC02M197592

General Transcription Factor IIIC, Polypeptide 3, 102kDa

(Previous names: general transcription factor IIIC, polypeptide 3 (102kD))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
General Transcription Factor IIIC, Polypeptide 3, 102kDa1 2     General Transcription Factor IIIC, Polypeptide 3 (102kD)1
Transcription Factor IIIC Subunit Gamma2 3     TFIIICgamma2
TF3C-gamma2 3     TFiiiC2-1022
TFIIIC1022 3     General Transcription Factor 3C Polypeptide 32
TFIIIC 102 KDa Subunit2 3     Transcription Factor IIIC 102 KDa Subunit3

External Ids:    HGNC: 46661   Entrez Gene: 93302   Ensembl: ENSG000001190417   OMIM: 6048885   UniProtKB: Q9Y5Q93   

Export aliases for GTF3C3 gene to outside databases

Previous GC identifers: GC02M195817 GC02M196341 GC02M197831 GC02M197454 GC02M197336 GC02M189481


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GTF3C3 Gene:
The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and
cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits.
Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for GTF3C3 Gene: 
GTF3C3 (general transcription factor IIIC, polypeptide 3, 102kDa) is a protein-coding gene. Diseases associated with GTF3C3 include ectodermal dysplasia, and microcephaly, and among its related super-pathways are RNA Polymerase III Transcription Initiation and Transcription of tRNA. GO annotations related to this gene include DNA binding.

UniProtKB/Swiss-Prot: TF3C3_HUMAN, Q9Y5Q9
Function: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the
DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_005403.17  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GTF3C3 gene promoter:
         Pax-6   HTF   CUTL1   NF-kappaB   LCR-F1   MEF-2A   NF-kappaB2   HSF2   aMEF-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGTF3C3 promoter sequence
   Search SABiosciences Chromatin IP Primers for GTF3C3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTF3C3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.1   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33.1

GTF3C3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTF3C3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M197592:  view genomic region     (about GC identifiers)

Start:
197,627,756 bp from pter      End:
197,664,492 bp from pter
Size:
36,737 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TF3C3_HUMAN, Q9Y5Q9 (See protein sequence)
Recommended Name: General transcription factor 3C polypeptide 3  
Size: 886 amino acids; 101272 Da
Subunit: Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5
and GTF3C6. Interacts with BRF1 and TBP
Subcellular location: Nucleus
Sequence caution: Sequence=BAB15638.1; Type=Erroneous initiation;
Secondary accessions: Q4ZG48 Q86XJ8 Q8WX84 Q96B44 Q9H5I8 Q9NT97
Alternative splicing: 2 isoforms:  Q9Y5Q9-1   Q9Y5Q9-2   (May be due to exon skipping)

Explore the universe of human proteins at neXtProt for GTF3C3: NX_Q9Y5Q9

Explore proteomics data for GTF3C3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y5Q9

  • GTF3C3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GTF3C3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001193703.1  NP_036218.1  

    ENSEMBL proteins: 
     ENSP00000263956   ENSP00000391724   ENSP00000394065   ENSP00000398385   ENSP00000386465  
     ENSP00000389992   ENSP00000438797   ENSP00000406685  
    Reactome Protein details: Q9Y5Q9
    Human Recombinant Protein Products for GTF3C3: 
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    Cloud-Clone Corp. Proteins for GTF3C3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000127transcription factor TFIIIC complex IDA17409385
    GO:0005654nucleoplasm TAS--

    GTF3C3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GTF: General transcription factors
    TTC: Tetratricopeptide (TTC) repeat domain containing

    4 InterPro protein domains:
     IPR011990 TPR-like_helical
     IPR001440 TPR-1
     IPR013026 TPR-contain_dom
     IPR019734 TPR_repeat

    Graphical View of Domain Structure for InterPro Entry Q9Y5Q9

    ProtoNet protein and cluster: Q9Y5Q9

    UniProtKB/Swiss-Prot: TF3C3_HUMAN, Q9Y5Q9
    Similarity: Contains 11 TPR repeats


    GTF3C3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TF3C3_HUMAN, Q9Y5Q9
    Function: Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the
    DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677contributes to DNA binding IC17409385
    GO:0005515protein binding ----
         
    GTF3C3 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidGTF3C3 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GTF3C3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation0.80
    RNA Polymerase III Transcription Initiation From Type 1 Promoter0.77
    RNA Polymerase III Transcription0.80
    RNA Polymerase III Transcription Initiation From Type 2 Promoter0.74
    RNA Polymerase III Abortive And Retractive Initiation0.80
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    2Assembly of RNA Polymerase-III Initiation Complex
    Assembly of RNA Polymerase-III Initiation Complex0.83
    Transcription of tRNA0.83
    3Transcription
    Transcription0.69
    4Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GTF3C3
        Transcription of tRNA
    Assembly of RNA Polymerase-III Initiation Complex

    5/8        Reactome Pathways for GTF3C3 (see all 8)
        RNA Polymerase III Transcription Initiation
    Transcription
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
    RNA Polymerase III Abortive And Retractive Initiation
    RNA Polymerase III Transcription Initiation From Type 1 Promoter



    GTF3C3 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GTF3C3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/645 Interacting proteins for GTF3C3 (Q9Y5Q92, 3 ENSP000002639564) via UniProtKB, MINT, STRING, and/or I2D (see all 645)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SQSTM1Q135012, 3, ENSP000003744554MINT-7945693 I2D: score=3 STRING: ENSP00000374455
    PLK1P533502, 3, ENSP000003000934MINT-7945693 I2D: score=2 STRING: ENSP00000300093
    ENSG00000258947Q135092, 3MINT-7945693 I2D: score=1 
    GTF3C2Q8WUA42, 3, ENSP000002647204MINT-7945693 I2D: score=1 STRING: ENSP00000264720
    GTF3C4Q9UKN82, 3, ENSP000003612194MINT-7945693 I2D: score=1 STRING: ENSP00000361219
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IC17409385
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0010467gene expression TAS--
    GO:00427915S class rRNA transcription from RNA polymerase III type 1 promoter IC17409385
    GO:0042797tRNA transcription from RNA polymerase III promoter IC17409385

    GTF3C3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTF3C3 (TF3C3)

    Search CenterWatch for drugs/clinical trials and news about GTF3C3 / TF3C3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GTF3C3 gene (2 alternative transcripts): 
    NM_001206774.1  NM_012086.4  

    Unigene Cluster for GTF3C3:

    General transcription factor IIIC, polypeptide 3, 102kDa
    Hs.470996  [show with all ESTs]
    Unigene Representative Sequence: NM_012086
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263956(uc002uts.3 uc010zgu.2) ENST00000481098 ENST00000416690
    ENST00000435252 ENST00000448087(uc002utt.4) ENST00000466862 ENST00000409364(uc002utu.3)
    ENST00000470386 ENST00000455546 ENST00000451088 ENST00000448539
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    SwitchGear 3'UTR luciferase reporter plasmidGTF3C3 3' UTR sequence
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    Additional mRNA sequence: 

    AF085850.1 AF133123.1 AF465407.1 AK025560.1 AK027050.1 AK314718.1 AL137453.1 BC015995.1 
    BC026889.1 BC036952.2 BC043347.1 

    10 DOTS entries:

    DT.416377  DT.100790574  DT.95086071  DT.91974882  DT.416378  DT.95183773  DT.97802304  DT.99968395 
    DT.40130619  DT.97784338 

    24/197 AceView cDNA sequences (see all 197):

    BF594763 AA766807 BM828123 CB157893 AA375402 BM716869 AF465407 AI381293 
    BM838928 AA307628 CB131641 CB160350 R64193 AW295143 BC036952 BX490235 
    AK027050 AI001932 BG288025 BC026889 BQ002883 AA128292 BM852688 BM786549 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for GTF3C3 (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                -                                                                     
    SP2:                                -                                                                                                                     
    SP3:                                                                                                                                                      
    SP4:        -                                                                                                                                             
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for GTF3C3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GTF3C3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAGGCTGGG
    GTF3C3 Expression
    About this image


    See GTF3C3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GTF3C3

    SOURCE GeneReport for Unigene cluster: Hs.470996
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTF3C3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GTF3C3 gene from 9/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gtf3c31 , 5 general transcription factor IIIC, polypeptide 31, 5 89.64(n)1
    93.88(a)1
      1 (27.13 cM)5
    984881  NM_001033194.21  NP_001028366.11 
     543975815 
    chicken
    (Gallus gallus)
    Aves GTF3C31 general transcription factor IIIC, polypeptide 3, 1 more 80.15(n)
    89.32(a)
      424052  NM_001006515.1  NP_001006515.1 
    lizard
    (Anolis carolinensis)
    Reptilia GTF3C36
    general transcription factor IIIC, polypeptide 3, ...
    79(a)
    1 ↔ 1
    GL343280.1(309310-360236)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.214692 Transcribed sequence with weak similarity to protein more 70.07(n)    57049855 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG89501 , 3 CG89501 32(a)3
    44.88(n)1
    33.59(a)1
      369211  NM_137340.31  NP_611184.11 
    worm
    (Caenorhabditis elegans)
    Secernentea ZK856.133
    tag-3151
    transcription factor3
    Protein TAG-3151
    27(a)3
    42.57(n)1
    29.13(a)1
      V(10209414-10212927)3
    1794191  NM_073225.31  NP_505626.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes TFC4(YGR047C)4 One of six subunits of the RNA polymerase III transcription more   --   7(589469-586392) 852938  NP_011561.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G176801 tetratricopeptide repeat (TPR)-containing protein 42.44(n)
    24.44(a)
      838344  NM_101630.4  NP_173210.3 
    rice
    (Oryza sativa)
    Liliopsida Os11g02668001 hypothetical protein 41.88(n)
    25.63(a)
      4350254  NM_001074199.1  NP_001067667.1 


    ENSEMBL Gene Tree for GTF3C3 (if available)
    TreeFam Gene Tree for GTF3C3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/682 SNPs in GTF3C3 are shown (see all 682)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs614969981,2
    C,F--197016060(+) GCGGGT/CGAATT 1 -- ds50012Minor allele frequency- C:0.25WA NA 4
    rs1390345871,2
    C--197016081(+) GAGATC/TGAGAC 1 -- ds50010--------
    rs1815266471,2
    --197016158(+) AGGCAC/TCTGTA 1 -- ds50010--------
    rs1861766481,2
    --197016177(+) TACTCA/GGGAGG 1 -- ds50010--------
    rs1498660401,2
    C--197016278(+) ACTCCA/GTCTCA 1 -- ds50010--------
    rs1179256791,2
    F--197016296(+) AAAAAA/CAAACA 1 -- ds50011Minor allele frequency- C:0.02EA 120
    rs1910406911,2
    C--197016301(+) AAAACA/CAACCT 1 -- ds50010--------
    rs1833059201,2
    --197016510(+) ACCATA/GCTTAG 1 -- ut310--------
    rs1459722561,2
    C--197016595(+) GCTGGG/TTTTTT 1 -- ut310--------
    rs1117749261,2
    C,F--197016690(+) TCGGAG/TCACAG 1 -- ut312Minor allele frequency- T:0.03NA 122

    HapMap Linkage Disequilibrium report for GTF3C3 (197627756 - 197664492 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GTF3C3: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GTF3C3
    DNA2.0 Custom Variant and Variant Library Synthesis for GTF3C3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604888    OMIM disorders: --

    3 diseases for GTF3C3:    About MalaCards
    ectodermal dysplasia    microcephaly    influenza


    GTF3C3 for disorders           About GeneDecksing


    Export disorders for GTF3C3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GTF3C3 gene, integrated from 9 sources (see all 39):
    (articles sorted by number of sources associating them with GTF3C3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III. (PubMed id 10373544)1, 2, 3 Hsieh Y.-J.... Roeder R.G. (1999)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    5. Identification of the hypoxia-inducible factor 2a nucl ear interactome in melanoma cells reveals master proteins involved in melanoma d evelopment. (PubMed id 23275444)1 Steunou A.L....Nieto L. (2013)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    9. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9330 HGNC: 4666 AceView: GTF3C3 Ensembl:ENSG00000119041 euGenes: HUgn9330
    ECgene: GTF3C3 H-InvDB: GTF3C3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GTF3C3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GTF3C3 gene:
    Search GeneIP for patents involving GTF3C3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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