Aliases for GTF3C3 Gene
External Ids for GTF3C3 Gene
Previous GeneCards Identifiers for GTF3C3 Gene
The protein encoded by this gene is part of the TFIIIC2 complex, which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III. The TFIIIC2 complex is composed of six subunits. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for GTF3C3 Gene
GTF3C3 (General Transcription Factor IIIC Subunit 3) is a Protein Coding gene. Diseases associated with GTF3C3 include Tooth Agenesis. Among its related pathways are RNA Polymerase III Transcription Initiation and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.
UniProtKB/Swiss-Prot for GTF3C3 Gene
Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters.