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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GTF3A Gene

protein-coding   GIFtS: 53
GCID: GC13P027998

general transcription factor IIIA

 Explore 36 diseases affiliated with
GTF3A via our new
 Human Malady Compendium 
Biological research products
for GTF3A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
General Transcription Factor IIIA1 2
TFIIIA1 2 3 5
AP21 2
Transcription Factor IIIA2

External Ids:    HGNC: 46621   Entrez Gene: 29712   Ensembl: ENSG000001220347   OMIM: 6008605   UniProtKB: Q926643   

Export aliases for GTF3A gene to outside databases

Previous GC identifers: GC13P025978 GC13P021978 GC13P026928 GC13P025796 GC13P026896 GC13P008820


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GTF3A:
The product of this gene is a zinc finger protein with nine Cis(2)-His(2) zinc finger domains. It functions as an RNA
polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp
internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable
preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to
form the complete transcription complex. The protein is thought to be translated using a non-AUG translation
initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TF3A_HUMAN, Q92664
Function: Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is
required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May
initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes

Gene Wiki entry for GTF3A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.1  NT_024524.14  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GTF3A
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGTF3A promoter sequence
   Search SABiosciences Chromatin IP Primers for GTF3A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTF3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.3-q13.1   Ensembl cytogenetic band:  13q12.2   HGNC cytogenetic band: 13q12.3-q13.1

GTF3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GTF3A gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P027998:  view genomic region     (about GC identifiers)

Start:
27,998,681 bp from pter      End:
28,009,958 bp from pter
Size:
11,278 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TF3A_HUMAN, Q92664 (See protein sequence)
Recommended Name: Transcription factor IIIA  
Size: 365 amino acids; 41515 Da
Subcellular location: Nucleus
Caution: It is uncertain whether Met-1 is the initiator. Based on the lack of an in-frame AUG codon, mammalian TFIIIA
may be translated from this non-AUG initiation site, which has a good Kozak context and which is well conserved among
mammals
Sequence caution: Sequence=BAA06988.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=BAA06988.1; Type=Frameshift; Positions=319, 330;
Secondary accessions: B7ZBK5 Q12963 Q13097
Alternative splicing: 2 isoforms:  Q92664-1   Q92664-2   

Explore the universe of human proteins at neXtProt for GTF3A: NX_Q92664

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q92664

  • GTF3A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_002088.2  
    ENSEMBL proteins: 
     ENSP00000370532   ENSP00000409175   ENSP00000389655   ENSP00000387806   ENSP00000393050  
    Reactome Protein details: Q92664
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GTF3A

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--


    GTF3A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GTF3A for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q92664

    ProtoNet protein and cluster: Q92664

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: TF3A_HUMAN, Q92664
    Similarity: Contains 9 C2H2-type zinc fingers


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TF3A_HUMAN, Q92664
    Function: Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is
    required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May
    initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes

         Genatlas biochemistry entry for GTF3A:
    general transcription factor IIIA,Xenopus homolog,required for initiation of transcription of 5S RNA

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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0003723RNA binding IEA--
    GO:0008270zinc ion binding IEA--


    GTF3A for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/6 super-pathways (see all 6About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1RNA Polymerase III Transcription Initiation
    RNA Polymerase III Abortive And Retractive Initiation1.00
    RNA Polymerase III Transcription Initiation From Type 1 Promoter0.77
    RNA Polymerase III Transcription Initiation1.00
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription0.59
    RNA Polymerase III Transcription1.00
    2Transcription
    Transcription1.00
    3Assembly of RNA Polymerase-III Initiation Complex
    Assembly of RNA Polymerase-III Initiation Complex1.00
    4Adipogenesis
    Adipogenesis1.00
    5IL4-mediated signaling events
    IL4-mediated signaling events1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for GTF3A
        Assembly of RNA Polymerase-III Initiation Complex

    2 BioSystems Pathways for GTF3A 
        Adipogenesis
    IL4-mediated signaling events

    5/7        Reactome Pathways for GTF3A (see all 7)
        RNA Polymerase III Transcription Initiation
    RNA Polymerase III Transcription Initiation From Type 1 Promoter
    Transcription
    RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
    RNA Polymerase III Transcription



    GTF3A for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GTF3A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/34 Interacting proteins for GTF3A (Q926643 ENSP000003705324) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005193, ENSP000003614234I2D: score=1 STRING: ENSP00000361423
    EPN1Q9Y6I33, ENSP000004062094I2D: score=1 STRING: ENSP00000406209
    FYNP062413, ENSP000003576564I2D: score=1 STRING: ENSP00000357656
    CXCR2P250253, ENSP000003196354I2D: score=2 STRING: ENSP00000319635
    GTF3C2Q8WUA43, ENSP000002647204I2D: score=2 STRING: ENSP00000264720
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006383transcription from RNA polymerase III promoter TAS--
    GO:0009303rRNA transcription TAS8063702
    GO:0010467gene expression TAS--


    GTF3A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GTF3A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GTF3A
    10/22 Novoseek chemical compound relationships for GTF3A gene (see all 22)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5s-rrna 70.3 9 8557698 (2), 10559190 (2)
    zinc 70 162 8336715 (6), 9242690 (6), 8419919 (5), 8411165 (5) (see all 62)
    cpds 43.1 5 15913668 (3), 10064604 (1)
    rrna 35.8 19 19211543 (4), 7729570 (3), 9426240 (2), 11926995 (2) (see all 8)
    fibrinogen 34.1 9 18558494 (2), 16045623 (1), 20007717 (1), 16640587 (1) (see all 6)
    histidine 26.4 4 12665246 (1), 1511742 (1), 8411165 (1)
    cyanogen bromide 16.7 1 11853545 (1)
    cysteine 5.91 3 12665246 (1), 1511742 (1)
    serine 5.52 10 11853545 (2), 16650464 (1), 19415717 (1), 16251496 (1) (see all 9)
    pravastatin 5.4 2 8759384 (1), 8966112 (1)

    Search CenterWatch for drugs/clinical trials and news about GTF3A / TF3A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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    About This Section

    REFSEQ mRNAs for GTF3A gene: 
    NM_002097.2  

    Unigene Cluster for GTF3A:

    General transcription factor IIIA
    Hs.445977  [show with all ESTs]
    Unigene Representative Sequence: AK057993
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381140(uc001ure.2 uc001urf.2) ENST00000435781 ENST00000419181
    ENST00000438571 ENST00000466776 ENST00000470606(uc001urg.2) ENST00000493903
    ENST00000439403 ENST00000482655

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    Additional cDNA sequence: 

    AK057993.1 AK130295.1 BC143711.1 D32257.1 U14134.1 U20272.1 

    19 DOTS entries:

    DT.95303395  DT.100820167  DT.91941950  DT.452672  DT.91960847  DT.100773125  DT.87008500  DT.91763823 
    DT.100739738  DT.107228  DT.91763828  DT.100820163  DT.120769632  DT.100820169  DT.91876450  DT.95303407 
    DT.100820164  DT.120769642  DT.120769652 

    24/438 AceView cDNA sequences (see all 438):

    CB140928 BG519635 BM562682 BX381791 AA470032 AA603666 BU784762 AA281589 
    AI075001 U14134 AI934640 BE909957 T73944 AI201445 BU517107 AA933690 
    BE889997 BM826505 BI467382 AW026082 BU857459 BI764623 BM453967 CR596081 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for GTF3A (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b
    SP1:                          -     -     -     -                 -                       -     -     -                 -                           
    SP2:                                                              -                       -     -     -                 -                           
    SP3:                          -     -     -     -                 -                       -     -     -     -           -                           
    SP4:                                                              -                       -     -     -     -           -                           
    SP5:                                                                                      -     -     -                 -                           


    ECgene alternative splicing isoforms for GTF3A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GTF3A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See GTF3A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GTF3A

    SOURCE GeneReport for Unigene cluster: Hs.445977

    UniProtKB/Swiss-Prot: TF3A_HUMAN, Q92664
    Tissue specificity: Ubiquitous

        SABiosciences Expression via Pathway-Focused PCR Array including GTF3A: 
              Mesenchymal Stem Cell in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GTF3A gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves GTF3A1 general transcription factor IIIA 68.97(n)
    67.44(a)
      418931  NM_001113571.1  NP_001107043.1 
    lizard
    (Anolis carolinensis)
    Reptilia GTF3A6
    --
    60(a)
    1 ↔ 1
    GL343306.1(1157332-1169069)
    African clawed frog
    (Xenopus laevis)
    Amphibia LOC3977772 TFIIIA mRNA 75.22(n)    K02938.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.147502 Transcribed sequence with weak similarity to protein more 70.84(n)    CA474391.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG96091 , 3 RNA polymerase III transcription factor3
    CG96091
    32(a)3
    42.6(n)1
    33.56(a)1
      15A83
    326631  NM_132933.21  NP_573161.11 


    ENSEMBL Gene Tree for GTF3A (if available)
    TreeFam Gene Tree for GTF3A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GTF3A gene
    ZXDA2  ZXDC2  ZXDB2  
    18/149 SIMAP similar genes for GTF3A using alignment to 5 protein entries:     TF3A_HUMAN (see all proteins) (see all similar genes):
    DKFZp686O1631    SP3    DKFZp686N0199    KLF13    YY1    ZNF75A
    A-328A3.4    FIZ1    SP1    ZNF55    ZNF181    ZNF83
    KLF1    ZNF423    ZNF211    ZNF544    KLF16    ZBTB47

    GTF3A for paralogs           About GeneDecksing


    5/6 Pseudogenes.org Pseudogenes for GTF3A (see all 6)
    PGOHUM00000247850 PGOHUM00000241122 PGOHUM00000235719 PGOHUM00000232598 PGOHUM00000232973


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/262 NCBI SNPs in GTF3A are shown (see all 262    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2002354531,2
    --27996694(+) AACAT-/GGTAAA 1 -- us2k10--------
    rs1458723081,2
    --27996746(+) TGGTGC/TGCACC 1 -- us2k10--------
    rs37594351,2
    C,F,H,--27996813(-) CTGCAA/CCCTCC 1 -- us2k17Minor allele frequency- C:0.26NA CSA WA EA 366
    rs1125643741,2
    C,--27996882(+) TTGTC-/AAAAAA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs799045931,2
    --27996893(+) AAAAAG/AAAAGA 1 -- us2k12Minor allele frequency- A:0.19NA 122
    rs2015541231,2
    --27996893(+) AAAAA-/GAAAGA 1 -- us2k10--------
    rs1378916841,2
    --27996938(+) GCAGAA/GAGAAA 1 -- us2k10--------
    rs1842936951,2
    --27996978(+) AAAGAA/GCAAAG 1 -- us2k10--------
    rs777775071,2
    F,--27997028(+) GATCCT/CATTAG 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1146961501,2
    F,--27997042(+) CTTTAC/TGTGGA 1 -- us2k11Minor allele frequency- T:0.09WA 118

    HapMap Linkage Disequilibrium report for GTF3A (27998681 - 28009958 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GTF3A: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GTF3A
    DNA2.0 Custom Variant and Variant Library Synthesis for GTF3A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GTF3A for disorders           About GeneDecksing

    OMIM gene information: 600860    OMIM disorders: --

    20/36 diseases for GTF3A (see all 36):    About MalaCards
    open-angle glaucoma    primary open angle glaucoma    age related macular degeneration    glanzmann's thrombasthenia
    clear cell renal cell carcinoma    macular degeneration    thrombasthenia    sleep apnea
    endocarditis    renal cell carcinoma    acute liver failure    infective endocarditis
    glaucoma    coronary heart disease    gestational diabetes    digeorge syndrome
    apnea    adrenocortical tumor    prostate carcinoma in situ    squamous cell carcinoma

    1 disease from the University of Copenhagen DISEASES database for GTF3A:
    Prostate carcinoma in situ

    10/11 Novoseek disease relationships for GTF3A gene (see all 11)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hypomania 25.1 1 15536301 (1)
    breast cancer 4.22 2 17353919 (1), 16708380 (1)
    psychiatric disorder 3.52 1 15962922 (1)
    stroke 2.98 1 15491926 (1)
    metastasis 2.7 1 19816005 (1)
    necrosis 0 5 9696492 (1), 11005132 (1), 11259850 (1), 11834836 (1)
    inflammation 0 2 15026723 (1), 20470300 (1)
    tumors 0 12 11814676 (1), 15317818 (1), 2016567 (1), 9696492 (1) (see all 10)
    cancer 0 2 17448239 (1), 19765756 (1)
    endocarditis 0 1 17393025 (1)


    Export disorders for GTF3A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GTF3A gene, integrated from 9 sources (see all 197):
    (articles sorted by number of sources associating them with GTF3A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA. (PubMed id 7789179)1, 2, 3, 9 Arakawa H.... Nakamura Y. (1995)
    2. Purification and characterization of human transcription factor IIIA. (PubMed id 8063702)1, 2, 9 Moorefield B. and Roeder R.G. (1994)
    3. Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA. (PubMed id 7622052)1, 2, 9 Drew P.D....Becker K.G. (1995)
    4. cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA. (PubMed id 11814676)1, 9 Hanas J.S....Moreland R.J. (2002)
    5. Identification of a transcription factor IIIA-interacting protein. (PubMed id 10756201)1, 9 Moreland R.J.... Hanas J.S. (2000)
    6. Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev. (PubMed id 8610146)1, 9 Fridell R.A....Cullen B.R. (1996)
    7. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1 Speliotes E.K....Loos R.J. (2010)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Polyubiquitination of prolactin receptor stimulates its internalization, postinternalization sorting, and degradation via the lysosomal pathway. (PubMed id 18573876)1 Varghese B....Fuchs S.Y. (2008)
    10. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2971 HGNC: 4662 AceView: GTF3A Ensembl:ENSG00000122034 euGenes: HUgn2971
    ECgene: GTF3A H-InvDB: GTF3A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GTF3A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GTF3A gene:
    Search GeneIP for patents involving GTF3A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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