Aliases for GTF2H3 Gene
External Ids for GTF2H3 Gene
Previous GeneCards Identifiers for GTF2H3 Gene
This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012]
GeneCards Summary for GTF2H3 Gene
GTF2H3 (General Transcription Factor IIH, Polypeptide 3, 34kDa) is a Protein Coding gene. Among its related pathways are Infectious disease and Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein N-terminus binding.
UniProtKB/Swiss-Prot for GTF2H3 Gene
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Anchors XPB