Aliases for GTF2E1 Gene
External Ids for GTF2E1 Gene
Previous GeneCards Identifiers for GTF2E1 Gene
GeneCards Summary for GTF2E1 Gene
GTF2E1 (General Transcription Factor IIE Subunit 1) is a Protein Coding gene. Diseases associated with GTF2E1 include Trichothiodystrophy 1, Photosensitive. Among its related pathways are Assembly of RNA Polymerase-II Initiation Complex and RNA Polymerase II Transcription Initiation And Promoter Clearance. GO annotations related to this gene include sequence-specific DNA binding.
UniProtKB/Swiss-Prot for GTF2E1 Gene
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.