GTF2B Gene
protein-coding GIFtS: 64
GCID: GC01M089318
|
|
general transcription factor IIB
| |
Aliases
for GTF2B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| General Transcription Factor IIB1 2 | | S300-II2 3 | | TFIIB1 2 3 5 | | RNA Polymerase II Transcription Factor IIB2 | | TF2B2 3 5 | | Transcription Initiation Factor IIB2 | | General Transcription Factor TFIIB2 3 | | |
Export aliases for GTF2B gene to outside databasesPrevious GC identifers: GC01M089795 GC01M088488 GC01M088655 GC01M088785 GC01M089030 GC01M087435 |
Summaries
for GTF2B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for GTF2B:
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcriptioninitiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) withtranscription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initiallyrecognizes the promoter sequence, and RNA polymerase II. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TF2B_HUMAN, Q00403Function: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II
Gene Wiki entry for GTF2B (Transcription factor II B)
|
Genomic Views
for GTF2B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GTF2B gene promoter:
TBP AP-1 TFIID FOXO1a c-Jun FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for GTF2B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTF2B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p22-p21 Ensembl cytogenetic band: 1p22.2 HGNC cytogenetic band: 1p22-p21GTF2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M089318: view genomic region
(about GC identifiers)
Start:
|
89,318,321 bp from pter |
End:
|
89,357,627 bp from pter |
Size:
|
39,307 bases |
Orientation:
|
minus strand |
|
Proteins
for GTF2B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TF2B_HUMAN, Q00403 (See
protein sequence)Recommended Name: Transcription initiation factor IIB Size: 316 amino acids; 34833 Da
Cofactor: Binds 1 zinc ion per subunit
Subunit: Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB (DAB-complex) which is then recognized bypolymerase II. Interacts with the transcription elongation factor TCEA2. Interacts with HIV-1 Vpr. Interacts withGPBP1 (By similarity). Interacts with Epstein-Barr virus EBNA2
Subcellular location: Nucleus
6/7 PDB 3D structures from  and Proteopedia  for GTF2B (see all 7):1C9B (3D)
1DL6 (3D)
1RLY (3D)
1RO4 (3D)
1TFB (3D)
1VOL (3D)
Secondary accessions: A8K1A7 Q5JS30Explore the universe of human proteins at neXtProt for GTF2B: NX_Q00403
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q00403
GTF2B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001505.1
ENSEMBL proteins: ENSP00000359531 ENSP00000415741 ENSP00000402345 Reactome Protein details: Q00403
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
GTF2B for ontologies About GeneDecksing
GTF2B Antibody Products:
Assay Products for GTF2B: |
Protein
Domains /
Families
for GTF2B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GTF2B for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q00403ProtoNet protein and cluster: Q00403 3 Blocks protein families: IPB000812 Transcription factor TFIIB family IPB006670 Cyclin IPB013137 Zinc finger
UniProtKB/Swiss-Prot: TF2B_HUMAN, Q00403Similarity: Belongs to the TFIIB familySimilarity: Contains 1 TFIIB-type zinc finger |
Function
for GTF2B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TF2B_HUMAN, Q00403Function: General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II Genatlas biochemistry entry for GTF2B:general transcription factor IIB,35 kDa
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GTF2B (NM_001514) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GTF2B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GTF2B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTF2B |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
GTF2B for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for GTF2B:
|
Pathways & Interactions
for GTF2B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/14 super-pathways (see all 14) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Formation of RNA Pol II elongation complex | | | 2 | Assembly of RNA Polymerase-II Initiation Complex | | | 3 | HIV Infection | | | 4 | Late Phase of HIV Life Cycle | | | 5 | Transcription | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for GTF2B
5/11 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GTF2B (see all 11)
1 
Cell Signaling Technology (CST) Pathway for GTF2B
1  GeneGo (Thomson Reuters) Pathway for GTF2B
1  BioSystems Pathway for GTF2B
5/19 
Reactome Pathways for GTF2B (see all 19)
1 
Kegg Pathway (Kegg details for GTF2B):
GTF2B for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GTF2B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/205 Interacting proteins for GTF2B (Q004031, 2, 3 ENSP000003595314) via UniProtKB, MINT, STRING, and/or I2D (see all 205)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006352 | DNA-dependent transcription, initiation |
-- | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0006368 | transcription elongation from RNA polymerase II promoter |
TAS | -- |
GTF2B for ontologies About GeneDecksing
|
Drugs & Compounds
for GTF2B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GTF2B for compounds About GeneDecksing
 Browse Tocris compounds for GTF2B
10/16 Novoseek chemical compound relationships for GTF2B gene (see all 16) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tbps |
60.6 |
1 |
12446790 (1) |
| 1,25 dihydroxy vitamin d3 |
43.7 |
1 |
9013769 (1) |
| zinc |
40.4 |
24 |
18631123 (3), 7891725 (2), 9013769 (2), 14536083 (2) (see all 13) |
| phosphodiester |
31 |
2 |
10872452 (1), 8631733 (1) |
| vitamin d |
25.3 |
5 |
12520521 (1), 9379138 (1), 9013769 (1), 12529369 (1) (see all 5) |
| retinoic acid |
4.49 |
2 |
9808423 (1), 8887661 (1) |
| atp |
0 |
1 |
8631733 (1) |
| estradiol |
0 |
2 |
15079859 (1) |
| steroid |
0 |
2 |
9379138 (1), 8990171 (1) |
| proline |
0 |
1 |
9089417 (1) |
Search CenterWatch for drugs/clinical trials and news about GTF2B / TF2B
|
Transcripts
for GTF2B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GTF2B gene: NM_001514.5 Unigene Cluster for GTF2B: General transcription factor IIB Hs.481852 [show with all ESTs]Unigene Representative Sequence: NM_0015147 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000370500(uc001dmo.4 uc009wcw.1) ENST00000448623 ENST00000494819
ENST00000418217 ENST00000486078 ENST00000471296 ENST00000471471
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: GTF2B (NM_001514) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GTF2B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GTF2B |
Additional cDNA sequence: AB451296.1 AK289822.1 BC020597.1 M76766.1 S44184.1 8 DOTS entries: DT.217227 DT.92437115 DT.100651698 DT.95270437 DT.92437109 DT.92437111 DT.92437112 DT.100668090 24/246 AceView cDNA sequences (see all 246): AA313473 AI803543 AW953773 CB161485 U47720 BU182783 F02944 BP379342 BI761841 BX488793 AW303945 BC020597 BX107185 BQ637247 AI167866 AA031866 BM314476 BF432599 AI948700 CR600115 AL546491 NM_001514 CR598774 BF438221
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for GTF2B About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | - | | - | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for GTF2B
|
Expression
for GTF2B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GTF2B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTACGCATTC
About this image
See GTF2B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GTF2B
SOURCE GeneReport for Unigene cluster: Hs.481852
SABiosciences Expression via Pathway-Focused PCR Array including GTF2B:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GTF2B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GTF2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GTF2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GTF2B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTF2B |
Orthologs
for GTF2B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for GTF2B gene from 9/38 species (see all 38) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
GTF2B1 |
general transcription factor IIB |
85.55(n)
97.78(a) |
|
424518 XM_422356.3 XP_422356.3 |
lizard
(Anolis carolinensis) |
Reptilia |
GTF2B6 |
-- |
94(a) |
1 ↔ 1 |
4(95890775-95907992) |
African clawed frog
(Xenopus laevis) |
Amphibia |
gtf2b-A2 |
general transcription factor IIB |
79.98(n) |
|
X62868.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufc44c112 |
wufc44c11 |
78.48(n) |
|
324823 BC055569.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
TfIIB1 , 3 |
transcription initiation from Pol II
promoter more3
Transcription factor IIB1 |
79(a)3
65.71(n)1
79.37(a)1 |
|
344301 NM_057540.31 NP_476888.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
ttb-11 , 3 |
transcription factor3
Protein TTB-11 |
61(a)3
60.76(n)1
62.54(a)1 |
|
V(156222-157373)3
1785441 NM_070745.31 NP_503146.11 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
SUA7(YPR086W)4
SUA71 |
Transcription factor TFIIB, a general transcription more4
Sua7p1 |
47.14(n)1
37.5(a)1 |
|
16(710101-711138)4
8562011, 4 NP_015411.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
TFIIB1 |
transcription initiation factor IIB-1 |
56.16(n)
49.64(a) |
|
818761 NM_129726.3 NP_181694.1 |
rice
(Oryza sativa) |
Liliopsida |
Os09g05348001 |
hypothetical protein |
53.4(n)
48.59(a) |
|
4347689 NM_001070310.1 NP_001063775.1 |
ENSEMBL Gene Tree for GTF2B (if available)
TreeFam Gene Tree for GTF2B (if available) |
Paralogs
for GTF2B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for GTF2B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for GTF2B (89318321 - 89357627 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for GTF2B
1 CNV: 53657 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GTF2B |
|
Disorders
/ Diseases
for GTF2B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GTF2B for disorders About GeneDecksing
OMIM gene information: 189963
OMIM disorders: --
12  diseases for GTF2B: About MalaCardsherpes simplex cockayne syndrome insulin resistance lipodystrophy
retinoblastoma hepatocellular carcinoma neurodegeneration immunodeficiency
carcinoma thyroiditis malaria neuronitis
6 Novoseek disease relationships for GTF2B gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| herpes simplex |
39.7 |
8 |
14764096 (1), 7791769 (1), 8972203 (1), 11371188 (1) (see all 7) |
| retinoblastoma |
36 |
3 |
9433129 (1), 8628726 (1), 8434021 (1) |
| carcinoma embryonal |
10.9 |
2 |
7878015 (1), 8887661 (1) |
| immunodeficiency |
3.52 |
3 |
7707528 (1), 8800208 (1), 9292011 (1) |
| tumors |
0.441 |
1 |
8628726 (1) |
| shock |
0 |
5 |
16330756 (2), 17994014 (1), 11005381 (1), 15149597 (1) |
Export disorders for GTF2B gene to outside databases
|
Publications
for GTF2B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GTF2B gene, integrated from 9 sources (see all 351):
(articles sorted by number of sources associating them with GTF2B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning of a human gene encoding the general transcription initiation factor IIB. (PubMed id 1876184)1, 2, 3, 9 Ha I.... Reinberg D. (1991)
- The HIV-1 Vpr co-activator induces a conformational change in TFIIB. (PubMed id 10359081)1, 2, 9 Agostini I.... Sire J. (1999)
- Sequence of general transcription factor TFIIB and relationships to other initiation factors. (PubMed id 1946368)1, 2, 9 Malik S.... Roeder R.G. (1991)
- Structure of a (Cys3His) zinc ribbon, a ubiquitous motif in archaeal and eucaryal transcription. (PubMed id 11045620)1, 2, 9 Chen H.T.... Scott R.A. (2000)
- Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein. (PubMed id 7671313)1, 2, 9 Bagby S.... Ikura M. (1995)
- The human immunodeficiency virus type 1 Vpr transactivator: cooperation with promoter-bound activator domains and binding to TFIIB. (PubMed id 8800208)1, 2, 9 Agostini I....Sire J. (1996)
- Crystal structure of a TFIIB-TBP-TATA-element ternary complex. (PubMed id 7675079)1, 2, 9 Nikolov D.B.... Burley S.K. (1995)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Isolation and characterization of a cDNA encoding a new type of human transcription elongation factor S-II. (PubMed id 8566795)1, 2 Umehara T.... Horikoshi M. (1995)
|
External Searches for GTF2B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GTF2B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GTF2B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GTF2B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for GTF2B | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for GTF2B gene:
Search GeneIP for patents involving GTF2B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for GTF2B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for GTF2B | | OriGene shRNA RFP for GTF2B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GTF2B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GTF2B | | | OriGene Protein Over-expression Lysate for GTF2B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for GTF2B | | OriGene 3'-UTR Clone for GTF2B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GTF2B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for GTF2B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for GTF2B | | OriGene Custom Protein Services for GTF2B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GTF2B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GTF2B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GTF2B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GTF2B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GTF2B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GTF2B |
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| | Antibodies & Assays for GTF2B |
| | | | Search Tocris compounds for GTF2B |
| |  |  |  |  | | | | | | Recombinant Protein for GTF2B |
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 | | | GTF2B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GTF2B |
|  |  |  | | | | ThermoFisher Antibodies for GTF2B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GTF2B |
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