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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GSX1 Gene

protein-coding   GIFtS: 45
GCID: GC13P028366

GS Homeobox 1


(Previous symbol: GSH1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
GS Homeobox 11 2
GSH11 2 3
Homeobox Protein GSH-12 3
Gsh-12
Genomic Screened Homeo Box 12
GS Homeo Box Protein 12

External Ids:    HGNC: 203741   Entrez Gene: 2194092   Ensembl: ENSG000001698407   UniProtKB: Q9H4S23   

Export aliases for GSX1 gene to outside databases

Previous GC identifers: GC13P027265 GC13P009187


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GSX1 Gene: 
GSX1 (GS homeobox 1) is a protein-coding gene. Diseases associated with GSX1 include moebius syndrome, and facial paralysis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is HOXA7.

UniProtKB/Swiss-Prot: GSX1_HUMAN, Q9H4S2
Function: Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the
transcription of the GHRH gene. Plays an important role in pituitary development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_024524.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GSX1 gene promoter:
         Egr-3   HFH-3   Pbx1a   NRSF form 1   Nkx2-5   NRSF form 2   Arnt   FOXI1   PPAR-alpha   Nkx6-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGSX1 promoter sequence
   Search SABiosciences Chromatin IP Primers for GSX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GSX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12.2   Ensembl cytogenetic band:  13q12.2   HGNC cytogenetic band: 13q12.2

GSX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GSX1 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P028366:  view genomic region     (about GC identifiers)

Start:
28,366,780 bp from pter      End:
28,368,905 bp from pter
Size:
2,126 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GSX1_HUMAN, Q9H4S2 (See protein sequence)
Recommended Name: GS homeobox 1  
Size: 264 amino acids; 27883 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q9UD62

Explore the universe of human proteins at neXtProt for GSX1: NX_Q9H4S2

Explore proteomics data for GSX1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H4S2

  • GSX1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GSX1 Protein Expression
    REFSEQ proteins: NP_663632.1  
    ENSEMBL proteins: 
     ENSP00000304331  

    Human Recombinant Protein Products for GSX1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for GSX1
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for GSX1
    GenScript Custom Purified and Recombinant Proteins Services for GSX1
    Novus Biologicals GSX1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GSX1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    GSX1 for ontologies           About GeneDecksing



    GSX1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
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    OriGene Custom Antibody Services for GSX1
    GenScript Custom Superior Antibodies Services for GSX1
    Novus Biologicals GSX1 Antibody
    Abcam antibodies for GSX1
    Cloud-Clone Corp. Antibodies for GSX1 
    ThermoFisher Antibodies for GSX1
    LSBio Antibodies in human, mouse, rat for GSX1 

    Assay Products for GSX1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for GSX1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GSX1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for GSX1 
    Cloud-Clone Corp. CLIAs for GSX1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    HOXL: Homeoboxes / ANTP class : HOXL subclass

    4 InterPro protein domains:
     IPR020479 Homeobox_metazoa
     IPR017970 Homeobox_CS
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like

    Graphical View of Domain Structure for InterPro Entry Q9H4S2

    ProtoNet protein and cluster: Q9H4S2

    1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

    UniProtKB/Swiss-Prot: GSX1_HUMAN, Q9H4S2
    Similarity: Belongs to the Antp homeobox family
    Similarity: Contains 1 homeobox DNA-binding domain


    GSX1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GSX1_HUMAN, Q9H4S2
    Function: Probable transcription factor that binds to the DNA sequence 5'-GC[TA][AC]ATTA[GA]-3'. Activates the
    transcription of the GHRH gene. Plays an important role in pituitary development

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IDA11731616
         
    GSX1 for ontologies           About GeneDecksing


    Phenotypes:
         11 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gsx1):
     behavior/neurological  craniofacial  endocrine/exocrine gland  growth/size  hematopoietic system 
     immune system  mortality/aging  nervous system  reproductive system  skeleton 
     vision/eye 

    GSX1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Gsx1tm1Ssp for GSX1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GSX1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GSX1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GSX1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GSX1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GSX1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GSX1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GSX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GSX1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GSX1
    Sirion Biotech Customized adenovirus for overexpression of GSX1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for GSX1 (see all 6)
    OriGene ORF clones in mouse, rat for GSX1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GSX1 (NM_145657)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GSX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GSX1
    Sirion Biotech Customized lentivirus for stable overexpression of GSX1 
                         Customized lentivirus expression plasmids for stable overexpression of GSX1 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for GSX1
    Search LifeMap BioReagents cell lines for GSX1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GSX1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GSX1

    1 Interacting protein for GSX1 (Q9H4S23) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IRF9Q009783I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0021527spinal cord association neuron differentiation IEA--
    GO:0021854hypothalamus development IEA--
    GO:0021984adenohypophysis development IEA--

    GSX1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GSX1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GSX1

    1 Novoseek inferred chemical compound relationship for GSX1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gamma-glutamylcysteine 78.6 4 14530437 (1), 11402187 (1), 17853356 (1), 17253982 (1)

    Search CenterWatch for drugs/clinical trials and news about GSX1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GSX1 gene: 
    NM_145657.1  

    Unigene Cluster for GSX1:

    GS homeobox 1
    Hs.351785
    Unigene Representative Sequence: NM_145657
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000302945(uc001urr.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GSX1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GSX1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GSX1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GSX1
    Clone
    Products:
         
    OriGene clones in human, mouse for GSX1 (see all 6)
    OriGene ORF clones in mouse, rat for GSX1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GSX1 (NM_145657)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GSX1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GSX1
    Sirion Biotech Customized lentivirus for stable overexpression of GSX1 
                         Customized lentivirus expression plasmids for stable overexpression of GSX1 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for GSX1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GSX1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GSX1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GSX1

    Additional mRNA sequence: AB044157.1 

    1 DOTS entry:

    DT.95187651 

    2 AceView cDNA sequences:

    NM_145657 AB044157 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GSX1 expression in normal human tissues (normalized intensities)      GSX1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTCCGTCCT
    GSX1 Expression
    About this image


    GSX1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/16 selected tissues (see all 16) fully expand
     
     Brain (Nervous System)    fully expand to see all 16 entries
             d5 Neural Progenitor Cells dP5 Neural Domain
             Thalamus
             Septum   
     
     Neural Tube (Nervous System)    fully expand to see all 3 entries
             d5 Neural Progenitor Cells dP5 Neural Domain
             Telencephalon
     
     Heart (Cardiovascular System)    fully expand to see all 3 entries
             heart/ventricle   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Membranous Facial Bones
             skeleton/cranium   
     
     Spinal Cord (Nervous System)    fully expand to see all 2 entries
             Ventral Horn   

    See GSX1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GSX1

    SOURCE GeneReport for Unigene cluster: Hs.351785
        SABiosciences Custom PCR Arrays for GSX1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GSX1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GSX1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GSX1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GSX1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GSX1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GSX1 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gsx11 , 5 GS homeobox 11, 5 87.99(n)1
    98.08(a)1
      5 (86.79 cM)5
    148421  NM_008178.21  NP_032204.11 
     1471886965 
    chicken
    (Gallus gallus)
    Aves LOC1008587221 GS homeobox 1-like 79.51(n)
    82.79(a)
      100858722  XM_003640564.1  XP_003640612.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gsx11 GS homeobox 1 69.01(n)
    75.62(a)
      449875  NM_001012251.1  NP_001012251.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ind6
    intermediate neuroblasts defective
    23(a)
    1 → many
    3L(15035894-15037024)


    ENSEMBL Gene Tree for GSX1 (if available)
    TreeFam Gene Tree for GSX1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GSX1 gene
    HOXA72  HOXA12  HOXB32  HOXD12  HOXA22  HOXB52  HOXC62  HOXC52  
    GSX22  HOXB42  HOXA52  HOXA42  HOXD32  HOXA62  HOXC82  HOXA32  
    HOXD82  HOXB62  HOXB12  HOXB82  HOXD42  HOXB22  PDX12  HOXB72  
    HOXC42  
    1 SIMAP similar gene for GSX1 using alignment to 1 protein entry:     GSX1_HUMAN:
    GSX2

    GSX1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/61 SNPs in GSX1 are shown (see all 61)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1511613721,2
    --9185136(+) GGTCTC/GGCTCT 1 -- us2k10--------
    rs770634091,2
    F--9185297(+) CTTGCC/TCCCCA 1 -- us2k11Minor allele frequency- T:0.50NA 2
    rs12310561,2
    C,F,A,H--9185304(+) CCCACC/TCCATG 1 -- us2k113Minor allele frequency- T:0.35NA WA CSA EA 377
    rs1931677151,2
    --9185340(+) CCTTAC/TTCCTG 1 -- us2k10--------
    rs1503597511,2
    --9185595(+) ATTCAC/GGGCTC 1 -- us2k10--------
    rs1853905871,2
    --9185629(+) GGTTCC/TAATAA 1 -- us2k10--------
    rs755773341,2
    C,F--9185648(+) GTAAAC/TGTCTC 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs1879065951,2
    --9185649(+) TAAACC/GTCTCC 1 -- us2k10--------
    rs1926843571,2
    --9185668(+) GTCCCC/GGGCTG 1 -- us2k10--------
    rs1837442071,2
    --9185726(+) CTGGGC/TGAAAC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GSX1 (28366780 - 28368905 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GSX1: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GSX1
    DNA2.0 Custom Variant and Variant Library Synthesis for GSX1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    5 diseases for GSX1:    About MalaCards
    moebius syndrome    facial paralysis    paralysis    neuronitis
    pancreatitis


    GSX1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GSX1

    Export disorders for GSX1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GSX1 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with GSX1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Homeobox protein Gsh-1-dependent regulation of the rat GHRH gene promoter. (PubMed id 11731616)1, 2, 9 Mutsuga N.... Saito H. (2001)
    2. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1, 4 Anney R.J....Gill M. (2008)
    3. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
    4. Molecular genetic screening of MBS1 locus on chromoso me 13 for microdeletions and exclusion of FGF9, GSH1 and CDX2 as causative gene s in patients with Moebius syndrome. (PubMed id 19460469)1, 9 Uzumcu A....Basaran S. (2009)
    5. Identification of homeobox genes expressed in human haemopoietic progenitor cells. (PubMed id 7518789)2 Moretti P....D'Andrea R. (1994)
    6. Novel insight into the regulation of GSH biosynthesis in higher plants. (PubMed id 17853356)9 Rausch T....Wachter A. (2007)
    7. The Arabidopsis Ethylene-Insensitive 2 gene is required for lead resistance. (PubMed id 19153049)9 Cao S....Ma X. (2009)
    8. Transcriptional profiling of the Candida albicans Ssk1p receiver domain point mutants and their virulence. (PubMed id 18616606)9 Menon V....Chauhan N. (2008)
    9. ParaHox genes in pancreatic cell cultures: effects on the insulin promoter regulation. (PubMed id 18274620)9 Rosanas-Urgell A....Marfany G. (2008)
    10. Cytoplasmic glutathione redox status determines survival upon exposure to the thiol-oxidant 4,4'-dipyridyl disulfide. (PubMed id 17253982)9 Lopez-Mirabal H.R....Winther J.R. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 219409 HGNC: 20374 AceView: GSH1 Ensembl:ENSG00000169840 euGenes: HUgn219409
    ECgene: GSX1 H-InvDB: GSX1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GSX1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GSX1 gene:
    Search GeneIP for patents involving GSX1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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