Aliases for GSTO2 Gene
External Ids for GSTO2 Gene
Previous GeneCards Identifiers for GSTO2 Gene
The protein encoded by this gene is an omega class glutathione S-transferase (GST). GSTs are involved in the metabolism of xenobiotics and carcinogens. Four transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
GeneCards Summary for GSTO2 Gene
GSTO2 (Glutathione S-Transferase Omega 2) is a Protein Coding gene. Diseases associated with GSTO2 include parkinson disease, late-onset. Among its related pathways are Metabolism of xenobiotics by cytochrome P450 and Glutathione metabolism. GO annotations related to this gene include oxidoreductase activity and protein disulfide oxidoreductase activity. An important paralog of this gene is GSTO1.
UniProtKB/Swiss-Prot for GSTO2 Gene
Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).