Aliases for GSS Gene
External Ids for GSS Gene
Previous GeneCards Identifiers for GSS Gene
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq, Jul 2008]
GeneCards Summary for GSS Gene
GSS (Glutathione Synthetase) is a Protein Coding gene. Diseases associated with GSS include Glutathione Synthetase Deficiency and Hemolytic Anemia Due To Glutathione Synthetase Deficiency. Among its related pathways are Glutathione metabolism and Phase II conjugation. GO annotations related to this gene include protein homodimerization activity and peptide binding.