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Aliases for GSN Gene

Aliases for GSN Gene

  • Gelsolin 2 3 3 5
  • Actin-Depolymerizing Factor 3 4
  • Brevin 3 4
  • AGEL 3 4
  • ADF 3 4
  • Gelsolin (Amyloidosis, Finnish Type) 2
  • Amyloidosis, Finnish Type 2

External Ids for GSN Gene

Previous GeneCards Identifiers for GSN Gene

  • GC09P115166
  • GC09P115708
  • GC09P117515
  • GC09P119438
  • GC09P119406
  • GC09P121109
  • GC09P123070
  • GC09P123971
  • GC09P093648

Summaries for GSN Gene

Entrez Gene Summary for GSN Gene

  • The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for GSN Gene

GSN (Gelsolin) is a Protein Coding gene. Diseases associated with GSN include Amyloidosis, Finnish Type and Amyloidosis. Among its related pathways are Apoptosis and survival Caspase cascade and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include calcium ion binding and protein domain specific binding. An important paralog of this gene is SCIN.

UniProtKB/Swiss-Prot for GSN Gene

  • Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Gene Wiki entry for GSN Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GSN Gene

Genomics for GSN Gene

Regulatory Elements for GSN Gene

Enhancers for GSN Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09G121267 1.6 FANTOM5 ENCODE dbSUPER 17 +62.6 62649 6.1 PKNOX1 ARID4B SIN3A ZNF48 ZNF121 ZNF263 SP3 REST TBX21 CBX8 GSN RAB14 STOM LOC102723324 C5 PSMD5-AS1 ENSG00000239593 LOC645482
GH09G121275 2 FANTOM5 Ensembl ENCODE dbSUPER 12.4 +75.0 75012 15.3 MLX CREB3L1 ZFP64 DMAP1 SLC30A9 ZNF143 ZNF263 SP3 MEF2D SSRP1 GSN GGTA1P C5 STOM LOC102723324 PSMD5-AS1 GSN-AS1 ENSG00000239593
GH09G121350 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11 +150.3 150265 16.3 PKNOX1 SIN3A FEZF1 YY1 TCF12 GATA2 CBX5 ZNF143 FOS DEK RAB14 GGTA1P GSN GSN-AS1 ENSG00000239593 PSMD5-AS1 TRAF1 LOC102723324 PIR41790
GH09G121233 1.5 Ensembl ENCODE dbSUPER 12.7 +26.9 26922 2.4 HDGF ATF1 ARNT ZFP64 FEZF1 TCF12 ELK1 ZNF207 FOS KLF13 GSN ENSG00000239593 GSN-AS1 LOC102723324 STOM C5 PSMD5-AS1 LOC645482 RAB14
GH09G121293 1.5 Ensembl ENCODE dbSUPER 12 +89.7 89735 7.3 HNRNPUL1 FOXA2 MLX ARID4B ZNF48 SLC30A9 ZNF143 SP3 SP5 ZHX2 GSN GGTA1P STOM LOC102723324 C5 PSMD5-AS1 LOC105376256 GSN-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GSN on UCSC Golden Path with GeneCards custom track

Genomic Location for GSN Gene

Chromosome:
9
Start:
121,207,794 bp from pter
End:
121,332,844 bp from pter
Size:
125,051 bases
Orientation:
Plus strand

Genomic View for GSN Gene

Genes around GSN on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GSN Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GSN Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GSN Gene

Proteins for GSN Gene

  • Protein details for GSN Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P06396-GELS_HUMAN
    Recommended name:
    Gelsolin
    Protein Accession:
    P06396
    Secondary Accessions:
    • A2A418
    • A8MUD1
    • A8MYN7
    • B7Z373
    • B7Z5V1
    • F5H1A8
    • Q5T0I2
    • Q8WVV7

    Protein attributes for GSN Gene

    Size:
    782 amino acids
    Molecular mass:
    85698 Da
    Quaternary structure:
    • Binds to actin and to fibronectin. Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X. Interacts with the inactive form of EIF2AK2/PKR (By similarity).

    Three dimensional structures from OCA and Proteopedia for GSN Gene

    Alternative splice isoforms for GSN Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GSN Gene

Post-translational modifications for GSN Gene

  • Phosphorylation on Tyr-86, Tyr-409, Tyr-465, Tyr-603 and Tyr-651 in vitro is induced in presence of phospholipids.
  • Ubiquitination at posLast=584584
  • Glycosylation at isoforms=35 and posLast=431431
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for GSN (Gelsolin)

No data available for DME Specific Peptides for GSN Gene

Domains & Families for GSN Gene

Gene Families for GSN Gene

Graphical View of Domain Structure for InterPro Entry

P06396

UniProtKB/Swiss-Prot:

GELS_HUMAN :
  • Belongs to the villin/gelsolin family.
Family:
  • Belongs to the villin/gelsolin family.
genes like me logo Genes that share domains with GSN: view

Function for GSN Gene

Molecular function for GSN Gene

GENATLAS Biochemistry:
gelsolin,actin filaments severing and capping protein,expressed in macrophages,platelets,plasma,with homology to villin,Ca2+ and polyphosphoinositide 4,5-biphosphate (PIP2)-regulated,implicated in actin remodeling in growing and in apoptotic cells,cleaved by CASP3 to form a potential effector of morphologic change during apoptosis
UniProtKB/Swiss-Prot Function:
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.

Gene Ontology (GO) - Molecular Function for GSN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003779 actin binding IDA,IEA 18266911
GO:0005509 calcium ion binding IEA,IMP 14596804
GO:0005515 protein binding IPI 10793131
GO:0019904 protein domain specific binding IPI 23729654
GO:0045159 myosin II binding IPI 23325791
genes like me logo Genes that share ontologies with GSN: view
genes like me logo Genes that share phenotypes with GSN: view

Human Phenotype Ontology for GSN Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for GSN Gene

MGI Knock Outs for GSN:

Animal Model Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for GSN

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for GSN Gene

Localization for GSN Gene

Subcellular locations from UniProtKB/Swiss-Prot for GSN Gene

Isoform 2: Cytoplasm, cytoskeleton.
Isoform 1: Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GSN gene
Compartment Confidence
plasma membrane 5
extracellular 5
cytoskeleton 5
cytosol 5
nucleus 2
endoplasmic reticulum 2
golgi apparatus 2
mitochondrion 1
lysosome 1

Gene Ontology (GO) - Cellular Components for GSN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001726 ruffle IEA --
GO:0002102 podosome IDA 24236012
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IDA 14596804
GO:0005634 colocalizes_with nucleus IDA 23729654
genes like me logo Genes that share ontologies with GSN: view

Pathways & Interactions for GSN Gene

genes like me logo Genes that share pathways with GSN: view

SIGNOR curated interactions for GSN Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for GSN Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006911 phagocytosis, engulfment IEA,ISS --
GO:0006915 apoptotic process IEA --
GO:0007568 aging IEA --
GO:0008154 actin polymerization or depolymerization IEA --
GO:0010628 positive regulation of gene expression IMP 22952982
genes like me logo Genes that share ontologies with GSN: view

Drugs & Compounds for GSN Gene

(32) Drugs for GSN Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Latrunculin A Experimental Pharma Target Inhibitor of actin assembly and polymerization 0
calcium Nutra 0

(47) Additional Compounds for GSN Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with GSN: view

Transcripts for GSN Gene

Unigene Clusters for GSN Gene

Gelsolin:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for GSN

Alternative Splicing Database (ASD) splice patterns (SP) for GSN Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14a · 14b · 14c ^ 15a · 15b ·
SP1: - - - - - - - - - - - - - - - - - - - - -
SP2: - - - - - - - - - - - - - - - - - - -
SP3: - - - -
SP4:
SP5: - - - - - - - - - - -
SP6: - - - - - - - - - - - - - - - - - -
SP7: - - - - - - - - - - - - - - - -
SP8: - - - - - - - - - - - - - - - - - -
SP9: - - - - - - - - - - - - - - - -
SP10: - - - - - - - - - - - - - - - - - - -
SP11: - - - - - - - - - - - - - - - - - -
SP12:
SP13:
SP14: - - - - - - - - - - - - - - - - - - -
SP15: - - - - - - - - - - - - - - - -
SP16: - - - - - -
SP17: - - - - - - - - - - - - - - - - - - -
SP18: - - - - - - - - - - - - - - - - - - - -
SP19: - - - - - - - - - - - - - - - - - - - -
SP20: - - - - - - - - - - - - - - - - - - - -
SP21: - - - - - - - - - - - - - - - - -
SP22: - - - - - - - - - - - - - - - - - -
SP23: - - - - - - - - - - - - - - - - - - - - -
SP24: - - - - - - - - - - - - - - - - - -
SP25: - - - - - - - - - - - - - - - - -
SP26: - - - - - - - - - - - - - - - - - -
SP27:
SP28: - - - - - - - - - - - - - - - - - - -
SP29: - - - - - - - - - - - - - - - - - - - -
SP30: - - - - - - - - - - - - - - - -
SP31: - - - - - - - - - - - - -
SP32: - - - - - - - - - - - - - -
SP33: - - - - - - - -
SP34: - - - - - - - - -
SP35: - - - - - - - - - - - - - - - - - -
SP36: - - - - - - - - - - - - - - - - - - -
SP37: - - - - - - - - - - - - - - - - - -
SP38:
SP39: - - - - - - - - - - - - -
SP40:
SP41:
SP42:
SP43: -
SP44:

ExUns: 15c · 15d · 15e ^ 16 ^ 17a · 17b · 17c · 17d · 17e · 17f · 17g ^ 18a · 18b · 18c · 18d · 18e ^ 19a · 19b ^ 20a · 20b · 20c · 20d ^ 21a · 21b · 21c · 21d ^
SP1: - - -
SP2: - - -
SP3: - - -
SP4: -
SP5:
SP6: -
SP7: -
SP8: -
SP9:
SP10: -
SP11: - -
SP12: - - - - - -
SP13:
SP14: - - - - - - - - - - - - -
SP15: -
SP16: -
SP17:
SP18: -
SP19: - - - - -
SP20: - - - - - - - - - - - - - -
SP21:
SP22:
SP23: - -
SP24:
SP25:
SP26:
SP27:
SP28: - - - - -
SP29: - - - - - - - - - - - - - - - - - - - - - - - - - -
SP30:
SP31:
SP32: -
SP33: -
SP34: -
SP35:
SP36:
SP37:
SP38:
SP39:
SP40:
SP41: - -
SP42:
SP43:
SP44:

ExUns: 22 ^ 23 ^ 24a · 24b · 24c ^ 25 ^ 26 ^ 27a · 27b · 27c ^ 28 ^ 29a · 29b ^ 30a · 30b ^ 31 ^ 32a · 32b ^ 33a · 33b · 33c
SP1: - - - - -
SP2: - - - - -
SP3: - - - - -
SP4: - - - -
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13: - - -
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:
SP26:
SP27: - - -
SP28:
SP29:
SP30:
SP31:
SP32:
SP33:
SP34:
SP35:
SP36:
SP37:
SP38:
SP39:
SP40:
SP41:
SP42: -
SP43:
SP44:

Relevant External Links for GSN Gene

GeneLoc Exon Structure for
GSN
ECgene alternative splicing isoforms for
GSN

Expression for GSN Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GSN Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GSN Gene

This gene is overexpressed in Heart - Atrial Appendage (x4.6).

Protein differential expression in normal tissues from HIPED for GSN Gene

This gene is overexpressed in Serum (7.8) and Platelet (6.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for GSN Gene



NURSA nuclear receptor signaling pathways regulating expression of GSN Gene:

GSN

SOURCE GeneReport for Unigene cluster for GSN Gene:

Hs.522373

mRNA Expression by UniProt/SwissProt for GSN Gene:

P06396-GELS_HUMAN
Tissue specificity: Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells.

Evidence on tissue expression from TISSUES for GSN Gene

  • Nervous system(5)
  • Intestine(4.9)
  • Pancreas(4.8)
  • Blood(4.7)
  • Skin(4.7)
  • Liver(4.5)
  • Eye(4.4)
  • Kidney(4.4)
  • Heart(4)
  • Lung(4)
  • Muscle(3.7)
  • Stomach(3.6)
  • Adrenal gland(2.7)
  • Spleen(2.4)
  • Bone marrow(2.3)
  • Gall bladder(2.2)
  • Lymph node(2.1)
  • Thyroid gland(2.1)
  • Bone(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for GSN Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • urinary
Organs:
Head and neck:
  • ear
  • eye
  • face
  • head
  • jaw
  • mandible
  • maxilla
  • mouth
  • nose
  • skull
  • tongue
Thorax:
  • heart
  • heart valve
  • lung
Abdomen:
  • kidney
Pelvis:
  • ureter
  • urinary bladder
Limb:
  • lower limb
  • upper limb
General:
  • blood
  • blood vessel
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
genes like me logo Genes that share expression patterns with GSN: view

No data available for Protein tissue co-expression partners for GSN Gene

Orthologs for GSN Gene

This gene was present in the common ancestor of animals.

Orthologs for GSN Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GSN 34 35
  • 99.57 (n)
cow
(Bos Taurus)
Mammalia GSN 34 35
  • 91.24 (n)
dog
(Canis familiaris)
Mammalia GSN 34 35
  • 89.42 (n)
rat
(Rattus norvegicus)
Mammalia Gsn 34
  • 89.24 (n)
mouse
(Mus musculus)
Mammalia Gsn 34 16 35
  • 88.98 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 83 (a)
OneToMany
-- 35
  • 74 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia GSN 35
  • 81 (a)
OneToOne
chicken
(Gallus gallus)
Aves GSN 34 35
  • 73.41 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 39 (a)
ManyToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia gsn 34
  • 70.24 (n)
Str.1282 34
African clawed frog
(Xenopus laevis)
Amphibia LOC397895 34
zebrafish
(Danio rerio)
Actinopterygii gsna 34 35
  • 68.68 (n)
gsnb 35
  • 67 (a)
OneToMany
-- 34
fruit fly
(Drosophila melanogaster)
Insecta Gel 36
  • 37 (a)
worm
(Caenorhabditis elegans)
Secernentea K06A4.3 36
  • 38 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6001 35
  • 48 (a)
OneToMany
Species where no ortholog for GSN was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GSN Gene

ENSEMBL:
Gene Tree for GSN (if available)
TreeFam:
Gene Tree for GSN (if available)

Paralogs for GSN Gene

Paralogs for GSN Gene

(7) SIMAP similar genes for GSN Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with GSN: view

Variants for GSN Gene

Sequence variations from dbSNP and Humsavar for GSN Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs121909715 Pathogenic, Amyloidosis 5 (AMYL5) [MIM:105120], Amyloidosis 5 (AMYL5) [MIM:105120] 121,310,819(+) ATGGC(A/G/T)ACTGC nc-transcript-variant, upstream-variant-2KB, reference, missense
VAR_036337 A breast cancer sample
VAR_036338 A breast cancer sample
VAR_036339 A breast cancer sample
rs116185403 Likely benign 121,321,364(+) ACTAC(C/T)GCCAT nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for GSN Gene

Variant ID Type Subtype PubMed ID
esv3306098 CNV mobile element insertion 20981092
esv3437700 CNV insertion 20981092
nsv474372 CNV novel sequence insertion 20440878

Variation tolerance for GSN Gene

Residual Variation Intolerance Score: 93.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.29; 85.17% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GSN Gene

Human Gene Mutation Database (HGMD)
GSN
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GSN

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GSN Gene

Disorders for GSN Gene

MalaCards: The human disease database

(31) MalaCards diseases for GSN Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
amyloidosis, finnish type
  • finnish type amyloidosis
amyloidosis
  • amyloid disease
familial amyloidosis, finnish type
  • amyloidosis, meretoja type
hereditary amyloidosis
  • amyloidosis hereditary
lattice corneal dystrophy
  • familial amyloid neuropathy, finnish type
- elite association - COSMIC cancer census association via MalaCards
Search GSN in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

GELS_HUMAN
  • Amyloidosis 5 (AMYL5) [MIM:105120]: A hereditary generalized amyloidosis due to gelsolin amyloid deposition. It is typically characterized by cranial neuropathy and lattice corneal dystrophy. Most patients have modest involvement of internal organs, but severe systemic disease can develop in some individuals causing peripheral polyneuropathy, amyloid cardiomyopathy, and nephrotic syndrome leading to renal failure. {ECO:0000269 PubMed:1338910, ECO:0000269 PubMed:2176481}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for GSN

Genetic Association Database (GAD)
GSN
Human Genome Epidemiology (HuGE) Navigator
GSN
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GSN
genes like me logo Genes that share disorders with GSN: view

No data available for Genatlas for GSN Gene

Publications for GSN Gene

  1. Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach. (PMID: 10210201) De Corte V. … Vandekerckhove J. (Protein Sci. 1999) 3 4 22 64
  2. Functional consequences of disulfide bond formation in gelsolin. (PMID: 9003812) Allen P.G. (FEBS Lett. 1997) 3 4 22 64
  3. Spectroscopic studies of a phosphoinositide-binding peptide from gelsolin: behavior in solutions of mixed solvent and anionic micelles. (PMID: 8599675) Xian W. … Braunlin W.H. (Biophys. J. 1995) 3 4 22 64
  4. Finnish type of familial amyloidosis: cosegregation of Asp187----Asn mutation of gelsolin with the disease in three large families. (PMID: 1652889) Hiltunen T. … Peltonen L. (Am. J. Hum. Genet. 1991) 2 3 22 64
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64

Products for GSN Gene

  • Addgene plasmids for GSN