Aliases for GSG2 Gene
External Ids for GSG2 Gene
Previous GeneCards Identifiers for GSG2 Gene
GeneCards Summary for GSG2 Gene
GSG2 (Germ Cell Associated 2, Haspin) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein serine/threonine kinase activity.
UniProtKB/Swiss-Prot for GSG2 Gene
Serine/threonine-protein kinase that phosphorylates histone H3 at Thr-3 (H3T3ph) during mitosis. This positions and activates AURKB and other components of the chromosomal passenger complex (CPC) at centromeres to ensure proper chromatid cohesion, metaphase alignment and normal progression through the cell cycle.
Haspin (germ cell associated 2), EC 18.104.22.168, is a serine/threonine kinase that has a critical function in mitosis. The enzyme phosphorylates threonine-3 on histone H3 during mitosis.