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Aliases for GSE1 Gene

Aliases for GSE1 Gene

  • Gse1 Coiled-Coil Protein 2 3
  • KIAA0182 2 3 4
  • Genetic Suppressor Element 1 2 3
  • Gse1 Coiled-Coil Protein Homolog (Mouse) 2
  • Gse1 Coiled-Coil Protein Homolog 3

External Ids for GSE1 Gene

Previous Symbols for GSE1 Gene

  • KIAA0182

Summaries for GSE1 Gene

GeneCards Summary for GSE1 Gene

GSE1 (Gse1 Coiled-Coil Protein) is a Protein Coding gene.

Gene Wiki entry for GSE1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GSE1 Gene

Genomics for GSE1 Gene

Genomic Location for GSE1 Gene

Start:
85,169,546 bp from pter
End:
85,676,206 bp from pter
Size:
506,661 bases
Orientation:
Plus strand

Genomic View for GSE1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GSE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GSE1 Gene

No data available for Regulatory Elements for GSE1 Gene

Proteins for GSE1 Gene

  • Protein details for GSE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q14687-GSE1_HUMAN
    Recommended name:
    Genetic suppressor element 1
    Protein Accession:
    Q14687
    Secondary Accessions:
    • D3DUM4
    • Q8IY61
    • Q96GA4
    • Q9BW09

    Protein attributes for GSE1 Gene

    Size:
    1217 amino acids
    Molecular mass:
    136164 Da
    Quaternary structure:
    • May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I
    SequenceCaution:
    • Sequence=BAA11499.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for GSE1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GSE1 Gene

Proteomics data for GSE1 Gene at MOPED

Post-translational modifications for GSE1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GSE1 Gene

Domains for GSE1 Gene

Protein Domains for GSE1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with GSE1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for GSE1 Gene

Function for GSE1 Gene

Gene Ontology (GO) - Molecular Function for GSE1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with GSE1: view
genes like me logo Genes that share phenotypes with GSE1: view

miRNA for GSE1 Gene

miRTarBase miRNAs that target GSE1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for GSE1 Gene

Localization for GSE1 Gene

No data available for Gene Ontology (GO) - Cellular Components for GSE1 Gene

Pathways for GSE1 Gene

SuperPathways for GSE1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GSE1 Gene

None

No data available for Pathways by source for GSE1 Gene

Transcripts for GSE1 Gene

Unigene Clusters for GSE1 Gene

Gse1 coiled-coil protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GSE1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15
SP1:
SP2: - - - - -
SP3:
SP4: -
SP5:
SP6:
SP7:

Relevant External Links for GSE1 Gene

GeneLoc Exon Structure for
GSE1
ECgene alternative splicing isoforms for
GSE1

Expression for GSE1 Gene

mRNA expression in normal human tissues for GSE1 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for GSE1 Gene

SOURCE GeneReport for Unigene cluster for GSE1 Gene Hs.461647

genes like me logo Genes that share expressions with GSE1: view

Orthologs for GSE1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GSE1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GSE1 36
  • 97.58 (n)
  • 97.85 (a)
GSE1 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GSE1 37
  • 89 (a)
OneToOne
KIAA0182 36
  • 86.08 (n)
  • 87.19 (a)
dog
(Canis familiaris)
Mammalia GSE1 37
  • 91 (a)
OneToOne
KIAA0182 36
  • 88.76 (n)
  • 91.11 (a)
mouse
(Mus musculus)
Mammalia Gse1 36
  • 84.19 (n)
  • 88.08 (a)
Gse1 16
Gse1 37
  • 89 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GSE1 37
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GSE1 37
  • 81 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gse1 36
  • 84.47 (n)
  • 88.06 (a)
chicken
(Gallus gallus)
Aves GSE1 37
  • 76 (a)
OneToOne
KIAA0182 36
  • 74.77 (n)
  • 75.66 (a)
lizard
(Anolis carolinensis)
Reptilia GSE1 37
  • 75 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.1433 36
tropical clawed frog
(Silurana tropicalis)
Amphibia gse1 36
  • 61.97 (n)
  • 61.68 (a)
Str.17615 36
zebrafish
(Danio rerio)
Actinopterygii gse1 36
  • 60.63 (n)
  • 59.76 (a)
gse1 37
  • 58 (a)
OneToOne
Species with no ortholog for GSE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GSE1 Gene

ENSEMBL:
Gene Tree for GSE1 (if available)
TreeFam:
Gene Tree for GSE1 (if available)

Paralogs for GSE1 Gene

Selected SIMAP similar genes for GSE1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with GSE1: view

No data available for Paralogs for GSE1 Gene

Variants for GSE1 Gene

Sequence variations from dbSNP and Humsavar for GSE1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs2028 -- 85,675,261(+) CGGTC(C/G)TTAGA utr-variant-3-prime
rs2029 -- 85,675,240(+) TGCAC(A/C/G)TGAAA utr-variant-3-prime
rs8571 -- 85,676,004(+) CATAC(A/G)CAGGT utr-variant-3-prime
rs9598 -- 85,673,312(+) TGCTT(C/T)AGCCT utr-variant-3-prime
rs11375 -- 85,672,963(+) GCAGC(A/G)ATGGG utr-variant-3-prime

Relevant External Links for GSE1 Gene

HapMap Linkage Disequilibrium report
GSE1
Human Gene Mutation Database (HGMD)
GSE1

No data available for Structural Variations from Database of Genomic Variants (DGV) for GSE1 Gene

Disorders for GSE1 Gene

No disorders were found for GSE1 Gene.

No data available for UniProtKB/Swiss-Prot for GSE1 Gene

Publications for GSE1 Gene

  1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8724849) Nagase T. … Nomura N. (DNA Res. 1996) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. (PMID: 16079794) Lee M.G. … Shiekhattar R. (Nature 2005) 3
  4. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for GSE1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate GSE1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for GSE1
    • Block miRNA regulation of GSE1 using miScript Target Protectors

    Sources for GSE1 Gene

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