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Aliases for GSE1 Gene

Aliases for GSE1 Gene

  • Gse1 Coiled-Coil Protein 2 3
  • KIAA0182 2 3 4
  • Gse1 Coiled-Coil Protein Homolog (Mouse) 2
  • Gse1 Coiled-Coil Protein Homolog 3
  • Genetic Suppressor Element 1 2
  • CTC-786C10.1 3

External Ids for GSE1 Gene

Previous HGNC Symbols for GSE1 Gene

  • KIAA0182

Previous GeneCards Identifiers for GSE1 Gene

  • GC16P085646

Summaries for GSE1 Gene

GeneCards Summary for GSE1 Gene

GSE1 (Gse1 Coiled-Coil Protein) is a Protein Coding gene.

Gene Wiki entry for GSE1 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GSE1 Gene

Genomics for GSE1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for GSE1 Gene

85,170,003 bp from pter
85,676,206 bp from pter
506,204 bases
Plus strand

Genomic View for GSE1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GSE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GSE1 Gene

No data available for Regulatory Elements for GSE1 Gene

Proteins for GSE1 Gene

  • Protein details for GSE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Genetic suppressor element 1
    Protein Accession:
    Secondary Accessions:
    • D3DUM4
    • Q8IY61
    • Q96GA4
    • Q9BW09

    Protein attributes for GSE1 Gene

    1217 amino acids
    Molecular mass:
    136164 Da
    Quaternary structure:
    • May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I
    • Sequence=BAA11499.2; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for GSE1 Gene


neXtProt entry for GSE1 Gene

Proteomics data for GSE1 Gene at MOPED

Post-translational modifications for GSE1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GSE1 Gene

Domains & Families for GSE1 Gene

Protein Domains for GSE1 Gene


Suggested Antigen Peptide Sequences for GSE1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GSE1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for GSE1 Gene

Function for GSE1 Gene

Gene Ontology (GO) - Molecular Function for GSE1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with GSE1: view
genes like me logo Genes that share phenotypes with GSE1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for GSE1 Gene

Localization for GSE1 Gene

Subcellular locations from

Jensen Localization Image for GSE1 Gene COMPARTMENTS Subcellular localization image for GSE1 gene
Compartment Confidence
mitochondrion 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GSE1 Gene

Pathways & Interactions for GSE1 Gene

SuperPathways for GSE1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GSE1 Gene


No data available for Pathways by source and SIGNOR curated interactions for GSE1 Gene

Drugs & Compounds for GSE1 Gene

No Compound Related Data Available

Transcripts for GSE1 Gene

Unigene Clusters for GSE1 Gene

Gse1 coiled-coil protein:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GSE1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GSE1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15
SP2: - - - - -
SP4: -

Relevant External Links for GSE1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GSE1 Gene

mRNA expression in normal human tissues for GSE1 Gene

Protein differential expression in normal tissues from HIPED for GSE1 Gene

This gene is overexpressed in Cervix (31.9), Placenta (18.2), and Monocytes (8.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GSE1 Gene

SOURCE GeneReport for Unigene cluster for GSE1 Gene Hs.461647

genes like me logo Genes that share expression patterns with GSE1: view

Protein tissue co-expression partners for GSE1 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GSE1 Gene

Orthologs for GSE1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GSE1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia KIAA0182 35
  • 86.08 (n)
  • 87.19 (a)
GSE1 36
  • 89 (a)
(Canis familiaris)
Mammalia KIAA0182 35
  • 88.76 (n)
  • 91.11 (a)
GSE1 36
  • 91 (a)
(Mus musculus)
Mammalia Gse1 35
  • 84.19 (n)
  • 88.08 (a)
Gse1 16
Gse1 36
  • 89 (a)
(Pan troglodytes)
Mammalia GSE1 35
  • 97.58 (n)
  • 97.85 (a)
GSE1 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Gse1 35
  • 84.47 (n)
  • 88.06 (a)
(Monodelphis domestica)
Mammalia GSE1 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia GSE1 36
  • 81 (a)
(Gallus gallus)
Aves KIAA0182 35
  • 74.77 (n)
  • 75.66 (a)
GSE1 36
  • 76 (a)
(Anolis carolinensis)
Reptilia GSE1 36
  • 75 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gse1 35
  • 61.97 (n)
  • 61.68 (a)
Str.17615 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.1433 35
(Danio rerio)
Actinopterygii gse1 35
  • 60.63 (n)
  • 59.76 (a)
gse1 36
  • 58 (a)
Species with no ortholog for GSE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GSE1 Gene

Gene Tree for GSE1 (if available)
Gene Tree for GSE1 (if available)

Paralogs for GSE1 Gene

(5) SIMAP similar genes for GSE1 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with GSE1: view

No data available for Paralogs for GSE1 Gene

Variants for GSE1 Gene

Sequence variations from dbSNP and Humsavar for GSE1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs2028 -- 85,675,261(+) CGGTC(C/G)TTAGA utr-variant-3-prime
rs2029 -- 85,675,240(+) TGCAC(A/C/G)TGAAA utr-variant-3-prime
rs8571 -- 85,676,004(+) CATAC(A/G)CAGGT utr-variant-3-prime
rs9598 -- 85,673,312(+) TGCTT(C/T)AGCCT utr-variant-3-prime
rs11375 -- 85,672,963(+) GCAGC(A/G)ATGGG utr-variant-3-prime

Variation tolerance for GSE1 Gene

Residual Variation Intolerance Score: 19.28% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.84; 79.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GSE1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GSE1 Gene

Disorders for GSE1 Gene

Relevant External Links for GSE1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with GSE1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GSE1 Gene

Publications for GSE1 Gene

  1. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8724849) Nagase T. … Nomura N. (DNA Res. 1996) 2 67
  2. Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h. (PMID: 8786132) Chiang P.-W. … Kurnit D.M. (Genomics 1996) 2 67
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  4. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 67
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67

Products for GSE1 Gene

Sources for GSE1 Gene

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