Aliases for GRXCR2 Gene
External Ids for GRXCR2 Gene
Previous GeneCards Identifiers for GRXCR2 Gene
This gene encodes a protein containing a glutaredoxin domain, which functions in protein S-glutathionylation. A mutation in this gene was found in a family with autoosomal recessive nonsyndromic sensorineural deafness-101. [provided by RefSeq, Jun 2014]
GeneCards Summary for GRXCR2 Gene
GRXCR2 (Glutaredoxin And Cysteine Rich Domain Containing 2) is a Protein Coding gene. Diseases associated with GRXCR2 include deafness, autosomal recessive 101 and autosomal recessive non-syndromic sensorineural deafness type dfnb. GO annotations related to this gene include unfolded protein binding and heat shock protein binding. An important paralog of this gene is GRXCR1.
UniProtKB/Swiss-Prot for GRXCR2 Gene
Could play a role in maintaining cochlear stereocilia bundles that are involved in sound detection.