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CXCL3 Gene

protein-coding GIFtS: 56

GC04M075121

chemokine (C-X-C motif) ligand 3
(Previous name: GRO3 oncogene )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: GRO3)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CINC-2b ^¹, ²
GRO-gamma ^³
GRO-gamma(1-73) ^³
GRO3 ^², ³, ⁵
GROG ^³
GROg ^¹, ²
MIP-2b ^¹, ²
MIP2-beta ^³
MIP2B ^², ⁵
SCYB3 ^¹, ², ³

Descriptions
GRO3 oncogene ^¹, ²
Growth-regulated protein gamma ^³
MGSA gamma ^²
Macrophage inflammatory protein 2-beta ^³
chemokine (C-X-C motif) ligand 3 ^²
melanoma growth stimulatory activity gamma ^²

External Ids
HGNC: 4604¹
Entrez Gene: 2921²
UniProtKB: P19876³
Ensembl: ENSG00000163734⁷

Search outside databases for aliases for CXCL3 gene

Previous GC identifers: GC04M074891 GC04M075141 GC04M075302 GC04M075368 GC04M075267

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CXCL3_HUMAN, P19876

Function: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a

role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro,

the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic

granulocytes

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CXCL3 gene

Entrez Gene cytogenetic band: 4q21 Ensembl cytogenetic band: 4q13.3 HGNC cytogenetic band: 4q21

CXCL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 4 GeneLoc Exon Structure

GeneLoc location for GC04M075121: (about GC identifiers)

Start:	75,121,170 bp from pter
End:	75,123,354 bp from pter
Size:	2,185 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000004.10 NT_006216.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CXCL3_HUMAN, P19876 (See protein sequence)

Recommended Name: C-X-C motif chemokine 3 precursor

Size: 107 amino acids; 11342 Da

Subcellular location: Secreted

Secondary accessions: Q4W5H9

Post-translational modifications:

N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from

peripheral blood monocytes¹

REFSEQ proteins: NP_002081.2

ENSEMBL proteins:

ENSP00000296026

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for CXCL3 (CXCL3/GRO gamma/CINC-2/DCIP-1)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GRO gamma)
	Human Recombinant Proteins from Abnova (CXCL3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005615	extracellular space	IDA	10095777

About this table

Antibodies for CXCL3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for CXCL3
	R&D Systems Antibodies for CXCL3 (CXCL3/GRO gamma/CINC-2/DCIP-1)
	Antibodies from Abcam (GRO gamma), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for CXCL3

Assays for CXCL3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P19876

ProtoNet protein and cluster: P19876

1 Blocks protein family: IPB002473 Interleukin-8 signature

UniProtKB/Swiss-Prot: CXCL3_HUMAN, P19876

Similarity: Belongs to the intercrine alpha (chemokine CxC) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CXCL3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002090

Applied Biosystems Silencer® siRNAs for CXCL3

Sigma-Aldrich siRNA for CXCL3

Sigma-Aldrich shRNA Panels and shRNA for CXCL3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CXCL3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002090
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002090
untagged cDNA clone in CMV expression vector: NM_002090

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002090

UniProtKB/Swiss-Prot: CXCL3_HUMAN, P19876

Function: Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a

role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro,

the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic

granulocytes

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	ISS	--
GO:0008009	chemokine activity	ISS	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

3 Sigma-Aldrich "Your Favorite Gene" Pathways for CXCL3 (Your Favorite Gene powered by Ingenuity)

Hepatic Fibrosis / Hepatic Stellate Cell Activation
Glucocorticoid Receptor Signaling
Airway Pathology in Chronic Obstructive Pulmonary Disease

GeneDecks CXCL3 for the pathways selected above

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5/29 Interacting proteins for CXCL3 (ENSP00000296026³) via UniProtKB, MINT, and/or STRING (see all 29 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
IL8RB	ENSP00000319635³	STRING (score=.992)
FGF18	ENSP00000274625³	STRING (score=.928)
IL8	ENSP00000306512³	STRING (score=.91)
CXCL5	ENSP00000296027³	STRING (score=.907)
CXCL6	ENSP00000226317³	STRING (score=.907)

About this table

4 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006935	chemotaxis	IEA	--
GO:0006954	inflammatory response	IEA	--
GO:0006955	immune response	IEA	--
GO:0030593	neutrophil chemotaxis	ISS	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for CXCL3
5 Novoseek chemical compound relationships for CXCL3 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
grogamma	98.43	17	8702798 (5), 15832427 (2), 9553055 (2), 10695618 (1) (see all 8)
grobeta	96.16	15	8702798 (5), 15832427 (2), 9553055 (2), 10695618 (1) (see all 6)
groalpha	92.20	9	8702798 (2), 10695618 (1), 9054580 (1), 9553055 (1) (see all 5)
rantes	66.45	7	7682242 (2), 15832427 (1), 11001915 (1), 11808935 (1) (see all 6)
calcium	1.83	4	10095777 (1), 8340371 (1), 8702798 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CXCL3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002090

Sigma-Aldrich siRNA for CXCL3

Sigma-Aldrich shRNA Panels and shRNA for CXCL3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002090

REFSEQ mRNAs for CXCL3 gene:

NM_002090.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002090

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002090
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002090
                                 untagged cDNA clone in CMV expression vector: NM_002090

Additional cDNA sequence:

AK307064.1 AK311367.1 BC016308.1 BC065743.1 CR591181.1 M36821.1 X53800.1

3 DOTS entries:

DT.105208 DT.40257611 DT.97783873

24/34 AceView cDNA sequences (see all 34 ):

CD743042 BM128087 BU626899 BM128099 CD370075 CR591181 AI829424 X53800

BC065743 BI832837 BC016308 BV192573 BM828712 CB128389 BG570567 BX352546

T29169 CD520079 CA309305 BQ215959 CA748708 BX390861 CB129465 CA309555

highest scoring ESTs for CXCL3:

M36821 BC016308 BC065743 BG506634 BM828712 BQ215959 BX384694 CA309305 CB128389 CB129465

Unigene Cluster for CXCL3:

Chemokine (C-X-C motif) ligand 3

Hs.89690 [show with all ESTs]

Unigene Representative Sequence: AK311367

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000296026

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CXCL3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CXCL3

¹ / ² / ³

3 probe-sets matching CXCL3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34022_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	M36821	1.00	1.00	1.00	1
207850_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002090	0.60	1.00	0.82	1
207850_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CXCL3 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATAATAAAAG

SOURCE GeneReport for Unigene cluster: Hs.89690
Expression variation in blood from EXPOLDB for CXCL3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CXCL3 gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	CXCL3¹	--	chemokine (C-X-C motif) ligand 3	97.51(n) 96.26(a)	461255 XM_517228.2 XP_517228.2
rat (Rattus norvegicus)	Cxcl2¹	--	chemokine (C-X-C motif) ligand 2	71.04(n) 58.59(a)	114105 NM_053647.1 NP_446099.1
mouse (Mus musculus)	Cxcl3⁵ Cxcl2¹	5⁵	chemokine (C-X-C motif) ligand 3⁵ chemokine (C-X-C motif) ligand 2¹	74.07(n)¹ 64.65(a)¹	20310¹ NM_009140.2¹ NP_033166.1¹ AK144158⁵ AK150314⁵ (see all 12)

About this table Species with no ortholog for CXCL3

ENSEMBL Gene Tree for CXCL3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CXCL3 gene

PF4² PPBP² CXCL1² PF4V1² CXCL6² CXCL5² CXCL2² IL8²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/22 NCBI SNPs in CXCL3 are shown (see all 22 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 21)

AB	SNP ID	Valid	Chr 4 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs352043^1,2	A,H	75123185(-)	`GGCCCA/GCGCCA`	1	H/R	mis¹ ese³		3		EU EA	298
--	rs13150258^1,2	A	75121528(+)	`TATGGC/TCTCCC`	1	--	ut3¹ ese³		0	--	--	--	--
	rs370655^1,2	A,C,F,H	75121998(-)	`ATAGAA/GGGCAG`	1	--	int¹		5		MN EU EA WA	604
	rs181272^1,2	C,F,H	75122228(-)	`TCAACA/Gttatt`	1	--	int¹		9		NS EU EA WA	526
--	rs55826131^1,2	--	75120734(+)	`TTTTT-/TAATAT`	1	--	ng5¹		0	--	--	--	--
--	rs1051754^1,2	--	75121391(-)	`tttttA/Taaaaa`	1	--	ut3¹		0	--	--	--	--
--	rs72501281^1,2	--	75123230(-)	`CTTCCG/TCTCCT`	1	--	ut5¹		0	--	--	--	--
--	rs4694662^1,2	--	75121147(+)	`AAGAAG/TTTTTT`	1	--	ng5¹		0	--	--	--	--
--	rs33952565^1,2	--	75120735(+)	`TTTTA-/TATATC`	1	--	ng5¹		0	--	--	--	--
--	rs71788353^1,2	--	75121392(+)	`TTTTT-/AAAAAA`	1	--	ut3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for CXCL3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 139111

6 Novoseek disease relationships for CXCL3 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
osteosarcoma	39.59	1	18606014 (1)
necrosis	37.66	2	11001915 (1), 9277410 (1)
colon carcinoma	33.65	2	15787094 (1)
inflammation	25.37	1	9553055 (1)
tumors	20.98	3	10095777 (1), 11001915 (1), 9277410 (1)
melanoma	18.19	1	2201751 (1)

About this table

Human Genome Epidemiology Navigator: CXCL3 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/44 PubMed articles for CXCL3 gene (see all 44 ):

Identification of three related human GRO genes encoding cytokine functions. (PubMed id 2217207)^{2, 3, 4} Haskill S.... Sager R. (1990)
Isolation of the CXC chemokines ENA-78, GRO alpha and GRO gamma from tumor cells and leukocytes reveals NH2-terminal heterogeneity. Functional comparison of different natural isoforms. (PubMed id 10095777)^{1, 3, 4} Wuyts A.... Van Damme J. (1999)
Cloning and characterization of cDNAs for murine macrophage inflammatory protein 2 and its human homologues. (PubMed id 2201751)^{1, 3, 4} Tekamp-Olson P.... Cerami A. (1990)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{3, 4} Zhang Z. and Henzel W.J. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The CXC chemokines growth-regulated oncogene (GRO) alpha, GRObeta, GROgamma, neutrophil-activating peptide-2, and epithelial cell-derived neutrophil-activating peptide-78 are potent agonists for the type B, but not the type A, human interleukin-8 receptor. (PubMed id 8702798)^{1, 3} Ahuja S.K. and Murphy P.M. (1996)
Constitutive and stimulated MCP-1, GRO alpha, beta, and gamma expression in human airway epithelium and bronchoalveolar macrophages. (PubMed id 8166297)^{1, 3} Becker S....Haskill J.S. (1994)
Role of IKK and ERK pathways in intrinsic inflammation of cystic fibrosis airways. (PubMed id 17466952)^{1, 3} Verhaeghe C....Bours V. (2007)
Human hepatocytes express an array of proinflammatory cytokines after agonist stimulation or bacterial invasion. (PubMed id 9277410)^{1, 3} Rowell D.L....Kagnoff M.F. (1997)
Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. (PubMed id 19258923)³ Siezen C.L....Janssen R. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2921	HGNC: 4604	AceView: CXCL3	Ensembl:ENSG00000163734	euGenes: HUgn2921
ECgene: CXCL3	H-InvDB: CXCL3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CXCL3	Genetics and Cytogenetics in Oncology and Haematology
Wikipedia	http://en.wikipedia.org/wiki/CXCL3

Licensable Technologies for CXCL3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CXCL3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CXCL3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CXCL3		Antibodies for CXCL3
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CXCL3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CXCL3)
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	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (GRO gamma)
	Antibodies (GRO gamma)

Search OriGene for CXCL3

Search Tocris compounds for CXCL3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for CXCL3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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CXCL3 Gene at Home site.
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CXCL3 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for CXCL3

Summaries
for CXCL3

Genomic Location
for CXCL3

Proteins
for CXCL3

Protein Domains/
Families
for CXCL3

Gene Function
for CXCL3

Pathways & Interactions
for CXCL3

Drugs & Compounds
for CXCL3

Transcripts
for CXCL3

Expression
for CXCL3

Orthologs
for CXCL3

Paralogs
for CXCL3

SNPs/Variants
for CXCL3

Disorders & Mutations
for CXCL3

Medical News
for CXCL3

Publications
for CXCL3

Search for CXCL3

Genome Databases showing CXCL3

Other Databases showing CXCL3

Specialized Databases showing CXCL3

Licensable Technologies
for CXCL3

Services
for CXCL3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CXCL3 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor CXCL3

Summariesfor CXCL3

Genomic Locationfor CXCL3

Proteinsfor CXCL3

Protein Domains/Familiesfor CXCL3

Gene Functionfor CXCL3

Pathways & Interactionsfor CXCL3

Drugs & Compoundsfor CXCL3

Transcriptsfor CXCL3

Expression for CXCL3

Orthologsfor CXCL3

Paralogsfor CXCL3

SNPs/Variantsfor CXCL3

Disorders & Mutationsfor CXCL3

Medical Newsfor CXCL3

Publicationsfor CXCL3

Search for CXCL3

Genome Databases showing CXCL3

Other Databases showing CXCL3

Specialized Databases showing CXCL3

Licensable Technologiesfor CXCL3

Servicesfor CXCL3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CXCL3

Summaries
for CXCL3

Genomic Location
for CXCL3

Proteins
for CXCL3

Protein Domains/
Families
for CXCL3

Gene Function
for CXCL3

Pathways & Interactions
for CXCL3

Drugs & Compounds
for CXCL3

Transcripts
for CXCL3

Expression
for CXCL3

Orthologs
for CXCL3

Paralogs
for CXCL3

SNPs/Variants
for CXCL3

Disorders & Mutations
for CXCL3

Medical News
for CXCL3

Publications
for CXCL3

Licensable Technologies
for CXCL3

Services
for CXCL3