Aliases for GRK7 Gene
External Ids for GRK7 Gene
Previous HGNC Symbols for GRK7 Gene
Previous GeneCards Identifiers for GRK7 Gene
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. It is specifically expressed in the retina and the encoded protein has been shown to phosphorylate cone opsins and initiate their deactivation. [provided by RefSeq, Jul 2008]
GeneCards Summary for GRK7 Gene
GRK7 (G Protein-Coupled Receptor Kinase 7) is a Protein Coding gene. Diseases associated with GRK7 include Enhanced S-Cone Syndrome and Congenital Stationary Night Blindness. Among its related pathways are Metabolism of fat-soluble vitamins and Activation of cAMP-Dependent PKA. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is GRK4.
UniProtKB/Swiss-Prot for GRK7 Gene
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).