Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GRIP2 Gene

protein-coding   GIFtS: 50
GCID: GC03M014505

glutamate receptor interacting protein 2

 Explore 3 diseases affiliated with
GRIP2 via our new
 Human Malady Compendium 
Biological research products
for GRIP2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Glutamate Receptor Interacting Protein 21 2
KIAA17191 3
GRIP-22 3
Glutamate Receptor-Interacting Protein 22

External Ids:    HGNC: 238411   Entrez Gene: 808522   Ensembl: ENSG000001445967   UniProtKB: Q9C0E43   

Export aliases for GRIP2 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: GRIP2_HUMAN, Q9C0E4
Function: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator
of the trafficking of its binding partners at specific subcellular location in neurons (By similarity)

Gene Wiki entry for GRIP2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GRIP2 gene promoter:
         HOXA3   AML1a   Brachyury   POU2F1   POU2F1b   POU2F1a   FOXO1a   c-Jun   POU2F1c   FOXO1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for GRIP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRIP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p24-p23   Ensembl cytogenetic band:  3p25.1   HGNC cytogenetic band: 3p24-p23

GRIP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GRIP2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M014505:  view genomic region     (about GC identifiers)

Start:
14,530,619 bp from pter      End:
14,583,588 bp from pter
Size:
52,970 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GRIP2_HUMAN, Q9C0E4 (See protein sequence)
Recommended Name: Glutamate receptor-interacting protein 2  
Size: 1043 amino acids; 112501 Da
Subunit: Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with
GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR
Subcellular location: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity)
Sequence caution: Sequence=BAB21810.2; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for GRIP2:
1V62 (3D)        1X5R (3D)    
Secondary accessions: Q8TEH9 Q9H7H3
Alternative splicing: 3 isoforms:  Q9C0E4-1   Q9C0E4-2   Q9C0E4-3   (Incomplete sequence. Due to intron retention. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GRIP2: NX_Q9C0E4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9C0E4

  • GRIP2 Protein expression data from MOPED and PaxDb:    About this image 
    GRIP2 Protein Expression
    REFSEQ proteins: NP_001073892.2  Reactome Protein details: Q9C0E4
    Human Recombinant Protein Products for GRIP2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: GRIP2
    OriGene Custom Protein Services for GRIP2 
    GenScript Custom Purified and Recombinant Proteins Services for GRIP2
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GRIP2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol TAS--
    GO:0005886plasma membrane TAS--

    GRIP2 for ontologies           About GeneDecksing



    GRIP2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for GRIP2 
    GenScript Custom Superior Antibodies Services for GRIP2
    Abcam antibodies for GRIP2 
    Uscn Antibodies for GRIP2
    Search ThermoFisher Antibodies for GRIP2

    Assay Products for GRIP2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GRIP2
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for GRIP2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GRIP2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001478 PDZ

    Graphical View of Domain Structure for InterPro Entry Q9C0E4

    ProtoNet protein and cluster: Q9C0E4

    1 Blocks protein family: IPB001478 PDZ/DHR/GLGF domain

    UniProtKB/Swiss-Prot: GRIP2_HUMAN, Q9C0E4
    Domain: PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition
    motif of EFNB1. PDZ 7 mediates interaction with CSPG4 (By similarity)
    Similarity: Belongs to the GRIP2 family
    Similarity: Contains 7 PDZ (DHR) domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GRIP2_HUMAN, Q9C0E4
    Function: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator
    of the trafficking of its binding partners at specific subcellular location in neurons (By similarity)

    Phenotypes:
         4 GenomeRNAi human phenotypes for GRIP2:

     Elongated cells with protrusio  Increased G1 DNA content  Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Grip2):
     integument  limbs/digits/tail  nervous system  vision/eye 

    GRIP2 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Grip2tm1Rha for GRIP2
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GRIP2 

    miRNA
    Products:
        
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GRIP2
    8/77 QIAGEN miScript miRNA Assays for microRNAs that regulate GRIP2 (see all 77):
    hsa-miR-124* hsa-miR-3607-3p hsa-miR-300 hsa-miR-3916 hsa-miR-3150b-3p hsa-miR-92b hsa-miR-877 hsa-miR-4324
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRIP2 (see all 3)
    OriGene shRNA RFP: GRIP2
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRIP2
    Sirion Biotech Custom design and validation of potent shRNA sequences against GRIP2 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GRIP2
    Sirion Biotech Customized adenovirus for overexpression of GRIP2 
    Sirion Biotech Customized adenovirus for potent knockdown of GRIP2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: GRIP2 (NM_001080423)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRIP2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIP2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for GRIP2
    Search LifeMap BioReagents cell lines for GRIP2
    Sirion Biotech Customized stable knockdown cell line services for GRIP2 
    Sirion Biotech Customized inducible knockdown cell line services for GRIP2
    Sirion Biotech Customized stable overexpressing cell line services for GRIP2
    Sirion Biotech Customized inducible overexpressing cell line services for GRIP2

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIP2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Transmission across Chemical Synapses
    Transmission across Chemical Synapses1.00
    Neuronal System0.67
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell0.72
    2Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity1.00
    Trafficking of GluR2-containing AMPA receptors0.53
    Trafficking of AMPA receptors1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/6        Reactome Pathways for GRIP2 (see all 6)
        Trafficking of AMPA receptors
    Transmission across Chemical Synapses
    Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
    Neuronal System
    Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell



    GRIP2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GRIP2

    5/16 Interacting proteins for GRIP2 (Q9C0E42, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005192, 3MINT-8110431 I2D: score=3 
    GFI1BQ5VTD92, 3MINT-2876806 I2D: score=2 
    PRLHRP496832, 3MINT-1785769 I2D: score=1 
    CRKP461083I2D: score=2 
    CSPG4Q6UVK13I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007268synaptic transmission TAS--

    GRIP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GRIP2
    Search CenterWatch for drugs/clinical trials and news about GRIP2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GRIP2 gene: 
    NM_001080423.2  

    Unigene Cluster for GRIP2:

    Glutamate receptor interacting protein 2
    Hs.517819  [show with all ESTs]
    Unigene Representative Sequence: NM_001080423
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000273083(uc021wtn.1) ENST00000430219 ENST00000422481(uc003byu.1)
    ENST00000413414(uc003byv.1) ENST00000507975 ENST00000443613(uc010heh.3)
    ENST00000383795

    miRNA
    Products:
         
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GRIP2
    8/77 QIAGEN miScript miRNA Assays for microRNAs that regulate GRIP2 (see all 77):
    hsa-miR-124* hsa-miR-3607-3p hsa-miR-300 hsa-miR-3916 hsa-miR-3150b-3p hsa-miR-92b hsa-miR-877 hsa-miR-4324
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRIP2 (see all 3)
    OriGene shRNA RFP: GRIP2
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRIP2
    Sirion Biotech Custom design and validation of potent shRNA sequences against GRIP2 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: GRIP2 (NM_001080423)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRIP2
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIP2 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRIP2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GRIP2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRIP2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRIP2

    Additional cDNA sequence: 

    AB051506.2 AF052177.1 AK024507.1 AK074145.1 AK095762.1 

    4 DOTS entries:

    DT.402689  DT.100020327  DT.97838340  DT.408313 

    24/36 AceView cDNA sequences (see all 36):

    BX282373 BF116132 AI280245 CK824501 AK024507 BQ721944 AF052177 CA392745 
    AI094434 D20332 AK074145 AK095762 AB051506 BQ022906 AW293960 BI759551 
    BQ574975 BF886628 CB854258 BQ356481 AW749505 BU685368 CK824502 CB250538 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for GRIP2 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12
    SP1:                                            -                 -                                                   
    SP2:              -                             -                                                                     
    SP3:              -                                                                                                   
    SP4:                                                                                                                  
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for GRIP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GRIP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --
    GRIP2 Expression
    About this image

    GRIP2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See GRIP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GRIP2

    SOURCE GeneReport for Unigene cluster: Hs.517819
        SABiosciences Custom PCR Arrays for GRIP2
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRIP2
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GRIP2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRIP2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRIP2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GRIP2 gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Grip21 , 5 glutamate receptor interacting protein 21, 5 83.85(n)1
    88.47(a)1
      6 (40.80 cM)5
    2435471  NM_001159507.11  NP_001152979.11 
     917615095 
    chicken
    (Gallus gallus)
    Aves GRIP21 glutamate receptor interacting protein 2 72.66(n)
    76.24(a)
      416043  XM_414383.3  XP_414383.3 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi03h072 Transcribed sequence with weak similarity to protein refNP_114458.1 (R.norvegicus) Glutamate receptor interacting protein [Rattus norvegicus] less 72.53(n)    57062589 


    ENSEMBL Gene Tree for GRIP2 (if available)
    TreeFam Gene Tree for GRIP2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/939 NCBI SNPs in GRIP2 are shown (see all 939    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs67948011,2
    C,F,A,H--14531382(+) CCACCG/ATCAGG 1 -- ut31 ese321Minor allele frequency- A:0.42NS EA NA WA CSA 2347
    rs1853874181,2
    --14531436(+) CAACAC/GGTCCA 1 -- ut310--------
    rs1902523131,2
    --14531445(+) CATGTA/TTGGGG 1 -- ut310--------
    rs1441946411,2
    --14531499(+) AACTCA/GGGAGT 1 -- ut310--------
    rs1821826151,2
    --14531524(+) GCCCAA/GCTAAC 1 -- ut310--------
    rs46842221,2
    C,H--14531617(+) AGCCTC/ATGCCT 1 -- ut3112Minor allele frequency- A:0.01NA WA CSA 139
    rs1157762071,2
    F--14531622(+) ATGCCT/CACCTG 1 -- ut311Minor allele frequency- C:0.02WA 118
    rs46842231,2
    C,H--14531627(+) TACCTC/GCCTGC 1 -- ut31 ese38Minor allele frequency- G:0.00NA WA EA 134
    rs46842241,2
    C,H--14531631(+) TGCCTC/GCCTCT 1 -- ut319Minor allele frequency- G:0.00NA WA EA 254
    rs107160951,2
    C,F--14531650(+) GTACT-/GGGCCA 1 -- ut315Minor allele frequency- G:0.40NA CSA 10

    HapMap Linkage Disequilibrium report for GRIP2 (14530619 - 14583588 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for GRIP2
         1 CNV: 30174
         1 Indel: 50951

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRIP2
    DNA2.0 Custom Variant and Variant Library Synthesis for GRIP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GRIP2 for disorders           About GeneDecksing

    3 diseases for GRIP2:    About MalaCards
    pituitary adenoma    adenoma    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: GRIP2 (1 document)

    Export disorders for GRIP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GRIP2 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with GRIP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    2. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy- 5-methylisoxazole-4-propionic acid receptor clustering. (PubMed id 11641419)1, 2 Lin S.H.S.... Civelli O. (2001)
    3. Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 2 Hattori A.... Ohara O. (2000)
    4. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10574462)1, 2 Nagase T.... Ohara O. (1999)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    6. A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
    7. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    8. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    9. PICK1 interacts with ABP/GRIP to regulate AMPA receptor trafficking. (PubMed id 16055064)1 Lu W. and Ziff E.B. (2005)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80852 HGNC: 23841 AceView: GRIP2 Ensembl:ENSG00000144596 euGenes: HUgn80852
    ECgene: GRIP2 H-InvDB: GRIP2

    (According to HUGE)
    About This Section
    HUGE: KIAA1719

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GRIP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GRIP2 gene:
    Search GeneIP for patents involving GRIP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for GRIP2  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRIP2   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRIP2  
     OriGene Protein Over-expression Lysate for GRIP2   Browse OriGene Fluorogenic Cell Assay Kits  
     Browse OriGene siRNAs   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIP2  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for GRIP2   OriGene Custom Protein Services for GRIP2  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GRIP2
     Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRIP2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRIP2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRIP2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRIP2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRIP2
     GenScript Custom Purified and Recombinant Proteins Services for GRIP2 GenScript cDNA clones with any tag delivered in your preferred vector for GRIP2
     GenScript Custom Assay Services for GRIP2 GenScript Custom Superior Antibodies Services for GRIP2
     GenScript Custom overexpressing Cell Line Services for GRIP2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in GRIP2 promoter
     Search Chromatin IP Primers for GRIP2
     RT2 qPCR Primer Assay in human, mouse, rat GRIP2
     Search GNC Networks for GRIP2
     SABiosciences Custom PCR Arrays for GRIP2
     Search Tocris compounds for GRIP2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Antibodies for GRIP2
     See all of Abcam's Antibodies, Kits and Proteins for GRIP2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     GRIP2 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for GRIP2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIP2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for GRIP2
     Browse SwitchGear Promoter luciferase reporter plasmids for GRIP2
     Search ThermoFisher Antibodies for GRIP2
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIP2
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GRIP2
    Sirion Biotech Customized:
     stable knockdown cell line services for GRIP2
     inducible knockdown cell line services for GRIP2
     design and validation of potent shRNA sequences against GRIP2
     adenovirus for potent knockdown of GRIP2
     adenovirus for overexpression of GRIP2
     stable overexpressing cell line services for GRIP2
     inducible overexpressing cell line services for GRIP2
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      GRIP2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4