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GRINL1B Gene

pseudogene   GIFtS: 24

GC04P068907
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
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Aliases & Descriptions
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1B1 2
GLURR21 2
Glutamate receptor-like protein 1B3

External Ids:    HGNC: 157121   Entrez Gene: 3399702   Ensembl: ENSG000002277257   UniProtKB: Q9BZD33   

Search outside databases for aliases for GRINL1B gene

Previous GC identifers: GC04U990129 GC04P068842 GC15P055715 GC04P068733 GC04P068586

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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  --
(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC and Ensembl (release 56), Regulatory elements and Epigenetics data according to SABiosciences)
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Regulatory elements:
"" Search SABiosciences Regulatory transcription factor binding sites for GRINL1B ""

Epigenetics:
"" Search SABiosciences Methyl-Profiler DNA Methylation qPCR Primer Assays for GRINL1B ""

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q12   Ensembl cytogenetic band:  4q13.2   HGNC cytogenetic band: 4q12

GRINL1B Gene in genomic location: bands according to Ensembl, locations according to "" (and/or Entrez Gene and/or Ensembl if different)
""

GeneLoc gene densities for chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P068907:  view genomic region     (about GC identifiers)

Start:
68,904,134 bp from pter
End:
68,908,238 bp from pter
Size:
4,105 bases
Orientation:
plus strand
(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene, Novus Biologicals, and/or Sino Biological,
Biochemical Assays by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 May 2010 and Entrez Gene, Antibodies by Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abnova, OriGene, Novus Biologicals, and/or Epitomics)
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UniProtKB/Swiss-Prot: GRL1B_HUMAN, Q9BZD3 (See protein sequence)
Recommended Name: Protein GRINL1B  
Size: 368 amino acids; 41713 Da
Caution: Could be the product of a pseudogene

Post-translational modifications:

  • View phosphorylation sites using PhosphoSite2



  • Human Recombinant Proteins 
    ""Browse Purified and Recombinant Proteins at Millipore
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    ""Browse Origene full length recombinant human proteins expressed in human HEK293 cells
    ""Browse Sino Biological Recombinant Proteins  ""

    1 Gene Ontology (GO) cellular component term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575 cellular_component ND--
    About this table

    "" GRINL1B for ontologies           About GeneDecksing



    Antibodies for GRINL1B: 
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    ""Browse antibodies at Epitomics

    Assays for GRINL1B: 
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    "" Browse R&D Systems for biochemical assays
    ""Browse Enzo Life Sciences for kits & assays

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9BZD3

    UniProtKB/Swiss-Prot: GRL1B_HUMAN, Q9BZD3
    Similarity: Belongs to the GRINL1 family

    (According to MGI May 08 2010, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Millipore, Abnova, siRNAs from Applied Biosystems, Sigma-Aldrich, Clones from Millipore, Sigma-Aldrich, OriGene, Sino Biological, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene.)
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    Inhib.
    RNA:
    ""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): GRINL1B
    Origene shRNA RFP (see all 2): GRINL1B
    Origene basic RS shRNA (see all 2): GRINL1B

    ""Sigma-Aldrich siRNA for GRINL1B
    Browse shRNA at Sigma-Aldrich
    Explore Sigma-Aldrich super-pooled esiRNAs
    Clones:""Browse Clones for the Expression of Recombinant Proteins Available from Millipore
    ""Browse iPSC Reprogramming Factors at Sigma-Aldrich
    "" Origene GFP tagged cDNA clones in CMV expression vector (see all 2): GRINL1B
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): GRINL1B
    Origene untagged cDNA clones in CMV expression vector: GRINL1B
    ""Browse Sino Biological Human cDNA Clones  ""

    1 Gene Ontology (GO) molecular function term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674 molecular_function ND--
    About this table

    "" GRINL1B for ontologies           About GeneDecksing

    (Pathways according to Millipore, Cell Signaling Technology, Sigma-Aldrich, Applied Biosystems GeneAssist, KEGG and/or UniProtKB, (map by GeneGo),
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 May 2010 via Entrez Gene).
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    "" Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GRINL1B

    1 Gene Ontology (GO) biological process term (GO ID links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150 biological_process ND--
    About this table

    "" GRINL1B for ontologies           About GeneDecksing


    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
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    "" GRINL1B for compounds           About GeneDecksing

    "" Enzo Life Sciences drugs & compounds for GRINL1B
    ""Browse Small Molecules at Sigma-Aldrich

    "" Browse Tocris compounds for GRINL1B

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 223 Homo sapiens; Apr 2 2010) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Millipore and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene, microRNA from SABiosciences,
    Tagged/untagged cDNA clones from OriGene, Primers from OriGene and/or SABiosciences,
    Expression Assays from Applied Biosystems)
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    Inhib.
    RNA:
    ""Browse for Gene Knock-down Tools from Millipore
    ""Browse Abnova for Chimera RNAi Products
    "" Origene 29mer shRNA kits in GFP-retroviral vector (see all 2): GRINL1B
    Origene shRNA RFP (see all 2): GRINL1B
    Origene basic RS shRNA (see all 2): GRINL1B

    ""Sigma-Aldrich siRNA for GRINL1B
    Browse shRNA at Sigma-Aldrich
    Explore Sigma-Aldrich super-pooled esiRNAs

    microRNA:""Search SABiosciences for microRNAs that regulate GRINL1B: ""

    Clones:"" Origene GFP tagged cDNA clones in CMV expression vector (see all 2): GRINL1B
    Origene Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): GRINL1B
    Origene untagged cDNA clones in CMV expression vector: GRINL1B
    Primers:"" Origene genome-wide validated SYBR primer pairs: GRINL1B
    ""SABiosciences RT2 qPCR Primer Assay for GRINL1B: PPH23058A ""

    3 AceView cDNA sequences:

    CD108561 BQ717191 AA206441 

    "" highest scoring ESTs for GRINL1B:

    EC543453 AJ617629 


    GeneLoc Exon Structure

    1 Ensembl transcript including schematic representation:
    ENST00000440470  
    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 223 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems, Primers from OriGene and/or SABiosciences )
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    GRINL1B expression in normal and diseased human tissues

    Data from GNF BioGPS
        About these images

    About these images

    CGAP SAGE TAG: --
    Primers:"" Origene genome-wide validated SYBR primer pairs: GRINL1B ""
    ""SABiosciences RT2 qPCR Primer Assay for GRINL1B: PPH23058A ""
    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI May 08 2010, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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    ENSEMBL Gene Tree for GRINL1B
    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
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      --
    (SNPs according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Genotyping Reagents from Applied Biosystems)
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      --
    (in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, LSDB, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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    "" GRINL1B for disorders           About GeneDecksing

    OMIM: 608311

    (Possibly Related Articles in Doctor's Guide)
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    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
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    4 PubMed articles for GRINL1B gene:
    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)
    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 339970 HGNC: 15712 AceView: LOC339970.4 Ensembl:ENSG00000227725 euGenes: HUgn339970
    ECgene: GRINL1B H-InvDB: GRINL1B
    (According to HUGE)
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      --
    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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      --
    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from XenneX, Inc.)
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    Patent Information for GRINL1B gene: ""
    Search GeneIP for patents involving GRINL1B

    GeneCards and IP: ""
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search


    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Novus Biologicals,
    Epitomics, Sigma-Aldrich, R&D Systems, SABiosciences, Millipore, Abnova,
    Clones available from OriGene, Sigma-Aldrich, Sino Biological, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience)
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    ""
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    Products for GRINL1B:
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    "" "Your Favorite Gene" Pathways"" Browse ELISAs at Sigma-Aldrich
    "" Browse iPSC Reprogramming Factors at Sigma-Aldrichfeedback


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    "" Recombinant & Natural Proteins  

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    """"""""
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    "" Purified proteins from HEK293T cells
    "" Western blot validated antibodies
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    "" Custom immunoassay development
    "" Search Tocris compounds for GRINL1B
    "" Search Regulatory tfbs for GRINL1B
    "" Search Chromatin IP Primers for GRINL1B
    "" Search DNA Methylation qPCR Primer Assays for GRINL1B
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    "" Search GNC Networks for GRINL1B
    "" Search for microRNAs that regulate GRINL1B
    """"""""
    "" Drugs for GRINL1B
    "" Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
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