GRIN2D Gene
protein-coding GIFtS: 64
GCID: GC19P048898
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|
glutamate receptor, ionotropic, N-methyl D-aspartate 2D (Previous symbol: NMDAR2D)
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Aliases for GRIN2D gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D1 2 | | Glutamate [NMDA] Receptor Subunit Epsilon-42 3 | | NMDAR2D1 2 3 5 | | N-Methyl D-Aspartate Receptor Subtype 2D2 3 | | EB111 2 3 | | Estrogen Receptor Binding CpG Island2 | | GluN2D1 2 3 | | Glutamate Receptor Ionotropic, NMDA 2D2 | | NR2D1 2 3 | | N-Methyl-D-Aspartate Receptor Subunit 2D2 |
Export aliases for GRIN2D gene to outside databasesPrevious GC identifers: GC19P049542 GC19P049266 GC19P053574 GC19P053589 GC19P045278 |
Summaries for GRIN2D gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GRIN2D: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to beinvolved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thoughtto underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptorsubunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C),and NMDAR2D (GRIN2D). (provided by RefSeq, Mar 2010) UniProtKB/Swiss-Prot: NMDE4_HUMAN, O15399Function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependentsensitivity to magnesium. Mediated by glycine
summary
for GRIN2D: NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes. Gene Wiki entry for GRIN2D
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Genomic Views for GRIN2D gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GRIN2D gene promoter: Pax-5 p53 GATA-1 C/EBPalpha PPAR-gamma1 FOXO1a STAT3 SEF-1 (1) PPAR-gamma2 FOXO1 Other transcription factors
Search SABiosciences Chromatin IP Primers for GRIN2D
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRIN2D |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.33 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.33GRIN2D Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P048898: view genomic region
(about GC identifiers)
Start:
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48,898,132 bp from pter |
End:
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48,948,188 bp from pter |
Size:
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50,057 bases |
Orientation:
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plus strand |
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Proteins for GRIN2D gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: NMDE4_HUMAN, O15399 (See
protein sequence)Recommended Name: Glutamate receptor ionotropic, NMDA 2D precursor Size: 1336 amino acids; 143752 Da
Subunit: Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit(GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B)
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane;Multi-pass membrane proteinExplore the universe of human proteins at neXtProt for GRIN2D: NX_O15399
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15399 GRIN2D Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000827.2 ENSEMBL proteins: ENSP00000263269 Reactome Protein details: O15399 Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
GRIN2D for ontologies About GeneDecksing
GRIN2D Antibody Products: Assay Products for GRIN2D: |
Protein
Domains / Families for GRIN2D gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GRIN2D for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15399ProtoNet protein and cluster: O15399 3 Blocks protein families: IPB001320 Ionotropic glutamate receptor IPB001508 NMDA receptor signature IPB001828 Extracellular ligand-binding receptor
UniProtKB/Swiss-Prot: NMDE4_HUMAN, O15399Similarity: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily |
Function for GRIN2D gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: NMDE4_HUMAN, O15399Function: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependentsensitivity to magnesium. Mediated by glycine Genatlas biochemistry entry for GRIN2D:N-methyl D-aspartate receptor 2,delta subunit glutamate receptor,predominantly expressed,in diencephalicstructures,mesenphalic dopaminergic neurons and in basal ganglia,involved in excitatory neurotransmission and inneuronal cell death,playing a central role in verbal memory and cognitive function
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GRIN2D (NM_000836) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GRIN2D | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIN2D  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIN2D |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004970 | ionotropic glutamate receptor activity |
-- | -- | | GO:0004972 | N-methyl-D-aspartate selective glutamate receptor activity |
IEA | -- | | GO:0005234 | extracellular-glutamate-gated ion channel activity |
IEA | -- | | GO:0005261 | cation channel activity |
-- | -- | | GO:0016595 | glutamate binding |
-- | -- |
GRIN2D for ontologies About GeneDecksing
Animal Models: Mouse knock-out Grin2dtm1Mim for GRIN2D 8 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Grin2d):
GRIN2D for phenotypes About GeneDecksing
|
Pathways & Interactions for GRIN2D gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/21 super-pathways (see all 21) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | CREB phosphorylation through the activation of CaMKII | | | 2 | Post NMDA receptor activation events | | | 3 | Transmission across Chemical Synapses | | | 4 | Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling | | | 5 | Signal transduction Erk Interactions: Inhibition of Erk | |
Pathway sources See GeneCards unified pathways Show all pathways
5 EMD Millipore Pathways for GRIN2D 5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GRIN2D (see all 7) 3 GeneGo (Thomson Reuters) Pathways for GRIN2D 2 BioSystems Pathways for GRIN2D 
5/9
Reactome Pathways for GRIN2D (see all 9)
5/6
Kegg Pathways (Kegg details for GRIN2D) (see all 6):
GRIN2D for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GRIN2D
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/74 Interacting proteins for GRIN2D (O153992, 3 ENSP000002632694) via UniProtKB, MINT, STRING, and/or I2D (see all 74)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table
GRIN2D for ontologies About GeneDecksing
|
Drugs & Compounds for GRIN2D gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GRIN2D for compounds About GeneDecksing
Compounds for GRIN2D available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| (+)-MK 801 maleate | Non-competitive NMDA antagonist, acts at ion channel site | [77086-22-7] | | D-AP5 | Potent, selective NMDA antagonist. More active form of DL-AP5 (Cat. No. 0105) | [79055-68-8] | | PPDA | Subtype-selective NR2C/NR2D antagonist | -- | | SDZ 220-581 | Competitive NMDA antagonist | [174575-17-8] | | L-701,324 | NMDA antagonist, acts glycine site | [142326-59-8] |
3 HMDB Compounds for GRIN2D About this table
4 DrugBank Compounds for GRIN2D About this table
3 Novoseek chemical compound relationships for GRIN2D gene About this table
Search CenterWatch for drugs/clinical trials and news about GRIN2D / NMDE4 
|
Transcripts for GRIN2D gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GRIN2D gene: NM_000836.2 Unigene Cluster for GRIN2D: Glutamate receptor, ionotropic, N-methyl D-aspartate 2D Hs.445015 [show with all ESTs]Unigene Representative Sequence: NM_0008361 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000263269(uc002pjc.4 uc010elx.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GRIN2D (NM_000836) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GRIN2D | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIN2D  |
Additional cDNA sequence: AB209292.1 U77783.1 2 DOTS entries: DT.203006 DT.40122117 13 AceView cDNA sequences: BM551231 NM_000836 BF940611 BF512067 U77783 BF732431 BF507689 AW629560 AI565972 BF196280 BE903642 BM560376 BF941833 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for GRIN2D About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GRIN2D
|
Expression for GRIN2D gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GRIN2D expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTTTTATGCC
About this image See GRIN2D Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GRIN2D
SOURCE GeneReport for Unigene cluster: Hs.445015 SABiosciences Expression via Pathway-Focused PCR Arrays including GRIN2D:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRIN2D Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GRIN2D | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRIN2D | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRIN2D | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIN2D |
Orthologs for GRIN2D gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for GRIN2D gene from 4/12 species (see all 12) About this table
ENSEMBL Gene Tree for GRIN2D (if available) TreeFam Gene Tree for GRIN2D (if available)  |
Paralogs for GRIN2D gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GRIN2D gene
- GRIA32 GRIK12 GRIA22 GRIK22 GRIN12 GRIA12 GRIK32 GRIK42
- GRIN3A2 GRIN2B2 GRIN2A2 GRIK52 GRIN3B2 GRIN2C2 GRIA42 GRID12
- GRID22
5 SIMAP similar genes for GRIN2D using alignment to 1 protein entry: NMDE4_HUMAN:GRIN2B GRIN2A NR2A GRIN2C NMDAR2C
GRIN2D for paralogs About GeneDecksing
|
Genomic Variants for GRIN2D gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 19 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GRIN2D (48898132 - 48948188 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for GRIN2D 5 CNVs: 47965 5106 73397 73398 32261  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRIN2D |
|
Disorders
/ Diseases for GRIN2D gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GRIN2D for disorders About GeneDecksing
OMIM gene information: 602717
OMIM disorders: --
16 diseases for GRIN2D: About MalaCardspaine syndrome amyotrophic lateral sclerosis (als) amyotrophic lateral sclerosis lateral sclerosis fibromyalgia neuronitis bipolar disorder lung carcinoma retinoblastoma neuroblastoma schizophrenia immunodeficiency thyroiditis carcinoma huntington's disease hiv type 1 1 disease from the University of Copenhagen DISEASES database for GRIN2D:Schizophrenia 1 Novoseek disease relationship for GRIN2D gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| fibromyalgia |
40.4 |
1 |
16583480 (1) |
Genetic Association Database (GAD): GRIN2D Human Genome Epidemiology (HuGE) Navigator: GRIN2D (5 documents) Export disorders for GRIN2D gene to outside databases
|
Publications for GRIN2D gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GRIN2D gene, integrated from 9 sources (see all 93): (articles sorted by number of sources associating them with GRIN2D) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of single-nucleotide polymorphisms in the human N-methyl-D-aspartate receptor subunit NR2D gene, GRIN2D, and association study with schizophrenia. (PubMed id 16094258)1, 4, 9 Makino C....Fukumaki Y. (2005)
- Localization of the human NMDAR2D receptor subunit gene (GRIN2D) to 19q13.1-qter, the NMDAR2A subunit gene to 16p13.2 (GRIN2A), and the NMDAR2C subunit gene (GRIN2C) to 17q24-q25 using somatic cell hybrid and radiation hybrid mapping panels. (PubMed id 9480759)1, 3, 9 Kalsi G....Gurling H. (1998)
- Determination of the genomic structure and mutation screening in schizophrenic individuals for five subunits of the N-methyl-D-aspartate glutamate receptor. (PubMed id 12082569)1, 4 Williams N.M....O'Donovan M.C. (2002)
- Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors. (PubMed id 9489750)1, 2 Hess S.D....Velicelebi G. (1998)
- Isolation of estrogen-responsive genes with a CpG island library. (PubMed id 9418891)1, 3 Watanabe T.... Muramatsu M. (1998)
- Cellular distribution of NMDA glutamate receptor subunit mRNAs in the human cerebellum. (PubMed id 9258910)1, 9 Scherzer C.R....Young A.B. (1997)
- Neurotoxicity of human immunodeficiency virus-1: viral proteins and axonal transport. (PubMed id 21948112)1 Mocchetti I....Avdoshina V. (2012)
- HIV immune complexes prevent excitotoxicity by interac tion with NMDA receptors. (PubMed id 22940423)1 Rumbaugh J.A....Nath A. (2012)
- D1/NMDA receptors and concurrent methamphetamine+HIV-1 Tat neurotoxicity. (PubMed id 22552781)1 Aksenov M.Y....Booze R.M. (2012)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for GRIN2D gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GRIN2D gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GRIN2D gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GRIN2D gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for GRIN2D | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GRIN2D gene: Search GeneIP for patents involving GRIN2D
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for GRIN2D gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for GRIN2D | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRIN2D | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRIN2D | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for GRIN2D | | OriGene 3'-UTR Clone for GRIN2D | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRIN2D | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for GRIN2D | | OriGene Custom Protein Services for GRIN2D | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GRIN2D | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRIN2D | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRIN2D | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRIN2D | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRIN2D | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRIN2D |
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 | | GRIN2D Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRIN2D |
|  |  |  | | | Search ThermoFisher Antibodies for GRIN2D |
| | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GRIN2D |
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