GRAP2 Gene
protein-coding GIFtS: 64
GCID: GC22P040297
|
|
GRB2-related adaptor protein 2
| |
Aliases
for GRAP2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| GRB2-Related Adaptor Protein 21 2 | | GRB-2-Like Protein2 3 | | GADS1 2 3 | | SH3-SH2-SH3 Adapter Mona2 3 | | GRBLG1 2 3 | | GRAP-22 | | GRID2 3 5 | | GRPL2 | | GrbX1 2 | | GRB2-Related Adapter Protein 22 | | Grf401 2 | | GRB2-Related Protein With Insert Domain2 | | Mona1 2 | | Grf-403 | | Adapter Protein GRID2 3 | | Growth Factor Receptor-Bound Protein 2-Related Adaptor Protein 22 | | Grf40 Adapter Protein2 3 | | Hematopoietic Cell-Associated Adaptor Protein GRPL2 | | Growth Factor Receptor-Binding Protein2 3 | | SH3-SH2-SH3 Adaptor Molecule2 | | Hematopoietic Cell-Associated Adapter Protein GrpL2 3 | | GRBX3 | | GRB2L2 3 | | Grf-403 | | P382 3 | | Protein GADS3 |
Export aliases for GRAP2 gene to outside databasesPrevious GC identifers: GC22P036911 GC22P038540 GC22P038621 GC22P023272 |
Summaries
for GRAP2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for GRAP2:
This gene encodes a member of the GRB2/Sem5/Drk family. This member is an adaptor-like protein involved inleukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein(GRAP), this protein contains an SH2 domain flanked by two SH3 domains. This protein interacts with other proteins,such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains.Transcript variants utilizing alternative polyA sites exist. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: GRAP2_HUMAN, O75791Function: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc
Gene Wiki entry for GRAP2
|
Genomic Views
for GRAP2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GRAP2 gene promoter:
TBP AML1a Brachyury CUTL1 STAT5A IRF-2 SRY NF-AT4 NF-AT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for GRAP2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRAP2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.2 Ensembl cytogenetic band: 22q13.1 HGNC cytogenetic band: 22q13.2GRAP2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P040297: view genomic region
(about GC identifiers)
Start:
|
40,297,086 bp from pter |
End:
|
40,369,725 bp from pter |
Size:
|
72,640 bases |
Orientation:
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plus strand |
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Proteins
for GRAP2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GRAP2_HUMAN, O75791 (See
protein sequence)Recommended Name: GRB2-related adapter protein 2 Size: 330 amino acids; 37909 Da
Subunit: Interacts with phosphorylated LIME1 upon TCR activation (By similarity). Interacts with phosphorylated LAT andLAX1 upon TCR activation. Interacts with SHB. Interacts with PTPN23
Subcellular location: Nucleus. Cytoplasm. Endosome
Secondary accessions: O43726 Q9NRB7Explore the universe of human proteins at neXtProt for GRAP2: NX_O75791
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75791
GRAP2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004801.1
ENSEMBL proteins: ENSP00000339186 ENSP00000396355 ENSP00000385607 ENSP00000444734 ENSP00000446350 ENSP00000382040 ENSP00000442195 Reactome Protein details: O75791
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
GRAP2 for ontologies About GeneDecksing
GRAP2 Antibody Products:
Assay Products for GRAP2: |
Protein
Domains /
Families
for GRAP2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GRAP2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O75791ProtoNet protein and cluster: O75791 2 Blocks protein families: IPB000980 SH2 domain signature IPB001452 SH3 domain signature
UniProtKB/Swiss-Prot: GRAP2_HUMAN, O75791Similarity: Belongs to the GRB2/sem-5/DRK familySimilarity: Contains 1 SH2 domainSimilarity: Contains 2 SH3 domains |
Function
for GRAP2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: GRAP2_HUMAN, O75791Function: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc Genatlas biochemistry entry for GRAP2:Grb2-related adaptor protein 2,expressed in thymus and spleen interacting with cKIT,EPOR,coupling tyrosine kinase tothe RAS pathway
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GRAP2 (NM_004810) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GRAP2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAP2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAP2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
GRAP2 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for GRAP2:
Animal Models:
Mouse knock-outs for GRAP2: Grap2tm1Amch Grap2tm1Eac
3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Grap2):
GRAP2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for GRAP2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/17 super-pathways (see all 17) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Immune System | | | 2 | PKC-Theta Pathway | | | 3 | CD28 co-stimulation | | | 4 | Immune response CD28 signaling | | | 5 | ICos-ICosL Pathway in T-Helper Cell | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for GRAP2
5/9 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GRAP2 (see all 9)
1  GeneGo (Thomson Reuters) Pathway for GRAP2
5  BioSystems Pathways for GRAP2
5/11 
Reactome Pathways for GRAP2 (see all 11)
1 
Kegg Pathway (Kegg details for GRAP2):
GRAP2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GRAP2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/88 Interacting proteins for GRAP2 (O757911, 2, 3 ENSP000003391864) via UniProtKB, MINT, STRING, and/or I2D (see all 88)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| LCP2 | Q130942, 3, ENSP000000467944 | MINT-4302429 MINT-7306546 MINT-4302374 MINT-4302356 MINT-4302410 MINT-4302332 MINT-7041321 MINT-4302284 MINT-4302391 I2D:
score=10 STRING: ENSP00000046794 | | ERBB2 | P046262, 3, ENSP000002695714 | MINT-74540 I2D:
score=2 STRING: ENSP00000269571 | | ASAP1 | Q9ULH12, 3, ENSP000003502974 | MINT-7145768 I2D:
score=1 STRING: ENSP00000350297 | | PTPN23 | Q9H3S71, 2, 3, ENSP000002655624 | EBI-740418,EBI-724478 MINT-7220138 MINT-7220391 MINT-7220432 I2D:
score=1 STRING: ENSP00000265562 | | CD28 | P107472, 3, ENSP000003248904 | MINT-8036810 MINT-8036795 I2D:
score=4 STRING: ENSP00000324890 |
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
GRAP2 for ontologies About GeneDecksing
|
Drugs & Compounds
for GRAP2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GRAP2 for compounds About GeneDecksing
 Browse Tocris compounds for GRAP2
4 Novoseek chemical compound relationships for GRAP2 gene About this table
Search CenterWatch for drugs/clinical trials and news about GRAP2
|
Transcripts
for GRAP2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GRAP2 gene: NM_004810.2 Unigene Cluster for GRAP2: GRB2-related adaptor protein 2 Hs.517499 [show with all ESTs]Unigene Representative Sequence: BC02600211 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000344138(uc003ayh.2 uc011aom.2 uc011aon.2 uc003ayj.2)
ENST00000420971 ENST00000478445 ENST00000461082 ENST00000407075 ENST00000481263
ENST00000460449 ENST00000540310 ENST00000543252 ENST00000399090 ENST00000544756(uc010gya.2 uc011aoo.2 uc011aop.2 uc011aoq.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: GRAP2 (NM_004810) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GRAP2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAP2 |
Additional cDNA sequence: AF042380.1 AF090456.1 AF102694.1 AF121002.1 AF129476.1 AF236119.1 AF236120.1 AJ011736.1 AK303280.1 AK303332.1 AK303470.1 AK303512.1 AK303657.1 AK312830.1 AY069959.1 BC025692.1 BC026002.1 CR456498.1 CR536524.1 CR541849.1 Y18051.1 8 DOTS entries: DT.433702 DT.95171199 DT.120671271 DT.407834 DT.87015062 DT.100670611 DT.120671280 DT.97777471 24/75 AceView cDNA sequences (see all 75): CR456498 AF090456 CR536524 AF236120 CR607150 H55177 CR598431 AA669142 AF042380 N57907 BC025692 CR604186 NM_004810 AI248165 AF236119 BU584580 AA693791 BX100847 BE646273 BC026002 AW024274 BX437694 BI912538 Y18051
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for GRAP2 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for GRAP2
|
Expression
for GRAP2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GRAP2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTATATATA
About this image
See GRAP2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GRAP2
SOURCE GeneReport for Unigene cluster: Hs.517499
SABiosciences Custom PCR Arrays for GRAP2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRAP2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GRAP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRAP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRAP2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAP2 |
Orthologs
for GRAP2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for GRAP2 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
GRAP21 |
GRB2-related adaptor protein 2 |
69.17(n)
68.26(a) |
|
770756 XM_001234081.2 XP_001234082.2 |
lizard
(Anolis carolinensis) |
Reptilia |
GRAP26 |
-- |
58(a) |
1 ↔ 1 |
5(25514459-25537675) |
zebrafish
(Danio rerio) |
Actinopterygii |
BC058307.12 |
-- |
82.54(n) |
|
393651 BC058307.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
drk6 |
downstream of receptor kinase |
47(a) |
possible ortholog |
2R(9382727-9390342) |
worm
(Caenorhabditis elegans) |
Secernentea |
sem-56 |
Sex muscle abnormal protein 5 |
43(a) |
possible ortholog |
X(7959779-7961677) |
ENSEMBL Gene Tree for GRAP2 (if available)
TreeFam Gene Tree for GRAP2 (if available) |
Paralogs
for GRAP2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for GRAP2 gene
- GRAP2 GRAPL2 NCK12 NCK22 GRB22
18/39 SIMAP similar genes for GRAP2 using alignment to 8 protein entries: GRAP2_HUMAN (see all proteins)
(see all similar genes):ITSN2 ITSN1 GRAP PSTPIP1 GRAPL AHI1
EPS8 VAV1 HCK KIAA0142 PPP1R13B SH3D19
ARHGEF7 SH3GL2 BLK CRK SH3GL1 ABL1
GRAP2 for paralogs About GeneDecksing
|
Genomic Variants
for GRAP2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for GRAP2 (40297086 - 40369725 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GRAP2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRAP2 |
|
Disorders
/ Diseases
for GRAP2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GRAP2 for disorders About GeneDecksing
OMIM gene information: 604518
OMIM disorders: --
16  diseases for GRAP2: About MalaCardssilver-russell syndrome potter's syndrome retinal telangiectasia fanconi's anemia
hepatitis c hepatitis b anemia thyroid carcinoma
hepatocellular carcinoma pancreatic carcinoma hepatitis thyroiditis
carcinoma pancreatitis leukemia neuronitis
1 disease from the University of Copenhagen DISEASES database for GRAP2:Potter's syndrome 2 Novoseek disease relationships for GRAP2 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| necrosis |
0 |
2 |
9831174 (1) |
| tumors |
0 |
4 |
19027225 (1), 9831174 (1) |
Genetic Association Database (GAD): GRAP2
Human Genome Epidemiology (HuGE) Navigator: GRAP2 (4 documents)
Export disorders for GRAP2 gene to outside databases
|
Publications
for GRAP2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GRAP2 gene, integrated from 9 sources (see all 86):
(articles sorted by number of sources associating them with GRAP2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and expression of human grap-2, a novel leukocyte- specific SH2- and SH3-containing adaptor-like protein that binds to gab-1. (PubMed id 9878555)1, 2, 3, 9 Qiu M....Liu M. (1998)
- Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT. (PubMed id 10224278)1, 2, 3 Asada H.... Sugamura K. (1999)
- Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. (PubMed id 10811803)1, 2, 9 Zhang W.... Samelson L.E. (2000)
- Histidine domain-protein tyrosine phosphatase interac ts with Grb2 and GrpL. (PubMed id 21179510)1, 2 Tanase C.A. (2010)
- Genetic variations in humans associated with differences in the course of hepatitis C. (PubMed id 15063762)1, 4 Saito T....Kawata S. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. (PubMed id 12522270)1, 2 Salomon A.R.... Peters E.C. (2003)
- Genomic organization and restricted expression of the human Mona/Gads gene suggests regulation by two specific promoters. (PubMed id 12062812)1, 2 Guyot B.... Mouchiroud G. (2002)
|
External Searches for GRAP2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GRAP2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GRAP2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GRAP2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for GRAP2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GRAP2 gene:
Search GeneIP for patents involving GRAP2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for GRAP2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for GRAP2 | | OriGene shRNA RFP for GRAP2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRAP2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRAP2 | | | OriGene Protein Over-expression Lysate for GRAP2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for GRAP2 | | OriGene 3'-UTR Clone for GRAP2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRAP2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for GRAP2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for GRAP2 | | OriGene Custom Protein Services for GRAP2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GRAP2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRAP2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRAP2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRAP2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRAP2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRAP2 |
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| | | | Search Tocris compounds for GRAP2 |
| |  |  |  |  | | | | | | Recombinant Protein for GRAP2 |
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 | | | GRAP2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAP2 |
|  |  |  | | | | ThermoFisher Antibodies for GRAP2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAP2 |
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