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GRAMD1A Gene

protein-coding   GIFtS: 46
GCID: GC19P035952

GRAM Domain Containing 1A

(Previous name: KIAA1533)
(Previous symbol: KIAA1533)
  Search for GRAMD1A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
GRAM Domain Containing 1A1 2
KIAA15331 2 3
GRAM Domain-Containing Protein 1A2

External Ids:    HGNC: 293051   Entrez Gene: 576552   Ensembl: ENSG000000893517   UniProtKB: Q96CP63   

Export aliases for GRAMD1A gene to outside databases

Previous GC identifers: GC19P040174 GC19P035486 GC19P031999 GC19P035533 GC19P035679 GC19P035789


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GRAMD1A Gene:
GRAMD1A (GRAM domain containing 1A) is a protein-coding gene. An important paralog of this gene is GRAMD1C.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GRAMD1A gene promoter:
         ATF-2   CRE-BP1   HEN1   CREB   Ik-2   FOXO4   deltaCREB   Hand1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): GRAMD1A promoter sequence
   Search Chromatin IP Primers for GRAMD1A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GRAMD1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.13   Ensembl cytogenetic band:  19q13.11   HGNC cytogenetic band: 19q13.13

GRAMD1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GRAMD1A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P035952:  view genomic region     (about GC identifiers)

Start:
35,485,688 bp from pter      End:
35,517,375 bp from pter
Size:
31,688 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: GRM1A_HUMAN, Q96CP6 (See protein sequence)
Recommended Name: GRAM domain-containing protein 1A  
Size: 724 amino acids; 80680 Da
Secondary accessions: A6NKY7 Q8NC77 Q9P1Z5
Alternative splicing: 3 isoforms:  Q96CP6-1   Q96CP6-2   Q96CP6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GRAMD1A: NX_Q96CP6

Explore proteomics data for GRAMD1A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys87, Lys513, Lys655
  • Modification sites at PhosphoSitePlus

  • See GRAMD1A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001129671.1  NP_065946.2  

    ENSEMBL proteins: 
     ENSP00000470220   ENSP00000441032   ENSP00000471290   ENSP00000439267   ENSP00000474401  
     ENSP00000423728  

    GRAMD1A Human Recombinant Protein Products:

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    Novus Biologicals GRAMD1A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GRAMD1A

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    Abcam antibodies for GRAMD1A
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    LSBio Antibodies in human, mouse, rat for GRAMD1A

    GRAMD1A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for GRAMD1A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for GRAMD1A
    Cloud-Clone Corp. CLIAs for GRAMD1A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR004182 GRAM

    Graphical View of Domain Structure for InterPro Entry Q96CP6

    ProtoNet protein and cluster: Q96CP6

    UniProtKB/Swiss-Prot: GRM1A_HUMAN, Q96CP6
    Similarity: Contains 1 GRAM domain


    GRAMD1A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GRAMD1A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GRAMD1A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GRAMD1A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GRAMD1A

    miRNA
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    miRTarBase miRNAs that target GRAMD1A:
    hsa-mir-93-5p (MIRT028025), hsa-mir-7-5p (MIRT025741), hsa-mir-130b-3p (MIRT020153)

    Block miRNA regulation of human, mouse, rat GRAMD1A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GRAMD1A (see all 21):
    hsa-miR-323-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-374a hsa-miR-4260 hsa-miR-519a hsa-miR-4267 hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidGRAMD1A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for GRAMD1A
    Predesigned siRNA for gene silencing in human, mouse, rat GRAMD1A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GRAMD1A

    Clone
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    OriGene clones in human, mouse for GRAMD1A (see all 13)
    OriGene ORF clones in mouse, rat for GRAMD1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): GRAMD1A (NM_001136199)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRAMD1A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAMD1A

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for GRAMD1A 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAMD1A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GRM1A_HUMAN, Q96CP6: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    plasma membrane2
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    GRAMD1A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GRAMD1A
    Interactions:

        Search GeneGlobe Interaction Network for GRAMD1A

    1 Interacting protein for GRAMD1A (Q96CP63) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS6KB1P234433I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GRAMD1A (GRM1A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for GRAMD1A gene (2 alternative transcripts): 
    NM_001136199.1  NM_020895.3  

    Unigene Cluster for GRAMD1A:

    GRAM domain containing 1A
    Hs.515351  [show with all ESTs]
    Unigene Representative Sequence: AK097215
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000599564 ENST00000594597 ENST00000317991(uc002nxi.1 uc010xse.1 uc010xsf.1)
    ENST00000600231 ENST00000603669 ENST00000411896(uc002nxk.2) ENST00000424536
    ENST00000598073 ENST00000599476 ENST00000598580 ENST00000595596 ENST00000598362
    ENST00000598118 ENST00000603907 ENST00000504615(uc002nxl.2 uc002nxn.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GRAMD1A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GRAMD1A (see all 21):
    hsa-miR-323-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-374a hsa-miR-4260 hsa-miR-519a hsa-miR-4267 hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidGRAMD1A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for GRAMD1A
    Predesigned siRNA for gene silencing in human, mouse, rat GRAMD1A
    Clone
    Products:
         
    OriGene clones in human, mouse for GRAMD1A (see all 13)
    OriGene ORF clones in mouse, rat for GRAMD1A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): GRAMD1A (NM_001136199)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRAMD1A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAMD1A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for GRAMD1A
    OriGene qSTAR qPCR primer pairs in human, mouse for GRAMD1A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GRAMD1A
      QuantiTect SYBR Green Assays in human, mouse, rat GRAMD1A
      QuantiFast Probe-based Assays in human, mouse, rat GRAMD1A

    Additional mRNA sequence: 

    AB040966.1 AK026064.1 AK074827.1 AK074864.1 AK074914.1 AK093555.1 AK097215.1 BC014077.2 
    BC041618.1 

    23 DOTS entries:

    DT.214951  DT.100822719  DT.100030331  DT.100030330  DT.100822723  DT.100822722  DT.95159036  DT.100822716 
    DT.92434709  DT.100822718  DT.100822724  DT.91788216  DT.95123137  DT.100000120  DT.121495209  DT.121495228 
    DT.70105069  DT.75178604  DT.75178964  DT.75119439  DT.86849125  DT.91659503  DT.97773700 

    Selected AceView cDNA sequences (see all 307):

    BQ052919 BM553858 BI913537 CD365502 AB040966 BM811118 BU174983 BF438346 
    BM914918 CD367752 BE910346 BE792840 BU624453 BM679722 BU684147 AI741846 
    CR617236 BX432972 BF433795 BQ881928 BI759290 AK026064 AI167872 BF195151 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GRAMD1A (see all 10)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^
    SP1:                          -     -     -           -                       -                 -                                   -                           
    SP2:                                                                          -                 -     -                             -                           
    SP3:                                                                                                                                                            
    SP4:                                      -                                                                                                                     
    SP5:                                                                                                                                                            

    ExUns: 19 ^ 20 ^ 21a · 21b ^ 22a · 22b ^ 23
    SP1:                                -         
    SP2:                                -         
    SP3:                                -         
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for GRAMD1A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GRAMD1A expression in normal human tissues (normalized intensities)      GRAMD1A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GACAGATGGA
    GRAMD1A Expression
    About this image


    GRAMD1A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Lung (Respiratory System)
     
     Spleen (Hematopoietic System)
    GRAMD1A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GRAMD1A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.515351
        Custom PCR Arrays for GRAMD1A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for GRAMD1A
    OriGene qSTAR qPCR primer pairs in human, mouse for GRAMD1A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GRAMD1A
    QuantiTect SYBR Green Assays in human, mouse, rat GRAMD1A
    QuantiFast Probe-based Assays in human, mouse, rat GRAMD1A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAMD1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for GRAMD1A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gramd1a1 , 5 GRAM domain containing 1A1, 5 87.56(n)1
    94.01(a)1
      7 (19.30 cM)5
    528571  NM_027898.31  NP_082174.31 
     311301275 
    lizard
    (Anolis carolinensis)
    Reptilia GRAMD1A6
    GRAM domain containing 1A
    65(a)
    1 ↔ 1
    GL343514.1(80647-142933)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gramd1a1 GRAM domain containing 1A 62.11(n)
    57.27(a)
      100492510  XM_002940531.2  XP_002940577.2 
    zebrafish
    (Danio rerio)
    Actinopterygii gramd1a1 GRAM domain containing 1A 59.48(n)
    54.99(a)
      555994  XM_678684.6  XP_683776.6 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG302846
    CG343946
    --
    20(a)
    18(a)
    many ↔ many
    many ↔ many
    2R(17538325-17539504)
    2L(3358640-3373372)
    worm
    (Caenorhabditis elegans)
    Secernentea ZC328.36
    Protein ZC328.3, isoform b (ZC328.3) mRNA, complet...
    23(a)
    1 → many
    I(6409060-6416883) WBGene00022593
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes --
    YSP26
    Protein of unknown function that may interact with...
    Protein involved in programmed cell death; mutant ...
    10(a)
    10(a)
    many ↔ many
    many ↔ many
    VIII(262801-266838) YHR080C
    IV(1120609-1124925) YDR326C


    ENSEMBL Gene Tree for GRAMD1A (if available)
    TreeFam Gene Tree for GRAMD1A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GRAMD1A gene
    GRAMD1C2  GRAMD22  GRAMD32  GRAMD1B2  
    3 SIMAP similar genes for GRAMD1A using alignment to 5 protein entries:     GRM1A_HUMAN (see all proteins):
    GRAMD1B    GRAMD1C    GRAMD3

    GRAMD1A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GRAMD1A (see all 776)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1449901191,2
    --35489270(+) TGGTGC/TGATCC 2 -- us2k10--------
    rs1486767161,2
    C--35489448(+) GTGATC/TCACCC 2 -- us2k10--------
    rs781012091,2
    C,F--35489705(+) GGCACG/AGCGAT 2 -- us2k11Minor allele frequency- A:0.08WA 118
    rs1995800991,2
    C--35489711(+) GCGAT-/AGGGGG 2 -- us2k10--------
    rs1825308961,2
    --35489713(+) GATAGC/GGGGGG 2 -- us2k10--------
    rs621221471,2
    C--35489748(+) CAGTGC/TAAAGG 2 -- us2k13Minor allele frequency- T:0.10NA EA 242
    rs1422156681,2
    C--35489785(+) CTGGTA/GAGTTA 2 -- us2k10--------
    rs1141720421,2
    C,F--35489806(+) GGGTAG/TGCTGG 2 -- us2k11Minor allele frequency- T:0.02WA 118
    rs1871395331,2
    --35489867(+) CAGGGG/TCCTTG 2 -- us2k10--------
    rs1512251611,2
    C--35490001(+) GACAGC/TAGGGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for GRAMD1A (35485688 - 35517375 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for GRAMD1A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv911613CNV Loss21882294
    dgv3848n71CNV Loss21882294
    nsv911610CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GRAMD1A
    DNA2.0 Custom Variant and Variant Library Synthesis for GRAMD1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GRAMD1A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with GRAMD1A)
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    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2000)
    2. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)1, 2 Otsuki T....Isogai T. (DNA Res. 2005)
    3. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    4. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57655 HGNC: 29305 AceView: KIAA1533 Ensembl:ENSG00000089351 euGenes: HUgn57655
    ECgene: GRAMD1A H-InvDB: GRAMD1A

    (According to HUGE)
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    HUGE: KIAA1533

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GRAMD1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GRAMD1A gene:
    Search GeneIP for patents involving GRAMD1A

    GeneCards and IP:
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