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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GRAMD1A Gene

protein-coding GIFtS: 43
GCID: GC19P035679

GRAM domain containing 1A

(Previous name: KIAA1533 )
(Previous symbol: KIAA1533)

Search for GRAMD1A
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
GRAM Domain Containing 1A¹ ²
KIAA1533¹ ² ³
FLJ90346¹
GRAM Domain-Containing Protein 1A²

External Ids:	HGNC: 29305¹	Entrez Gene: 57655²	Ensembl: ENSG00000089351⁷	UniProtKB: Q96CP6³

Export aliases for GRAMD1A gene to outside databases

Previous GC identifers: GC19P040174 GC19P035486 GC19P031999 GC19P035533

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GRAMD1A gene promoter:
ATF-2 CRE-BP1 HEN1 CREB Ik-2 FOXO4 deltaCREB Hand1 Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): GRAMD1A promoter sequence

Search SABiosciences Chromatin IP Primers for GRAMD1A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GRAMD1A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.13 Ensembl cytogenetic band: 19q13.11 HGNC cytogenetic band: 19q13.13

GRAMD1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GRAMD1A gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P035679: view genomic region (about GC identifiers)

Start:	35,491,227 bp from pter	End:	35,517,373 bp from pter
Size:	26,147 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GRM1A_HUMAN, Q96CP6 (See protein sequence)

Recommended Name: GRAM domain-containing protein 1A

Size: 724 amino acids; 80680 Da

Subcellular location: Membrane; Single-pass membrane protein (Potential)

Secondary accessions: A6NKY7 Q8NC77 Q9P1Z5

Alternative splicing: 3 isoforms: Q96CP6-1 Q96CP6-2 Q96CP6-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GRAMD1A: NX_Q96CP6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96CP6

GRAMD1A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001129671.1 NP_065946.2

ENSEMBL proteins:

ENSP00000441032 ENSP00000439267 ENSP00000423728

Human Recombinant Protein Products for GRAMD1A:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals GRAMD1A Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for GRAMD1A

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016021	integral to membrane	IEA	--

GRAMD1A for ontologies About GeneDecksing

GRAMD1A Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	Browse OriGene Antibodies OriGene Custom Antibody Services for GRAMD1A
	GenScript Custom Superior Antibodies Services for GRAMD1A
	Novus Biologicals GRAMD1A Antibodies
	Abcam antibodies for GRAMD1A
	Uscn Antibodies for GRAMD1A
	Search ThermoFisher Antibodies for GRAMD1A

Assay Products for GRAMD1A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for GRAMD1A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for GRAMD1A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GRAMD1A for domains About GeneDecksing

1 InterPro domain/family:

IPR004182 GRAM

Graphical View of Domain Structure for InterPro Entry Q96CP6

ProtoNet protein and cluster: Q96CP6

UniProtKB/Swiss-Prot: GRM1A_HUMAN, Q96CP6

Similarity: Contains 1 GRAM domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GRAMD1A

miRNA Products:		OriGene 3'-UTR Clone (see all 2): GRAMD1A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GRAMD1A
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate GRAMD1A (see all 21):
		hsa-miR-323-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-374a hsa-miR-4260 hsa-miR-519a hsa-miR-4267 hsa-miR-374c

		SwitchGear 3'UTR luciferase reporter plasmid: GRAMD1A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRAMD1A (see all 7) OriGene shRNA RFP: GRAMD1A Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRAMD1A
		Sirion Biotech Custom design and validation of potent shRNA sequences against GRAMD1A

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for GRAMD1A
			Sirion Biotech Customized adenovirus for overexpression of GRAMD1A Sirion Biotech Customized adenovirus for potent knockdown of GRAMD1A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRAMD1A (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRAMD1A (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): GRAMD1A (NM_001136199)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRAMD1A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAMD1A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for GRAMD1A
		Search LifeMap BioReagents cell lines for GRAMD1A
		Sirion Biotech Customized stable knockdown cell line services for GRAMD1A Sirion Biotech Customized inducible knockdown cell line services for GRAMD1A Sirion Biotech Customized stable overexpressing cell line services for GRAMD1A Sirion Biotech Customized inducible overexpressing cell line services for GRAMD1A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAMD1A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for GRAMD1A

1 Interacting protein for GRAMD1A (Q96CP6³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
RPS6KB1	P23443³	I2D: score=1

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GRAMD1A
Search CenterWatch for drugs/clinical trials and news about GRAMD1A / GRM1A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GRAMD1A gene (2 alternative transcripts):

NM_001136199.1 NM_020895.3

Unigene Cluster for GRAMD1A:

GRAM domain containing 1A

Hs.515351 [show with all ESTs]

Unigene Representative Sequence: AK097215

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000317991(uc002nxi.1 uc010xse.1 uc010xsf.1) ENST00000411896(uc002nxk.2)

ENST00000504615(uc002nxl.2 uc002nxn.1)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): GRAMD1A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GRAMD1A
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate GRAMD1A (see all 21):
		hsa-miR-323-3p hsa-miR-3194-5p hsa-miR-106a hsa-miR-374a hsa-miR-4260 hsa-miR-519a hsa-miR-4267 hsa-miR-374c

		SwitchGear 3'UTR luciferase reporter plasmid: GRAMD1A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRAMD1A (see all 7) OriGene shRNA RFP: GRAMD1A Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GRAMD1A
		Sirion Biotech Custom design and validation of potent shRNA sequences against GRAMD1A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GRAMD1A (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GRAMD1A (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): GRAMD1A (NM_001136199)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GRAMD1A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAMD1A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRAMD1A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GRAMD1A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRAMD1A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRAMD1A

Additional cDNA sequence:

AB040966.1 AK026064.1 AK074827.1 AK074864.1 AK074914.1 AK093555.1 AK097215.1 BC014077.2

BC041618.1

23 DOTS entries:

DT.214951 DT.100822719 DT.100030331 DT.100030330 DT.100822723 DT.100822722 DT.95159036 DT.100822716

DT.92434709 DT.100822718 DT.100822724 DT.91788216 DT.95123137 DT.100000120 DT.121495209 DT.121495228

DT.70105069 DT.75178604 DT.75178964 DT.75119439 DT.86849125 DT.91659503 DT.97773700

24/307 AceView cDNA sequences (see all 307):

BM553858 BU731181 BE792840 BQ917714 CD368895 BU737871 BX115368 BP334342

BF195221 BU174983 BM787373 BE910346 CR601407 BM561402 BX432972 BM746370

BQ644826 BF433795 BE888512 BQ649454 CD367242 BM679722 BQ892925 BI913537

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for GRAMD1A (see all 10) About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7	^	8a	·	8b	^	9	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	^	13a	·	13b	^	14a	·	14b	^	15a	·	15b	^	16	^	17	^	18	^
SP1:									-		-		-				-								-						-												-
SP2:																									-						-		-										-
SP3:
SP4:													-
SP5:

ExUns:	19	^	20	^	21a	·	21b	^	22a	·	22b	^	23
SP1:											-
SP2:											-
SP3:											-
SP4:
SP5:

ECgene alternative splicing isoforms for GRAMD1A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GRAMD1A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACAGATGGA

About this image

GRAMD1A expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Liver

Liver Lobule

Liver

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See GRAMD1A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GRAMD1A

SOURCE GeneReport for Unigene cluster: Hs.515351

SABiosciences Custom PCR Arrays for GRAMD1A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRAMD1A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GRAMD1A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GRAMD1A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GRAMD1A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAMD1A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for GRAMD1A gene from 6/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	GRAMD1A⁶	--	65(a)	1 ↔ 1	GL343514.1(82341-142933)
zebrafish (Danio rerio)	Actinopterygii	gramd1a¹	GRAM domain containing 1A	59.16(n) 54.97(a)		555994 XM_678684.5 XP_683776.5
fruit fly (Drosophila melanogaster)	Insecta	CG30284⁶ CG34394⁶	--	19(a) 16(a)	many ↔ many many ↔ many	2R(17538325-17539504) 2L(3358640-3373372)
worm (Caenorhabditis elegans)	Secernentea	ZC328.3⁶	Protein ZC328.3, isoform b	21(a)	possible ortholog	I(6409062-6416885)
thale cress (Arabidopsis thaliana)	eudicotyledons	VAD1¹	GRAM domain family protein	41.22(n) 33(a)		839232 NM_100092.2 NP_171714.2
rice (Oryza sativa)	Liliopsida	Os07g0491600¹	hypothetical protein	--		4343272 NM_001066214.1 NP_001059679.1

ENSEMBL Gene Tree for GRAMD1A (if available)
TreeFam Gene Tree for GRAMD1A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GRAMD1A gene

GRAMD1C² GRAMD2² GRAMD3² GRAMD1B²

2 SIMAP similar genes for GRAMD1A using alignment to 6 protein entries: GRM1A_HUMAN (see all proteins):

GRAMD1B GRAMD1C

GRAMD1A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs144990119^1,2		--	35489270(+)	`TGGTGC/TGATCC`	2	--	us2k¹		0	--	--	--	--
rs148676716^1,2		--	35489448(+)	`GTGATC/TCACCC`	2	--	us2k¹		0	--	--	--	--
rs78101209^1,2	F	--	35489705(+)	`GGCACG/AGCGAT`	2	--	us2k¹		1		WA	118
rs199580099^1,2		--	35489711(+)	`GCGAT-/AGGGGG`	2	--	us2k¹		0	--	--	--	--
rs182530896^1,2		--	35489713(+)	`GATAGC/GGGGGG`	2	--	us2k¹		0	--	--	--	--
rs62122147^1,2	C	--	35489748(+)	`CAGTGC/TAAAGG`	2	--	us2k¹		3		NA EA	242
rs142215668^1,2		--	35489785(+)	`CTGGTA/GAGTTA`	2	--	us2k¹		0	--	--	--	--
rs114172042^1,2	F	--	35489806(+)	`GGGTAG/TGCTGG`	2	--	us2k¹		1		WA	118
rs187139533^1,2		--	35489867(+)	`CAGGGG/TCCTTG`	2	--	us2k¹		0	--	--	--	--
rs151225161^1,2		--	35490001(+)	`GACAGC/TAGGGG`	2	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for GRAMD1A (35491227 - 35517373 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GRAMD1A: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GRAMD1A

DNA2.0 Custom Variant and Variant Library Synthesis for GRAMD1A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GRAMD1A gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with GRAMD1A)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)^{1, 2, 3} Nagase T.... Ohara O. (2000)
Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PubMed id 16303743)^{1, 2} Otsuki T....Isogai T. (2005)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 57655	HGNC: 29305	AceView: KIAA1533	Ensembl:ENSG00000089351	euGenes: HUgn57655
ECgene: GRAMD1A	H-InvDB: GRAMD1A

(According to HUGE)
About This Section

HUGE: KIAA1533

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GRAMD1A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for GRAMD1A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for GRAMD1A gene:
Search GeneIP for patents involving GRAMD1A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Browse OriGene Antibodies		OriGene shRNA RFP for GRAMD1A
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GRAMD1A		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GRAMD1A
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GRAMD1A
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	GenScript Custom Purified and Recombinant Proteins Services for GRAMD1A		GenScript cDNA clones with any tag delivered in your preferred vector for GRAMD1A
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	Regulatory tfbs in GRAMD1A promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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GRAMD1A Proteins, Antibodies, CLIAs, and ELISAs

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	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GRAMD1A

	SwitchGear 3'UTR luciferase reporter plasmids for GRAMD1A
	SwitchGear Promoter luciferase reporter plasmids for GRAMD1A

Search ThermoFisher Antibodies for GRAMD1A

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GRAMD1A

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GRAMD1A

Sirion Biotech Customized:

	stable knockdown cell line services for GRAMD1A
	inducible knockdown cell line services for GRAMD1A
	design and validation of potent shRNA sequences against GRAMD1A
	adenovirus for potent knockdown of GRAMD1A
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	stable overexpressing cell line services for GRAMD1A
	inducible overexpressing cell line services for GRAMD1A

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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GRAMD1A Gene

GRAM domain containing 1A

Aliasesfor GRAMD1A gene

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Genomic Viewsfor GRAMD1A gene

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for GRAMD1A gene

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for GRAMD1A gene

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for GRAMD1A gene

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for GRAMD1A gene

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for GRAMD1A gene

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for GRAMD1A gene

Expression
for GRAMD1A gene

Orthologs
for GRAMD1A gene

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for GRAMD1A gene

Intellectual Property
for GRAMD1A gene

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for GRAMD1A gene