Aliases for GPX6 Gene
External Ids for GPX6 Gene
Previous HGNC Symbols for GPX6 Gene
Previous GeneCards Identifiers for GPX6 Gene
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPX6 Gene
GPX6 (Glutathione Peroxidase 6) is a Protein Coding gene. Diseases associated with GPX6 include keshan disease. Among its related pathways are Insulin secretion and Selenium Metabolism and Selenoproteins. GO annotations related to this gene include glutathione peroxidase activity. An important paralog of this gene is GPX4.