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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GPX6 Gene

protein-coding   GIFtS: 54
GCID: GC06M028471

Glutathione Peroxidase 6 (Olfactory)

(Previous name: glutathione peroxidase pseudogene 3)
(Previous symbol: GPXP3)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Glutathione Peroxidase 6 (Olfactory)1 2     GPX5p2
GPXP31 2     dJ1186N242
Glutathione Peroxidase Pseudogene 31 2     dJ1186N24.12
GPx-62 3     Glutathione Peroxidase 62
GSHPx-62 3     EC 1.11.18
EC 1.11.1.93 8     

External Ids:    HGNC: 45581   Entrez Gene: 2572022   Ensembl: ENSG000001987047   OMIM: 6079135   UniProtKB: P597963   

Export aliases for GPX6 gene to outside databases

Previous GC identifers: GC00U990129 GC06M028541 GC06P028601 GC06M028579 GC06M028277


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GPX6 Gene:
This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen
peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA
codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop
structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon
rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium.
(provided by RefSeq, Jul 2008)

GeneCards Summary for GPX6 Gene: 
GPX6 (glutathione peroxidase 6 (olfactory)) is a protein-coding gene. Diseases associated with GPX6 include favism, and keshan disease, and among its related super-pathways are Glutathione metabolism and Arachidonic acid metabolism. GO annotations related to this gene include glutathione peroxidase activity. An important paralog of this gene is GPX5.

Gene Wiki entry for GPX6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007592.15  NT_113891.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GPX6 gene promoter:
         Elk-1   AML1a   SRF (504 AA)   MIF-1   C/EBPalpha   SRY   PPAR-gamma1   FOXO1a   PPAR-gamma2   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGPX6 promoter sequence
   Search SABiosciences Chromatin IP Primers for GPX6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPX6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p22.1

GPX6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPX6 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M028471:  view genomic region     (about GC identifiers)

Start:
28,471,073 bp from pter      End:
28,495,992 bp from pter
Size:
24,920 bases      Orientation:
minus strand

1 alternative location:
Chr6-,NT_113891.2 732-5,774     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GPX6_HUMAN, P59796 (See protein sequence)
Recommended Name: Glutathione peroxidase 6 precursor  
Size: 221 amino acids; 24971 Da
Subcellular location: Secreted (By similarity)
Secondary accessions: Q4PJ17

Explore the universe of human proteins at neXtProt for GPX6: NX_P59796

Explore proteomics data for GPX6 at MOPED 

4/10 DME Specific Peptides for GPX6 (P59796) (see all 10)
 KGDVNGE  WNFEKFL  ELNALQE  FPCNQFG 

GPX6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

GPX6 Protein Expression
REFSEQ proteins: NP_874360.1  
ENSEMBL proteins: 
 ENSP00000354581   ENSP00000417364  

Human Recombinant Protein Products for GPX6: 
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Cloud-Clone Corp. Proteins for GPX6 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--

GPX6 for ontologies           About GeneDecksing



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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
2 InterPro protein domains:
 IPR012336 Thioredoxin-like_fold
 IPR000889 Glutathione_peroxidase

Graphical View of Domain Structure for InterPro Entry P59796

ProtoNet protein and cluster: P59796

1 Blocks protein domain: IPB000889 Glutathione peroxidase

UniProtKB/Swiss-Prot: GPX6_HUMAN, P59796
Similarity: Belongs to the glutathione peroxidase family


GPX6 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: GPX6_HUMAN, P59796
Catalytic activity: 2 glutathione + H(2)O(2) = glutathione disulfide + 2 H(2)O

     Enzyme Numbers (IUBMB): EC 1.11.1.91 2 EC 1.11.12

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004602glutathione peroxidase activity IEA--
     
GPX6 for ontologies           About GeneDecksing


Animal Models:
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miRNA
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hsa-miR-3607-5p hsa-miR-1294 hsa-miR-631 hsa-miR-767-3p hsa-miR-571 hsa-miR-3661 hsa-miR-1270 hsa-miR-3150b-3p
SwitchGear 3'UTR luciferase reporter plasmidGPX6 3' UTR sequence
Inhib. RNA
Products:
    
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In Situ Assay
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for GPX6 About   (see all 7)                                                                                              See pathways by source

SuperPathContained pathways About
1Glutathione metabolism
Glutathione metabolism0.92
Glutathione metabolism0.67
2Arachidonic acid metabolism
Arachidonic acid metabolism0.44
3Insulin secretion
Thyroid hormone synthesis0.36
4glutathione redox reactions I
glutathione redox reactions I
5Selenium Pathway
Selenium Pathway

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 EMD Millipore Pathway for GPX6
    Glutathione metabolism


1 GeneGo (Thomson Reuters) Pathway for GPX6
    Glutathione metabolism

4 BioSystems Pathways for GPX6
    Selenium Metabolism and Selenoproteins
Selenium Pathway
Folate Metabolism
glutathione redox reactions I


3         Kegg Pathways  (Kegg details for GPX6):
    Glutathione metabolism
Arachidonic acid metabolism
Thyroid hormone synthesis


GPX6 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPX6

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/35 Interacting proteins for GPX6 (ENSP000003545814) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
InteractantInteraction Details
GeneCardExternal ID(s)
GGT1ENSP000002489234STRING: ENSP00000248923
GGT5ENSP000003813404STRING: ENSP00000381340
GGT6ENSP000003709624STRING: ENSP00000370962
GGT7ENSP000003389644STRING: ENSP00000338964
GSSENSP000002169514STRING: ENSP00000216951
About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006979response to oxidative stress IEA--
GO:0055114oxidation-reduction process ----

GPX6 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GPX6

10 HMDB Compounds for GPX6    About this table
CompoundSynonyms CAS #PubMed Ids
15(S)-HETE15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid (see all 17)54845-95-3--
15(S)-HPETE(5Z,8Z,11Z,13E)-(15S)-15-Hydroperoxyicosa-5,8,11,13-tetraenoate (see all 8)70981-96-3--
5(S)-Hydroperoxyeicosatetraenoic acid5-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid (see all 6)71774-08-8--
5-HETE5(S)-HETE (see all 14)70608-72-9--
5-HPETE5(S)-HPETE (see all 7)74581-83-2--
Glutathione5-L-Glutamyl-L-cysteinylglycine (see all 32)70-18-8--
Hydrogen peroxideHydrogen peroxide (see all 44)7722-84-1--
Oxidized glutathioneGSSG (see all 4)27025-41-8--
Seleniumselenium (see all 5)7782-49-2--
WaterDihydrogen oxide (see all 2)7732-18-5--

1 DrugBank Compound for GPX6    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
Glutathione5-L-Glutamyl-L-cysteinylglycine (see all 5)70-18-8targetcofactor3532684 17081103 17588737 17139284 17016423

Search CenterWatch for drugs/clinical trials and news about GPX6

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GPX6 gene: 
NM_182701.1  

Unigene Cluster for GPX6:

Glutathione peroxidase 6 (olfactory)
Hs.448570
Unigene Representative Sequence: AY324826
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000361902(uc021yrx.1 uc010jrg.1) ENST00000474923 ENST00000474923
ENST00000483058
Congresses - knowledge worth sharing:  
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

miRNA
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hsa-miR-3607-5p hsa-miR-1294 hsa-miR-631 hsa-miR-767-3p hsa-miR-571 hsa-miR-3661 hsa-miR-1270 hsa-miR-3150b-3p
SwitchGear 3'UTR luciferase reporter plasmidGPX6 3' UTR sequence
Inhib. RNA
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Clone
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  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GPX6

Additional mRNA sequence: 

AY324826.1 BC133691.1 BC148315.2 

1 DOTS entry:

DT.101977842 

2 AceView cDNA sequences:

NM_182701 AY324826 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GPX6 expression in normal human tissues (normalized intensities)      GPX6 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GCACCTGGGC
GPX6 Expression
About this image


GPX6 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/23 selected tissues (see all 23) fully expand
 
 Brain (Nervous System)    fully expand to see all 10 entries
         Thalamus
         ganglion/cranial   
 
 Neural Tube (Nervous System)    fully expand to see all 3 entries
         Metencephalon
 
 Lower Urinary Tract (Urinary System)    fully expand to see all 2 entries
         Ureter
         visceral organ   
 
 Lung (Respiratory System)    fully expand to see all 2 entries
         Stem Bronchi
 
 Nose (Sensory Organs)    fully expand to see all 2 entries
         sensory organ/nose/nasal cavity   

See GPX6 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.448570

UniProtKB/Swiss-Prot: GPX6_HUMAN, P59796
Tissue specificity: Expressed in olfactory epithelium and embryos

    SABiosciences Expression via Pathway-Focused PCR Arrays including GPX6: 
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          Nitric Oxide Signaling Pathway in human mouse rat
          Molecular Toxicology PathwayFinder 384HT in human mouse rat

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPX6

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals and fungi.

Orthologs for GPX6 gene from 5/12 species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Gpx61 , 5 glutathione peroxidase 61, 5 81.06(n)1
72.27(a)1
  13 (7.74 cM)5
755121  NM_145451.31  NP_663426.21 
 213122175 
chicken
(Gallus gallus)
Aves GPX36
Glutathione peroxidase
58(a)
1 → many
13(12377503-12379482)
zebrafish
(Danio rerio)
Actinopterygii gpx36
CU469585.16
Glutathione peroxidase
55(a)
34(a)
1 ↔ many
possible ortholog
14(51699364-51719884)
12(46629768-46638624)
worm
(Caenorhabditis elegans)
Secernentea gpx-56
gpx-36
(see all 3)
Glutathione peroxidase
(see all 3)
32(a)
31(a)
(see all 3)
possible ortholog
possible ortholog
(see all 3)
X(9584664-9586490)
X(9587942-9588879)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes HYR16
GPX26
(see all 3)
Thiol peroxidase that functions as a hydroperoxide...
Phospholipid hydroperoxide glutathione peroxidase ...
(see all 3)
36(a)
35(a)
(see all 3)
many ↔ many
many ↔ many
(see all 3)
IX(423128-423619)
II(707528-708016)


ENSEMBL Gene Tree for GPX6 (if available)
TreeFam Gene Tree for GPX6 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for GPX6 gene
GPX52  GPX22  GPX72  GPX42  GPX12  GPX32  GPX82  
4 SIMAP similar genes for GPX6 using alignment to 3 protein entries:     GPX6_HUMAN (see all proteins):
GPX3    GPX5    GPX2    GPX1

GPX6 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/402 SNPs in GPX6 are shown (see all 402)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1413619851,2
--28470605(+) CCTGTA/GCTCTC 1 -- ds50010--------
rs746243561,2
F--28470905(+) AAAAAA/CAAACA 1 -- ds50013Minor allele frequency- C:0.06CSA WA NA 240
rs1996784851,2
--28470909(+) AAAAA-/CAAACA 1 -- ds50010--------
rs1496507911,2
C--28470930(+) GTTGT-/ACAGAGA 1 -- ds50010--------
rs1480631991,2
--28470949(+) GGATTC/GTTTGA 1 -- ds50010--------
rs789193741,2
C--28471015(+) GCAGAA/GGGACC 1 -- ds50010--------
rs348746031,2
C--28471161(-) CCTGCT/CTTCTT 1 -- ut315Minor allele frequency- C:0.00NS 186
rs356047091,2
C,F--28471297(-) CTGAGC/TCTCCT 1 -- ut319Minor allele frequency- T:0.15NS NA WA EA 550
rs593731451,2
C,F--28471424(+) GTTTTG/AGGATC 1 -- ut311Minor allele frequency- A:0.50WA 2
rs359217651,2
C,F--28471560(-) TGCATT/GGTTAA 1 -- ut3111Minor allele frequency- G:0.22NS NA WA EA 554

HapMap Linkage Disequilibrium report for GPX6 (28471073 - 28495992 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for GPX6:    About this table     
Variant IDTypeSubtypePubMed ID
nsv830621CNV Gain17160897

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing GPX6
DNA2.0 Custom Variant and Variant Library Synthesis for GPX6

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 607913    OMIM disorders: --

4 diseases for GPX6:    About MalaCards
favism    keshan disease    pneumonia    endotheliitis

1 disease from the University of Copenhagen DISEASES database for GPX6:
Keshan disease

GPX6 for disorders           About GeneDecksing

Genetic Association Database (GAD): GPX6
Human Genome Epidemiology (HuGE) Navigator: GPX6 (5 documents)

Export disorders for GPX6 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for GPX6 gene, integrated from 9 sources (see all 15):
(articles sorted by number of sources associating them with GPX6)
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  1. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
  2. Glutathione pathway genetic polymorphisms and lung ca ncer survival after platinum-based chemotherapy. (PubMed id 20200426)1, 4 Moyer A.M....Weinshilboum R.M. (2010)
  3. Characterization of mammalian selenoproteomes. (PubMed id 12775843)1, 2 Kryukov G.V.... Gladyshev V.N. (2003)
  4. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
  5. Apoptosis induced by oxidized lipids is associated with up-regulation of p66Shc in intestinal Caco-2 cells: protective effects of phenolic compounds. (PubMed id 17588737)7 Giovannini C....Masella R. (2008)
  6. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)7 Imming P....Meyer A. (2006)
  7. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
  8. Glutathione peroxidases and redox-regulated transcrip tion factors. (PubMed id 17081103)7 Brigelius-FlohAc R. (2006)
  9. HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells. (PubMed id 15910762)1 Price T.O....Banks W.A. (2005)
  10. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 257202 HGNC: 4558 AceView: GPX6 Ensembl:ENSG00000198704 euGenes: HUgn257202
ECgene: GPX6 Kegg: 257202 H-InvDB: GPX6

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for GPX6 Pharmacogenomics, SNPs, Pathways
NIEHS-SNPshttp://egp.gs.washington.edu/data/gpx6/

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for GPX6 gene:
Search GeneIP for patents involving GPX6

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