Aliases for GPRC5B Gene
Aliases for GPRC5B Gene
External Ids for GPRC5B Gene
- HGNC: 13308
- Entrez Gene: 51704
- Ensembl: ENSG00000167191
- OMIM: 605948
- UniProtKB: Q9NZH0
Previous GeneCards Identifiers for GPRC5B Gene
- GC16M019362
- GC16M019797
- GC16M019836
- GC16M019777
- GC16M018406
Summaries for GPRC5B Gene
-
This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
GeneCards Summary for GPRC5B Gene
GPRC5B (G Protein-Coupled Receptor Class C Group 5 Member B) is a Protein Coding gene. Among its related pathways are GPCRs, Class C Metabotropic glutamate, pheromone. GO annotations related to this gene include G-protein coupled receptor activity and G-protein coupled receptor binding. An important paralog of this gene is GPRC5C.
UniProtKB/Swiss-Prot for GPRC5B Gene
-
Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPRC5B Gene
Genomics for GPRC5B Gene
Regulatory Elements for GPRC5B Gene
Enhancers for GPRC5B Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH16G019881 | 1.5 | FANTOM5 ENCODE dbSUPER | 16.4 | +2.5 | 2496 | 4.0 | RB1 SIN3A RAD21 ETS1 GLIS2 EGR1 ZNF202 ZNF680 ZHX2 CEBPB | GPRC5B C16orf62 KNOP1 CCP110 LARP7P2 |
| GH16G019859 | 1.1 | Ensembl ENCODE dbSUPER | 12.4 | +25.1 | 25129 | 3.7 | FOXA2 JUND POLR2A POU5F1 ZBTB33 EBF1 CHD7 ATF2 | KNOP1 GPRC5B C16orf62 ACSM5 LARP7P2 |
| GH16G019757 | 1.3 | FANTOM5 ENCODE dbSUPER | 10.1 | +127.9 | 127915 | 0.8 | ELF3 SOX13 SAP130 CEBPG DMAP1 RARA TEAD3 ZNF350 CREM GATAD2A | KNOP1 THUMPD1 GPRC5B CCP110 IQCK LOC105371115 |
| GH16G019857 | 0.6 | dbSUPER | 12.4 | +27.8 | 27765 | 1.4 | ZFHX2 FOXA2 EGR1 GLIS1 SP7 EGR2 | KNOP1 GPRC5B C16orf62 LARP7P2 |
| GH16G019606 | 0.4 | ENCODE | 17.7 | +278.4 | 278393 | 2.0 | FOS | GPRC5B IQCK KNOP1 ENSG00000259925 CCP110 C16orf62 GC16M019688 GC16M019687 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around GPRC5B on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for GPRC5B Gene
- Chromosome:
- 16
- Start:
- 19,856,691 bp from pter
- End:
- 19,886,167 bp from pter
- Size:
- 29,477 bases
- Orientation:
- Minus strand
Genomic View for GPRC5B Gene
Genes around GPRC5B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16p12.3 by Ensembl
- 16p12.3 by Entrez Gene
- 16p12.3 by HGNC
GPRC5B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GPRC5B Gene
Proteins for GPRC5B Gene
-
Protein details for GPRC5B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NZH0-GPC5B_HUMAN
- Recommended name:
- G-protein coupled receptor family C group 5 member B
- Protein Accession:
- Q9NZH0
- D2DFB0
- O75205
- Q8NBZ8
Protein attributes for GPRC5B Gene
- Size:
- 403 amino acids
- Molecular mass:
- 44795 Da
- Quaternary structure:
- No Data Available
Protein Expression for GPRC5B Gene
Post-translational modifications for GPRC5B Gene
Other Protein References for GPRC5B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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- antibodies-online Antibodies for GPRC5B: See all 76
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-
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Protein Products
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- antibodies-online Proteins for GPRC5B: See all 5
- Search antibodies-online for peptides
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No data available for DME Specific Peptides for GPRC5B Gene
Domains & Families for GPRC5B Gene
Gene Families for GPRC5B Gene
- HGNC:
- IUPHAR :
Suggested Antigen Peptide Sequences for GPRC5B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9NZH0- Family:
-
- Belongs to the G-protein coupled receptor 3 family.
Function for GPRC5B Gene
Molecular function for GPRC5B Gene
- UniProtKB/Swiss-Prot Function:
- Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
- UniProtKB/Swiss-Prot Induction:
- By all-trans retinoic acid (ATRA).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001664 | G-protein coupled receptor binding | ISS | -- |
| GO:0004871 | signal transducer activity | IEA | -- |
| GO:0004930 | G-protein coupled receptor activity | IEA | -- |
| GO:0019901 | protein kinase binding | ISS | -- |
| GO:0030295 | protein kinase activator activity | IDA | 23169819 |
Phenotypes for GPRC5B Gene
- MGI mutant phenotypes for GPRC5B:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for GPRC5B:
-
- Increased vaccinia virus (VACV) infection
- Increased gamma-H2AX phosphorylation
- Decreased viability
- shRNA abundance <= 50%
- Lamellipodia cells
- Dynamic nuclei (hole, folded or small irregular)
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Increased transferrin (TF) endocytosis
- Synthetic lethal with c-Myc after tamoxifen stimulation
- Increased Nanog expression
Animal Models for GPRC5B Gene
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- Search ViGene Biosciences for GPRC5B
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miRNA for GPRC5B Gene
- miRTarBase miRNAs that target GPRC5B
-
- hsa-mir-3187-3p (MIRT498376)
- hsa-mir-4435 (MIRT498377)
- hsa-mir-588 (MIRT498378)
- hsa-mir-4701-5p (MIRT498379)
- hsa-mir-548s (MIRT498380)
- hsa-mir-3926 (MIRT498381)
- hsa-mir-5189-3p (MIRT498382)
- hsa-mir-212-5p (MIRT498383)
- hsa-mir-512-5p (MIRT498384)
- hsa-mir-4523 (MIRT498385)
- hsa-mir-2113 (MIRT557468)
- hsa-mir-636 (MIRT557469)
- hsa-mir-4712-3p (MIRT557470)
- hsa-mir-218-5p (MIRT557471)
miRNA Products
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-
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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Cell Line Products
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No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GPRC5B Gene
Localization for GPRC5B Gene
Subcellular locations from UniProtKB/Swiss-Prot for GPRC5B Gene
- Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Localized in the plasma membrane and perinuclear vesicles.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 4 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005615 | extracellular space | IDA | 16502470 |
| GO:0005634 | nucleus | IDA | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for GPRC5B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | GPCRs, Class C Metabotropic glutamate, pheromone | ||
Pathways by source for GPRC5B Gene
1 BioSystems pathway for GPRC5B Gene
Interacting Proteins for GPRC5B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001934 | positive regulation of protein phosphorylation | IEA | -- |
| GO:0007165 | signal transduction | IEA | -- |
| GO:0007186 | G-protein coupled receptor signaling pathway | IEA | -- |
| GO:0007626 | locomotory behavior | IEA | -- |
| GO:0010976 | positive regulation of neuron projection development | IEA | -- |
No data available for SIGNOR curated interactions for GPRC5B Gene
Transcripts for GPRC5B Gene
mRNA/cDNA for GPRC5B Gene
- (4) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (346) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for GPRC5B Gene
CRISPR Products
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-
Santa Cruz Biotechnology (SCBT) CRISPR for GPRC5B
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miRNA Products
- Search ViGene Biosciences for GPRC5B
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for GPRC5B
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ViGene Biosciences ready-to-package AAV shRNAs for GPRC5B gene
Clone Products
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- Addgene plasmids for GPRC5B
- VectorBuilder custom plasmid, inducible vectors for GPRC5B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GPRC5B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for GPRC5B
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||
| SP5: |
Expression for GPRC5B Gene
mRNA differential expression in normal tissues according to GTEx for GPRC5B Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x5.3), Brain - Substantia nigra (x4.3), and Brain - Caudate (basal ganglia) (x4.1).
This gene is overexpressed in Urine (59.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GPRC5B Gene
NURSA nuclear receptor signaling pathways regulating expression of GPRC5B Gene:
GPRC5BSOURCE GeneReport for Unigene cluster for GPRC5B Gene:
Hs.148685mRNA Expression by UniProt/SwissProt for GPRC5B Gene:
Q9NZH0-GPC5B_HUMAN
Tissue specificity:
Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.
Evidence on tissue expression from TISSUES for GPRC5B Gene
- Nervous system(5)
- Kidney(2.4)
- Muscle(2.2)
Primer Products
-
OriGene qPCR primer pairs for GPRC5B
-
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No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPRC5B Gene
Orthologs for GPRC5B Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GPRC5B 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | GPRC5B 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | GPRC5B 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Gprc5b 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Gprc5b 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | GPRC5B 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | GPRC5B 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | GPRC5B 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | gprc5b 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.3029 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC570207 34 |
|
||
| gprc5ba 35 |
|
OneToMany | |||
| gprc5bb 35 |
|
OneToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for GPRC5B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for GPRC5B Gene
(3) SIMAP similar genes for GPRC5B Gene using alignment to 7 proteins:
Variants for GPRC5B Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000166718 | -- | 19,865,322(+) | GATGC(A/G)TTTAT | intron-variant | |
| rs1000276436 | -- | 19,869,203(+) | ATGCA(A/C)CTGTA | intron-variant | |
| rs1000344869 | -- | 19,859,536(+) | GCCCT(A/G)CTAGG | utr-variant-3-prime | |
| rs1000361769 | -- | 19,877,256(+) | CCTGC(-/T)TTTTT | intron-variant | |
| rs1000417351 | -- | 19,877,656(+) | ACTTC(A/G)CGTAT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv103121 | CNV | deletion | 16902084 |
| nsv1069928 | CNV | deletion | 25765185 |
| nsv1134507 | CNV | deletion | 24896259 |
| nsv428321 | CNV | loss | 18775914 |
| nsv436835 | CNV | insertion | 17901297 |
Residual Variation Intolerance Score:
44.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.63;
45.36% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for GPRC5B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GPRC5B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPRC5B Gene
Disorders for GPRC5B Gene
Relevant External Links for GPRC5B
No disorders were found for GPRC5B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPRC5B Gene
Publications for GPRC5B Gene
- Sequence and expression pattern of a novel human orphan G-protein- coupled receptor, GPRC5B, a family C receptor with a short amino- terminal domain. (PMID: 10783259) Braeuner-Osborne H. … Krogsgaard-Larsen P. (Genomics 2000) 2 3 4 22 64
- Molecular cloning and characterization of two novel retinoic acid- inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). (PMID: 10945465) Robbins M.J. … Pangalos M.N. (Genomics 2000) 3 4 22 64
- Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. (PMID: 10493829) Loftus B.J. … Adams M.D. (Genomics 1999) 2 3 4 64
- L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. (PMID: 20424473) Yokoyama K. … Hosoya T. (Nephron Clin Pract 2010) 3 46 64
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PMID: 20935630) Speliotes E.K. … Loos R.J. (Nat. Genet. 2010) 3 46 64
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- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for GPRC5B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio