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Aliases for GPRASP2 Gene

Aliases for GPRASP2 Gene

  • G Protein-Coupled Receptor Associated Sorting Protein 2 2 3
  • G-Protein Coupled Receptor-Associated Sorting Protein 2 3
  • GASP-2 4
  • GASP2 3

External Ids for GPRASP2 Gene

Previous GeneCards Identifiers for GPRASP2 Gene

  • GC0XP101773
  • GC0XP101853
  • GC0XP101974
  • GC0XP091571
  • GC0XP101977
  • GC0XP101979
  • GC0XP101985

Summaries for GPRASP2 Gene

Entrez Gene Summary for GPRASP2 Gene

  • The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine receptor and the calcitonin receptor. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

GeneCards Summary for GPRASP2 Gene

GPRASP2 (G Protein-Coupled Receptor Associated Sorting Protein 2) is a Protein Coding gene. Diseases associated with GPRASP2 include autism spectrum disorder. An important paralog of this gene is ARMCX6.

UniProtKB/Swiss-Prot for GPRASP2 Gene

  • May play a role in regulation of a variety of G-protein coupled receptors.

Gene Wiki entry for GPRASP2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPRASP2 Gene

Genomics for GPRASP2 Gene

Regulatory Elements for GPRASP2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for GPRASP2 Gene

102,712,176 bp from pter
102,717,733 bp from pter
5,558 bases
Plus strand

Genomic View for GPRASP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GPRASP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPRASP2 Gene

Proteins for GPRASP2 Gene

  • Protein details for GPRASP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G-protein coupled receptor-associated sorting protein 2
    Protein Accession:
    Secondary Accessions:
    • D3DXA0
    • Q8NAB4

    Protein attributes for GPRASP2 Gene

    838 amino acids
    Molecular mass:
    93773 Da
    Quaternary structure:
    • Interacts with cytoplasmic tails of a variety of G-protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR.

neXtProt entry for GPRASP2 Gene

Proteomics data for GPRASP2 Gene at MOPED

Post-translational modifications for GPRASP2 Gene

  • Ubiquitination at Lys39
  • Modification sites at PhosphoSitePlus

Other Protein References for GPRASP2 Gene

No data available for DME Specific Peptides for GPRASP2 Gene

Domains for GPRASP2 Gene

Gene Families for GPRASP2 Gene

  • ARMC :Armadillo repeat containing

Protein Domains for GPRASP2 Gene

Suggested Antigen Peptide Sequences for GPRASP2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q96D09
  • Belongs to the GPRASP family.
genes like me logo Genes that share domains with GPRASP2: view

Function for GPRASP2 Gene

Molecular function for GPRASP2 Gene

UniProtKB/Swiss-Prot Function: May play a role in regulation of a variety of G-protein coupled receptors.

Gene Ontology (GO) - Molecular Function for GPRASP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001540 beta-amyloid binding IEA --
GO:0005488 binding --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GPRASP2: view

Phenotypes for GPRASP2 Gene

GenomeRNAi human phenotypes for GPRASP2:
genes like me logo Genes that share phenotypes with GPRASP2: view

Animal Model Products

CRISPR Products

miRNA for GPRASP2 Gene

miRTarBase miRNAs that target GPRASP2

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for GPRASP2 Gene

Localization for GPRASP2 Gene

Subcellular locations from

Jensen Localization Image for GPRASP2 Gene COMPARTMENTS Subcellular localization image for GPRASP2 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for GPRASP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with GPRASP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for GPRASP2 Gene

Pathways for GPRASP2 Gene

SuperPathways for GPRASP2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPRASP2 Gene


No data available for Pathways by source for GPRASP2 Gene

Transcripts for GPRASP2 Gene

Unigene Clusters for GPRASP2 Gene

G protein-coupled receptor associated sorting protein 2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPRASP2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPRASP2 Gene

No ASD Table

Relevant External Links for GPRASP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GPRASP2 Gene

mRNA expression in normal human tissues for GPRASP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for GPRASP2 Gene

SOURCE GeneReport for Unigene cluster for GPRASP2 Gene Hs.731996

mRNA Expression by UniProt/SwissProt for GPRASP2 Gene

Tissue specificity: Expressed in the brain.
genes like me logo Genes that share expressions with GPRASP2: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for GPRASP2 Gene

Orthologs for GPRASP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPRASP2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia GPRASP2 36
  • 99 (a)
(Bos Taurus)
Mammalia GPRASP2 36
  • 80 (a)
(Canis familiaris)
Mammalia GPRASP2 36
  • 83 (a)
(Mus musculus)
Mammalia Gprasp2 16
Gprasp2 36
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 28 (a)
(Gallus gallus)
Aves -- 36
  • 22 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 22 (a)
(Danio rerio)
Actinopterygii ARMCX3 36
  • 18 (a)
Species with no ortholog for GPRASP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPRASP2 Gene

Gene Tree for GPRASP2 (if available)
Gene Tree for GPRASP2 (if available)

Paralogs for GPRASP2 Gene

Selected SIMAP similar genes for GPRASP2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GPRASP2: view

Variants for GPRASP2 Gene

Sequence variations from dbSNP and Humsavar for GPRASP2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
VAR_049265 -

Structural Variations from Database of Genomic Variants (DGV) for GPRASP2 Gene

Variant ID Type Subtype PubMed ID
nsv526716 CNV Gain 19592680

Relevant External Links for GPRASP2 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPRASP2 Gene

Disorders for GPRASP2 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for GPRASP2 Gene including...

Search for GPRASP2 Gene in MalaCards »
genes like me logo Genes that share disorders with GPRASP2: view

No data available for UniProtKB/Swiss-Prot for GPRASP2 Gene

Publications for GPRASP2 Gene

  1. Identification of a novel family of G protein-coupled receptor associated sorting proteins. (PMID: 15086532) Simonin F. … Kieffer B.L. (J. Neurochem. 2004) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  5. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3

Products for GPRASP2 Gene

Sources for GPRASP2 Gene

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