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GPR85 Gene

protein-coding   GIFtS: 52
GCID: GC07M112720

G Protein-Coupled Receptor 85

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
G Protein-Coupled Receptor 851 2
SREB22 3 5
Super Conserved Receptor Expressed In Brain 22 3
SREB2
Probable G-Protein Coupled Receptor 852
Seven Transmembrane Helix Receptor2

External Ids:    HGNC: 45361   Entrez Gene: 543292   Ensembl: ENSG000001646047   OMIM: 6051885   UniProtKB: P608933   

Export aliases for GPR85 gene to outside databases

Previous GC identifers: GC07M111205 GC07M112267 GC07M112280 GC07M112314 GC07M112507 GC07M107088


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GPR85 Gene:
Members of the G protein-coupled receptor (GPCR) family, such as GPR85, have a similar structure characterized by
7 transmembrane domains. Activation of GPCRs by extracellular stimuli, such as neurotransmitters, hormones, or
light, induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins
(Matsumoto et al., 2000 (PubMed 10833454)).(supplied by OMIM, Aug 2008)

GeneCards Summary for GPR85 Gene:
GPR85 (G protein-coupled receptor 85) is a protein-coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is GPR173.

UniProtKB/Swiss-Prot: GPR85_HUMAN, P60893
Function: Orphan receptor

Gene Wiki entry for GPR85 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GPR85 gene promoter:
         GR   ATF-2   CUTL1   POU3F2   Evi-1   S8   SRY   POU2F1   POU2F1a   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): GPR85 promoter sequence
   Search Chromatin IP Primers for GPR85

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GPR85


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31   Ensembl cytogenetic band:  7q31.1   HGNC cytogenetic band: 7q31

GPR85 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR85 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M112720:  view genomic region     (about GC identifiers)

Start:
112,718,386 bp from pter      End:
112,727,833 bp from pter
Size:
9,448 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 112,088,951-112,096,319     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GPR85_HUMAN, P60893 (See protein sequence)
Recommended Name: Probable G-protein coupled receptor 85  
Size: 370 amino acids; 41995 Da
Secondary accessions: Q9JHI6 Q9NPD1

Explore the universe of human proteins at neXtProt for GPR85: NX_P60893

Explore proteomics data for GPR85 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn3, Asn83, Asn182

  • See GPR85 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001139737.1  NP_001139738.1  NP_001139739.1  NP_061843.3  

    ENSEMBL proteins: 
     ENSP00000476863   ENSP00000297146   ENSP00000396763   ENSP00000401178   ENSP00000415699  
     ENSP00000416722   ENSP00000445808  

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    Cloud-Clone Corp. Proteins for GPR85

     
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    Search eBioscience for ELISAs for GPR85 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPCRAO: GPCR / Class A : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: GPR85
    Class A Orphans

    2 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry P60893

    ProtoNet protein and cluster: P60893

    UniProtKB/Swiss-Prot: GPR85_HUMAN, P60893
    Similarity: Belongs to the G-protein coupled receptor 1 family


    Find genes that share domains with GPR85           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GPR85_HUMAN, P60893
    Function: Orphan receptor

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity TAS10833454
         
    Find genes that share ontologies with GPR85           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for GPR85:
     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gpr85):
     behavior/neurological  growth/size/body  nervous system 

    Find genes that share phenotypes with GPR85           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Gpr85tm1Mima for GPR85

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GPR85
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GPR85

    miRNA
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    Block miRNA regulation of human, mouse, rat GPR85 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GPR85 (see all 120):
    hsa-miR-140-5p hsa-miR-100* hsa-miR-607 hsa-miR-3146 hsa-miR-199a-3p hsa-miR-4325 hsa-miR-298 hsa-miR-3148
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GPR85_HUMAN, P60893: Cell membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with GPR85           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for GPR85 About    
    See pathways by source

    SuperPathContained pathways About
    1Peptide ligand-binding receptors
    GPCRs, Class A Rhodopsin-like0.43


    1 BioSystems Pathway for GPR85
        GPCRs, Class A Rhodopsin-like



        Pathway & Disease-focused RT2 Profiler PCR Array including GPR85: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for GPR85

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS10833454
    GO:0007186G-protein coupled receptor signaling pathway ----

    Find genes that share ontologies with GPR85           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GPR85



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GPR85 gene (4 alternative transcripts): 
    NM_001146265.1  NM_001146266.1  NM_001146267.1  NM_018970.6  

    Unigene Cluster for GPR85:

    G protein-coupled receptor 85
    Hs.152009  [show with all ESTs]
    Unigene Representative Sequence: NM_001146265
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000610164 ENST00000297146 ENST00000424100 ENST00000449591 ENST00000449735
    ENST00000438062 ENST00000487573 ENST00000501255(uc010ljv.2 uc003vgp.1 uc003vgq.2 uc010ljw.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GPR85 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GPR85 (see all 120):
    hsa-miR-140-5p hsa-miR-100* hsa-miR-607 hsa-miR-3146 hsa-miR-199a-3p hsa-miR-4325 hsa-miR-298 hsa-miR-3148
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GPR85
    Primer
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    OriGene qPCR primer pairs and template standards for GPR85
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GPR85
      QuantiTect SYBR Green Assays in human, mouse, rat GPR85
      QuantiFast Probe-based Assays in human, mouse, rat GPR85

    Additional mRNA sequence: 

    AB040800.1 AF250237.2 AK297464.1 AK302769.1 AK309392.1 AK312587.1 AL161959.1 BC030577.1 

    5 DOTS entries:

    DT.70100926  DT.307158  DT.121106438  DT.121106435  DT.95146749 

    Selected AceView cDNA sequences (see all 34):

    CR609708 AW513647 AL540052 BI915894 AI631153 AB040800 AL161959 BC030577 
    AA732890 BQ771598 CD246165 T06908 AF250237 BX453573 BX431250 BG719824 
    AI673342 NM_018970 AI910962 AW148538 AI219897 AL540051 AI200800 AA883367 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GPR85 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f
    SP1:              -     -                                             
    SP2:              -     -                                             
    SP3:                    -                                             
    SP4:                    -                                             
    SP5:                    -     -                                       


    ECgene alternative splicing isoforms for GPR85

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GPR85 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTTTGAAACT
    GPR85 Expression
    About this image


    GPR85 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Mature Endothelial Cells Blood Brain Barrier
             Cerebral Cortex
     
     Endothelium (Cardiovascular System)
             Mature Endothelial Cells Blood Brain Barrier
    GPR85 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GPR85 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.152009

    UniProtKB/Swiss-Prot: GPR85_HUMAN, P60893
    Tissue specificity: Highly expressed in brain and testis. Lower levels in small intestine, placenta and spleen. In
    brain regions, detected in all regions tested, but somewhat lower levels in the corpus callosum, medulla and
    spinal cord

        Pathway & Disease-focused RT2 Profiler PCR Array including GPR85: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for GPR85 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gpr851 , 5 G protein-coupled receptor 851, 5 94.95(n)1
    100(a)1
      6 (5.76 cM)5
    644501  NM_145066.41  NP_659503.11 
     138344585 
    chicken
    (Gallus gallus)
    Aves GPR851 G protein-coupled receptor 85 91.17(n)
    99.73(a)
      417775  XM_004937542.1  XP_004937599.1 
    lizard
    (Anolis carolinensis)
    Reptilia GPR856
    G protein-coupled receptor 85
    99(a)
    1 ↔ 1
    5(58700217-58701329)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gpr851 G protein-coupled receptor 85 87.39(n)
    98.92(a)
      779743  NM_001078822.1  NP_001072290.1 
    zebrafish
    (Danio rerio)
    Actinopterygii sreb22 sreb2 78.48(n)   57927  BC054645.1 


    ENSEMBL Gene Tree for GPR85 (if available)
    TreeFam Gene Tree for GPR85 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GPR85 gene
    GPR1732  GPR272  
    7 SIMAP similar genes for GPR85 using alignment to 5 protein entries:     GPR85_HUMAN (see all proteins):
    GPR173    GPR27    CXCR2    HCRTR2    HTR4    ADRA1A
    ADRA2C

    Find genes that share paralogs with GPR85           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GPR85 (see all 171)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1421505811,2
    --112719974(+) GTTTTA/GGAAGT 4 -- int10--------
    rs1851062431,2
    --112720000(+) GAAGGC/GAACTT 4 -- int10--------
    rs1463171831,2
    C--112720089(+) TGATTC/TGTGTA 4 -- int10--------
    rs1894801651,2
    --112720109(+) GAAAGG/TTTCCT 4 -- int10--------
    rs764605261,2
    C,F--112720170(+) TAATAT/CATACG 4 -- int11Minor allele frequency- C:0.03EA 120
    rs737155101,2
    C,F--112720175(+) TATACG/AAGATC 4 -- int14Minor allele frequency- A:0.22WA CSA 124
    rs1170518491,2
    F--112720310(+) TTGCTA/GCTATG 4 -- int11Minor allele frequency- G:0.01EA 120
    rs1383396961,2
    --112720325(+) TATTGA/TTTCTT 4 -- int10--------
    rs1818564981,2
    --112720523(+) AATCAG/TTTAAC 4 -- ut310--------
    rs1845159661,2
    --112720595(+) AATAGA/GTTATC 4 -- ut310--------

    HapMap Linkage Disequilibrium report for GPR85 (112718386 - 112727833 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for GPR85:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv435847CNV Deletion17901297
    nsv5907CNV Insertion18451855
    dgv7463n71CNV Loss21882294
    nsv464689CNV Gain19166990
    dgv2130e1CNV Complex17122850
    nsv7405OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GPR85
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605188    OMIM disorders: --


    Find genes that share disorders with GPR85           About GenesLikeMe

    Genetic Association Database (GAD): GPR85

    Export disorders for GPR85 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GPR85 gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with GPR85)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system. (PubMed id 10833454)1, 2, 3, 9 Matsumoto M.... Furuichi K. (Biochem. Biophys. Res. Commun. 2000)
    2. The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31. (PubMed id 10978537)1, 2, 3 Hellebrand S.... Wittenberger T. (Biochim. Biophys. Acta 2000)
    3. Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)1, 4 Anney R.J....Gill M. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    4. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    5. A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain. (PubMed id 15893849)1, 9 Matsumoto M....Kleinman J.E. (Brain Res. Mol. Brain Res. 2005)
    6. Effect of schizophrenia risk-associated alleles in SREB2 (GPR85) on functional MRI phenotypes in healthy volunteers. (PubMed id 22968816)1 Radulescu E....Marenco S. (Neuropsychopharmacology 2013)
    7. The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia. (PubMed id 18413613)1 Matsumoto M....Weinberger D.R. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. (PubMed id 19043545)4 Gieger C....Suhre K. (PLoS Genet. 2008)
    9. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54329 HGNC: 4536 AceView: GPR85 Ensembl:ENSG00000164604 euGenes: HUgn54329
    ECgene: GPR85 H-InvDB: GPR85

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GPR85 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GPR85 gene:
    Search GeneIP for patents involving GPR85

    GeneCards and IP:
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