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GPR65 Gene

protein-coding   GIFtS: 57
GCID: GC14P088471

G Protein-Coupled Receptor 65

  Search for GPR65
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
G Protein-Coupled Receptor 651 2
TDAG82 3 5
G-Protein Coupled Receptor 652 3
T-Cell Death-Associated Gene 8 Protein2 3
hTDAG82
Psychosine Receptor2

External Ids:    HGNC: 45171   Entrez Gene: 84772   Ensembl: ENSG000001400307   OMIM: 6046205   UniProtKB: Q8IYL93   

Export aliases for GPR65 gene to outside databases

Previous GC identifers: GC14P085976 GC14P082288 GC14P086461 GC14P087541 GC14P068641


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GPR65 Gene:
GPR65 (G protein-coupled receptor 65) is a protein-coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is FFAR3.

UniProtKB/Swiss-Prot: PSYR_HUMAN, Q8IYL9
Function: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a
role in activation-induced cell death or differentiation of T-cells

Gene Wiki entry for GPR65 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the GPR65 gene promoter:
         Max1   ER-alpha   C/EBPbeta   NF-1   FOXO3   C/EBPalpha   FOXO3b   FAC1   FOXO3a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGPR65 promoter sequence
   Search Chromatin IP Primers for GPR65

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GPR65


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q31-q32.1   Ensembl cytogenetic band:  14q31.3   HGNC cytogenetic band: 14q31-q32.1

GPR65 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR65 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P088471:  view genomic region     (about GC identifiers)

Start:
88,471,468 bp from pter      End:
88,481,155 bp from pter
Size:
9,688 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PSYR_HUMAN, Q8IYL9 (See protein sequence)
Recommended Name: Psychosine receptor  
Size: 337 amino acids; 39333 Da
Secondary accessions: O75819

Explore the universe of human proteins at neXtProt for GPR65: NX_Q8IYL9

Explore proteomics data for GPR65 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn2, Asn79, Asn166
  • Modification sites at PhosphoSitePlus

  • See GPR65 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003599.2  
    ENSEMBL proteins: 
     ENSP00000267549  
    Reactome Protein details: Q8IYL9

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPCRAO: GPCR / Class A : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: GPR65
    Class A Orphans

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR005464 Psych_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q8IYL9

    ProtoNet protein and cluster: Q8IYL9

    1 Blocks protein domain: IPB005464 Psychosine receptor signature

    UniProtKB/Swiss-Prot: PSYR_HUMAN, Q8IYL9
    Similarity: Belongs to the G-protein coupled receptor 1 family


    Find genes that share domains with GPR65           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PSYR_HUMAN, Q8IYL9
    Function: Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. May have a
    role in activation-induced cell death or differentiation of T-cells

         Genatlas biochemistry entry for GPR65:
    G protein coupled receptor 65,predominantly expressed in lymphoid tissues,G protein coupled receptor superfamily

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IDA15618224
         
    Find genes that share ontologies with GPR65           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Gpr65):
     hematopoietic system  immune system 

    Find genes that share phenotypes with GPR65           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GPR65
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    hsa-miR-569 hsa-miR-588 hsa-miR-376b hsa-miR-26b* hsa-miR-3617 hsa-miR-3647-3p hsa-miR-512-3p hsa-miR-376a
    SwitchGear 3'UTR luciferase reporter plasmidGPR65 3' UTR sequence
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    Predesigned siRNA for gene silencing in human, mouse, rat GPR65

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PSYR_HUMAN, Q8IYL9: Cell membrane; Multi-pass membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS9655242
    GO:0016021integral component of membrane ----

    Find genes that share ontologies with GPR65           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for GPR65 About    
    See pathways by source

    SuperPathContained pathways About
    1Peptide ligand-binding receptors
    Class A/1 (Rhodopsin-like receptors)0.71
    GPCRs, Class A Rhodopsin-like0.43
    GPCR ligand binding0.71
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90
    3Gastrin-CREB signalling pathway via PKC and MAPK
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    G alpha (q) signalling events0.90


    Find genes that share SuperPaths with GPR65           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for GPR65
        GPCRs, Class A Rhodopsin-like

    2 Reactome Pathways for GPR65
        G alpha (q) signalling events
    Class A/1 (Rhodopsin-like receptors)


        Pathway & Disease-focused RT2 Profiler PCR Array including GPR65: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for GPR65

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GPR65 (ENSP000002675494) via UniProtKB, MINT, STRING, and/or I2D (see all 123)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BDKRB1ENSP000002166294STRING: ENSP00000216629
    CYSLTR2ENSP000002820184STRING: ENSP00000282018
    FFAR2ENSP000002465494STRING: ENSP00000246549
    FPR2ENSP000003401914STRING: ENSP00000340191
    GNRH1ENSP000002764144STRING: ENSP00000276414
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0006955immune response TAS9655242
    GO:0007186G-protein coupled receptor signaling pathway IDA15618224
    GO:0007275multicellular organismal development TAS9655242
    GO:0010447response to acidity IDA15618224

    Find genes that share ontologies with GPR65           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GPR65 (PSYR)

    2 Novoseek inferred chemical compound relationships for GPR65 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psychosine 84.4 1 11309421 (1)
    lysophosphatidylcholine 60.4 2 15280385 (1)



    Find genes that share compounds with GPR65           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GPR65 gene: 
    NM_003608.3  

    Unigene Cluster for GPR65:

    G protein-coupled receptor 65
    Hs.443243  [show with all ESTs]
    Unigene Representative Sequence: NM_003608
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000267549(uc001xvv.3)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate GPR65 (see all 15):
    hsa-miR-569 hsa-miR-588 hsa-miR-376b hsa-miR-26b* hsa-miR-3617 hsa-miR-3647-3p hsa-miR-512-3p hsa-miR-376a
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      QuantiFast Probe-based Assays in human, mouse, rat GPR65

    Additional mRNA sequence: 

    AK313797.1 BC035633.1 BC071715.1 EU883574.1 

    3 DOTS entries:

    DT.205257  DT.40228234  DT.95270486 

    Selected AceView cDNA sequences (see all 33):

    CD246175 BI767444 BE326632 CB266201 AI707599 BI823897 AI445416 CD522351 
    AI344626 BI764698 AI017452 BI836708 BI518633 BX093977 BC071715 BI824101 
    BI908385 AI376916 AA298823 BI909137 NM_003608 BI819962 AV716718 BC035633 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GPR65 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAGGGGACT
    GPR65 Expression
    About this image


    GPR65 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Epithelial Cells
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
     
     Eye (Sensory Organs)
             Adult Retinal Pigmented Epithelium Cells Retinal Pigmented Epithelium
    GPR65 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GPR65 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.443243

    UniProtKB/Swiss-Prot: PSYR_HUMAN, Q8IYL9
    Tissue specificity: Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and
    peripheral blood leukocytes

        Pathway & Disease-focused RT2 Profiler PCR Array including GPR65: 
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for GPR65 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gpr651 , 5 G-protein coupled receptor 651, 5 78.21(n)1
    79.4(a)1
      12 (49.84 cM)5
    147441  NM_008152.31  NP_032178.11 
     982686575 
    chicken
    (Gallus gallus)
    Aves GPR651 G protein-coupled receptor 65 63.26(n)
    57.43(a)
      423395  XM_004941851.1  XP_004941908.1 
    lizard
    (Anolis carolinensis)
    Reptilia GPR656
    G protein-coupled receptor 65
    47(a)
    1 ↔ 1
    1(13960651-13961727)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gpr651 G protein-coupled receptor 65 56.51(n)
    46.98(a)
      100135008  XM_002933193.2  XP_002933239.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gpr656
    G protein-coupled receptor 65
    33(a)
    1 ↔ 1
    17(2588745-2595004) ENSDARG00000045957


    ENSEMBL Gene Tree for GPR65 (if available)
    TreeFam Gene Tree for GPR65 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GPR65 gene
    FFAR32  GPR42  GPR682  P2RY82  F2RL12  FFAR22  F2RL22  GPR422  
    GPR1322  FFAR12  F2RL32  F2R2  
    10 SIMAP similar genes for GPR65 using alignment to 2 protein entries:     PSYR_HUMAN (see all proteins):
    GPR68    GPR4    LPAR4    GPR17    LPAR6    CCR4
    P2RY1    PTAFR    GPR132    BDKRB2

    Find genes that share paralogs with GPR65           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GPR65 (see all 242)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1504582711,2
    --88469484(+) GTGTTA/GGGTCC 1 -- us2k10--------
    rs1889415501,2
    --88469638(+) CTAACC/TGTTCA 1 -- us2k10--------
    rs726920791,2
    C--88469639(+) TAACCA/GTTCAT 1 -- us2k10--------
    rs1828966971,2
    --88469706(+) AAGCAA/GATTTC 1 -- us2k10--------
    rs21655691,2
    C,F,H--88469786(+) CTCCTG/CTTTAA 1 -- us2k1 trp317Minor allele frequency- C:0.10NS EA NA WA CSA 795
    rs1872400521,2
    --88469825(+) TTTCTC/TAATGA 1 -- us2k10--------
    rs39436571,2
    C,F,H--88469829(+) TTAATT/GATAAT 1 -- us2k116Minor allele frequency- G:0.10NS EA NA WA CSA 791
    rs96719081,2
    C,F,A,H--88470049(+) AAAATG/TAGAAC 1 -- us2k119Minor allele frequency- T:0.36NS EA NA WA 2342
    rs1917565901,2
    --88470086(+) AAATCA/GTTACT 1 -- us2k10--------
    rs1425144461,2
    C--88470104(+) TTTGT-/AAAACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GPR65 (88471468 - 88481155 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for GPR65:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1389CNV Loss18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GPR65
    DNA2.0 Custom Variant and Variant Library Synthesis for GPR65

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604620    OMIM disorders: --


    Find genes that share disorders with GPR65           About GenesLikeMe

    3 Novoseek inferred disease relationships for GPR65 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ovarian cancer 41.6 3 19539899 (1), 15665078 (1), 15280385 (1)
    leukemia 16.5 1 9655242 (1)
    cancer 0 3 15221007 (2), 15618224 (1)

    Genetic Association Database (GAD): GPR65

    Export disorders for GPR65 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GPR65 gene, integrated from 10 sources (see all 26):
    (articles sorted by number of sources associating them with GPR65)
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    1. Cloning, characterization, and mapping of human homolog of mouse T- cell death-associated gene. (PubMed id 9655242)1, 2, 3, 9 Kyaw H.... Li Y. (DNA Cell Biol. 1998)
    2. Identification of a molecular target of psychosine and its role in globoid cell formation. (PubMed id 11309421)1, 2, 9 Im D.-S.... Lynch K.R. (J. Cell Biol. 2001)
    3. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. (PubMed id 21833088)1, 4  ....Compston A. (Nature 2011)
    4. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (PubMed id 21102463)1, 4 Franke A....Parkes M. (Nat. Genet. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (Nature 2003)
    7. Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor. (PubMed id 15618224)1, 9 Ishii S....Shimizu T. (J. Biol. Chem. 2005)
    8. G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers. (PubMed id 15221007)1, 9 Sin W.C....Yang J. (Oncogene 2004)
    9. Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells. (PubMed id 15665078)1, 9 Radu C.G....Witte O.N. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    10. Identification of GPR65, a novel regulator of matrix metalloproteinases using high through-put screening. (PubMed id 23707809)1 Xu H....Huang Z. (Biochem. Biophys. Res. Commun. 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 8477 HGNC: 4517 AceView: GPR65 Ensembl:ENSG00000140030 euGenes: HUgn8477
    ECgene: GPR65 H-InvDB: GPR65

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GPR65 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GPR65 gene:
    Search GeneIP for patents involving GPR65

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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