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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GPR183 Gene

protein-coding   GIFtS: 49
GCID: GC13M099946

G Protein-Coupled Receptor 183

(Previous name: Epstein-Barr virus induced gene 2 (lymphocyte-specific G...)
(Previous symbol: EBI2)
  Search for GPR183
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
G Protein-Coupled Receptor 1831 2
EBI21 2 3 5
EBV-Induced G-Protein Coupled Receptor 21 2 3
Epstein-Barr Virus Induced Gene 2 (Lymphocyte-Specific G Protein-Coupled
Receptor)1 2
Epstein-Barr Virus-Induced G-Protein Coupled Receptor 22 3
G-Protein Coupled Receptor 1832

External Ids:    HGNC: 31281   Entrez Gene: 18802   Ensembl: ENSG000001695087   OMIM: 6057415   UniProtKB: P322493   

Export aliases for GPR183 gene to outside databases

Previous GC identifers: GC13M098745 GC13M080541


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GPR183 Gene:
This gene was identified by the up-regulation of its expression upon Epstein-Barr virus infection of primary B
lymphocytes. This gene is predicted to encode a G protein-coupled receptor that is most closely related to the
thrombin receptor. Expression of this gene was detected in B-lymphocyte cell lines and lymphoid tissues but not
in T-lymphocyte cell lines or peripheral blood T lymphocytes. The function of this gene is unknown. (provided by
RefSeq, Jul 2008)

GeneCards Summary for GPR183 Gene: 
GPR183 (G protein-coupled receptor 183) is a protein-coding gene. GO annotations related to this gene include oxysterol binding and G-protein coupled receptor activity. An important paralog of this gene is P2RY4.

UniProtKB/Swiss-Prot: GP183_HUMAN, P32249
Function: Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols.
Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes
activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during
B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By
similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals
constitutively also via MAPK1/3 (ERK1/2)

Gene Wiki entry for GPR183 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000013.10  NC_018924.2  NT_009952.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GPR183 gene promoter:
         c-Fos   C/EBPbeta   AML1a   AP-1   C/EBPalpha   AREB6   PPAR-gamma1   POU2F1   PPAR-gamma2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGPR183 promoter sequence
   Search SABiosciences Chromatin IP Primers for GPR183

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPR183


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q32.3   Ensembl cytogenetic band:  13q32.3   HGNC cytogenetic band: 13q32.3

GPR183 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR183 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13M099946:  view genomic region     (about GC identifiers)

Start:
99,946,784 bp from pter      End:
99,959,749 bp from pter
Size:
12,966 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GP183_HUMAN, P32249 (See protein sequence)
Recommended Name: G-protein coupled receptor 183  
Size: 361 amino acids; 41224 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: GSK682753A
(8-[(2E)-3-(4-chlorophenyl)prop-2-enoyl]-3-[(3,4-dichlorophenyl)methyl]-1-oxa-3,8-diazaspiro[4.5]decan-2-one), an
inverse agonist, selectively inhibits the constitutive activity of GPR183 with high potency and efficacy
(PubMed:21673108)
Caution: It is uncertain whether Met-1 or Met-5 is the initiator
Secondary accessions: B2R8N5 Q53F99 Q5JUH7

Explore the universe of human proteins at neXtProt for GPR183: NX_P32249

Explore proteomics data for GPR183 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P32249

  • GPR183 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GPR183 Protein Expression
    REFSEQ proteins: NP_004942.1  
    ENSEMBL proteins: 
     ENSP00000365596  

    Human Recombinant Protein Products for GPR183: 
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    Novus Biologicals GPR183 Protein
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    Cloud-Clone Corp. Proteins for GPR183 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IDA--
    GO:0005887integral to plasma membrane TAS8383238
    GO:0016021integral to membrane ----

    GPR183 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GPCRAO: GPCR / Class A : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: GPR183 
    Class A Orphans

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002286 purinergic_P2Y_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry P32249

    ProtoNet protein and cluster: P32249

    UniProtKB/Swiss-Prot: GP183_HUMAN, P32249
    Similarity: Belongs to the G-protein coupled receptor 1 family


    GPR183 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GP183_HUMAN, P32249
    Function: Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols.
    Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses. Promotes
    activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during
    B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By
    similarity). Signals constitutively through G(i)-alpha, but not through G(s)-alpha or G(q)-alpha. Signals
    constitutively also via MAPK1/3 (ERK1/2)
    Induction: By Epstein-Barr virus (EBV)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
    GO:0008142oxysterol binding IDA--
    GO:0045028G-protein coupled purinergic nucleotide receptor activity ----
         
    GPR183 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Gpr183):
     cellular  hematopoietic system  immune system  no phenotypic analysis 

    GPR183 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Gpr183tm1.2Rbr for GPR183

       inGenious Targeting Laboratory - Custom generated mouse model solutions for GPR183 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GPR183

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GPR183 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GPR183 

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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate GPR183:
    hsa-miR-144 hsa-miR-2117 hsa-miR-3143
    SwitchGear 3'UTR luciferase reporter plasmidGPR183 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR183


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GPR183 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1GPCRs, Other
    GPCRs, Other


    1 BioSystems Pathway for GPR183
        GPCRs, Other


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPR183

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for GPR183 (P322492, 3 ENSP000003655964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MTA1Q133302, 3, ENSP000003336334MINT-63668 I2D: score=5 STRING: ENSP00000333633
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002313mature B cell differentiation involved in immune response ISS--
    GO:0006955immune response TAS8383238
    GO:0006959humoral immune response ISS--
    GO:0007186G-protein coupled receptor signaling pathway IDA--
    GO:0030890positive regulation of B cell proliferation IDA--

    GPR183 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GPR183 (GP183)

    8 IUPHAR Ligands for GPR183 (GPR183)    About this table 
    LigandTypeActionAffinityPubmed IDs
    7α,25-dihydroxycholesterol
    AgonistFull agonist8.1 - 9.8521796211 21796212
    7α,27-dihydroxycholesterol
    AgonistAgonist8.8921796211
    7β, 25-dihydroxycholesterol
    AgonistAgonist8.6821796211
    7β, 27-dihydroxycholesterol
    AgonistAgonist7.2921796211
    7α-hydroxycholesterol
    AgonistAgonist7.0921796211
    25-hydroxycholesterol
    AgonistAgonist6.921796211
    7β-hydroxycholesterol
    AgonistAgonist5.7521796211
    27-hydroxycholesterol
    AgonistAgonist5.5221796211

    Search CenterWatch for drugs/clinical trials and news about GPR183 / GP183

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GPR183 gene: 
    NM_004951.4  

    Unigene Cluster for GPR183:

    G protein-coupled receptor 183
    Hs.784  [show with all ESTs]
    Unigene Representative Sequence: NM_004951
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000376414(uc001vog.3)
    miRNA
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    hsa-miR-144 hsa-miR-2117 hsa-miR-3143
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK223390.1 AK292091.1 AK313443.1 BC020752.1 L08177.1 

    7 DOTS entries:

    DT.100775387  DT.110848  DT.100775386  DT.92034996  DT.100650201  DT.120766180  DT.120766226 

    24/90 AceView cDNA sequences (see all 90):

    CR614065 CR597919 NM_004951 BC020752 CR592718 AW574697 BQ003741 BP367552 
    T29782 CR609579 AL547762 AL532537 BM128329 BX417963 H88656 BX279588 
    AI697249 BG536922 BI517811 CD521751 AV758010 AL709174 BM549799 CD619478 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GPR183 expression in normal human tissues (normalized intensities)      GPR183 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAAGGGTAT
    GPR183 Expression
    About this image


    GPR183 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/11 selected tissues (see all 11) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 9 entries
             Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
             Peripheral blood Pan-T Cells   
     
     Kidney (Urinary System)    fully expand to see all 4 entries
             Metanephric Mesenchyme Cells Metanephric Mesenchyme
             Metanephros
             visceral organ/mesentery/urogenital mesentery   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 4 entries
             Cord Blood CD133- Cells   
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 3 entries
             visceral organ/urogenital sinus/primitive bladder   
     
     Thymus (Hematopoietic System)
             T Helper Cells Thymus

    See GPR183 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GPR183

    SOURCE GeneReport for Unigene cluster: Hs.784

    UniProtKB/Swiss-Prot: GP183_HUMAN, P32249
    Tissue specificity: Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and
    T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the
    urogenital system and brain

        SABiosciences Expression via Pathway-Focused PCR Array including GPR183: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR183

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GPR183 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gpr1831 , 5 G protein-coupled receptor 1831, 5 81.89(n)1
    87.96(a)1
      14 (65.86 cM)5
    3210191  NM_183031.21  NP_898852.21 
     1219523315 
    chicken
    (Gallus gallus)
    Aves GPR1831 G protein-coupled receptor 183 71.6(n)
    70.71(a)
      769212  XM_001231943.1  XP_001231944.1 
    lizard
    (Anolis carolinensis)
    Reptilia GPR1836
    --
    Uncharacterized protein
    61(a)
    22(a)
    1 ↔ 1
    possible ortholog
    3(98798458-98799570)
    GL343558.1(383891-384853)
    zebrafish
    (Danio rerio)
    Actinopterygii gpr1836
    GPR183 (3 of 3)6
    (see all 3)
    G protein-coupled receptor 183
    (see all 3)
    51(a)
    47(a)
    (see all 3)
    1 ↔ many
    1 ↔ many
    (see all 3)
    9(32138697-32141593)
    1(29608553-29611238)


    ENSEMBL Gene Tree for GPR183 (if available)
    TreeFam Gene Tree for GPR183 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GPR183 gene
    P2RY42  CYSLTR12  LPAR42  CYSLTR22  P2RY22  PTAFR2  OXGR12  P2RY112  
    P2RY12  GPR172  P2RY62  GPR1742  LPAR62  LPAR52  P2RY102  SUCNR12  
    18/33 SIMAP similar genes for GPR183 using alignment to 1 protein entry:     GP183_HUMAN(see all similar genes):
    CYSLTR1    GPR17    CCR5    LPAR6    P2RY5    CCR8
    CYSLTR2    KPG_011    LPAR4    CCR1    P2RY1    P2RY13
    P2RY8    GPR174    P2RY12    P2RY14    AGTR1    CCR9

    GPR183 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GPR183
    PGOHUM00000248479


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1 SNPs in GPR183 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0541474
    An acute myeloid leukemia sample4--see VAR_0541472 A V mis40--------

    HapMap Linkage Disequilibrium report for GPR183 (99946784 - 99959749 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GPR183: --
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GPR183 for disorders           About MalaCards
    OMIM gene information: 605741    OMIM disorders: --


    GPR183 for disorders           About GeneDecksing


    Export disorders for GPR183 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GPR183 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with GPR183)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors. (PubMed id 8383238)1, 2, 3 Birkenbach M.P....Kieff E. (1993)
    2. Molecular pharmacological phenotyping of EBI2. An orphan seven- transmembrane receptor with constitutive activity. (PubMed id 16540462)1, 2 Rosenkilde M.M....Schwartz T.W. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Chronic rhinosinusitis with nasal polyps is characteri zed by B-cell inflammation and EBV-induced protein 2 expression. (PubMed id 23473835)1 Hulse K.E....Schleimer R.P. (2013)
    5. EBI2 regulates CXCL13-mediated responses by heterodime rization with CXCR5. (PubMed id 22913878)1 Barroso R....Mellado M. (2012)
    6. Host-microbe interactions have shaped the genetic arch itecture of inflammatory bowel disease. (PubMed id 23128233)1 Jostins L....Cho J.H. (2012)
    7. Identification of structural motifs critical for epste in-barr virus-induced molecule 2 function and homology modeling of the ligand do cking site. (PubMed id 22930711)1 Zhang L....Liu C. (2012)
    8. Molecular characterization of oxysterol binding to the Epstein-Barr virus-induced gene 2 (GPR183). (PubMed id 22875855)1 Benned-Jensen T....Rosenkilde M.M. (2012)
    9. Ligand modulation of the Epstein-Barr virus-induced seven- transmembrane receptor EBI2: identification of a potent and efficacious inverse agonist. (PubMed id 21673108)2 Benned-Jensen T.... Rosenkilde M.M. (2011)
    10. EBI2, GPR18 and GPR17--three structurally related, bu t biologically distinct 7TM receptors. (PubMed id 21261596)1 NA...Rosenkilde M.M. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1880 HGNC: 3128 AceView: EBI2 Ensembl:ENSG00000169508 euGenes: HUgn1880
    ECgene: GPR183 H-InvDB: GPR183

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GPR183 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GPR183 gene:
    Search GeneIP for patents involving GPR183

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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