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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GPR17 Gene

protein-coding   GIFtS: 57
GCID: GC02P128403

G Protein-Coupled Receptor 17

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
G Protein-Coupled Receptor 171 2
R122 3
G-Protein Coupled Receptor 172 3
P2Y-Like Receptor2 3
UDP/CysLT Receptor2 3
Uracil Nucleotide/Cysteinyl Leukotriene Receptor2

External Ids:    HGNC: 44711   Entrez Gene: 28402   Ensembl: ENSG000001442307   OMIM: 6030715   UniProtKB: Q133043   

Export aliases for GPR17 gene to outside databases

Previous GC identifers: GC02P125701 GC02P126328 GC02P128308 GC02P128497 GC02P128119 GC02P120709


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for GPR17 Gene: 
GPR17 (G protein-coupled receptor 17) is a protein-coding gene. Diseases associated with GPR17 include suppression amblyopia, and amblyopia, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and Signaling by GPCR. GO annotations related to this gene include G-protein coupled purinergic nucleotide receptor activity and chemokine receptor activity. An important paralog of this gene is OXGR1.

UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through
G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia

Gene Wiki entry for GPR17 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022135.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GPR17 gene promoter:
         c-Fos   AP-1   Pax-5   Lmo2   NF-kappaB   HEN1   NF-kappaB2   c-Jun   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGPR17 promoter sequence
   Search SABiosciences Chromatin IP Primers for GPR17

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPR17


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q21   Ensembl cytogenetic band:  2q14.3   HGNC cytogenetic band: 2q21

GPR17 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR17 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P128403:  view genomic region     (about GC identifiers)

Start:
128,403,439 bp from pter      End:
128,410,213 bp from pter
Size:
6,775 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304 (See protein sequence)
Recommended Name: Uracil nucleotide/cysteinyl leukotriene receptor  
Size: 367 amino acids; 40989 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: A8K9L0 B2R9X0 Q8N5S7 Q9UDZ6 Q9UE21
Alternative splicing: 2 isoforms:  Q13304-1   Q13304-2   

Explore the universe of human proteins at neXtProt for GPR17: NX_Q13304

Explore proteomics data for GPR17 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13304

  • GPR17 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GPR17 Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001154887.1  NP_001154888.1  NP_001154889.1  NP_005282.1  

    ENSEMBL proteins: 
     ENSP00000272644   ENSP00000387970   ENSP00000376741   ENSP00000442982  
    Reactome Protein details: Q13304
    Human Recombinant Protein Products for GPR17: 
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    Cloud-Clone Corp. Proteins for GPR17 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS8558062
    GO:0016021integral to membrane ----

    GPR17 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    GPCRAO: GPCR / Class A : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: GPR17 
    Class A Orphans

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR002286 purinergic_P2Y_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q13304

    ProtoNet protein and cluster: Q13304

    1 Blocks protein domain: IPB002286 P2 purinoceptor signature

    UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
    Similarity: Belongs to the G-protein coupled receptor 1 family


    GPR17 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GPR17_HUMAN, Q13304
    Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through
    G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0004950chemokine receptor activity TAS8558062
    GO:0045028G-protein coupled purinergic nucleotide receptor activity ----
         
    GPR17 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GPR17:
     Increased circadian period len 

         3 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Gpr17):
     behavior/neurological  cardiovascular system  nervous system 

    GPR17 for phenotypes           About GeneDecksing

    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GPR17 About   (see all 6)                                                                                              See pathways by source

    SuperPathContained pathways About
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    G alpha (i) signalling events0.46
    GPCR ligand binding0.71
    GPCRs, Class A Rhodopsin-like0.41
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3G alpha (q) signalling events
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    G alpha (q) signalling events0.90
    4Nucleotide-like (purinergic) receptors
    Nucleotide-like (purinergic) receptors0.75
    P2Y receptors0.75
    5Prostanoid ligand receptors
    Eicosanoid ligand-binding receptors0.60
    Leukotriene receptors0.33

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 BioSystems Pathways for GPR17
        GPCRs, Other
    GPCRs, Class A Rhodopsin-like

    5/12        Reactome Pathways for GPR17 (see all 12)
        GPCR downstream signaling
    Eicosanoid ligand-binding receptors
    P2Y receptors
    Leukotriene receptors
    Gastrin-CREB signalling pathway via PKC and MAPK



    GPR17 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPR17

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/247 Interacting proteins for GPR17 (Q133043 ENSP000002726444) via UniProtKB, MINT, STRING, and/or I2D (see all 247)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNA13Q143443, ENSP000004007174I2D: score=2 STRING: ENSP00000400717
    ADCY1ENSP000002973234STRING: ENSP00000297323
    ADCY2ENSP000003429524STRING: ENSP00000342952
    APLNRENSP000002572544STRING: ENSP00000257254
    CCKENSP000003356574STRING: ENSP00000335657
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS8558062
    GO:0070098chemokine-mediated signaling pathway TAS8558062

    GPR17 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GPR17

    1 HMDB Compound for GPR17    About this table
    CompoundSynonyms CAS #PubMed Ids
    Uracil2,4-Dihydroxypyrimidine (see all 8)66-22-8--

    10/11 IUPHAR Ligands for GPR17 (GPR17) (see all 11)    About this table 
    LigandTypeActionAffinityPubmed IDs
    ASN04885796
    AgonistAgonist9.9621744154
    ASN02563583
    AgonistAgonist9.9621744154
    ASN06917370
    AgonistAgonist9.5721744154
    UDP-glucose
    AgonistAgonist5.92 - 9.5220148890 16990797
    LTC4
    AgonistAgonist7.83 - 9.4816990797
    ASN04450772
    AgonistAgonist8.9321744154
    UDP-galactose
    AgonistAgonist5.96 - 8.9220148890 16990797
    UDP
    AgonistAgonist5.97 - 8.820148890 16990797
    ASN04421891
    AgonistAgonist8.4421744154
    LTD4
    AgonistAgonist8.14 - 8.3616990797

    Search CenterWatch for drugs/clinical trials and news about GPR17

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GPR17 gene (4 alternative transcripts): 
    NM_001161415.1  NM_001161416.1  NM_001161417.1  NM_005291.2  

    Unigene Clusters for GPR17:

    G protein-coupled receptor 17
    Hs.46453  [show with all ESTs], Hs.736277  [show with all ESTs]
    Unigene Representative Sequences: AK126849, BX538082
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000496086 ENST00000486700 ENST00000272644 ENST00000423019 ENST00000393018
    ENST00000544369(uc010yzn.2 uc002tpc.3 uc010yzo.2 uc002tpd.3)

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    hsa-miR-9*
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    Additional mRNA sequence: BX538082.1 

    9 DOTS entries:

    DT.92428447  DT.114539  DT.101985303  DT.105541  DT.40125549  DT.121020343  DT.91875438  DT.100024465 
    DT.454095 

    24/123 AceView cDNA sequences (see all 123):

    AA309544 BG818500 BF345709 N63411 BF345996 BC013202 BF527616 NM_005291 
    AA297795 AI417819 BC039595 AI953187 AA862286 BF530988 BG912322 AI378784 
    BF345843 BG911003 Y12546 BG820495 AI382504 BF530270 BF345969 BG818910 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GPR17 expression in normal human tissues (normalized intensities)      GPR17 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACATCGATGT
    GPR17 Expression
    About this image


    GPR17 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Pre-myelinating Oligodendrocyte Cells Forebrain White Matter
             Medulla Oblongata
     
     Spinal Cord (Nervous System)    fully expand to see all 3 entries
             Pre-myelinating Oligodendrocyte Cells Spinal Cord White Matter
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Chondrocytes Zeugopod Epiphyseal End
             Zeugopod Growth Plate
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Oligodendrocyte Precursor Cells Motor Neural Progenitor Domain
             Spinal Ventral Columns
     
     Cartilage (Muscoskeletal System)
             Chondrocytes Zeugopod Epiphyseal End

    See GPR17 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GPR17

    SOURCE GeneReport for Unigene clusters: Hs.46453 Hs.736277

    UniProtKB/Swiss-Prot: GPR17_HUMAN, Q13304
    Tissue specificity: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain

        SABiosciences Expression via Pathway-Focused PCR Arrays including GPR17: 
              G Protein Coupled Receptors 384HT in human mouse rat
              Chemokines & Receptors in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR17

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GPR17 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gpr171 , 5 G protein-coupled receptor 171, 5 84.37(n)1
    90.27(a)1
      18 (17.89 cM)5
    5744021  NM_001025381.21  NP_001020552.11 
     319429975 
    chicken
    (Gallus gallus)
    Aves GPR171 G protein-coupled receptor 17 74.01(n)
    79.82(a)
      769024  XM_001231869.1  XP_001231870.1 
    lizard
    (Anolis carolinensis)
    Reptilia GPR176
    G protein-coupled receptor 17
    74(a)
    1 ↔ 1
    3(36212139-36221708)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003318411 uracil nucleotide/cysteinyl leukotriene receptor-like 59.25(n)
    57.01(a)
      100331841  XM_002662449.2  XP_002662495.2 


    ENSEMBL Gene Tree for GPR17 (if available)
    TreeFam Gene Tree for GPR17 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GPR17 gene
    OXGR12  P2RY42  P2RY12  P2RY112  P2RY62  GPR1742  LPAR62  LPAR52  
    CYSLTR12  GPR1832  LPAR42  CYSLTR22  P2RY22  SUCNR12  P2RY102  PTAFR2  
    18/49 SIMAP similar genes for GPR17 using alignment to 3 protein entries:     GPR17_HUMAN (see all proteins) (see all similar genes):
    DKFZp686M18273    CYSLTR1    P2RY1    LPAR4    CXCR7    CYSLTR2
    KPG_011    CCR-5    GPR183    LPAR6    P2RY5    CCR8
    GPR18    AGTR1    CCR2    F2RL1    GPR171    GPR34

    GPR17 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section
    Structural Variations
         Database of Genomic Variants (DGV) 10/14 variations for GPR17 (see all 14):    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv508864CNV Insertion20534489
    nsv517532CNV Loss19592680
    dgv4298n71CNV Loss21882294
    nsv875030CNV Loss21882294
    nsv470482CNV Loss18288195
    dgv4301n71CNV Loss21882294
    nsv518085CNV Loss19592680
    dgv4300n71CNV Loss21882294
    nsv875031CNV Loss21882294
    nsv875015CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603071    OMIM disorders: --

    5 diseases for GPR17:    About MalaCards
    suppression amblyopia    amblyopia    spinal cord injury    ischemia
    endotheliitis

    1 disease from the University of Copenhagen DISEASES database for GPR17:
    Suppression amblyopia

    GPR17 for disorders           About GeneDecksing


    Export disorders for GPR17 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GPR17 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with GPR17)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. New members of the chemokine receptor gene family. (PubMed id 8558062)1, 2, 3 Raport C.J.... Gray P.W. (1996)
    2. The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor. (PubMed id 16990797)1, 2 Ciana P.... Abbracchio M.P. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21. (PubMed id 9523551)1, 2 Blaesius R.H.... Ogilvie A. (1998)
    5. The regulated expression, intracellular trafficking, a nd membrane recycling of the P2Y-like receptor GPR17 in Oli-neu oligodendroglial cells. (PubMed id 23288840)1 Fratangeli A....Rosa P. (2013)
    6. Agonist-induced desensitization/resensitization of hu man G protein-coupled receptor 17: a functional cross-talk between purinergic a nd cysteinyl-leukotriene ligands. (PubMed id 21531793)1 Daniele S....Martini C. (2011)
    7. EBI2, GPR18 and GPR17--three structurally related, bu t biologically distinct 7TM receptors. (PubMed id 21261596)1 NA...Rosenkilde M.M. (2011)
    8. Distinct expression and ligand-binding profiles of tw o constitutively active GPR17 splice variants. (PubMed id 20148890)1 Benned-Jensen T. and Rosenkilde M.M. (2010)
    9. Functional characterization of two isoforms of the P2 Y-like receptor GPR17: [35S]GTPgammaS binding and electrophysiological studies in 1321N1 cells. (PubMed id 19625605)1 Pugliese A.M....Abbracchio M.P. (2009)
    10. GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. (PubMed id 18533035)1 Parravicini C....Fantucci P. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2840 HGNC: 4471 AceView: GPR17 Ensembl:ENSG00000144230 euGenes: HUgn2840
    ECgene: GPR17 H-InvDB: GPR17

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GPR17 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GPR17 gene:
    Search GeneIP for patents involving GPR17

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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