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Aliases for GPR160 Gene

Aliases for GPR160 Gene

  • G Protein-Coupled Receptor 160 2 3 5
  • G-Protein Coupled Receptor GPCR1 3 4
  • GPCR150 3 4
  • HGPCR1 3 4
  • Probable G-Protein Coupled Receptor 160 3
  • Putative G Protein-Coupled Receptor 3
  • GPCR1 3

External Ids for GPR160 Gene

Previous GeneCards Identifiers for GPR160 Gene

  • GC03P171076
  • GC03P171238
  • GC03P169755
  • GC03P167126

Summaries for GPR160 Gene

GeneCards Summary for GPR160 Gene

GPR160 (G Protein-Coupled Receptor 160) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity.

UniProtKB/Swiss-Prot for GPR160 Gene

  • Orphan receptor.

Gene Wiki entry for GPR160 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR160 Gene

Genomics for GPR160 Gene

Regulatory Elements for GPR160 Gene

Enhancers for GPR160 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G170043 1.9 FANTOM5 Ensembl ENCODE dbSUPER 38 +9.7 9680 7.8 HDGF PKNOX1 FOXA2 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 FEZF1 GPR160 LOC100128164 SEC62 LRRC34 LRRIQ4 SEC62-AS1 SKIL GC03P170058
GH03G170037 1.3 ENCODE dbSUPER 39.2 +2.2 2208 4.8 FOXA2 PKNOX1 ARID4B SIN3A DMAP1 ZNF2 SLC30A9 ZNF766 ZNF143 FOS GPR160 GC03P170058
GH03G170153 1.4 Ensembl ENCODE dbSUPER 35.4 +117.3 117283 2.1 HDAC1 HDGF TBP PKNOX1 TCF12 CBX5 RELB IKZF2 CREM GATAD2B GPR160 GC03P170151 RNU7-32P
GH03G170127 1.2 ENCODE dbSUPER 33.3 +91.0 90966 2.9 HDGF PKNOX1 TBL1XR1 CBX5 SCRT2 KLF7 RELB CREM IKZF2 ZNF263 GPR160 GC03M170140 LOC105374209
GH03G170178 1.3 ENCODE dbSUPER 30.5 +143.0 143006 3.9 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B YY1 ZNF766 ZNF143 GPR160 PRKCI ENSG00000270096 PHC3 GC03P170161
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPR160 on UCSC Golden Path with GeneCards custom track

Promoters for GPR160 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000161564 857 1601 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 ZNF48 SLC30A9 ZNF766 GLIS2

Genomic Location for GPR160 Gene

Chromosome:
3
Start:
170,037,543 bp from pter
End:
170,085,418 bp from pter
Size:
47,876 bases
Orientation:
Plus strand

Genomic View for GPR160 Gene

Genes around GPR160 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPR160 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPR160 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR160 Gene

Proteins for GPR160 Gene

  • Protein details for GPR160 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJ42-GP160_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 160
    Protein Accession:
    Q9UJ42
    Secondary Accessions:
    • D3DNQ2

    Protein attributes for GPR160 Gene

    Size:
    338 amino acids
    Molecular mass:
    39787 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPR160 Gene

Post-translational modifications for GPR160 Gene

  • Glycosylation at isoforms=8
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPR160 Gene

Domains & Families for GPR160 Gene

Gene Families for GPR160 Gene

Protein Domains for GPR160 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPR160 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UJ42

UniProtKB/Swiss-Prot:

GP160_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with GPR160: view

Function for GPR160 Gene

Molecular function for GPR160 Gene

UniProtKB/Swiss-Prot Function:
Orphan receptor.

Gene Ontology (GO) - Molecular Function for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with GPR160: view
genes like me logo Genes that share phenotypes with GPR160: view

Animal Model Products

  • Taconic Biosciences Mouse Models for GPR160

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GPR160 Gene

Localization for GPR160 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR160 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPR160 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IDA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0043235 receptor complex IDA 23382219
genes like me logo Genes that share ontologies with GPR160: view

Pathways & Interactions for GPR160 Gene

SuperPathways for GPR160 Gene

No Data Available

Interacting Proteins for GPR160 Gene

Gene Ontology (GO) - Biological Process for GPR160 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with GPR160: view

No data available for Pathways by source and SIGNOR curated interactions for GPR160 Gene

Transcripts for GPR160 Gene

Unigene Clusters for GPR160 Gene

G protein-coupled receptor 160:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPR160 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c
SP1: - - - - - - - -
SP2: - - - - - -
SP3:
SP4: - - - - -
SP5: - - - -
SP6:

Relevant External Links for GPR160 Gene

GeneLoc Exon Structure for
GPR160
ECgene alternative splicing isoforms for
GPR160

Expression for GPR160 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GPR160 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GPR160 Gene

This gene is overexpressed in Whole Blood (x11.5) and Colon - Transverse (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of GPR160 Gene:

GPR160

SOURCE GeneReport for Unigene cluster for GPR160 Gene:

Hs.231320

Evidence on tissue expression from TISSUES for GPR160 Gene

  • Pancreas(4.2)
  • Stomach(2)
genes like me logo Genes that share expression patterns with GPR160: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPR160 Gene

Orthologs for GPR160 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPR160 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR160 34 35
  • 99.6 (n)
dog
(Canis familiaris)
Mammalia GPR160 34 35
  • 89.25 (n)
cow
(Bos Taurus)
Mammalia GPR160 34 35
  • 86.75 (n)
rat
(Rattus norvegicus)
Mammalia Gpr160 34
  • 74.8 (n)
mouse
(Mus musculus)
Mammalia Gpr160 34 16 35
  • 73.31 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia GPR160 35
  • 55 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPR160 35
  • 41 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPR160 34 35
  • 60.22 (n)
lizard
(Anolis carolinensis)
Reptilia GPR160 35
  • 44 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr160 34
  • 53.99 (n)
MGC76104 34
African clawed frog
(Xenopus laevis)
Amphibia gpcr1-A 34
zebrafish
(Danio rerio)
Actinopterygii gpr160 34 35
  • 45.16 (n)
Species where no ortholog for GPR160 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR160 Gene

ENSEMBL:
Gene Tree for GPR160 (if available)
TreeFam:
Gene Tree for GPR160 (if available)

Paralogs for GPR160 Gene

Pseudogenes.org Pseudogenes for GPR160 Gene

genes like me logo Genes that share paralogs with GPR160: view

No data available for Paralogs for GPR160 Gene

Variants for GPR160 Gene

Sequence variations from dbSNP and Humsavar for GPR160 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000030836 -- 170,041,073(+) TCTGA(C/G)AGGGA intron-variant
rs1000057285 -- 170,038,669(+) GCGCG(C/T)GCGTG intron-variant
rs1000077320 -- 170,038,006(+) CCTGG(C/T)CTGGA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime
rs1000118382 -- 170,045,479(+) GCCTG(C/T)AGTCC intron-variant
rs1000195728 -- 170,037,765(+) GTCCT(C/T)AAGAT nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for GPR160 Gene

Variant ID Type Subtype PubMed ID
dgv8728n54 CNV loss 21841781
esv2726189 CNV deletion 23290073
nsv1009884 CNV gain 25217958
nsv7356 OTHER inversion 18451855

Variation tolerance for GPR160 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.33% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPR160 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPR160

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR160 Gene

Disorders for GPR160 Gene

Relevant External Links for GPR160

Genetic Association Database (GAD)
GPR160
Human Genome Epidemiology (HuGE) Navigator
GPR160
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPR160

No disorders were found for GPR160 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR160 Gene

Publications for GPR160 Gene

  1. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 2 3 4 64
  2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PMID: 19851296) Oguri M. … Yamada Y. (Am. J. Hypertens. 2010) 3 46 64
  3. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PMID: 20198315) Yoshida T. … Yamada Y. (Int. J. Mol. Med. 2010) 3 46 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. Mining of assembled expressed sequence tag (EST) data for protein families: application to the G protein-coupled receptor superfamily. (PMID: 11466977) Conklin D. … Vissing H. (Brief. Bioinform. 2000) 3 4 64

Products for GPR160 Gene

Sources for GPR160 Gene

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