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Aliases for GPR155 Gene

Aliases for GPR155 Gene

  • G Protein-Coupled Receptor 155 2 3 5
  • G-Protein Coupled Receptor PGR22 3 4
  • PGR22 3 4
  • Integral Membrane Protein GPR155 3
  • DEPDC3 3
  • DEP.7 3

External Ids for GPR155 Gene

Previous GeneCards Identifiers for GPR155 Gene

  • GC02M175500
  • GC02M175124
  • GC02M175004
  • GC02M175296
  • GC02M167176

Summaries for GPR155 Gene

GeneCards Summary for GPR155 Gene

GPR155 (G Protein-Coupled Receptor 155) is a Protein Coding gene.

Gene Wiki entry for GPR155 Gene

Additional gene information for GPR155 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR155 Gene

Genomics for GPR155 Gene

Regulatory Elements for GPR155 Gene

Enhancers for GPR155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H174338 2.7 VISTA Ensembl ENCODE 8 +146.1 146070 5 PKNOX1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 SLC30A9 ZNF143 ZNF202 MXD4 GPR155 LOC102724194 GC02P174342
GH02H174331 1.9 VISTA 8.1 +155.2 155244 1.1 ZNF362 RNF2 SUZ12 BMI1 ZFP69B ZNF692 SMARCA4 KDM1A EZH2 GPR155 SP9 LINC01305
GH02H174334 1.3 Ensembl ENCODE 8.6 +150.8 150849 4.2 HDGF PKNOX1 ATF1 ARNT ARID4B SIN3A FEZF1 GLIS2 ZNF202 SP3 GPR155 SCRN3 SP9 LOC102724194
GH02H174492 1.3 FANTOM5 Ensembl ENCODE 8 -6.6 -6615 3.4 HDGF TBL1XR1 RBBP5 YY1 ZNF207 ATF7 RUNX3 IKZF2 CREM SMARCA5 WIPF1 GPR155 CIR1 GC02M174489 LOC442058
GH02H174585 1.6 FANTOM5 ENCODE dbSUPER 6.5 -106.5 -106521 17 HDGF PKNOX1 FOXA2 ATF1 SIN3A FEZF1 YY1 ZNF207 FOS ATF7 WIPF1 CIR1 GPR155 ENSG00000237798 GC02P174645
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPR155 on UCSC Golden Path with GeneCards custom track

Promoters for GPR155 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000126581 294 2401 ATF1 ARNT SIN3A DMAP1 ZNF2 YY1 ZNF121 GLIS2 ELK1 ZNF143

Genomic Locations for GPR155 Gene

Genomic Locations for GPR155 Gene
55,524 bases
Minus strand

Genomic View for GPR155 Gene

Genes around GPR155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPR155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPR155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR155 Gene

Proteins for GPR155 Gene

  • Protein details for GPR155 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Integral membrane protein GPR155
    Protein Accession:
    Secondary Accessions:
    • B2RCI2
    • D3DPE2
    • Q4G0Y6
    • Q53SJ3
    • Q53TA8
    • Q69YG8
    • Q86SP9
    • Q8N261
    • Q8N639
    • Q8N8K3
    • Q96MV6

    Protein attributes for GPR155 Gene

    870 amino acids
    Molecular mass:
    96919 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB71170.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for GPR155 Gene

Post-translational modifications for GPR155 Gene

  • Glycosylation at posLast=99, posLast=1515, posLast=2929, isoforms=198, isoforms=309, posLast=381381, isoforms=543, and isoforms=612
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPR155 Gene

Domains & Families for GPR155 Gene

Gene Families for GPR155 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for GPR155 Gene

Suggested Antigen Peptide Sequences for GPR155 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GPR155: view

No data available for UniProtKB/Swiss-Prot for GPR155 Gene

Function for GPR155 Gene

Gene Ontology (GO) - Molecular Function for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with GPR155: view
genes like me logo Genes that share phenotypes with GPR155: view

Animal Model Products

miRNA for GPR155 Gene

miRTarBase miRNAs that target GPR155

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPR155 Gene

Localization for GPR155 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR155 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPR155 gene
Compartment Confidence
extracellular 5
plasma membrane 3
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear bodies (1)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005737 cytoplasm IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with GPR155: view

Pathways & Interactions for GPR155 Gene

SuperPathways for GPR155 Gene

No Data Available

Interacting Proteins for GPR155 Gene

Selected Interacting proteins: Q7Z3F1-GP155_HUMAN for GPR155 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035556 intracellular signal transduction IEA --
GO:0050890 cognition IMP 17519220
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with GPR155: view

No data available for Pathways by source and SIGNOR curated interactions for GPR155 Gene

Drugs & Compounds for GPR155 Gene

No Compound Related Data Available

Transcripts for GPR155 Gene

Unigene Clusters for GPR155 Gene

G protein-coupled receptor 155:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPR155 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP3: -
SP4: -
SP5: - -

Relevant External Links for GPR155 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GPR155 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GPR155 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for GPR155 Gene

This gene is overexpressed in Urine (65.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GPR155 Gene

Protein tissue co-expression partners for GPR155 Gene

NURSA nuclear receptor signaling pathways regulating expression of GPR155 Gene:


SOURCE GeneReport for Unigene cluster for GPR155 Gene:


Evidence on tissue expression from TISSUES for GPR155 Gene

  • Nervous system(4.2)
  • Eye(4.1)
genes like me logo Genes that share expression patterns with GPR155: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPR155 Gene

Orthologs for GPR155 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPR155 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia GPR155 33 34
  • 99.6 (n)
(Canis familiaris)
Mammalia GPR155 33 34
  • 93.26 (n)
(Bos Taurus)
Mammalia GPR155 33 34
  • 91.98 (n)
(Mus musculus)
Mammalia Gpr155 33 16 34
  • 85.68 (n)
(Rattus norvegicus)
Mammalia Gpr155 33
  • 85.64 (n)
(Monodelphis domestica)
Mammalia GPR155 34
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia GPR155 34
  • 82 (a)
(Gallus gallus)
Aves GPR155 33 34
  • 74.96 (n)
(Anolis carolinensis)
Reptilia GPR155 34
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr155 33
  • 68.28 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.19272 33
(Danio rerio)
Actinopterygii gpr155a 33 34
  • 60.06 (n)
gpr155b 34
  • 56 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7510 33 34
  • 46.19 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006992 33
  • 45.63 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 40 (a)
Species where no ortholog for GPR155 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR155 Gene

Gene Tree for GPR155 (if available)
Gene Tree for GPR155 (if available)

Paralogs for GPR155 Gene

No data available for Paralogs for GPR155 Gene

Variants for GPR155 Gene

Sequence variations from dbSNP and Humsavar for GPR155 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000030773 -- 174,492,699(+) AATAT(A/T)CATAT intron-variant
rs1000060635 -- 174,477,227(+) TAATG(A/T)TTTAA intron-variant
rs1000125780 -- 174,479,254(+) CAATA(C/G)ATTAA intron-variant
rs1000134341 -- 174,449,976(+) TCTCA(-/AAAAC)AAAAC intron-variant
rs1000205208 -- 174,455,476(+) AGGAG(A/C/G)CTGAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GPR155 Gene

Variant ID Type Subtype PubMed ID
nsv583667 CNV loss 21841781
nsv526187 CNV loss 19592680
esv3893507 CNV loss 25118596

Variation tolerance for GPR155 Gene

Residual Variation Intolerance Score: 7.31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.04; 37.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPR155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR155 Gene

Disorders for GPR155 Gene

Relevant External Links for GPR155

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GPR155 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR155 Gene

Publications for GPR155 Gene

  1. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis DK … Gaitanaris GA (Proceedings of the National Academy of Sciences of the United States of America 2003) 2 3 4 60
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 60
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 3 4 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for GPR155 Gene

Sources for GPR155 Gene

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