GPR155 Gene
protein-coding GIFtS: 43
GCID: GC02M175296
|
|
G protein-coupled receptor 155
| |
Aliases
for GPR155 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| G Protein-Coupled Receptor 1551 2 | | G-Protein Coupled Receptor PGR222 3 | | PGR221 2 3 | | FLJ318191 | | DEP.71 2 | | Integral Membrane Protein GPR1552 | | DEPDC31 2 | | |
Export aliases for GPR155 gene to outside databasesPrevious GC identifers: GC02M175500 GC02M175124 GC02M175004 GC02M167176 |
Summaries
for GPR155 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for GPR155
|
Genomic Views
for GPR155 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GPR155 gene promoter:
Olf-1 RelA NF-kappaB GATA-1 Evi-1 NF-AT2 FOXJ2 (long isoform) FOXJ2 NF-kappaB1 NF-AT1
Other transcription factors
Search SABiosciences Chromatin IP Primers for GPR155
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPR155 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q31.1 Ensembl cytogenetic band: 2q31.1 HGNC cytogenetic band: 2q31.1GPR155 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M175296: view genomic region
(about GC identifiers)
Start:
|
175,296,375 bp from pter |
End:
|
175,351,822 bp from pter |
Size:
|
55,448 bases |
Orientation:
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minus strand |
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Proteins
for GPR155 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GP155_HUMAN, Q7Z3F1 (See
protein sequence)Recommended Name: Integral membrane protein GPR155 Size: 870 amino acids; 96919 Da
Subcellular location: Membrane; Multi-pass membrane protein
Sequence caution: Sequence=BAB71170.1; Type=Erroneous initiation;
Secondary accessions: B2RCI2 D3DPE2 Q4G0Y6 Q53SJ3 Q53TA8 Q69YG8 Q86SP9 Q8N261 Q8N639 Q8N8K3 Q96MV6Explore the universe of human proteins at neXtProt for GPR155: NX_Q7Z3F1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q7Z3F1
GPR155 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001028217.1 NP_001253979.1 NP_001253980.1 NP_689742.4
ENSEMBL proteins: ENSP00000376335 ENSP00000376334 ENSP00000295500
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005622 | intracellular |
-- | -- | | GO:0016021 | integral to membrane |
IEA | -- |
GPR155 for ontologies About GeneDecksing
GPR155 Antibody Products:
Assay Products for GPR155: |
Protein
Domains /
Families
for GPR155 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GPR155 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q7Z3F1ProtoNet protein and cluster: Q7Z3F1 1 Blocks protein family: IPB004776 Auxin Efflux Carrier
UniProtKB/Swiss-Prot: GP155_HUMAN, Q7Z3F1Similarity: Contains 1 DEP domain |
Function
for GPR155 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GPR155 (NM_152529) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GPR155 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GPR155 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR155 |
|
Pathways & Interactions
for GPR155 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPR155
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0035556 | intracellular signal transduction |
IEA | -- | | GO:0055085 | transmembrane transport |
IEA | -- |
GPR155 for ontologies About GeneDecksing
|
Drugs & Compounds
for GPR155 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for GPR155
Search CenterWatch for drugs/clinical trials and news about GPR155 / GP155
|
Transcripts
for GPR155 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GPR155 gene (4 alternative transcripts): NM_001033045.3 NM_001267050.1 NM_001267051.1 NM_152529.6 Unigene Cluster for GPR155: G protein-coupled receptor 155 Hs.516604 [show with all ESTs]Unigene Representative Sequence: NM_0010330455 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000392552(uc002uit.3 uc002uiu.3 uc002uiv.3 uc010fqs.3)
ENST00000392551 ENST00000295500 ENST00000459996 ENST00000497620
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): GPR155 (NM_152529) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GPR155 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GPR155 |
Additional cDNA sequence: AK056381.1 AK091200.1 AK096665.1 AK307896.1 AK315125.1 AL834154.1 AY255528.1 BC028730.1 BC035037.1 BC036681.1 BX537947.1 6 DOTS entries: DT.91786639 DT.203881 DT.95284981 DT.95257905 DT.120968825 DT.91961448 24/69 AceView cDNA sequences (see all 69): AY255528 H89339 BF510153 BM894259 BF510155 CA419877 BQ581471 BM991366 AK091200 BM802275 AA939002 AK056381 BU074288 BQ478180 AW339878 AI733342 AX746845 AA934734 AI955141 BM698567 BE856826 BX537947 BC036681 CK301081
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for GPR155 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for GPR155
|
Expression
for GPR155 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GPR155 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACCCGGAAG
About this image
See GPR155 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GPR155
SOURCE GeneReport for Unigene cluster: Hs.516604
SABiosciences Custom PCR Arrays for GPR155
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GPR155
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GPR155 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GPR155 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GPR155 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR155 |
Orthologs
for GPR155 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for GPR155 gene from 6/19 species (see all 19) About this table
ENSEMBL Gene Tree for GPR155 (if available)
TreeFam Gene Tree for GPR155 (if available) |
Paralogs
for GPR155 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for GPR155 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for GPR155 (175296375 - 175351822 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GPR155: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GPR155 |
|
Disorders
/ Diseases
for GPR155 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 GPR155 for disorders About MalaCards
GPR155 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: GPR155 (1 document)
Export disorders for GPR155 gene to outside databases
|
Publications
for GPR155 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GPR155 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with GPR155) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The G protein-coupled receptor repertoires of human and mouse. (PubMed id 12679517)1, 2, 3 Vassilatis D.K.... Gaitanaris G.A. (2003)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for GPR155 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GPR155 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GPR155 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GPR155 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for GPR155 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GPR155 gene:
Search GeneIP for patents involving GPR155
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for GPR155 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for GPR155 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GPR155 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GPR155 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for GPR155 | | OriGene 3'-UTR Clone for GPR155 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GPR155 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |  |  |  |  | | | | |
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 | | | GPR155 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR155 |
|  |  |  | | | | ThermoFisher Antibodies for GPR155 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GPR155 |
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