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Aliases for GPR155 Gene

Aliases for GPR155 Gene

  • G Protein-Coupled Receptor 155 2 3 5
  • G-Protein Coupled Receptor PGR22 3 4
  • PGR22 3 4
  • Integral Membrane Protein GPR155 3
  • DEPDC3 3
  • DEP.7 3

External Ids for GPR155 Gene

Previous GeneCards Identifiers for GPR155 Gene

  • GC02M175500
  • GC02M175124
  • GC02M175004
  • GC02M175296
  • GC02M167176

Summaries for GPR155 Gene

GeneCards Summary for GPR155 Gene

GPR155 (G Protein-Coupled Receptor 155) is a Protein Coding gene.

Gene Wiki entry for GPR155 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR155 Gene

Genomics for GPR155 Gene

Regulatory Elements for GPR155 Gene

Enhancers for GPR155 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F174338 2.8 VISTA Ensembl ENCODE 8 +146.1 146070 5.0 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF48 SLC30A9 ELK1 ZNF143 FOS GPR155 GC02P174342 LOC102724194
GH02F174331 1.9 VISTA 8.1 +155.2 155244 1.1 RING1 ZNF362 SUZ12 RNF2 CBX2 ZFP69B SMARCA4 ZNF692 KDM1A MAFK GPR155 SP9 LINC01305
GH02F174585 1.7 FANTOM5 Ensembl ENCODE 6.4 -106.5 -106521 17.0 HDGF PKNOX1 MLX WRNIP1 ARID4B FEZF1 YY1 ZNF207 FOS MXD4 WIPF1 CIR1 GPR155 ENSG00000237798 GC02P174645
GH02F174492 1.3 FANTOM5 Ensembl ENCODE 8 -6.6 -6615 3.4 HDGF TBP MXI1 TBL1XR1 RBBP5 ZNF207 CREM MAZ MTA2 HLF WIPF1 GPR155 CIR1 GC02M174489 LOC442058
GH02F174394 1.1 ENCODE 8.4 +91.3 91326 2.7 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 SCRN3 GPR155
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPR155 on UCSC Golden Path with GeneCards custom track

Promoters for GPR155 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001549008 294 2800 ZFP64 SIN3A DMAP1 ZNF48 ZNF2 YY1 ZNF121 GLIS2 ELK1 ZNF263

Genomic Location for GPR155 Gene

Chromosome:
2
Start:
174,431,571 bp from pter
End:
174,487,094 bp from pter
Size:
55,524 bases
Orientation:
Minus strand

Genomic View for GPR155 Gene

Genes around GPR155 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPR155 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPR155 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR155 Gene

Proteins for GPR155 Gene

  • Protein details for GPR155 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3F1-GP155_HUMAN
    Recommended name:
    Integral membrane protein GPR155
    Protein Accession:
    Q7Z3F1
    Secondary Accessions:
    • B2RCI2
    • D3DPE2
    • Q4G0Y6
    • Q53SJ3
    • Q53TA8
    • Q69YG8
    • Q86SP9
    • Q8N261
    • Q8N639
    • Q8N8K3
    • Q96MV6

    Protein attributes for GPR155 Gene

    Size:
    870 amino acids
    Molecular mass:
    96919 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71170.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for GPR155 Gene

Post-translational modifications for GPR155 Gene

  • Glycosylation at Asn 9, Asn 15, Asn 29, Asn 198, Asn 309, Asn 381, Asn 543, and Asn 612
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPR155 Gene

Domains & Families for GPR155 Gene

Protein Domains for GPR155 Gene

Suggested Antigen Peptide Sequences for GPR155 Gene

Graphical View of Domain Structure for InterPro Entry

Q7Z3F1

UniProtKB/Swiss-Prot:

GP155_HUMAN :
  • Contains 1 DEP domain.
Domain:
  • Contains 1 DEP domain.
genes like me logo Genes that share domains with GPR155: view

No data available for Gene Families for GPR155 Gene

Function for GPR155 Gene

Gene Ontology (GO) - Molecular Function for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with GPR155: view
genes like me logo Genes that share phenotypes with GPR155: view

Animal Model Products

miRNA for GPR155 Gene

miRTarBase miRNAs that target GPR155

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPR155 Gene

Localization for GPR155 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR155 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPR155 gene
Compartment Confidence
extracellular 5
plasma membrane 3
cytosol 1

Gene Ontology (GO) - Cellular Components for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
GO:0005737 cytoplasm IBA --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome IDA 19056867
genes like me logo Genes that share ontologies with GPR155: view

Pathways & Interactions for GPR155 Gene

SuperPathways for GPR155 Gene

No Data Available

Interacting Proteins for GPR155 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000295500%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: Q7Z3F1-GP155_HUMAN ENSP00000295500 for GPR155 Gene via IID STRING

Gene Ontology (GO) - Biological Process for GPR155 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035556 intracellular signal transduction IEA --
GO:0050890 cognition IMP 17519220
GO:0055085 transmembrane transport IEA --
genes like me logo Genes that share ontologies with GPR155: view

No data available for Pathways by source and SIGNOR curated interactions for GPR155 Gene

Transcripts for GPR155 Gene

Unigene Clusters for GPR155 Gene

G protein-coupled receptor 155:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPR155 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
SP1:
SP2:
SP3: -
SP4: -
SP5: - -

Relevant External Links for GPR155 Gene

GeneLoc Exon Structure for
GPR155
ECgene alternative splicing isoforms for
GPR155

Expression for GPR155 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GPR155 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for GPR155 Gene

This gene is overexpressed in Urine (65.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GPR155 Gene



Protein tissue co-expression partners for GPR155 Gene

NURSA nuclear receptor signaling pathways regulating expression of GPR155 Gene:

GPR155

SOURCE GeneReport for Unigene cluster for GPR155 Gene:

Hs.516604
genes like me logo Genes that share expression patterns with GPR155: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPR155 Gene

Orthologs for GPR155 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPR155 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR155 34 35
  • 99.6 (n)
dog
(Canis familiaris)
Mammalia GPR155 34 35
  • 93.26 (n)
cow
(Bos Taurus)
Mammalia GPR155 34 35
  • 91.98 (n)
mouse
(Mus musculus)
Mammalia Gpr155 34 16 35
  • 85.68 (n)
rat
(Rattus norvegicus)
Mammalia Gpr155 34
  • 85.64 (n)
oppossum
(Monodelphis domestica)
Mammalia GPR155 35
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPR155 35
  • 82 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPR155 34 35
  • 74.96 (n)
lizard
(Anolis carolinensis)
Reptilia GPR155 35
  • 70 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr155 34
  • 68.28 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.19272 34
zebrafish
(Danio rerio)
Actinopterygii gpr155a 34 35
  • 60.06 (n)
gpr155b 35
  • 56 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7510 34 35
  • 46.19 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP006992 34
  • 45.63 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 40 (a)
OneToOne
Species where no ortholog for GPR155 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR155 Gene

ENSEMBL:
Gene Tree for GPR155 (if available)
TreeFam:
Gene Tree for GPR155 (if available)

Paralogs for GPR155 Gene

No data available for Paralogs for GPR155 Gene

Variants for GPR155 Gene

Sequence variations from dbSNP and Humsavar for GPR155 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10168192 -- 174,445,301(+) AAACA(C/G)TGAGA intron-variant
rs10168277 -- 174,475,350(+) ACTAA(A/G)ATAAA intron-variant
rs10179192 -- 174,458,948(+) CCAGG(C/T)GTGGT intron-variant
rs10183260 -- 174,460,721(+) CACTT(C/T)CACGT intron-variant
rs10192906 -- 174,433,006(+) gatcc(A/G)ccagc utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for GPR155 Gene

Variant ID Type Subtype PubMed ID
esv3893507 CNV loss 25118596
nsv526187 CNV loss 19592680
nsv583667 CNV loss 21841781

Variation tolerance for GPR155 Gene

Residual Variation Intolerance Score: 7.31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.04; 37.54% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPR155 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPR155

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR155 Gene

Disorders for GPR155 Gene

Relevant External Links for GPR155

Genetic Association Database (GAD)
GPR155
Human Genome Epidemiology (HuGE) Navigator
GPR155
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPR155

No disorders were found for GPR155 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR155 Gene

Publications for GPR155 Gene

  1. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4 64
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 64
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for GPR155 Gene

Sources for GPR155 Gene

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