Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GPR152 Gene

Aliases for GPR152 Gene

  • G Protein-Coupled Receptor 152 2 3
  • PGR5 3 4
  • G Protein-Coupled Receptor PGR5 3
  • G-Protein Coupled Receptor PGR5 4

External Ids for GPR152 Gene

Previous GeneCards Identifiers for GPR152 Gene

  • GC00U914420
  • GC11M066995
  • GC11M066975
  • GC11M067218
  • GC11M063548

Summaries for GPR152 Gene

GeneCards Summary for GPR152 Gene

GPR152 (G Protein-Coupled Receptor 152) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is FPR2.

UniProtKB/Swiss-Prot for GPR152 Gene

  • Orphan receptor

Gene Wiki entry for GPR152 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR152 Gene

Genomics for GPR152 Gene

Regulatory Elements for GPR152 Gene

Genomic Location for GPR152 Gene

Chromosome:
11
Start:
67,451,301 bp from pter
End:
67,452,729 bp from pter
Size:
1,429 bases
Orientation:
Minus strand

Genomic View for GPR152 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GPR152 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR152 Gene

Proteins for GPR152 Gene

  • Protein details for GPR152 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TDT2-GP152_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 152
    Protein Accession:
    Q8TDT2
    Secondary Accessions:
    • Q0VD88
    • Q86SM0

    Protein attributes for GPR152 Gene

    Size:
    470 amino acids
    Molecular mass:
    50962 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPR152 Gene

Proteomics data for GPR152 Gene at MOPED

Post-translational modifications for GPR152 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GPR152 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for GPR152 Gene

Domains & Families for GPR152 Gene

Gene Families for GPR152 Gene

Protein Domains for GPR152 Gene

Suggested Antigen Peptide Sequences for GPR152 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TDT2

UniProtKB/Swiss-Prot:

GP152_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with GPR152: view

Function for GPR152 Gene

Molecular function for GPR152 Gene

UniProtKB/Swiss-Prot Function:
Orphan receptor

Gene Ontology (GO) - Molecular Function for GPR152 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
genes like me logo Genes that share ontologies with GPR152: view
genes like me logo Genes that share phenotypes with GPR152: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPR152

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GPR152 Gene

Localization for GPR152 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR152 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GPR152 Gene COMPARTMENTS Subcellular localization image for GPR152 gene
Compartment Confidence
plasma membrane 5
chloroplast 2

Gene Ontology (GO) - Cellular Components for GPR152 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with GPR152: view

Pathways & Interactions for GPR152 Gene

SuperPathways for GPR152 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays
    • G Protein Coupled Receptors 384HT in human,mouse,rat

Interacting Proteins for GPR152 Gene

Gene Ontology (GO) - Biological Process for GPR152 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with GPR152: view

No data available for Pathways by source and SIGNOR curated interactions for GPR152 Gene

Drugs & Compounds for GPR152 Gene

No Compound Related Data Available

Transcripts for GPR152 Gene

mRNA/cDNA for GPR152 Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPR152

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPR152 Gene

No ASD Table

Relevant External Links for GPR152 Gene

GeneLoc Exon Structure for
GPR152
ECgene alternative splicing isoforms for
GPR152

Expression for GPR152 Gene

mRNA expression in normal human tissues for GPR152 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for GPR152 Gene Hs.567997

genes like me logo Genes that share expression patterns with GPR152: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GPR152 Gene

Orthologs for GPR152 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPR152 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GPR152 35
  • 85.43 (n)
  • 80.57 (a)
GPR152 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPR152 35
  • 84.05 (n)
  • 80.56 (a)
GPR152 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpr152 35
  • 78.79 (n)
  • 78.72 (a)
Gpr152 16
Gpr152 36
  • 72 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GPR152 35
  • 99.15 (n)
  • 99.36 (a)
rat
(Rattus norvegicus)
Mammalia Gpr152 35
  • 78.58 (n)
  • 77.45 (a)
oppossum
(Monodelphis domestica)
Mammalia GPR152 36
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 19 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii CU571081.1 36
  • 18 (a)
OneToOne
Species with no ortholog for GPR152:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR152 Gene

ENSEMBL:
Gene Tree for GPR152 (if available)
TreeFam:
Gene Tree for GPR152 (if available)

Paralogs for GPR152 Gene

genes like me logo Genes that share paralogs with GPR152: view

Variants for GPR152 Gene

Sequence variations from dbSNP and Humsavar for GPR152 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
VAR_059323 -

Structural Variations from Database of Genomic Variants (DGV) for GPR152 Gene

Variant ID Type Subtype PubMed ID
nsv897797 CNV Loss 21882294
nsv897801 CNV Loss 21882294
nsv897804 CNV Gain 21882294
dgv1193n71 CNV Loss 21882294
dgv1194n71 CNV Loss 21882294
nsv897811 CNV Loss 21882294
nsv521723 CNV Loss 19592680
nsv524096 CNV Loss 19592680
nsv468604 CNV Loss 19166990
nsv527056 CNV Loss 19592680

Variation tolerance for GPR152 Gene

Residual Variation Intolerance Score: 47.73% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.30; 62.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPR152 Gene

HapMap Linkage Disequilibrium report
GPR152
Human Gene Mutation Database (HGMD)
GPR152

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPR152 Gene

Disorders for GPR152 Gene

Relevant External Links for GPR152

Genetic Association Database (GAD)
GPR152
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPR152
genes like me logo Genes that share disorders with GPR152: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR152 Gene

Publications for GPR152 Gene

  1. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 67
  2. Nine new human Rhodopsin family G-protein coupled receptors: identification, sequence characterisation and evolutionary relationship. (PMID: 15777626) Gloriam D.E. … Fredriksson R. (Biochim. Biophys. Acta 2005) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for GPR152 Gene

  • Pathway & Disease-focused RT² Profiler PCR Arrays
    • G Protein Coupled Receptors 384HT in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate GPR152
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for GPR152
    • Block miRNA regulation of GPR152 using miScript Target Protectors

    Sources for GPR152 Gene

    Back to Top

    Content