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Aliases for GPR151 Gene

Aliases for GPR151 Gene

  • G Protein-Coupled Receptor 151 2 3
  • G-Protein Coupled Receptor PGR7 3 4
  • Galanin Receptor 4 2 3
  • GPCR-2037 3 4
  • PGR7 3 4
  • Putative G-Protein Coupled Receptor 3
  • GALR4 3
  • GALRL 3
  • GPCR 3

External Ids for GPR151 Gene

Previous GeneCards Identifiers for GPR151 Gene

  • GC05M145922
  • GC05M145874
  • GC05M141041

Summaries for GPR151 Gene

GeneCards Summary for GPR151 Gene

GPR151 (G Protein-Coupled Receptor 151) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity.

UniProtKB/Swiss-Prot for GPR151 Gene

  • Orphan receptor

Gene Wiki entry for GPR151 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR151 Gene

Genomics for GPR151 Gene

Regulatory Elements for GPR151 Gene

Genomic Location for GPR151 Gene

Chromosome:
5
Start:
146,513,103 bp from pter
End:
146,516,190 bp from pter
Size:
3,088 bases
Orientation:
Minus strand

Genomic View for GPR151 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for GPR151 Gene

Proteins for GPR151 Gene

  • Protein details for GPR151 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TDV0-GP151_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 151
    Protein Accession:
    Q8TDV0
    Secondary Accessions:
    • Q86SN8
    • Q8NGV2

    Protein attributes for GPR151 Gene

    Size:
    419 amino acids
    Molecular mass:
    46637 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05899.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for GPR151 Gene

Proteomics data for GPR151 Gene at MOPED

Post-translational modifications for GPR151 Gene

  • Glycosylation at Asn 10 and Asn 15
  • Modification sites at PhosphoSitePlus

Other Protein References for GPR151 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for GPR151 Gene

Domains & Families for GPR151 Gene

Gene Families for GPR151 Gene

Protein Domains for GPR151 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPR151 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TDV0

UniProtKB/Swiss-Prot:

GP151_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with GPR151: view

Function for GPR151 Gene

Molecular function for GPR151 Gene

UniProtKB/Swiss-Prot Function:
Orphan receptor

Gene Ontology (GO) - Molecular Function for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
genes like me logo Genes that share ontologies with GPR151: view

Phenotypes for GPR151 Gene

genes like me logo Genes that share phenotypes with GPR151: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPR151

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for GPR151 Gene

Localization for GPR151 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR151 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GPR151 Gene COMPARTMENTS Subcellular localization image for GPR151 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with GPR151: view

Pathways & Interactions for GPR151 Gene

SuperPathways for GPR151 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway --
GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with GPR151: view

No data available for Pathways by source and SIGNOR curated interactions for GPR151 Gene

Drugs & Compounds for GPR151 Gene

(1) Drugs for GPR151 Gene - From: NovoSeek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dopamine Approved Pharma Full agonist, Agonist 2814
genes like me logo Genes that share compounds with GPR151: view

Transcripts for GPR151 Gene

mRNA/cDNA for GPR151 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GPR151 Gene

G protein-coupled receptor 151:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPR151

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPR151 Gene

No ASD Table

Relevant External Links for GPR151 Gene

GeneLoc Exon Structure for
GPR151
ECgene alternative splicing isoforms for
GPR151

Expression for GPR151 Gene

mRNA expression in normal human tissues for GPR151 Gene

mRNA differential expression in normal tissues according to GTEx for GPR151 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x7.7), Brain - Anterior cingulate cortex (BA24) (x6.4), Brain - Frontal Cortex (BA9) (x6.2), Brain - Cortex (x4.6), and Brain - Substantia nigra (x4.5).

SOURCE GeneReport for Unigene cluster for GPR151 Gene Hs.483732

genes like me logo Genes that share expression patterns with GPR151: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GPR151 Gene

Orthologs for GPR151 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPR151 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GPR151 35
  • 88.59 (n)
  • 85.96 (a)
GPR151 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPR151 35
  • 86.99 (n)
  • 83.9 (a)
GPR151 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpr151 35
  • 82.69 (n)
  • 78.26 (a)
Gpr151 16
Gpr151 36
  • 77 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GPR151 35
  • 99.52 (n)
  • 99.28 (a)
GPR151 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpr151 35
  • 83.45 (n)
  • 79.32 (a)
oppossum
(Monodelphis domestica)
Mammalia GPR151 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPR151 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GPR151 36
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr151 35
  • 60.54 (n)
  • 52.7 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100538082 35
  • 54.44 (n)
  • 44.99 (a)
GPR151 36
  • 28 (a)
OneToOne
Species with no ortholog for GPR151:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR151 Gene

ENSEMBL:
Gene Tree for GPR151 (if available)
TreeFam:
Gene Tree for GPR151 (if available)

Paralogs for GPR151 Gene

No data available for Paralogs for GPR151 Gene

Variants for GPR151 Gene

Sequence variations from dbSNP and Humsavar for GPR151 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
VAR_049405 -
VAR_049406 -
VAR_049404 -

Variation tolerance for GPR151 Gene

Residual Variation Intolerance Score: 96.04% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.28; 70.36% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPR151 Gene

HapMap Linkage Disequilibrium report
GPR151

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPR151 Gene

Disorders for GPR151 Gene

Relevant External Links for GPR151

Genetic Association Database (GAD)
GPR151
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPR151
genes like me logo Genes that share disorders with GPR151: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPR151 Gene

Publications for GPR151 Gene

  1. Activation of calcitonin receptor and calcitonin receptor-like receptor by membrane-anchored ligands. (PMID: 19903822) Chang C.L. … Hsu S.Y. (J. Biol. Chem. 2010) 23 67
  2. Structure-function relationships of the N-terminus of receptor activity-modifying proteins. (PMID: 20015292) Qi T. … Hay D.L. (Br. J. Pharmacol. 2010) 23 67
  3. Functional characterization of two human receptor activity-modifying protein 3 variants. (PMID: 20034525) Bailey R.J. … Hay D.L. (Peptides 2010) 23 67
  4. Patterns of divergence in the vCXCL and vGPCR gene clusters in primate cytomegalovirus genomes. (PMID: 19818982) Alcendor D.J. … Hayward G.S. (Virology 2009) 23 67
  5. Suppression of CCL2/MCP-1 and CCL5/RANTES expression by nociceptin in human monocytes. (PMID: 18247127) Kaminsky D.E. … Rogers T.J. (J Neuroimmune Pharmacol 2008) 23 67

Products for GPR151 Gene

Sources for GPR151 Gene

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