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Aliases for GPR151 Gene

Aliases for GPR151 Gene

  • G Protein-Coupled Receptor 151 2 3
  • G-Protein Coupled Receptor PGR7 3 4
  • Galanin Receptor 4 2 3
  • GPCR-2037 3 4
  • PGR7 3 4
  • Probable G-Protein Coupled Receptor 151 3
  • Putative G-Protein Coupled Receptor 3
  • GALR4 3
  • GALRL 3
  • GPCR 3

External Ids for GPR151 Gene

Previous GeneCards Identifiers for GPR151 Gene

  • GC05M145922
  • GC05M145874
  • GC05M141041

Summaries for GPR151 Gene

GeneCards Summary for GPR151 Gene

GPR151 (G Protein-Coupled Receptor 151) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity.

UniProtKB/Swiss-Prot for GPR151 Gene

  • Orphan receptor

Gene Wiki entry for GPR151 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPR151 Gene

Genomics for GPR151 Gene

Regulatory Elements for GPR151 Gene

Genomic Location for GPR151 Gene

Start:
146,513,103 bp from pter
End:
146,516,190 bp from pter
Size:
3,088 bases
Orientation:
Minus strand

Genomic View for GPR151 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GPR151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPR151 Gene

Proteins for GPR151 Gene

  • Protein details for GPR151 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TDV0-GP151_HUMAN
    Recommended name:
    Probable G-protein coupled receptor 151
    Protein Accession:
    Q8TDV0
    Secondary Accessions:
    • Q86SN8
    • Q8NGV2

    Protein attributes for GPR151 Gene

    Size:
    419 amino acids
    Molecular mass:
    46637 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05899.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for GPR151 Gene

Proteomics data for GPR151 Gene at MOPED

Post-translational modifications for GPR151 Gene

  • Glycosylation at Asn10 and Asn15
  • Modification sites at PhosphoSitePlus

Other Protein References for GPR151 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GPR151 Gene

Domains for GPR151 Gene

Gene Families for GPR151 Gene

HGNC:
  • GPCRAO :GPCR / Class A : Orphans
IUPHAR :

Protein Domains for GPR151 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPR151 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TDV0

UniProtKB/Swiss-Prot:

GP151_HUMAN :
  • Q8TDV0
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with GPR151: view

Function for GPR151 Gene

Molecular function for GPR151 Gene

UniProtKB/Swiss-Prot Function: Orphan receptor

Gene Ontology (GO) - Molecular Function for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
genes like me logo Genes that share ontologies with GPR151: view

Phenotypes for GPR151 Gene

MGI mutant phenotypes for GPR151:
inferred from 1 alleles
GenomeRNAi human phenotypes for GPR151:
genes like me logo Genes that share phenotypes with GPR151: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for GPR151 Gene

Localization for GPR151 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPR151 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GPR151 Gene COMPARTMENTS Subcellular localization image for GPR151 gene
Compartment Confidence
plasma membrane 5
chloroplast 2

Gene Ontology (GO) - Cellular Components for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GPR151: view

Pathways for GPR151 Gene

SuperPathways for GPR151 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPR151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with GPR151: view

No data available for Pathways by source for GPR151 Gene

Compounds for GPR151 Gene

(1) Novoseek inferred chemical compound relationships for GPR151 Gene

Compound -log(P) Hits PubMed IDs
dopamine 0 1
genes like me logo Genes that share compounds with GPR151: view

Transcripts for GPR151 Gene

mRNA/cDNA for GPR151 Gene

(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GPR151 Gene

G protein-coupled receptor 151:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPR151 Gene

No ASD Table

Relevant External Links for GPR151 Gene

GeneLoc Exon Structure for
GPR151
ECgene alternative splicing isoforms for
GPR151

Expression for GPR151 Gene

mRNA expression in normal human tissues for GPR151 Gene

mRNA differential expression in normal tissues according to GTEx for GPR151 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (7.7), Brain - Anterior cingulate cortex (BA24) (6.4), Brain - Frontal Cortex (BA9) (6.2), Brain - Cortex (4.6), and Brain - Substantia nigra (4.5).

SOURCE GeneReport for Unigene cluster for GPR151 Gene Hs.483732

genes like me logo Genes that share expressions with GPR151: view

No data available for Protein expression and mRNA Expression by UniProt/SwissProt for GPR151 Gene

Orthologs for GPR151 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPR151 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPR151 35
  • 99.52 (n)
  • 99.28 (a)
GPR151 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GPR151 35
  • 88.59 (n)
  • 85.96 (a)
GPR151 36
  • 84 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPR151 35
  • 86.99 (n)
  • 83.9 (a)
GPR151 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpr151 35
  • 82.69 (n)
  • 78.26 (a)
Gpr151 16
Gpr151 36
  • 77 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPR151 36
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPR151 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpr151 35
  • 83.45 (n)
  • 79.32 (a)
lizard
(Anolis carolinensis)
Reptilia GPR151 36
  • 59 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpr151 35
  • 60.54 (n)
  • 52.7 (a)
zebrafish
(Danio rerio)
Actinopterygii GPR151 36
  • 28 (a)
OneToOne
LOC100538082 35
  • 54.44 (n)
  • 44.99 (a)
Species with no ortholog for GPR151:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPR151 Gene

ENSEMBL:
Gene Tree for GPR151 (if available)
TreeFam:
Gene Tree for GPR151 (if available)

Paralogs for GPR151 Gene

No data available for Paralogs for GPR151 Gene

Variants for GPR151 Gene

Sequence variations from dbSNP and Humsavar for GPR151 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs6894849 -- 146,517,588(+) GAAAA(C/G)CTAAA upstream-variant-2KB
rs7709485 - 146,515,333(+) CAAGA(C/G)AGCAG reference, missense
rs7713676 - 146,515,683(+) GCTTG(A/G)CTGGG reference, missense
rs9325013 -- 146,516,583(+) TGGCC(C/G)GATCC upstream-variant-2KB
rs10062873 -- 146,516,774(+) GTTCC(A/C)TCAAC upstream-variant-2KB

Relevant External Links for GPR151 Gene

HapMap Linkage Disequilibrium report
GPR151

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPR151 Gene

Disorders for GPR151 Gene

Relevant External Links for GPR151

Genetic Association Database (GAD)
GPR151
genes like me logo Genes that share disorders with GPR151: view

No data available for UniProtKB/Swiss-Prot for GPR151 Gene

Publications for GPR151 Gene

  1. The G protein-coupled receptor repertoires of human and mouse. (PMID: 12679517) Vassilatis D.K. … Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3 4
  2. Identification of G protein-coupled receptor genes from the human genome sequence. (PMID: 12044878) Takeda S. … Mitaku S. (FEBS Lett. 2002) 3 4
  3. Cloning and characterization of a novel G-protein-coupled receptor with homology to galanin receptors. (PMID: 15111018) Ignatov A. … Schaller H.C. (Neuropharmacology 2004) 3
  4. Hydrophobic amino acid in the i2 loop plays a key role in receptor-G protein coupling. (PMID: 8226735) Moro O. … SadAce W. (J. Biol. Chem. 1993) 23
  5. STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV- 1. (PMID: 9166430) Liao F. … Farber J.M. (J. Exp. Med. 1997) 23

Products for GPR151 Gene

  • antibodies-online proteins for GPR151
  • antibodies-online antibodies for GPR151
  • antibodies-online kits for GPR151

Sources for GPR151 Gene

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