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Aliases &
Descriptions
for GPR142
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| | | Descriptions |
|---|
| G protein-coupled receptor 142 2 | | G-protein coupled receptor PGR2 3 |
|
| |
Search outside databases for aliases for GPR142 genePrevious GC identifers: GC17P072829 GC17P072919 |
Summaries
for GPR142(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for GPR142:
GPR142 is a member of the rhodopsin family of G protein-coupled receptors (GPRs) (Fredriksson et
al., 2003 [PubMed 14623098]).[supplied by OMIM]
UniProtKB/Swiss-Prot: GP142_HUMAN, Q7Z601Function: Orphan receptorGene Wiki entry for GPR142 |
Genomic Location
for GPR142
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the GPR142 gene 
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.2GPR142 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P069875:
(about GC identifiers)
Start:
|
69,875,240 bp from pter |
End:
|
69,880,334 bp from pter |
Size:
|
5,095 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000017.9 NT_010641.15
| Proteins
for GPR142
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: GP142_HUMAN, Q7Z601 (See
protein sequence)Recommended Name: Probable G-protein coupled receptor 142 Size: 462 amino acids; 51106 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: A4CYJ8 Q86SL3REFSEQ proteins: NP_861455.1
ENSEMBL proteins: ENSP00000335158
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
2 Gene Ontology (GO) cellular component terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005886 | plasma membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- |
About this table
Antibodies for GPR142:
Assays for GPR142: | Protein
Domains/
Families
for GPR142(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q7Z601
ProtoNet protein and cluster: Q7Z601 UniProtKB/Swiss-Prot: GP142_HUMAN, Q7Z601Similarity: Belongs to the G-protein coupled receptor 1 family | Gene Function
for GPR142
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181790
 Applied Biosystems Silencer® siRNAs for GPR142
 Sigma-Aldrich siRNA and siRNA Panels for GPR142
Sigma-Aldrich shRNA for GPR142
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_181790
Myc/DDK tagged cDNA clone in CMV expression vector: NM_181790
untagged cDNA clones in CMV expression vector (see all 2): NM_181790
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_181790
UniProtKB/Swiss-Prot: GP142_HUMAN, Q7Z601Function: Orphan receptor1 MGI phenotypic allele  for Gpr142 (no phenotypes)
2 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004872 | receptor activity |
IEA | -- | | GO:0004930 | G-protein coupled receptor activity |
IEA | -- |
About this table | Pathways & Interactions
for GPR142
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--2 Gene Ontology (GO) biological process terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007165 | signal transduction |
IEA | -- | | GO:0007186 | G-protein coupled receptor protein signaling pathway |
IEA | -- |
About this table
|
Drugs & Compounds
for GPR142(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for GPR142
|
Transcripts
for GPR142(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_181790
Sigma-Aldrich siRNA and siRNA Panels for GPR142
Sigma-Aldrich shRNA for GPR142
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_181790 REFSEQ mRNAs for GPR142 gene: NM_181790.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_181790
OriGene GFP tagged cDNA clone in CMV expression vector: NM_181790
Myc/DDK tagged cDNA clone in CMV expression vector: NM_181790
untagged cDNA clones in CMV expression vector (see all 2): NM_181790
Additional cDNA sequence: AB196530.1 AY255622.1 AY288421.1 BC143807.1 1 DOTS entry: DT.100735857 3 AceView cDNA sequences:AY288421 NM_181790 AY255622
 highest scoring ESTs for GPR142:AY255622 AY288421 AB196530 NM_181790 DY312809 DY312859 AI458534 Unigene Cluster for GPR142: G protein-coupled receptor 142 Hs.574368 [show with all ESTs]Unigene Representative Sequence: BC143807
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000335666
|
Expression
for GPR142
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| GPR142 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for GPR142
1 Data from GNF BioGPS
About these images
About these images
CGAP SAGE TAG: GCGGCGAAGC
SOURCE GeneReport for Unigene cluster: Hs.574368
UniProtKB/Swiss-Prot: GP142_HUMAN, Q7Z601Tissue specificity: Exclusively expressed in the central nervous system, most abundantly in the
ventrolateral region of caudate putamen, the habenular nucleus, the zona incerta, and the medial
mammillary nucleus |
Orthologs
for GPR142
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for GPR142 gene from 5/7 species (see all 7
)
About this table Species with no ortholog for GPR142
ENSEMBL Gene Tree for GPR142 | Paralogs
for GPR142(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for GPR142 gene
- GPR1392
|
SNPs/Variants
for GPR142(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for GPR142 (up to first 250kb)
|
Disorders & Mutations
for GPR142
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 609046
|
Medical News
for GPR142(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for GPR142 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for GPR142 gene: |
Search for GPR142
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GPR142
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing GPR142
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GPR142(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for GPR142(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for GPR142:
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