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GPR112 Gene

protein-coding   GIFtS: 47
GCID: GC0XP135383

G Protein-Coupled Receptor 112

  See GPR112-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
G Protein-Coupled Receptor 1121 2
PGR172
RP1-299I162
Probable G-Protein Coupled Receptor 1122

External Ids:    HGNC: 189921   Entrez Gene: 1393782   Ensembl: ENSG000001569207   UniProtKB: Q8IZF63   

Export aliases for GPR112 gene to outside databases

Previous GC identifers: GC0XP132250 GC0XP133349 GC0XP134110 GC0XP135130 GC0XP135210 GC0XP124653


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GPR112 Gene:
This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins
that participate in various physiological functions. Members of this superfamily are characterized by a signature
7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan
receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal
neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for
immunotherapy. (provided by RefSeq, May 2010)

GeneCards Summary for GPR112 Gene:
GPR112 (G protein-coupled receptor 112) is a protein-coding gene. Diseases associated with GPR112 include neuroendocrine carcinoma. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is GPR97.

UniProtKB/Swiss-Prot: GP112_HUMAN, Q8IZF6
Function: Orphan receptor

Gene Wiki entry for GPR112 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011786.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GPR112 gene promoter:
         Max1   AP-1   Nkx2-2   Olf-1   FOXD1   CUTL1   GATA-1   S8   Nkx6-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGPR112 promoter sequence
   Search Chromatin IP Primers for GPR112

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GPR112


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq26.3   Ensembl cytogenetic band:  Xq26.3   HGNC cytogenetic band: Xq26.3

GPR112 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GPR112 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP135383:  view genomic region     (about GC identifiers)

Start:
135,383,122 bp from pter      End:
135,519,215 bp from pter
Size:
136,094 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GP112_HUMAN, Q8IZF6 (See protein sequence)
Recommended Name: Probable G-protein coupled receptor 112 precursor  
Size: 3080 amino acids; 333368 Da
Secondary accessions: A2A2J1 A2A2J2 Q5EGP2 Q86SM6
Alternative splicing: 3 isoforms:  Q8IZF6-1   Q8IZF6-2   Q8IZF6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GPR112: NX_Q8IZF6

Explore proteomics data for GPR112 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn233, Asn487, Asn836, Asn899, Asn1020, Asn1519, Asn2361, Asn2640
  • Modification sites at PhosphoSitePlus

  • See GPR112 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_722576.3  
    ENSEMBL proteins: 
     ENSP00000377699   ENSP00000377697   ENSP00000359686   ENSP00000416526   ENSP00000287534  

    GPR112 Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GPR112

     
    Search eBioscience for Proteins for GPR112 

     
    Search antibodies-online for proteins for GPR112 

     
    Search antibodies-online for peptides for GPR112

    GPR112 Antibody Products:

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    antibodies-online antibodies for GPR112 

    GPR112 Assay Products:

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    Cloud-Clone Corp. CLIAs for GPR112
    Search eBioscience for ELISAs for GPR112 
    antibodies-online kits for GPR112 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPCRBO: GPCR / Class B : Orphans

    IUPHAR Guide to PHARMACOLOGY protein family classification: GPR112
    Adhesion Class GPCRs

    Selected InterPro protein domains (see all 7):
     IPR013320 ConA-like_subgrp
     IPR001759 Pentaxin
     IPR000832 GPCR_2_secretin-like
     IPR017983 GPCR_2_secretin-like_CS
     IPR017981 GPCR_2-like

    Graphical View of Domain Structure for InterPro Entry Q8IZF6

    ProtoNet protein and cluster: Q8IZF6

    1 Blocks protein domain: IPB000203 GPS domain

    UniProtKB/Swiss-Prot: GP112_HUMAN, Q8IZF6
    Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily
    Similarity: Contains 1 GPS domain


    Find genes that share domains with GPR112           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GP112_HUMAN, Q8IZF6
    Function: Orphan receptor

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004888transmembrane signaling receptor activity ----
    GO:0004930G-protein coupled receptor activity IEA--
         
    Find genes that share ontologies with GPR112           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for GPR112:
     Elongated cells with protrusio 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for GPR112

    miRNA
    Products:
        
    miRTarBase miRNAs that target GPR112:
    hsa-mir-335-5p (MIRT018820)

    Block miRNA regulation of human, mouse, rat GPR112 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GPR112 (see all 9):
    hsa-miR-3679-3p hsa-miR-4272 hsa-miR-944 hsa-miR-1257 hsa-miR-3692 hsa-miR-513b hsa-miR-889 hsa-miR-758
    SwitchGear 3'UTR luciferase reporter plasmidGPR112 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for GPR112
    Predesigned siRNA for gene silencing in human, mouse, rat GPR112

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: GPR112 (NM_153834)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GPR112
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GPR112

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR112


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GP112_HUMAN, Q8IZF6: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with GPR112           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including GPR112: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for GPR112

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007166cell surface receptor signaling pathway ----
    GO:0007186G-protein coupled receptor signaling pathway TAS15203201
    GO:0007218neuropeptide signaling pathway IEA--

    Find genes that share ontologies with GPR112           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GPR112 (GP112)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GPR112 gene: 
    NM_153834.3  

    Unigene Cluster for GPR112:

    G protein-coupled receptor 112
    Hs.381354
    Unigene Representative Sequence: AY882585
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000394143(uc004ezu.1) ENST00000394141 ENST00000370652 ENST00000412101(uc010nsb.1)
    ENST00000287534(uc010nsc.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GPR112 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GPR112 (see all 9):
    hsa-miR-3679-3p hsa-miR-4272 hsa-miR-944 hsa-miR-1257 hsa-miR-3692 hsa-miR-513b hsa-miR-889 hsa-miR-758
    SwitchGear 3'UTR luciferase reporter plasmidGPR112 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for GPR112
    Predesigned siRNA for gene silencing in human, mouse, rat GPR112
    Clone
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    OriGene clones in human, mouse for GPR112 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GPR112 (NM_153834)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GPR112
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat GPR112
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for GPR112
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GPR112
      QuantiTect SYBR Green Assays in human, mouse, rat GPR112
      QuantiFast Probe-based Assays in human, mouse, rat GPR112

    Additional mRNA sequence: 

    AY140954.1 AY255581.1 AY882585.1 CR936801.1 

    1 DOTS entry:

    DT.121297413 

    3 AceView cDNA sequences:

    AY255581 NM_153834 AY140954 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GPR112 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    GPR112 Expression
    About this image

    GPR112 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GPR112 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.381354

    UniProtKB/Swiss-Prot: GP112_HUMAN, Q8IZF6
    Tissue specificity: Detected in fetal retina. Highly expressed in normal enterochromaffin cells and in
    neuroendocrine carcinoma. Detected in normal liver; highly expressed in primary liver carcinoma

        Pathway & Disease-focused RT2 Profiler PCR Array including GPR112: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GPR112
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GPR112
    QuantiTect SYBR Green Assays in human, mouse, rat GPR112
    QuantiFast Probe-based Assays in human, mouse, rat GPR112
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPR112

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for GPR112 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gpr1121 , 5 G protein-coupled receptor 1121, 5 75.22(n)1
    60.38(a)1
      X (30.34 cM)5
    2367981  XM_003085259.21  XP_003085307.11 
     568701635 
    chicken
    (Gallus gallus)
    Aves GPR1121 G protein-coupled receptor 112 57.02(n)
    46.5(a)
      422244  XM_004940677.1  XP_004940734.1 
    lizard
    (Anolis carolinensis)
    Reptilia GPR1126
    G protein-coupled receptor 112
    54(a)
    1 ↔ 1
    GL343562.1(101446-125149)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7939631 probable G-protein coupled receptor 112-like 51.27(n)
    41.3(a)
      793963  XM_001333809.3  XP_001333845.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cirl6
    Cirl
    9(a)
    1 → many
    2R(4502227-4512708)
    worm
    (Caenorhabditis elegans)
    Secernentea lat-26
    Protein LAT-2, isoform a
    12(a)
    1 → many
    II(4359082-4368281) WBGene00002252


    ENSEMBL Gene Tree for GPR112 (if available)
    TreeFam Gene Tree for GPR112 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GPR112 gene
    GPR972  CD972  ELTD12  LPHN22  LPHN12  GPR1142  EMR12  LPHN32  
    EMR22  GPR1332  GPR1442  EMR32  GPR562  GPR1262  GPR642  
    5 SIMAP similar genes for GPR112 using alignment to 1 protein entry:     GP112_HUMAN:
    GPR64    FLJ00046    FLJ00015    GPR114    ELTD1

    Find genes that share paralogs with GPR112           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GPR112 (see all 1728)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822207891,2
    --135339126(+) AGCCAC/TCCCAT 1 -- us2k10--------
    rs66352591,2
    C--135339251(+) catcaA/Ctgata 1 -- us2k11Minor allele frequency- C:0.00NA 2
    rs123827841,2
    C--135339494(+) ggggtC/Gggggg 1 -- us2k1 tfbs30--------
    rs1859512741,2
    --135339495(+) GGGTGC/GGGGGA 1 -- us2k10--------
    rs1915917821,2
    --135339641(+) AATAAC/TAAAAA 1 -- us2k10--------
    rs1996292791,2
    --135339695(+) ATGGT-/TATATAT 1 -- us2k10--------
    rs1829249351,2
    --135339709(+) TATATA/TTTAGG 1 -- us2k10--------
    rs1887758871,2
    --135339716(+) TAGGGC/GTCTTC 1 -- us2k10--------
    rs1922501201,2
    C--135339906(+) AAGACA/CGGTTT 1 -- us2k10--------
    rs2008160051,2
    --135339907(+) AGACA-/GGTTTA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GPR112 (135383122 - 135519215 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for GPR112: --
    Human Gene Mutation Database (HGMD): GPR112
    Locus Specific Mutation Databases (LSDB): GPR112

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GPR112
    DNA2.0 Custom Variant and Variant Library Synthesis for GPR112

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for GPR112:    
    About MalaCards
    neuroendocrine carcinoma

    1 disease from the University of Copenhagen DISEASES database for GPR112:
    Neuroendocrine carcinoma

    Find genes that share disorders with GPR112           About GenesLikeMe


    Export disorders for GPR112 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GPR112 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with GPR112)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions. (PubMed id 12435584)1, 2, 3 Fredriksson R.... Schioeth H.B. (FEBS Lett. 2002)
    2. Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. (PubMed id 18953328)1, 2, 9 Leja J....Giandomenico V. (Mod. Pathol. 2009)
    3. The G protein-coupled receptor repertoires of human and mouse. (PubMed id 12679517)1, 2 Vassilatis D.K.... Gaitanaris G.A. (Proc. Natl. Acad. Sci. U.S.A. 2003)
    4. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    5. The human and mouse repertoire of the adhesion family of G-protein- coupled receptors. (PubMed id 15203201)1 Bjarnadottir T.K.... Schioeth H.B. (Genomics 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 139378 HGNC: 18992 AceView: GPR112 Ensembl:ENSG00000156920 euGenes: HUgn139378
    ECgene: GPR112 H-InvDB: GPR112

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GPR112 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GPR112 gene:
    Search GeneIP for patents involving GPR112

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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