Aliases for GPLD1 Gene
External Ids for GPLD1 Gene
Previous GeneCards Identifiers for GPLD1 Gene
Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]
GeneCards Summary for GPLD1 Gene
GPLD1 (Glycosylphosphatidylinositol Specific Phospholipase D1) is a Protein Coding gene. Among its related pathways are Phospholipase-C Pathway and Glycosylphosphatidylinositol (GPI)-anchor biosynthesis. GO annotations related to this gene include sodium channel regulator activity and glycosylphosphatidylinositol phospholipase D activity.
UniProtKB/Swiss-Prot for GPLD1 Gene
This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane.