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Aliases for GPI Gene

Aliases for GPI Gene

  • Glucose-6-Phosphate Isomerase 2 3 5
  • Autocrine Motility Factor 3 4
  • Phosphoglucose Isomerase 3 4
  • Phosphohexose Isomerase 3 4
  • Neuroleukin 3 4
  • EC 5.3.1.9 4 61
  • SA-36 3 4
  • PGI 3 4
  • AMF 3 4
  • NLK 3 4
  • PHI 3 4
  • Hexose Monophosphate Isomerase 3
  • Glucose Phosphate Isomerase 2
  • Hexosephosphate Isomerase 3
  • Phosphosaccharomutase 3
  • Phosphohexomutase 3
  • Sperm Antigen-36 3
  • Sperm Antigen 36 4
  • Oxoisomerase 3
  • GNPI 3
  • SA36 3

External Ids for GPI Gene

Previous GeneCards Identifiers for GPI Gene

  • GC19P035473
  • GC19P035305
  • GC19P039531
  • GC19P039547
  • GC19P034855
  • GC19P031360

Summaries for GPI Gene

Entrez Gene Summary for GPI Gene

  • This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]

GeneCards Summary for GPI Gene

GPI (Glucose-6-Phosphate Isomerase) is a Protein Coding gene. Diseases associated with GPI include Hemolytic Anemia, Nonspherocytic, Due To Glucose Phosphate Isomerase Deficiency and Hemolytic Anemia. Among its related pathways are Glucose metabolism and Innate Immune System. GO annotations related to this gene include cytokine activity and monosaccharide binding.

UniProtKB/Swiss-Prot for GPI Gene

  • Besides its role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.

Gene Wiki entry for GPI Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPI Gene

Genomics for GPI Gene

Regulatory Elements for GPI Gene

Enhancers for GPI Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G034316 1.3 Ensembl ENCODE 10.9 -40.9 -40949 4.7 HDGF PKNOX1 ATF1 FEZF1 ZNF2 TCF12 ZNF121 ZNF766 GATA2 ZNF416 KIAA0355 LSM14A ZNF792 GPI GC19P034326 RPL29P33
GH19G034232 1.1 Ensembl ENCODE 10.6 -126.3 -126349 1.9 HDAC1 ZNF2 GATA2 RELB FOS IKZF2 ZNF362 ZEB2 ZFP69B NFIC GPI LSM14A KIAA0355 GC19P034201
GH19G034458 0.7 ENCODE 10.7 +101.2 101152 3.8 RFX1 ZNF132 ZNF280D CBX3 ZNF571 ZNF175 ZNF507 ZFP41 FOSL1 ZNF148 GPI WTIP KIAA0355 GC19P034452
GH19G034235 0.7 ENCODE 10.6 -123.1 -123112 1.0 ZNF362 ZNF792 BHLHE40 ZIC2 EP300 OSR2 ZFHX2 POLR2A PATZ1 HNF4A GPI LSM14A KIAA0355 GC19P034201
GH19G034459 0.6 ENCODE 10.8 +98.6 98631 0.2 ZNF217 GATA3 NFIB FEZF1 DPF2 ZNF112 ZNF507 GPI GC19P034452 WTIP
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPI on UCSC Golden Path with GeneCards custom track

Promoters for GPI Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000108890 -80 801 HDGF PKNOX1 MLX CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for GPI Gene

Chromosome:
19
Start:
34,359,480 bp from pter
End:
34,402,413 bp from pter
Size:
42,934 bases
Orientation:
Plus strand

Genomic View for GPI Gene

Genes around GPI on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPI Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPI Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPI Gene

Proteins for GPI Gene

  • Protein details for GPI Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P06744-G6PI_HUMAN
    Recommended name:
    Glucose-6-phosphate isomerase
    Protein Accession:
    P06744
    Secondary Accessions:
    • B4DG39
    • Q9BRD3
    • Q9BSK5
    • Q9UHE6

    Protein attributes for GPI Gene

    Size:
    558 amino acids
    Molecular mass:
    63147 Da
    Quaternary structure:
    • Homodimer in the catalytically active form, monomer in the secreted form.

    Three dimensional structures from OCA and Proteopedia for GPI Gene

    Alternative splice isoforms for GPI Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GPI Gene

Selected DME Specific Peptides for GPI Gene

P06744:
  • WKGYTGK
  • PYDQYLHR
  • GVELGKQLA
  • QLIHQGT
  • SKTFTTQET
  • QHAFYQL
  • AQTEALM
  • ASKTFTT
  • LPYDQYL
  • LGIWYINCFGCET
  • MVTEALK
  • GTNGQHA
  • FYQLIHQ
  • VFEGNRP
  • NMFEFWD
  • FDQWGVE
  • KMKSFCQRV
  • FEQLLSGAH
  • DYSKNLV
  • GGSDLGP
  • KVKEFGID
  • WGEPGTN
  • GNRPTNSI
  • TTPLEKN
  • STNGLIN
  • DGKDVMP
  • IEPELDGS
  • SNIDGTH
  • HRFAAYFQQG
  • RFNHFSL
  • LALLGIWY
  • LLPHKVF
  • YEHKIFVQG
  • GEPGTNGQH
  • RVRSGDW
  • WVGGRYS
  • VLHVALR
  • MFNGEKIN
  • WDWVGGR
  • GFDNFEQLL
  • DMESNGK
  • SLWSAIGL
  • ALRNRSN
  • TGPIVWG
  • VAKHFVA
  • LAQTEAL
  • DQWGVELGK

Post-translational modifications for GPI Gene

  • ISGylated.
  • Phosphorylation at Ser-185 by CK2 has been shown to decrease enzymatic activity and may contribute to secretion by a non-classical secretory pathway.
  • Ubiquitination at isoforms=212, isoforms=273, posLast=8989, isoforms=2124, isoforms=2194, isoforms=2226, isoforms=2241, posLast=362362, isoforms=2423, and posLast=466466
  • Modification sites at PhosphoSitePlus

Domains & Families for GPI Gene

Suggested Antigen Peptide Sequences for GPI Gene

Graphical View of Domain Structure for InterPro Entry

P06744

UniProtKB/Swiss-Prot:

G6PI_HUMAN :
  • Belongs to the GPI family.
Family:
  • Belongs to the GPI family.
genes like me logo Genes that share domains with GPI: view

No data available for Gene Families for GPI Gene

Function for GPI Gene

Molecular function for GPI Gene

GENATLAS Biochemistry:
glucose phosphate isomerase (neuroleukin),glycolysis,gluconeogenesis,energy pathways
UniProtKB/Swiss-Prot CatalyticActivity:
D-glucose 6-phosphate = D-fructose 6-phosphate.
UniProtKB/Swiss-Prot Function:
Besides its role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.

Enzyme Numbers (IUBMB) for GPI Gene

Gene Ontology (GO) - Molecular Function for GPI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004347 glucose-6-phosphate isomerase activity IEA,TAS --
GO:0005125 cytokine activity IEA --
GO:0008083 growth factor activity IEA --
GO:0016853 isomerase activity IEA --
GO:0016866 intramolecular transferase activity IEA --
genes like me logo Genes that share ontologies with GPI: view
genes like me logo Genes that share phenotypes with GPI: view

Human Phenotype Ontology for GPI Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Animal Models , Transcription Factor Targets and HOMER Transcription for GPI Gene

Localization for GPI Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPI Gene

Cytoplasm. Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPI gene
Compartment Confidence
plasma membrane 5
extracellular 5
nucleus 5
cytosol 5
mitochondrion 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for GPI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IEA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS,IDA --
genes like me logo Genes that share ontologies with GPI: view

Pathways & Interactions for GPI Gene

genes like me logo Genes that share pathways with GPI: view

UniProtKB/Swiss-Prot P06744-G6PI_HUMAN

  • Pathway: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.

SIGNOR curated interactions for GPI Gene

Activates:

Gene Ontology (GO) - Biological Process for GPI Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001525 angiogenesis IEA --
GO:0001701 in utero embryonic development IEA --
GO:0001707 mesoderm formation IEA --
GO:0005975 carbohydrate metabolic process NAS 8575767
GO:0006094 gluconeogenesis IEA,TAS --
genes like me logo Genes that share ontologies with GPI: view

Drugs & Compounds for GPI Gene

(26) Drugs for GPI Gene - From: DrugBank, ClinicalTrials, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Tirofiban Approved Pharma 37
Clopidogrel Approved Nutra P2Y12 receptor antagonist 778
D-glucose Approved Pharma 0
Glucose 6-phosphate Experimental Pharma Target 0
fructose-6-phosphate Experimental Pharma Target 0

(30) Additional Compounds for GPI Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Beta-D-Fructose 6-phosphate
  • beta-D-Fructose 6-phosphate
Fructose 6-phosphate
  • D-Fructose 6-phosphate
  • D-Fructose 6-phosphorate
  • D-Fructose 6-phosphoric acid
  • D-Fructose-6-P
  • D-Fructose-6-phosphate
643-13-0
genes like me logo Genes that share compounds with GPI: view

Transcripts for GPI Gene

Unigene Clusters for GPI Gene

Glucose-6-phosphate isomerase:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPI Gene

ExUns: 1 ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a ·
SP1: - - -
SP2: -
SP3:
SP4: - - - - -
SP5: - -
SP6: - -
SP7:
SP8: - - -
SP9:
SP10:

ExUns: 16b ^ 17a · 17b ^ 18 ^ 19a · 19b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7: - -
SP8:
SP9:
SP10:

Relevant External Links for GPI Gene

GeneLoc Exon Structure for
GPI
ECgene alternative splicing isoforms for
GPI

Expression for GPI Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GPI Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for GPI Gene



Protein tissue co-expression partners for GPI Gene

NURSA nuclear receptor signaling pathways regulating expression of GPI Gene:

GPI

SOURCE GeneReport for Unigene cluster for GPI Gene:

Hs.466471

Evidence on tissue expression from TISSUES for GPI Gene

  • Heart(5)
  • Liver(5)
  • Nervous system(5)
  • Skin(4.9)
  • Kidney(4.7)
  • Blood(4.6)
  • Eye(4.6)
  • Intestine(4.4)
  • Adrenal gland(4.3)
  • Lung(4.2)
  • Stomach(3.9)
  • Muscle(3.5)
  • Gall bladder(3.4)
  • Pancreas(3.2)
  • Bone marrow(2.6)
  • Spleen(2.5)
  • Thyroid gland(2.5)
  • Saliva(2.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for GPI Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • skeletal muscle
Organs:
Head and neck:
  • brain
  • eye
  • head
  • mouth
Abdomen:
  • abdominal wall
  • biliary tract
  • gallbladder
  • liver
  • pancreas
  • spleen
General:
  • blood
  • coagulation system
  • peripheral nerve
  • peripheral nervous system
  • red blood cell
  • skin
  • white blood cell
genes like me logo Genes that share expression patterns with GPI: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPI Gene

Orthologs for GPI Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GPI Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPI 34 35
  • 99.66 (n)
cow
(Bos Taurus)
Mammalia GPI 34 35
  • 90.41 (n)
dog
(Canis familiaris)
Mammalia GPI 34 35
  • 90.32 (n)
mouse
(Mus musculus)
Mammalia Gpi1 34 16 35
  • 86.26 (n)
Gm1840 35
  • 86 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Gpi 34
  • 86.18 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 80 (a)
OneToMany
-- 35
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia GPI 35
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPI 34 35
  • 75.7 (n)
lizard
(Anolis carolinensis)
Reptilia GPI 35
  • 78 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpi 34
  • 73.2 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.5194 34
zebrafish
(Danio rerio)
Actinopterygii gpia 34 35
  • 75 (a)
gpib 34 35
  • 73.3 (n)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.8771 34
fruit fly
(Drosophila melanogaster)
Insecta Pgi 36 34 35
  • 67.21 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP012167 34
  • 66.42 (n)
worm
(Caenorhabditis elegans)
Secernentea Y87G2A.8 36
  • 68 (a)
gpi-1 34 35
  • 62.04 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AEL249C 34
  • 61.04 (n)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PGI1 34 35 37
  • 57.93 (n)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E23519g 34
  • 57.19 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT5G42740 34
  • 52.98 (n)
rice
(Oryza sativa)
Liliopsida Os03g0776000 34
  • 52.36 (n)
barley
(Hordeum vulgare)
Liliopsida Hv.2000 34
corn
(Zea mays)
Liliopsida Zm.3318 34
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 64 (a)
OneToOne
bread mold
(Neurospora crassa)
Ascomycetes NCU07281 34
  • 62.19 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes pgi1 34
  • 58.64 (n)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.3328 34
Species where no ortholog for GPI was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPI Gene

ENSEMBL:
Gene Tree for GPI (if available)
TreeFam:
Gene Tree for GPI (if available)

Paralogs for GPI Gene

No data available for Paralogs for GPI Gene

Variants for GPI Gene

Sequence variations from dbSNP and Humsavar for GPI Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs137853582 Pathogenic, Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470] 34,377,575(+) TTGGC(A/G)GCTCC intron-variant, reference, missense
rs137853583 Pathogenic, Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470] 34,394,044(+) GCACC(A/G/T)CTTTG reference, missense
rs137853584 Pathogenic, Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470] 34,399,933(+) GAAAA(C/G/T)AGAGC reference, missense
rs137853585 Pathogenic, Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470] 34,399,974(+) CTCAC(A/G)ACGCT reference, missense
rs137853586 Pathogenic, Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470] 34,365,325(+) CGAGC(A/C)CCGCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for GPI Gene

Variant ID Type Subtype PubMed ID
esv2864 OTHER complex 18987735
esv3644206 CNV loss 21293372
esv6365 CNV loss 19470904
nsv1138697 CNV deletion 24896259
nsv509738 CNV insertion 20534489
nsv953279 CNV deletion 24416366

Variation tolerance for GPI Gene

Residual Variation Intolerance Score: 32.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.50; 43.73% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPI Gene

Human Gene Mutation Database (HGMD)
GPI
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPI

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPI Gene

Disorders for GPI Gene

MalaCards: The human disease database

(18) MalaCards diseases for GPI Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
hemolytic anemia, nonspherocytic, due to glucose phosphate isomerase deficiency
  • nonspherocytic hemolytic anemia due to glucose phosphate isomerase deficiency
hemolytic anemia
  • anemia hemolytic
congenital nonspherocytic hemolytic anemia
  • hereditary nonspherocytic hemolytic anemia
glucose phosphate isomerase deficiency
  • glucose-6-phosphate isomerase deficiency
glucosephosphate isomerase deficiency
  • glucose phosphate isomerase deficiency
- elite association - COSMIC cancer census association via MalaCards
Search GPI in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

G6PI_HUMAN
  • Hemolytic anemia, non-spherocytic, due to glucose phosphate isomerase deficiency (HA-GPID) [MIM:613470]: A form of anemia in which there is no abnormal hemoglobin or spherocytosis. It is caused by glucose phosphate isomerase deficiency. {ECO:0000269 PubMed:7989588, ECO:0000269 PubMed:8499925, ECO:0000269 PubMed:8822952, ECO:0000269 PubMed:8822954, ECO:0000269 PubMed:9446754, ECO:0000269 PubMed:9856489}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Genatlas disease for GPI Gene

hemolytic anemia,hydrops fetalis

Relevant External Links for GPI

Genetic Association Database (GAD)
GPI
Human Genome Epidemiology (HuGE) Navigator
GPI
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPI
genes like me logo Genes that share disorders with GPI: view

Publications for GPI Gene

  1. Glucosephosphate isomerase (GPI) deficiency mutations associated with hereditary nonspherocytic hemolytic anemia (HNSHA). (PMID: 9446754) Beutler E. … Forman L. (Blood Cells Mol. Dis. 1997) 3 4 22 46 64
  2. Characterization of the 5' end of the gene for human glucose phosphate isomerase (GPI). (PMID: 2387591) Walker J.I.H. … Morgan M.J. (Genomics 1990) 2 3 4 22 64
  3. Differential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase CK2 phosphorylation. (PMID: 15637053) Yanagawa T. … Raz A. (J. Biol. Chem. 2005) 3 4 22 64
  4. Crystal structure of human phosphoglucose isomerase and analysis of the initial catalytic steps. (PMID: 12573240) Cordeiro A.T. … Thiemann O.H. (Biochim. Biophys. Acta 2003) 3 4 22 64
  5. Cloning of a glucose phosphate isomerase/neuroleukin-like sperm antigen involved in sperm agglutination. (PMID: 10727272) Yakirevich E. … Naot Y. (Biol. Reprod. 2000) 3 4 22 64

Products for GPI Gene

Sources for GPI Gene

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