GPD1 Gene
protein-coding GIFtS : 68 GCID: GC12 P050497
Glycerol-3-Phosphate Dehydrogenase 1 (Soluble)
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Aliasesfor GPD1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Glycerol-3-Phosphate Dehydrogenase 1 (Soluble) 1 2 Glycerol-3-Phosphate Dehydrogenase [NAD(+)], Cytoplasmic2 GPD-C2 3 Glycerol-3-Phosphate Dehydrogenase [NAD+], Cytoplasmic2 GPDH-C2 3 Glycerophosphate Dehydrogenase2 EC 1.1.1.83 8 EC 1.1.18 HTGTI2
Export aliases for GPD1 gene to outside databases Previous GC identifers: GC12P050792 GC12P050553 GC12P050214 GC12P048784 GC12P047531
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Summariesfor GPD1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for GPD1 Gene: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Mar 2012) GeneCards Summary for GPD1 Gene: GPD1 (glycerol-3-phosphate dehydrogenase 1 (soluble)) is a protein-coding gene. Diseases associated with GPD1 include lactate dehydrogenase a deficiency infantile regressive hypertriglyceridemia and hepatosteatosis related super-pathways are Glycerophospholipid biosynthesis and Metabolic pathways . GO annotations related to this gene include glycerol-3-phosphate dehydrogenase [NAD+] activity and protein homodimerization activity . An important paralog of this gene is GPD1L .
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Genomic Viewsfor GPD1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000012.11 NC_018923.2 NT_029419.12 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GPD1 gene promoter:Lmo2 Olf-1 NF-kappaB AP-2gamma AREB6 S8 FOXC1 HSF2 NF-kappaB1 Other transcription factors Search SABiosciences Chromatin IP Primers for GPD1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPD1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 12q13.12 Ensembl cytogenetic band: 12q13.12 HGNC cytogenetic band: 12q13.12 GPD1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 12 GeneLoc Exon Structure
GeneLoc location for GC12P050497: view genomic region
(about GC identifiers )
Start: 50,497,602 bp from pter End:
50,505,102 bp from pter
Size: 7,501 bases Orientation:
plus strand
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Proteinsfor GPD1 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: GPDA_HUMAN, P21695 See
protein sequence )Recommended Name: Size : 349 amino acids; 37568 DaSubunit : HomodimerSubcellular location : Cytoplasm3 PDB 3D structures from :1WPQ (3D) 1X0V (3D) 1X0X (3D) Secondary accessions : F8W1L5 Q8N1B0Alternative splicing : 2 isoforms : P21695-1 P21695-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for GPD1: NX_P21695 Explore proteomics data for GPD1 at MOPED Post-translational modifications:
View modification sites using PhosphoSitePlus View neXtProt modification sites for NX_P21695 4/21 DME Specific Peptides for GPD1 (P21695 ) (see all 21 )GPD1 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins (2 alternative transcripts): NP_001244128.1 NP_005267.2 ENSEMBL proteins: ENSP00000301149 ENSP00000448244 ENSP00000446768 Reactome Protein details: P21695 Human Recombinant Protein Products for GPD1: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing GPD1 Antibody Products: Assay Products for GPD1:
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Protein
Domains /for GPD1 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section 5/7 InterPro protein domains (see all 7 ):
Graphical View of Domain Structure for InterPro Entry P21695 ProtoNet protein and cluster: P21695
1 Blocks protein domain : IPB006168 UniProtKB/Swiss-Prot: GPDA_HUMAN, P21695 Similarity : Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase familyAbout GeneDecksing
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Functionfor GPD1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: GPDA_HUMAN, P21695 Catalytic activity : sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADHEnzyme regulation : Inhibited by zinc ions and sulfate
Genatlas biochemistry entry for GPD1 glycerol-3-phosphate dehydrogenase,NAD dependent,cytoplasmic Enzyme Numbers (IUBMB): EC 1.1.1.8 1 2 EC 1.1.1 2 Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity
IEA -- GO:0004368 glycerol-3-phosphate dehydrogenase activity
IEA -- GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
-- -- GO:0042803 protein homodimerization activity
IEA -- GO:0051287 NAD binding
IEA --
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for GPD1 :3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gpd1) :About GeneDecksing Animal Models: In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPD1
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Pathways & Interactionsfor GPD1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for GPD1 About (see all 7 ) See pathways by source SuperPath Contained pathways About 1 Glycerophospholipid biosynthesis 2 Metabolism 3 Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) 4 Fatty Acyl-CoA Biosynthesis 5 Acyl chain remodelling of PE
Pathways by source See SuperPaths Show all pathways 2 5/7 (see all 7 )1 (Kegg details for GPD1) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GPD1 STRING Interaction
Network Preview (showing 5 interactants - click image to see 17)5/46 Interacting proteins for GPD1 (P21695 2 , 3 ENSP00000301149 4 via UniProtKB, MINT, STRING , and/or I2D (see all 46 )About this table Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16 ): About this table
About GeneDecksing
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Drugs & Compoundsfor GPD1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
IUPHAR ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for GPD1 (GPDA) 4 HMDB Compounds for GPD1 About this table 1 DrugBank Compound for GPD1 About this table 10/41 Novoseek inferred chemical compound relationships for GPD1 gene (see all 41 ) About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
glycerol 3-phosphate
98
269
10190973 (6), 14605988 (5), 12548942 (5), 2226800 (3) (see
all 99 )
dhap
67
5
16460752 (2), 18376850 (1)
troglitazone
57.9
3
12861228 (1), 12895585 (1), 16483873 (1)
lipid
57.9
36
14605988 (2), 1976021 (1), 8126079 (1), 9062891 (1) (see
all 27 )
succinate
56.7
14
8351966 (2), 9431688 (2), 8130177 (1), 7812436 (1) (see
all 11 )
fatty acid
56.6
29
12643487 (1), 9075710 (1), 11606486 (1), 14605988 (1) (see
all 18 )
ibmx
56.1
1
12861228 (1)
glycerol
52.8
23
12548942 (5), 7812436 (1), 17242918 (1), 14524727 (1) (see
all 5 )
6-phosphogluconate
50.4
3
14605988 (1), 12196534 (1), 12604241 (1)
glyceraldehyde 3-phosphate
48.1
6
9831620 (1), 10336621 (1), 1315269 (1), 16913842 (1) (see
all 6 )
GPD1 / GPDA
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Transcriptsfor GPD1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for GPD1 gene (2 alternative transcripts): NM_001257199.1 NM_005276.3 Unigene Cluster for GPD1:
Glycerol-3-phosphate dehydrogenase 1 (soluble) Hs.524418 [show with all ESTs ] Unigene Representative Sequence: NM_005276 7 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000301149 (uc001rvz.3 uc001rwa.3 ) ENST00000547964 ENST00000551939 (uc010smp.1 )ENST00000547190 ENST00000548814 ENST00000548152 ENST00000550172 Congresses - knowledge worth sharing: European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014 Primer GPD1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AK130162.1 AK295911.1 AK312516.1 BC032234.1 L34041.1
5 DOTS entries : DT.113922 DT.92021196
DT.100785873 DT.95327703 DT.121193033 24/207 AceView cDNA sequences (see all 207 ):
BM918911 CA306021 CD515894 BP381758 CB154050 AU122033 BI759262 BP381762 CR593251 BM547808 H26339 BQ721700 NM_005276 BP381755 BM701059 BI833137 AA341745 BQ184145 BM672380 BC032234 AW473816 CA427025 BP381824 AI609131 GeneLoc Exon Structure 5/7 Alternative Splicing Database (ASD) splice patterns (SP) for GPD1 (see all 7 ) About this scheme ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13 ^ 14 SP1 : - - - - - SP2 : - - - - SP3 : - - - - - - SP4 : - - SP5 : - - -
ECgene alternative splicing isoforms for GPD1
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Expression for GPD1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GPD1 expression in normal human tissues
(normalized intensities) GPD1 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: CCTGGCATCTAbout this image
GPD1 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/9 selected tissues (see all 9 ) fully expand See GPD1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GPD1 SOURCE GeneReport for Unigene cluster: Hs.524418 SABiosciences Expression via Pathway-Focused PCR Arrays including GPD1 : Primer GPD1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPD1
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Orthologsfor GPD1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for GPD1 gene from 10/24 species (see all 24 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Gpd11 5
glycerol-3-phosphate dehydrogenase 1 (soluble)1, 5
89.59(n) 1 93.98(a) 1
15 (56.13 cM) 5 14555 1 NM_010271.2 1 NP_034401.1 1 99717515 5
chicken Aves LOC4268811
glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic-like less
75.26(n) 79.37(a)
426881 XM_003643117.1 XP_003643165.1
lizard Reptilia GPD16
Uncharacterized protein
84(a)
1 ↔ 1
2(91633778-91651523)
African clawed frog Amphibia Xl.24782
Xenopus laevis, Similar to glycerol phosphate dehydrogenase 1, cytoplasmic adult, clone IMAGE4888802, mRNA, partial cds less
76.12(n)
BC043631.1
zebrafish Actinopterygii wufc30a072
Danio rerio glycerol-3-phosphate dehydrogenase 1, mRNA (cDNA clone MGC63859 IMAGE6789017), complete cds less
78.01(n)
BC053116.1
fruit fly Insecta Gpdh1 3
glycerophosphate shuttleless 3 1
65(a) 3 67.91(n) 1 66.67(a) 1
26A33 33824 1 NM_057218.3 1 NP_476566.1 1
worm Secernentea F47G4.33 1
NAD-dependent glycerol-3-phosphateless 3 1
50(a) 3 59.58(n) 1 61.49(a) 1
I(14083918-14086109)3 176399 1 NM_181903.4 1 NP_871632.1 1
baker's yeast Saccharomycetes GPD1(YDL022W)4 1
NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p less 4 1
53.47(n) 1 50.76(a) 1
4(411825-413000) 4 851539 1, 4 NP_010262.1 1, 4
thale cress eudicotyledons AT5G406101
glycerol-3-phosphate dehydrogenase [NAD+]
57.19(n) 53.21(a)
834060 NM_123425.4 NP_198877.1
rice Liliopsida Os.248912
Oryza sativa (japonica cultivar-group) cDNA cloneJ023050E11, full insert sequence less
76.79(n)
AK070366.1
ENSEMBL Gene Tree for GPD1 (if available)TreeFam Gene Tree for GPD1 (if available)
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Paralogsfor GPD1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for GPD1 gene GPD1L 2 1 SIMAP similar gene for GPD1 using alignment to 2 protein entries: GPDA_HUMAN (see all proteins ):GPD1L About GeneDecksing
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Genomic Variantsfor GPD1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 12 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for GPD1 (50497602 - 50505102 bp)
Structural Variations Database of Genomic Variants (DGV) variations for GPD1: -- Human Gene Mutation Database (HGMD) : GPD1 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor GPD1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Novoseek , Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 138420
OMIM disorders : --UniProtKB/Swiss-Prot: GPDA_HUMAN, P21695 Hypertriglyceridemia, transient infantile (HTGTI) [MIM:614480]: An autosomal recessive disorder characterized by onset of moderate to severe transient hypertriglyceridemia in infancy that normalizes with age. The hypertriglyceridemia is associated with hepatomegaly, moderately elevated transaminases, persistent fatty liver, and the development of hepatic fibrosis. Note=The disease is caused by mutations affecting the gene represented in this entry 20/24 (see all 24 ): About MalaCards lactate dehydrogenase a deficiency infantile regressive hypertriglyceridemia and hepatosteatosis hypertriglyceridemia brugada syndrome sleep apnea cleft lip liposarcoma cleft palate albinism duodenitis acute leukemia obesity blindness myopathy colorectal cancer insulin resistance pneumonia diabetes mellitus tuberculosis alcoholism 3 Novoseek inferred disease relationships for GPD1 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
obesity
53.9
2
20404019 (1), 7857262 (1)
necrosis
0.704
1
9492058 (1)
tumors
0
1
9492058 (1)
Export disorders for GPD1 gene to outside databases
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Publicationsfor GPD1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for GPD1 gene, integrated from 9 sources (see all 192 ):(articles sorted by number of sources associating them with GPD1) Utopia : connect your pdf to the dynamic
Crystal structures of human glycerol 3-phosphate dehydrogenase 1 (GPD1). (PubMed id 16460752) 1 , 2 , 9(2006) Sequence conservation and structural organization of the glycerol-3- phosphate dehydrogenase promoter in mice and humans. (PubMed id 2398890) 1 , 2 , 9(1990) Transient infantile hypertriglyceridemia, fatty liver, and hepatic fibrosis caused by mutated GPD1, encoding glycerol-3-phosphate dehydrogenase 1. (PubMed id 22226083) 1 , 2 (2012) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Molecular cloning, sequencing and expression of a cDNA encoding a human liver NAD-dependent alpha-glycerol-3-phosphate dehydrogenase. (PubMed id 7772607) 1 , 2 (1995) The influence of obstructive sleep apnea on the expre ssion of glycerol-3-phosphate dehydrogenase 1 gene. (PubMed id 20404019) 1 , 9(2010) Ability of cytosolic malate dehydrogenase and lactate dehydrogenase to increase the ratio of NADPH to NADH oxidation by cytosolic glycerol-3-phosphate dehydrogenase. (PubMed id 10190973) 1 , 9(1999) GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle. (PubMed id 16849634) 1 , 9(2006) Enhanced glycerol 3-phosphate dehydrogenase activity in adipose tissue of obese humans. (PubMed id 14674682) 1 , 9(2003) Initial characterization of the human central proteome. (PubMed id 21269460) 2 (2011)
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External Searches for GPD1 gene
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Genome Databases showing GPD1 gene
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Specialized Databases showing GPD1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for GPD1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for GPD1 gene: GPD1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor GPD1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GPD1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GPD1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Recombinant Protein for GPD1
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GPD1
ThermoFisher Antibody for GPD1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat GPD1
LSBio Antibodies in human mouse rat
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and Proteopedia 
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