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Aliases for GPBP1L1 Gene

Aliases for GPBP1L1 Gene

  • GC-Rich Promoter Binding Protein 1 Like 1 2 3
  • GC-Rich Promoter Binding Protein 1-Like 1 2 3 5
  • GC-Rich Promoter-Binding Protein 1-Like 1 3 4
  • SP192 3

External Ids for GPBP1L1 Gene

Previous GeneCards Identifiers for GPBP1L1 Gene

  • GC01M045763
  • GC01M045865
  • GC01M046092
  • GC01M044204

Summaries for GPBP1L1 Gene

GeneCards Summary for GPBP1L1 Gene

GPBP1L1 (GC-Rich Promoter Binding Protein 1 Like 1) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding. An important paralog of this gene is GPBP1.

UniProtKB/Swiss-Prot for GPBP1L1 Gene

  • Possible transcription factor.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPBP1L1 Gene

Genomics for GPBP1L1 Gene

Regulatory Elements for GPBP1L1 Gene

Promoters for GPBP1L1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GPBP1L1 on UCSC Golden Path with GeneCards custom track

Genomic Location for GPBP1L1 Gene

45,627,304 bp from pter
45,688,113 bp from pter
60,810 bases
Minus strand

Genomic View for GPBP1L1 Gene

Genes around GPBP1L1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPBP1L1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPBP1L1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPBP1L1 Gene

Proteins for GPBP1L1 Gene

  • Protein details for GPBP1L1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Vasculin-like protein 1
    Protein Accession:
    Secondary Accessions:
    • D3DQ10
    • Q9H751

    Protein attributes for GPBP1L1 Gene

    474 amino acids
    Molecular mass:
    52302 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPBP1L1 Gene

Proteomics data for GPBP1L1 Gene at MOPED

Post-translational modifications for GPBP1L1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GPBP1L1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GPBP1L1 Gene

Domains & Families for GPBP1L1 Gene

Protein Domains for GPBP1L1 Gene


Suggested Antigen Peptide Sequences for GPBP1L1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the vasculin family.
  • Belongs to the vasculin family.
genes like me logo Genes that share domains with GPBP1L1: view

No data available for Gene Families for GPBP1L1 Gene

Function for GPBP1L1 Gene

Molecular function for GPBP1L1 Gene

UniProtKB/Swiss-Prot Function:
Possible transcription factor.
genes like me logo Genes that share phenotypes with GPBP1L1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPBP1L1 Gene

Localization for GPBP1L1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPBP1L1 Gene

Subcellular locations from

Jensen Localization Image for GPBP1L1 Gene COMPARTMENTS Subcellular localization image for GPBP1L1 gene
Compartment Confidence
nucleus 5
cytosol 2
plasma membrane 2
golgi apparatus 1

No data available for Gene Ontology (GO) - Cellular Components for GPBP1L1 Gene

Pathways & Interactions for GPBP1L1 Gene

SuperPathways for GPBP1L1 Gene

No Data Available

Interacting Proteins for GPBP1L1 Gene

Gene Ontology (GO) - Biological Process for GPBP1L1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045893 positive regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with GPBP1L1: view

No data available for Pathways by source and SIGNOR curated interactions for GPBP1L1 Gene

Drugs & Compounds for GPBP1L1 Gene

No Compound Related Data Available

Transcripts for GPBP1L1 Gene

Unigene Clusters for GPBP1L1 Gene

GC-rich promoter binding protein 1-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPBP1L1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15a · 15b ^ 16
SP1: - - -
SP2: -
SP3: - - -
SP4: - -
SP6: -

Relevant External Links for GPBP1L1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GPBP1L1 Gene

mRNA expression in normal human tissues for GPBP1L1 Gene

Protein differential expression in normal tissues from HIPED for GPBP1L1 Gene

This gene is overexpressed in CD8 Tcells (28.1), Testis (22.7), and Platelet (12.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for GPBP1L1 Gene

SOURCE GeneReport for Unigene cluster for GPBP1L1 Gene Hs.238432

genes like me logo Genes that share expression patterns with GPBP1L1: view

Protein tissue co-expression partners for GPBP1L1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPBP1L1 Gene

Orthologs for GPBP1L1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPBP1L1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia GPBP1L1 35
  • 91.84 (n)
  • 93.88 (a)
-- 36
  • 85 (a)
-- 36
  • 94 (a)
(Canis familiaris)
Mammalia GPBP1L1 35
  • 92.74 (n)
  • 95.35 (a)
GPBP1L1 36
  • 95 (a)
(Mus musculus)
Mammalia Gpbp1l1 35
  • 88.23 (n)
  • 89.79 (a)
Gpbp1l1 16
Gpbp1l1 36
  • 89 (a)
(Pan troglodytes)
Mammalia GPBP1L1 35
  • 99.51 (n)
  • 99.79 (a)
GPBP1L1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Gpbp1l1 35
  • 86.89 (n)
  • 89.64 (a)
(Monodelphis domestica)
Mammalia GPBP1L1 36
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia GPBP1L1 36
  • 84 (a)
(Gallus gallus)
Aves GPBP1L1 35
  • 79.72 (n)
  • 82.13 (a)
GPBP1L1 36
  • 82 (a)
(Anolis carolinensis)
Reptilia GPBP1L1 36
  • 82 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gpbp1l1 35
  • 66.81 (n)
  • 65.3 (a)
Str.5410 35
(Danio rerio)
Actinopterygii gpbp1l1 35
  • 64.49 (n)
  • 63.4 (a)
wufc48e01 35
gpbp1l1 36
  • 58 (a)
Species with no ortholog for GPBP1L1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GPBP1L1 Gene

Gene Tree for GPBP1L1 (if available)
Gene Tree for GPBP1L1 (if available)

Paralogs for GPBP1L1 Gene

Paralogs for GPBP1L1 Gene

(1) SIMAP similar genes for GPBP1L1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with GPBP1L1: view

Variants for GPBP1L1 Gene

Sequence variations from dbSNP and Humsavar for GPBP1L1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs36067922 - 45,640,380(-) AGCAA(C/T)CCTCC reference, missense
rs12093126 - 45,628,365(+) AACTG(C/T)GGCTC reference, missense
rs1250 -- 45,628,355(+) AACAG(A/G)CTGGA reference, synonymous-codon
rs4180 -- 45,627,735(+) AAAAA(A/C)AAAAA utr-variant-3-prime
rs1135812 -- 45,629,600(-) CTCAA(A/G/T)GAGTT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for GPBP1L1 Gene

Variant ID Type Subtype PubMed ID
nsv829726 CNV Loss 17160897
nsv871928 CNV Gain 21882294
nsv870511 CNV Gain 21882294

Variation tolerance for GPBP1L1 Gene

Residual Variation Intolerance Score: 44.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.98; 49.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPBP1L1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPBP1L1 Gene

Disorders for GPBP1L1 Gene

Relevant External Links for GPBP1L1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GPBP1L1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPBP1L1 Gene

Publications for GPBP1L1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 67
  2. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3

Products for GPBP1L1 Gene

Sources for GPBP1L1 Gene

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