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Aliases for GPATCH3 Gene

Aliases for GPATCH3 Gene

  • G-Patch Domain Containing 3 2 3 5
  • GPATC3 3 4
  • G Patch Domain-Containing Protein 3 3

External Ids for GPATCH3 Gene

Previous HGNC Symbols for GPATCH3 Gene

  • GPATC3

Previous GeneCards Identifiers for GPATCH3 Gene

  • GC01M027090
  • GC01M027216
  • GC01M025470

Summaries for GPATCH3 Gene

GeneCards Summary for GPATCH3 Gene

GPATCH3 (G-Patch Domain Containing 3) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPATCH3 Gene

Genomics for GPATCH3 Gene

Regulatory Elements for GPATCH3 Gene

Enhancers for GPATCH3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G026691 3.2 FANTOM5 Ensembl ENCODE dbSUPER 15.1 +204.0 204008 12.9 MLX CREB3L1 AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 HMGN2 NPM1P39 PIGV ACTG1P20 GPATCH3 ZNF593 LOC101928728 SFN ENSG00000226698 FAM46B
GH01G026990 2 FANTOM5 Ensembl ENCODE dbSUPER 22.1 -95.7 -95729 13.3 CREB3L1 MLX AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 GPATCH3 PIGV ACTG1P20 NR0B2 NUDC LOC101928728 HMGN2 NPM1P39 TRNP1 LOC101928324
GH01G026824 1.8 FANTOM5 ENCODE dbSUPER 22.6 +73.7 73712 6.5 CREB3L1 AGO1 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF548 ZNF263 SP3 ZDHHC18 ACTG1P20 HMGN2 ENSG00000231344 GPATCH3 NPM1P39 LOC101928324 ZNF593 SFN ENSG00000243659
GH01G026721 3.1 VISTA Ensembl ENCODE dbSUPER 9.7 +177.4 177411 3.9 HDGF PKNOX1 CREB3L1 ARNT WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 PIGV ARID1A SFN GPATCH3 NUDC TRNP1 LOC101928728 GC01P026765
GH01G026618 2.1 FANTOM5 Ensembl ENCODE dbSUPER 13 +280.7 280670 4.0 CREB3L1 AGO1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 HMGN2 ACTG1P20 ZNF593 AHDC1 LOC101928324 WASF2 NPM1P39 RPL17P9 ARID1A PIGV
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPATCH3 on UCSC Golden Path with GeneCards custom track

Promoters for GPATCH3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000003626 665 1601 PKNOX1 MLX CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143

Genomic Location for GPATCH3 Gene

Chromosome:
1
Start:
26,890,488 bp from pter
End:
26,901,065 bp from pter
Size:
10,578 bases
Orientation:
Minus strand

Genomic View for GPATCH3 Gene

Genes around GPATCH3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPATCH3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPATCH3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPATCH3 Gene

Proteins for GPATCH3 Gene

  • Protein details for GPATCH3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96I76-GPTC3_HUMAN
    Recommended name:
    G patch domain-containing protein 3
    Protein Accession:
    Q96I76
    Secondary Accessions:
    • Q5JYH2
    • Q8NDJ2
    • Q9H9Z3

    Protein attributes for GPATCH3 Gene

    Size:
    525 amino acids
    Molecular mass:
    59338 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAD38742.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for GPATCH3 Gene

Post-translational modifications for GPATCH3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GPATCH3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GPATCH3 Gene

Domains & Families for GPATCH3 Gene

Gene Families for GPATCH3 Gene

Protein Domains for GPATCH3 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GPATCH3: view

No data available for UniProtKB/Swiss-Prot for GPATCH3 Gene

Function for GPATCH3 Gene

Gene Ontology (GO) - Molecular Function for GPATCH3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with GPATCH3: view
genes like me logo Genes that share phenotypes with GPATCH3: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPATCH3 Gene

Localization for GPATCH3 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPATCH3 gene
Compartment Confidence
nucleus 3
cytosol 3
cytoskeleton 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GPATCH3 Gene

Pathways & Interactions for GPATCH3 Gene

SuperPathways for GPATCH3 Gene

No Data Available

Interacting Proteins for GPATCH3 Gene

Gene Ontology (GO) - Biological Process for GPATCH3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with GPATCH3: view

No data available for Pathways by source and SIGNOR curated interactions for GPATCH3 Gene

Drugs & Compounds for GPATCH3 Gene

No Compound Related Data Available

Transcripts for GPATCH3 Gene

mRNA/cDNA for GPATCH3 Gene

Unigene Clusters for GPATCH3 Gene

G patch domain containing 3:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPATCH3 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b
SP1: - -
SP2:
SP3:
SP4:
SP5: -

Relevant External Links for GPATCH3 Gene

GeneLoc Exon Structure for
GPATCH3
ECgene alternative splicing isoforms for
GPATCH3

Expression for GPATCH3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GPATCH3 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GPATCH3 Gene



Protein tissue co-expression partners for GPATCH3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GPATCH3 Gene:

GPATCH3

SOURCE GeneReport for Unigene cluster for GPATCH3 Gene:

Hs.10903

Evidence on tissue expression from TISSUES for GPATCH3 Gene

  • Nervous system(4.8)
  • Skin(4.1)
genes like me logo Genes that share expression patterns with GPATCH3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GPATCH3 Gene

Orthologs for GPATCH3 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPATCH3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPATCH3 34 35
  • 99.62 (n)
dog
(Canis familiaris)
Mammalia GPATCH3 34 35
  • 87.99 (n)
cow
(Bos Taurus)
Mammalia GPATCH3 34 35
  • 86.33 (n)
rat
(Rattus norvegicus)
Mammalia Gpatch3 34
  • 84.29 (n)
mouse
(Mus musculus)
Mammalia Gpatch3 34 16 35
  • 84.07 (n)
oppossum
(Monodelphis domestica)
Mammalia GPATCH3 35
  • 73 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPATCH3 34 35
  • 66.09 (n)
lizard
(Anolis carolinensis)
Reptilia GPATCH3 35
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpatch3 34
  • 61.39 (n)
African clawed frog
(Xenopus laevis)
Amphibia Xl.16274 34
zebrafish
(Danio rerio)
Actinopterygii gpatch3 34 35
  • 62.39 (n)
Dr.8730 34
worm
(Caenorhabditis elegans)
Secernentea K07B1.7 34 35
  • 48.18 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 43 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7955 34
Species where no ortholog for GPATCH3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPATCH3 Gene

ENSEMBL:
Gene Tree for GPATCH3 (if available)
TreeFam:
Gene Tree for GPATCH3 (if available)

Paralogs for GPATCH3 Gene

No data available for Paralogs for GPATCH3 Gene

Variants for GPATCH3 Gene

Sequence variations from dbSNP and Humsavar for GPATCH3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000217807 -- 26,897,915(+) GAGGA(C/T)TGCTT intron-variant
rs1000321399 -- 26,897,359(+) CTCCA(C/T)AGGGG reference, missense
rs1000324343 -- 26,898,924(+) CCTCC(C/G)AAAGT intron-variant
rs1000378599 -- 26,898,641(+) CCAAA(A/C)AATTT intron-variant
rs1000431171 -- 26,891,842(+) AGCTG(A/G)GATTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for GPATCH3 Gene

Variant ID Type Subtype PubMed ID
nsv1000012 CNV gain 25217958
nsv834524 CNV gain+loss 17160897

Variation tolerance for GPATCH3 Gene

Residual Variation Intolerance Score: 58.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.92; 35.75% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPATCH3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GPATCH3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPATCH3 Gene

Disorders for GPATCH3 Gene

Relevant External Links for GPATCH3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPATCH3

No disorders were found for GPATCH3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPATCH3 Gene

Publications for GPATCH3 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64

Products for GPATCH3 Gene

Sources for GPATCH3 Gene

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